Neurotensin stimulates Cl(-) secretion in human colonic mucosa In vitro: role of adenosine.

abstract：:We studied the influence of morphine on intestinal secretion induced by three different secretogogues in an attempt to elucidate the mechanism for its antisecretory activity. In rabbit ileal mucosa in vitro morphine (10(-4) M) did not influence the electrical response to the subsequent administration of prostaglandin ...

journal_title：Gastroenterology

authors： McKay JS,Linaker BD,Higgs NB,Turnberg LA

更新日期：1982-02-01 00:00:00

abstract：:Eleven infants born to mothers with acute hepatitis B during the third trimester of pregnancy who were hepatitis B surface antigen-positive at delivery were treated with hepatitis B immune globulin within 24-48 h of birth. Five infants received one dose of hepatitis B immune globulin and 6 infants received a second do...

journal_title：Gastroenterology

authors： Tong MJ,Nair PV,Thursby M,Schweitzer IL

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND & AIMS:Rats fed ethanol at a constant rate through a permanent intragastric cannula have a regular fluctuation in blood alcohol level (BAL) and urine alcohol level (UAL). The level of ethanol peaks every 6-10 days. The question is how the liver differs at the peaks and troughs of the UAL cycle. Hypoxic injur...

journal_title：Gastroenterology

authors： Bardag-Gorce F,French BA,Li J,Riley NE,Yuan QX,Valinluck V,Fu P,Ingelman-Sundberg M,Yoon S,French SW

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND & AIMS:It is unclear whether patients with diabetes are at an increased risk of developing acute liver failure (ALF). We performed a large cohort study to examine the occurrence of ALF by using the databases of the Department of Veterans Affairs. METHODS:We identified all patients with a hospital discharge ...

journal_title：Gastroenterology

authors： El-Serag HB,Everhart JE

更新日期：2002-06-01 00:00:00

abstract：:We have recently demonstrated that release of oxygen-derived free radicals by activated hepatic macrophages may be involved in the pathogenesis of a rat model of liver injury induced by Corynebacterium parvum and endotoxin. In the present study we have compared the respiratory burst activity of isolated normal rat Kup...

journal_title：Gastroenterology

authors： Arthur MJ,Kowalski-Saunders P,Wright R

更新日期：1986-07-01 00:00:00

abstract：:The growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days. Except for one tumor that shrank on follow-up, the doubling time ranged from 29 to 398 days, with...

journal_title：Gastroenterology

authors： Sheu JC,Sung JL,Chen DS,Yang PM,Lai MY,Lee CS,Hsu HC,Chuang CN,Yang PC,Wang TH

更新日期：1985-08-01 00:00:00

abstract：:This study was undertaken to try to solve the controversy about the influence of gastrointestinal contents on the genesis of bowel sounds, and to probe the respective importance of the various abdominal viscera. Eleven healthy volunteers were intubated by mouth with a multiple-lumen tube. Bowel sounds were recorded fo...

journal_title：Gastroenterology

authors： Politzer JP,Devroede G,Vasseur C,Gerard J,Thibault R

更新日期：1976-08-01 00:00:00

abstract：:Serum gastrin and gastric endocrine cell numerical densities were examined in 22 patients with long-standing Zollinger-Ellison syndrome who were receiving either ranitidine, omeprazole, or other antisecretory drugs (SMS 201-995 or pirenzepine with or without ranitidine) for long periods of time. Fifteen patients had i...

journal_title：Gastroenterology

authors： Lehy T,Mignon M,Cadiot G,Elouaer-Blanc L,Ruszniewski P,Lewin MJ,Bonfils S

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND & AIMS:Induction of heat-shock protein 72 is associated with enhanced tolerance to subsequent nonthermal stresses. This study evaluated whether induction of heat-shock protein 72 protects against intestinal ischemia/reperfusion injury. METHODS:Groups of nonheated and heated rats underwent sham operation, 30...

journal_title：Gastroenterology

authors： Stojadinovic A,Kiang J,Smallridge R,Galloway R,Shea-Donohue T

更新日期：1995-08-01 00:00:00

abstract：:In the search for novel therapeutic approaches to treat patients with colorectal carcinoma, anticancer vaccination holds promise. A large body of preclinical and clinical evidence has demonstrated that the immune system can be polarized against malignant cells by means of several active specific immunotherapy strategi...

journal_title：Gastroenterology

authors： Mocellin S,Rossi CR,Lise M,Nitti D

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND & AIMS:Ground-glass (GG) inclusions within hepatocytes are an important histopathologic marker of chronic hepatitis B virus (HBV) infection but may also be seen in Lafora's disease (myoclonus epilepsy), cyanamide alcohol aversion therapy, and type IV glycogenosis. We have noted a recent increased incidence o...

journal_title：Gastroenterology

authors： Lefkowitch JH,Lobritto SJ,Brown RS Jr,Emond JC,Schilsky ML,Rosenthal LA,George DM,Cairo MS

更新日期：2006-09-01 00:00:00

abstract：:Incidence of intrahepatic arteriovenous fistula after needle biopsy of the liver, percutaneous transhepatic cholangiography, and transhepatic catheterization of an intrahepatic bile duct or portal vein, was determined by studying the hepatic arteriograms obtained within 1 month of the transhepatic procedure. An arteri...

journal_title：Gastroenterology

authors： Okuda K,Musha H,Nakajima Y,Takayasu K,Suzuki Y,Morita M,Yamasaki T

更新日期：1978-06-01 00:00:00

abstract：:Previous epidemiologic studies have suggested a weak association between oral contraceptive use and Crohn's disease, specifically Crohn's colitis. To measure a possible etiologic association, 51 women with Crohn's disease who were 18-50 yr old were studied and compared with peer-nominated age- and sex-matched controls...

journal_title：Gastroenterology

authors： Lashner BA,Kane SV,Hanauer SB

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Malnutrition is common in alcoholic cirrhosis. Bedside nutritional assessment techniques may be unreliable in patients with chronic liver disease. The aim of this study was to quantify changes in body composition and compare methods for measuring body composition in alcoholic cirrhosis. METHODS:Thirty-eight...

journal_title：Gastroenterology

authors： Prijatmoko D,Strauss BJ,Lambert JR,Sievert W,Stroud DB,Wahlqvist ML,Katz B,Colman J,Jones P,Korman MG

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND & AIMS:Dihydroxy bile acids induce a bicarbonate-rich hypercholeresis when secreted into canalicular bile in unconjugated form; the mechanism is cholehepatic shunting. The aim of this study was to identify a xenobiotic that induces hypercholeresis by a similar mechanism. METHODS:Five organic acids (sulindac...

journal_title：Gastroenterology

authors： Bolder U,Trang NV,Hagey LR,Schteingart CD,Ton-Nu HT,Cerrè C,Elferink RP,Hofmann AF

更新日期：1999-10-01 00:00:00

abstract：:Individuals who deny alcohol consumption may develop liver injury that histologically resembles the liver injury found in alcoholic patients. To determine whether any clinical or histologic features distinguish alcoholic and nonalcoholic subjects with "alcohollike" liver injury, the clinical records and liver biopsy s...

journal_title：Gastroenterology

authors： Diehl AM,Goodman Z,Ishak KG

更新日期：1988-10-01 00:00:00

abstract：:We tested methyl tertiary butyl ether both in vitro and in vivo to evaluate its efficacy as a potential cholesterol gallstone solvent for direct instillation into the human gallbladder or bile duct. Like diethyl ether, methyl tertiary butyl ether is an aliphatic ether with an excellent cholesterol-solubilizing capacit...

journal_title：Gastroenterology

authors： Allen MJ,Borody TJ,Bugliosi TF,May GR,LaRusso NF,Thistle JL

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND & AIMS:Infliximab is effective in closing fistulas in patients with Crohn's disease. We examined the effect of infliximab maintenance treatment on hospitalizations, surgeries, and procedures in patients with fistulizing Crohn's disease enrolled in the ACCENT II study. METHODS:After 5 mg/kg infliximab at wee...

journal_title：Gastroenterology

authors： Lichtenstein GR,Yan S,Bala M,Blank M,Sands BE

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with cirrhosis are characterized by a reduced splanchnic vascular resistance and a hyporeactivity to adrenergic vasoconstrictors. So far, their adrenergic splanchnic vascular responsiveness has not been evaluated in vitro. We compared responses to alpha1- and beta2-adrenoceptor stimulation of...

journal_title：Gastroenterology

authors： Heller J,Schepke M,Gehnen N,Molderings GJ,Müller A,Erhard J,Spengler U,Sauerbruch T

更新日期：1999-02-01 00:00:00

abstract：:Antral ulcers were produced in unanesthetized rats in 3 hr by simultaneous intravenous administration of acetylsalicylic acid (ASA) and gastric perfusion with 0.15 M HCl. Intravenous infusion of ASA alone or gastric perfusion with HCl alone produced no antral ulcers. Plasma salicylate levels ranged from 250 to 350 mic...

journal_title：Gastroenterology

authors： Kauffman GL Jr,Grossman MI

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND & AIMS:T helper (Th) 17 cells that express the retinoid-related orphan receptor (ROR) γt contribute to the development of colitis in mice, yet are found in normal and inflamed intestine. We investigated their development and functions in intestines of mice. METHODS:We analyzed intestinal Th17 cells in healt...

journal_title：Gastroenterology

authors： Ono Y,Kanai T,Sujino T,Nemoto Y,Kanai Y,Mikami Y,Hayashi A,Matsumoto A,Takaishi H,Ogata H,Matsuoka K,Hisamatsu T,Watanabe M,Hibi T

更新日期：2012-11-01 00:00:00

abstract：:We are reporting a patient with acute leptospirosis whose creatinine phosphokinase was markedly elevated secondary to an associated myositis. In patients presenting with acute hepatitis, an elevated creatinine phosphokinase should suggest the diagnosis of leptospirosis. Our patient's course of illness was made unusual...

journal_title：Gastroenterology

authors： Farkas PS,Knapp AB,Lieberman H,Guttman I,Mayan S,Bloom AA

更新日期：1981-03-01 00:00:00

abstract：:The conventional method of ascitic fluid culture detects bacteria in only 42%-65% of patients who have neutrocytic ascites and suspected spontaneous bacterial peritonitis. In this study ascitic fluid was cultured by the conventional method as well as by a new method consisting of bedside inoculation of blood culture b...

journal_title：Gastroenterology

authors： Runyon BA,Canawati HN,Akriviadis EA

更新日期：1988-11-01 00:00:00

abstract：:We have analyzed the frequency of chronicity and its distribution according to epidemiologic background following acute non-A, non-B hepatitis. Eighteen of 45 cases (40%) developed chronic liver disease. The incidence of chronicity was significantly higher following transfusion and among drug addicts (54% and 58%) tha...

journal_title：Gastroenterology

authors： Rakela J,Redeker AG

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND & AIMS:Two percent to 4% of all cases of colorectal cancer (CRC) are associated with Lynch syndrome. Dominant clustering of CRC (non-Lynch syndrome) accounts for 1%-3% of the cases. Because carcinogenesis is accelerated in Lynch syndrome, an intensive colonoscopic surveillance program has been recommended si...

journal_title：Gastroenterology

authors： Vasen HF,Abdirahman M,Brohet R,Langers AM,Kleibeuker JH,van Kouwen M,Koornstra JJ,Boot H,Cats A,Dekker E,Sanduleanu S,Poley JW,Hardwick JC,de Vos Tot Nederveen Cappel WH,van der Meulen-de Jong AE,Tan TG,Jacobs MA,Mohame

更新日期：2010-06-01 00:00:00

abstract：:The short-term effects of rat pancreatic duct obstruction were evaluated and compared with those recently reported to follow obstruction of the rabbit pancreatic duct. In both species pancreatic edema and hyperamylasemia are noted, and the lysosomal hydrolase cathepsin B is redistributed from the lysosome-enriched to ...

journal_title：Gastroenterology

authors： Ohshio G,Saluja A,Steer ML

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND & AIMS:Human primary liver cancer is classified into biologically distinct subgroups based on cellular origin. Liver cancer stem cells (CSCs) have been recently described. We investigated the ability of distinct lineages of hepatic cells to become liver CSCs and the phenotypic and genetic heterogeneity of pr...

journal_title：Gastroenterology

authors： Holczbauer Á,Factor VM,Andersen JB,Marquardt JU,Kleiner DE,Raggi C,Kitade M,Seo D,Akita H,Durkin ME,Thorgeirsson SS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND & AIMS:In patients with chronic Helicobacter pylori (H pylori) infection, parietal and chief cell atrophy in the gastric corpus, a process known as spasmolytic polypeptide-expressing metaplasia (SPEM), increases the risk for progression to cancer. The relation between H pylori and these metaplastic changes i...

journal_title：Gastroenterology

authors： Sáenz JB,Vargas N,Mills JC

更新日期：2019-01-01 00:00:00

abstract：:Endogenous pancreatic prostaglandin production in control and obstructive jaundice was investigated using isolated and perfused dog pancreas. In both groups, spontaneous production of prostaglandin E2 and prostaglandin I2 was recorded, and the levels did not change in both groups. The production of both prostaglandins...

journal_title：Gastroenterology

authors： Kuroda T,Kajikawa S,Hanazaki K,Horigome N,Sodeyama H,Horiuchi A,Iwatsuki K,Chiba S,Homma T,Iida F

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND & AIMS:Patients affected by familial adenomatous polyposis (FAP) are at increased risk of developing duodenal adenomas. In this study, cell proliferation of duodenal mucosa was analyzed to detect kinetic abnormalities related to cancer risk. METHODS:Duodenal biopsy specimens were collected in three groups o...

journal_title：Gastroenterology

authors： Santucci R,Volpe L,Zannoni U,Paganelli GM,Poggi B,Calabrese C,Biasco G

更新日期：1997-10-01 00:00:00