The treatment of hypertension in patients with erectile dysfunction.

abstract：:Sodium meclofenamate (200 to 400 mg daily) was compared with aspirin (2.4 to 4.8 g daily) for the treatment of rheumatoid arthritis in a 6-month, double-blind, multicentre study. Two groups of patients participated, one receiving stabilized doses of concomitant gold or steroid therapy and one not receiving such therap...

journal_title：Current medical research and opinion

authors： Gowans JD

更新日期：1981-01-01 00:00:00

abstract：:Discussions on the healthy volunteer in clinical investigation do not attempt to define normality. In 34 healthy volunteers, 1653 biochemical and haematological tests were performed. The incidence of abnormal results was 11%. Only 4 subjects had all tests within normal limits and when these repeated only 1 subject sti...

journal_title：Current medical research and opinion

authors： Joubert P,Pannall P

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:Poor quality has been reported for some generics and other copies of original products. We performed a pilot study to compare the disintegration/dissolution profiles of FOSAMAX (alendronate) 70 mg tablets with those of copies of FOSAMAX that were manufactured outside the United States. RESEARCH DESIGN AND ME...

journal_title：Current medical research and opinion

authors： Epstein S,Cryer B,Ragi S,Zanchetta JR,Walliser J,Chow J,Johnson MA,Leyes AE

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To review the fatalities among children hospitalized with respiratory syncytial virus (RSV) infection, and identify factors leading to a fatal outcome. RESEARCH DESIGN AND METHODS:Review of literature identified from a structured search of PubMed (1966-2009) using the following Medical Subject Headings: resp...

journal_title：Current medical research and opinion

authors： Welliver RC Sr,Checchia PA,Bauman JH,Fernandes AW,Mahadevia PJ,Hall CB

更新日期：2010-09-01 00:00:00

abstract：:A double-blind trial was carried out on 116 patients with lower respiratory tract infection and systemic manifestations. One group received co-trimoxazole (480 mg. trimethoprim and 2,400 mg. sulphamethoxazole daily), and the other group received 2 g. tetracycline daily. The trial, as judged by clinical improvements, t...

journal_title：Current medical research and opinion

authors： Sallam MA,Sallam IA

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Resistance to endocrine treatment generally occurs over time, especially in the metastatic stage. In this paper, we aimed to review the mechanisms of cyclin-dependent kinase (CDK) 4/6 inhibition and clinical usage of new agents in the light of recent literature updates. SCOPE:A literature search was carried...

journal_title：Current medical research and opinion

authors： Bilgin B,Sendur MAN,Şener Dede D,Akıncı MB,Yalçın B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Vesicoureteral reflux (VUR) occurs in approximately 1% of infants and children and is associated with recurrent urinary tract infections (UTIs). The objective of this paper is to examine the use of endoscopic injection with dextranomer/hyaluronic acid copolymer (Dx/HA) as a curative option and as an alternati...

journal_title：Current medical research and opinion

authors： Elder JS,Shah MB,Batiste LR,Eaddy M

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To investigate the predictive factors associated with physical impairment among older patients with type 2 diabetes mellitus (T2DM) in Japan and to examine the potential impact of physical impairment on patient-reported health outcomes in this population. METHODS:A cross-sectional analysis was conducted usin...

journal_title：Current medical research and opinion

authors： Araki A,Umegaki H,Sakurai T,Mizuno Y,Miyao M,Imori M,Suzuki S,Cambron-Mellott MJ,Yokote K,Onuma T,Yokono K

更新日期：2020-11-23 00:00:00

abstract：OBJECTIVE:Patients receiving levodopa for Parkinson's disease experience motor fluctuations and immobility ('off' episodes) between doses. This study assessed adjunctive Zelapar (selegiline orally disintegrating tablet (ODT)) for managing off episodes and for long-term safety. METHODS:This open-label extension evaluat...

journal_title：Current medical research and opinion

authors： Lew MF,Pahwa R,Leehey M,Bertoni J,Kricorian G,Zydis Selegiline Study Group.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Inadequate removal of extracellular volume markedly increases blood pressure and contributes to high morbidity and mortality in hemodialysis patients. Advances in fluid management are needed to improve clinical outcomes. The aim of this quality improvement project was to examine the advantages of using a hem...

journal_title：Current medical research and opinion

authors： Balter P,Ficociello LH,Taylor PB,Usvyat L,Sawin DA,Mullon C,Diaz-Buxo J,Zabetakis P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Eribulin mesylate (eribulin) is indicated for patients with metastatic breast cancer (MBC) who have previously received at least two chemotherapies in the US and for patients with locally advanced breast cancer (LABC) or MBC who have progressed after at least one chemotherapy in the European Union (EU). In b...

journal_title：Current medical research and opinion

authors： Chabot I,Zhao Q,Su Y

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Calcipotriol 50 µg/g and betamethasone 0.5 mg/g dipropionate (Cal/BD) aerosol foam formulation provides greater effectiveness and improved patient preference compared with traditional Cal/BD formulations for the topical treatment of plaque psoriasis. OBJECTIVE:To determine the cost-effectiveness of Cal/BD f...

journal_title：Current medical research and opinion

authors： Foley P,Garrett S,Ryttig L

更新日期：2018-07-01 00:00:00

abstract：:A study was carried out in general practice to assess the clinical effectiveness and tolerability of the oral cephalosporin, cefuroxime axetil, in the treatment of 369 patients presenting with acute infections of the upper respiratory tract. The main diagnoses were tonsillitis, pharyngitis, sinusitis and otitis media....

journal_title：Current medical research and opinion

authors： Griffiths GK,VandenBurg MJ,Wight LJ,Gudgeon AC,Kelsey M

更新日期：1987-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice and has attracted much attention due to its association with a substantial mortality and morbidity, particularly from stroke, thromboembolism and heart failure. This Editorial Commentary provides a brief overview of the ...

journal_title：Current medical research and opinion

authors： Khoo CW,Lip GY

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Ocular surface disease (OSD) is a common side effect of ophthalmic medications containing the preservative benzalkonium chloride (BAK). Little is known whether and how glaucoma treatment patterns and annual costs vary based on the presence of BAK. The objective of this analysis was to estimate first-year trea...

journal_title：Current medical research and opinion

authors： Schmier JK,Covert DW,Robin AL

更新日期：2010-12-01 00:00:00

abstract：:A double-blind trial was carried out in 60 elderly patients with osteoarthritis of the knee or hip to compare the efficacy and tolerability of treatment with tiaprofenic acid and indomethacin. Patients received either 600 mg tiaprofenic acid or 100 mg indomethacin daily for 3 months. The results of assessments made ev...

journal_title：Current medical research and opinion

authors： Meurice J

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Insulin resistance alone does not result in the development of type 2 diabetes; progressive dysfunction of pancreatic islet alpha and beta cells, which results in inadequate control of hyperglycemia, must be present for the disease to develop. Because of these defects, meal-stimulated insulin secretion from ...

journal_title：Current medical research and opinion

authors： Meece J

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The pattern of renal transplantation has never been described since the introduction of the technique. The purpose of this study was therefore to characterise the pattern of renal transplantation from 1967 to 2000, focusing on renal graft function as a predictor of survival. METHODS:This study was a retrosp...

journal_title：Current medical research and opinion

authors： McEwan P,Baboolal K,Dixon S,Conway P,Currie CJ

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:This study proposed a conception of individualized chemotherapy based on organ selectivity of drug distribution by retrospectively comparing the effect of vinorelbine and capecitabine in patients with metastatic breast cancer. METHODS:Between January 2002 and December 2009, 133 patients with lung metastasis...

journal_title：Current medical research and opinion

authors： Liu XH,Man YN,Cao R,Liu C,Wu XZ

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The primary objective of the study was to compare the percentage of men with mean serum total T (C(ave(0-24))) within normal range during the 24-h pharmacokinetic (PK) sampling period on Days 14 and 15. METHODS:Treatment with a new testosterone (T) buccal system, (Striant), 30 mg twice daily was compared to ...

journal_title：Current medical research and opinion

authors： Dobs AS,Matsumoto AM,Wang C,Kipnes MS

更新日期：2004-05-01 00:00:00

abstract：:The efficacy and side-effect profiles of two formulations of indomethacin were compared in a multi-centre, double-blind, crossover study in 77 patients with osteoarthritis. Patients were allocated at random to receive 75 mg indomethacin per day either as 1 controlled-release tablet at night or as 1 immediate-release c...

journal_title：Current medical research and opinion

authors： Bacon P,Luqmani RA,Bossingham DH,Daymond TJ,Grahame R,West J,Hazleman BL,Adebajo AO,Hughes GR,Abdullah M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Benefits from interferon beta (IFNbeta treatment in patients with multiple sclerosis are affected by many factors, including sustained clinical efficacy, acceptable tolerability, adherence to therapy, and the development of neutralizing antibodies (NAbs). The Prospective and Retrospective Long-Term Observatio...

journal_title：Current medical research and opinion

authors： Minagara A,Murray TJ,PROOF Study Investigators.

更新日期：2008-04-01 00:00:00

abstract：:As the emergence of cardiovascular disease (CVD) is linked to modifiable lifestyle and physiological factors, it is increasingly important to concentrate on preventative strategies. For preventative measures to be beneficial it is necessary to clearly identify patients at risk--given that multiple risk factors often c...

journal_title：Current medical research and opinion

authors： De Backer G

更新日期：2007-11-01 00:00:00

abstract：:Poor nutritional status may impair well being indirectly as a consequence of increased morbidity and decline in functional status. The aim of this study was to examine the independent effect of body mass index on the well being of older people. Thirty one hospital-based patients over 65 years of age were studied. Well...

journal_title：Current medical research and opinion

authors： Balcombe NR,Ferry PG,Saweirs WM

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the efficacy and safety of doses of fentanyl buccal tablet (FBT) proportional to doses of opioids used for background analgesia versus dose titration starting with the minimal dose for the management of breakthrough cancer pain (BTcP). METHODS:A total of 82 cancer patien...

journal_title：Current medical research and opinion

authors： Mercadante S,Gatti A,Porzio G,Lo Presti C,Aielli F,Adile C,Casuccio A

更新日期：2012-06-01 00:00:00

abstract：:Quetiapine fumarate is a novel dibenzothiazepine antipsychotic developed by Zeneca. It is marketed under the trade name 'Seroquel'. Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia. The initial hope of investigators was that quetiapine would have antipsychotic potential and that ...

journal_title：Current medical research and opinion

authors： Green B

更新日期：1999-01-01 00:00:00

abstract：:Forty-two patients with a radiologically confirmed diagnosis of chronic pyelonephritis were treated with 1 g carindacillin every 6 hours over a period of 6 weeks. An underlying urological disease was present in 84% of the 38 patients for whom sufficient data were available for evaluation. The results of carindacillin ...

journal_title：Current medical research and opinion

authors： Michiels HG,Debruyne FM,Moonen WA

更新日期：1978-01-01 00:00:00

abstract：:In a multi-centre study, the antidepressant efficacy and incidence of on-therapy events of trazodone (100 to 400 mg daily) and mianserin (30 to 120 mg daily) was compared using a double-blind pre-determined randomized parallel group design in depressed patients unresponsive to placebo after a 7-day screening period. O...

journal_title：Current medical research and opinion

authors： Bennie EH,Khan MC,Tyrer SP,Siddiqui U,Ankier SI

更新日期：1984-01-01 00:00:00

abstract：:Objective: This economic evaluation aims to provide a preliminary assessment of the cost-effectiveness of radiofrequency ablation (RFA) compared with argon plasma coagulation (APC) when used to treat APC-refractory gastric antral vascular ectasia (GAVE) in symptomatic patients.Methods: A Markov model was constructed t...

journal_title：Current medical research and opinion

authors： Magee C,Graham D,Leonard C,McMaster J,Davies H,Skotchko M,Lovat L,Murray C,Mealing S,Smart H,Haidry R

更新日期：2020-06-01 00:00:00

abstract：:Filgrastim prophylaxis, both primary and secondary, was rapidly incorporated into clinical practice in the 1990s. When pegfilgrastim became available in 2002, it quickly replaced filgrastim as the colony-stimulating factor (CSF) of choice for prophylaxis. Use of prophylaxis increased markedly in the first decade of th...

journal_title：Current medical research and opinion

authors： Edelsberg J,Weycker D,Bensink M,Bowers C,Lyman GH

更新日期：2020-03-01 00:00:00