Characteristics of cold-sensitive mutants of Escherichia coli K-12 defective in deoxyribonucleic acid replication.

Abstract:

:Four cold-sensitive mutants of Escherichia coli have been isolated which show a reduced ability to synthesize deoxyribonucleic acid at low temperature. The mutants also have a reduced ability to incorporate nucleoside triphosphates into deoxyribonucleic acid at low temperature in cell preparations made permeable with toluene. All four mutations are located at or near the dnaA locus on the E. coli genetic map. They are recessive to the wild-type allele and two of them can be integratively suppressed by F episomes.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Wehr CT,Waskell L,Glaser DA

doi

10.1128/JB.121.1.99-107.1975

keywords:

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

99-107

issue

1

eissn

0021-9193

issn

1098-5530

journal_volume

121

pub_type

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