Identification of a Free Non-tryptophan Fluorophore in Water-soluble Fraction of Human Brunescent Cataractous Lens Nucleus.

abstract：:Surgically resected subretinal proliferative tissue (SRP) in proliferative vitreoretinopathy was examined by morphological and immunohistochemical methods. Membranous and strand-like SRPs were observed. Membranous SRP (4 cases) consisted of retinal pigment epithelial cells (RPEs) and a thin layer of extracellular mate...

journal_title：Japanese journal of ophthalmology

authors： Okada M,Ogino N,Matsumura M,Honda Y,Nagai Y

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To clarify the neuronal mechanism for the square-wave jerks (SWJs). METHODS:A 66-year-old man presented with oscillatory eye movements. He showed horizontal nystagmus in rightward gaze and SWJs during fixation at straight ahead. We recorded his eye movements with search coil methods and quantitatively analyzed...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Kase M,Hashimoto M,Ohtsuka K

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS:The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A...

journal_title：Japanese journal of ophthalmology

authors： Hatsukawa Y,Ueki N,Yamagishi T,Kitajima H

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:To investigate the predictive factors of polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy (PCV). METHODS:Sixty-nine eyes (69 patients) with treatment-naïve PCV received an initial series of 3-monthly intravitreal ranibizumab injections, followed by as-needed inje...

journal_title：Japanese journal of ophthalmology

authors： Cho HJ,Han SY,Kim HS,Lee TG,Kim JW

更新日期：2015-01-01 00:00:00

abstract：:The effects of three sulfhydryl agents on the cytoskeletal systems of cultured human trabecular cells were examined by the immunofluorescence method. Incubation with iodoacetamide or N-ethyl maleimide (10(-6) M, 10(-5) M, and 10(-4) M) caused a marked alteration on the actin and microtubule organization, but had littl...

journal_title：Japanese journal of ophthalmology

authors： Iwamoto Y,Tamura M,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：:We investigated the ocular fundus of (NZWXBXSB) F1 mice, which are considered to be a good model for systemic lupus erythematosus (SLE) with antiphospholipid syndrome. The abnormal fundus findings were documented by fundus photography, and the chorioretinal lesions were studied histopathologically. The incidence of oc...

journal_title：Japanese journal of ophthalmology

authors： Nakamura A,Yokoyama T,Kodera S,Zhang D,Hirose S,Shirai T,Kanai A

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

journal_title：Japanese journal of ophthalmology

authors： Sakimoto T,Shoji J,Yamada A,Sawa M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:We present 6 cases of bacterial infection that developed after porous orbital implant surgery. CASES:Five patients with hydroxyapatite implants showed lid swelling, discharge, and suppurative granuloma 14 days to 3 years after surgery. The hydroxyapatite implants were removed 14 days to 41 months postoperat...

journal_title：Japanese journal of ophthalmology

authors： You JR,Seo JH,Kim YH,Choi WC

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:The aqueous humor (AH) contains numerous immunosuppressive molecules that contribute to the ocular immune privilege. Here, we mimic an inflammatory environment to analyze the inhibitory effects of the AH on lipopolysaccharide (LPS)-induced maturation of dendritic cells (DC). METHODS:Different concentrations of...

journal_title：Japanese journal of ophthalmology

authors： Wang HF,Liu JL,Jiang XL,Lu JM,Li XL,Song XJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b. CASE:A 73-year-old woman presented with a complaint of irritation due to a tumorous...

journal_title：Japanese journal of ophthalmology

authors： Kobayashi A,Yoshita T,Uchiyama K,Shirao Y,Kitagawa K,Fujisawa A,Tseng SC

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:To report three types of heterozygous mutations in the OPA1 gene in five patients from three families with autosomal dominant optic atrophy (ADOA, MIM#165500). METHODS:DNA was extracted from the leukocytes of the peripheral blood. For mtDNA, mutations were examined at positions 11778, 3460 and 14484. For the O...

journal_title：Japanese journal of ophthalmology

authors： Hamahata T,Fujimaki T,Fujiki K,Miyazaki A,Mizota A,Murakami A

更新日期：2012-01-01 00:00:00

abstract：:Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...

journal_title：Japanese journal of ophthalmology

authors： Constable I

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To evaluate the occurrence of hyperemia with, and efficacy of, bimatoprost 0.01 % for patients in Korea previously treated for open-angle glaucoma (OAG; including normal tension glaucoma) or ocular hypertension (OHT). METHODS:In this multicenter, observational study (Asia Pacific Patterns from Early Access of ...

journal_title：Japanese journal of ophthalmology

authors： Kook MS,Simonyi S,Sohn YH,Kim CY,Park KH

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to clarify the demographics, clinical features, and outcomes of Japanese patients with sebaceous carcinoma of the eyelid or conjunctiva. STUDY DESIGN:Retrospective study. METHODS:One hundred twenty-five patients with sebaceous carcinoma of the eyelid or conjunctiva diagnosed at Tokyo...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Tsubota K,Nemoto R,Ueda S,Umazume K,Usui Y,Matsumura H

更新日期：2020-09-01 00:00:00

abstract：:A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...

journal_title：Japanese journal of ophthalmology

authors： Kihara Y,Shimomura Y,Omoto T,Fukuda M

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

journal_title：Japanese journal of ophthalmology

authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To report on isolated central retinal artery occlusion (CRAO) as an initial presentation in two patients with undiagnosed paroxysmal nocturnal hemoglobinuria (PNH). METHODS:CRAO related to the aggravation of PNH was observed in 2 of 98 consecutive PNH patients for 10 years. Ocular and systemic manifestations w...

journal_title：Japanese journal of ophthalmology

authors： Yang HS,Park SH,Choi JR,Kim JG

更新日期：2013-09-01 00:00:00

abstract：:The motoneurons innervating the musculus levator palpebrae superioris (LPS) of the monkey, the cat and the rabbit were studied using horseradish peroxidase (HRP). Furthermore, LPS motoneurons of the cat and rabbit were studied by the double-labeling method using two fluorescent dyes as retrograde neuronal tracers. Aft...

journal_title：Japanese journal of ophthalmology

authors： Hiramoto D,Sekiya H,Kojima Y,Mukuno K,Ishikawa S

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To prospectively compare the scotopic pupil size between emmetropes and myopes using a Colvard pupillometer. METHODS:The pupil diameters of 55 normal subjects and 55 healthy myopic subjects were measured with the Colvard pupillometer in a low-light situation that simulated the level of light encountered while ...

journal_title：Japanese journal of ophthalmology

authors： Chaidaroon W,Juwattanasomran W

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:Changes in optic disc and peripapillary structures associated with optic nerve edema in idiopathic intracranial hypertension (IIH), can be evaluated with spectral domain optical coherence tomography (SD-OCT). We aimed to evaluate the association between increased cerebrospinal fluid (CSF) opening pressure and c...

journal_title：Japanese journal of ophthalmology

authors： Bingöl Kızıltunç P,Atilla H

更新日期：2021-01-09 00:00:00

abstract：:The finite element algorithm is presented for the determination of heat flow within the partially frozen cornea during cryotherapy. The latent heat involved in phase change was taken into account by virtue of the enthalpy defined as the integral of heat capacity with respect to temperature. The numerical method is use...

journal_title：Japanese journal of ophthalmology

authors： Słuzalec A Jr,Muskalski K

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To determine the efficacy of real-time PCR for the diagnosis and prognosis of varicella-zoster virus (VZV) keratitis. STUDY DESIGN:Retrospective case series. METHODS:Patients: 545 consecutive patients with keratitis were examined to quantify copy numbers of VZV DNA by real-time PCR. Association of copy number...

journal_title：Japanese journal of ophthalmology

authors： Inata K,Miyazaki D,Uotani R,Shimizu D,Miyake A,Shimizu Y,Inoue Y

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To study the effect of voxel size on the detection of lateral geniculate nucleus (LGN) activation during visual stimulation using functional magnetic resonance imaging (fMRI) at 1.5 T. METHODS:Ten normal subjects were scanned during visual stimulation with flashing goggles, four times, with four different voxe...

journal_title：Japanese journal of ophthalmology

authors： Miki A,Liu CS,Liu GT

更新日期：2004-11-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:We present the pathological findings at orbital exenteration in a patient with Wyburn-Mason syndrome who underwent transarterial embolization. CASE:A 31-year-old man with a 10-year history of gradual exacerbation of left exophthalmos and left cheek swelling was found to have facial and orbital arteriovenous...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Yanai H,Sugiu K,Tominaga S,Kimata Y

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN:Retrospective, observational, multicenter case-series study. METHODS:Patients' data were entered into a compute...

journal_title：Japanese journal of ophthalmology

authors： Okamoto Y,Morikawa S,Okamoto F,Inomoto N,Ishikawa H,Ueda T,Sakamoto T,Sugitani K,Oshika T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To survey the changes in indications for penetrating keratoplasty (PKP) and re-evaluate the risk factors for allograft rejection and graft failure. METHODS:We evaluated the records of 396 eyes of 335 patients who had undergone PKP at the Tokyo University Hospital between 1987 and 1997. Clinical results were an...

journal_title：Japanese journal of ophthalmology

authors： Inoue K,Amano S,Oshika T,Sawa M,Tsuru T

更新日期：2000-03-01 00:00:00

abstract：:We evaluated the clinical statistics of a total of 186 patients (101 men and 85 women) with Vogt-Koyanagi-Harada's disease seen in the Uveitis Survey Clinic of the Hokkaido University Hospital during the 18-year period from 1966 to 1983. The annual number of new cases showed some change. More new patients were seen in...

journal_title：Japanese journal of ophthalmology

authors： Ohno S,Minakawa R,Matsuda H

更新日期：1988-01-01 00:00:00

abstract：:The ocular penetration of two beta-adrenergic blockers, befunolol and timolol, was studied using albino and pigmented rabbits. A 1% ophthalmic solution of 14C-befunolol hydrochloride or 14C-timolol maleate was instilled in one eye of nonsedated rabbits, and the concentrations of radioactive material in the ocular tiss...

journal_title：Japanese journal of ophthalmology

authors： Araie M,Takase M,Sakai Y,Ishii Y,Yokoyama Y,Kitagawa M

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:A prospective study was conducted to compare the effectiveness, safety, and stability of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for correction of low to moderate myopia. METHODS:Forty-five patients with a manifest refraction (PRK, -4.54 +/- 0.80; LASIK, -4.82 +/- 1.10) from ...

journal_title：Japanese journal of ophthalmology

authors： Lee JB,Kim JS,Choe C,Seong GJ,Kim EK

更新日期：2001-09-01 00:00:00