Abstract:
:The mutagenicities of 2-aminodipyrido [1,2-a:3',2'-d] imidazole (Glu-P-2, a mutagen obtained from pyrolysate of glutamic acid) and six methyl substituted derivatives of Glu-P-2 were tested with Salmonella typhimurium TA98 and TA100 with S-9 mix. Glu-P-1 (6-Me-Glu-P-2) was the strongest mutagen to TA98 and TA100. 3-Me-Glu-P-2 was weakest. The presence of a methyl group, and its position were shown to affect the mutagenicity significantly.
journal_name
Carcinogenesisjournal_title
Carcinogenesisauthors
Takeda K,Shudo K,Okamoto T,Nagao M,Wakabayashi K,Sugimura Tdoi
10.1093/carcin/1.11.889keywords:
subject
Has Abstractpub_date
1980-01-01 00:00:00pages
889-92issue
11eissn
0143-3334issn
1460-2180journal_volume
1pub_type
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