Abstract：
:During injection of artificial endolymph into scala media of the guinea pig, fluid pressure was simultaneously measured in endolymph and perilymph with micropipettes. Pressure differences in the order of 10 Pa could reproducibly be measured upon injection of 2-4 microl of artificial endolymph with a rate of 50 nl/s. Injection of larger volumes damaged the endolymphatic system. From the results, values were derived for the compliances of the membranes surrounding scala media and the vestibular part of the endolymphatic system. The shape of the pressure-time curve during and between repetitive injections of fluid could well be described with a two-component model for the endolymphatic system, consisting of two compartments with compliant walls, connected through a flow resistance. With this model, a larger compliance was found for the second compartment (vestibular part of endolymphatic system) than for the first compartment, into which fluid was injected (scala media).
journal_name
Hear Resjournal_title
Hearing researchauthors
Wit HP,Warmerdam TJ,Albers FWdoi
10.1016/s0378-5955(00)00078-2keywords:
subject
Has Abstractpub_date
2000-07-01 00:00:00pages
82-90issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(00)00078-2journal_volume
145pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:The central nucleus of the inferior colliculus (CNIC) contains different types of neurons and is a source of ascending projection to the medial geniculate body (MGB), commissural projection to the contralateral IC, direct descending projection to the cochlea nucleus (CN) and indirect projection to the CN via the super...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2006.04.004
更新日期：2006-08-01 00:00:00
abstract：:Functional magnetic resonance imaging is a noninvasive and nonradioactive method for the detection of focal brain activity. In the present study the auditory cortex was investigated in nine normal subjects who were binaurally stimulated using pulsed sine tones of 500 Hz and 4000 Hz. The BOLD (blood oxygenation level d...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00139-7
更新日期：1998-12-01 00:00:00
abstract：:Blind cave fish employ superficial neuromasts to detect currents [Baker, C.F. and J.C. Montgomery, J. Comp. Physiol. A 184 (1999) 519-527]. Briefly exposing fish to calcium-free water significantly reduces the ability of the fish to perform rheotaxis (i.e., to orient properly in currents). Spontaneous recovery to cont...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(02)00705-0
更新日期：2002-12-01 00:00:00
abstract：:The mechanisms underlying the ototoxicity of ethacrynic acid (EA) are not fully understood. Previous studies have focused on morphologic and enzymatic changes in the stria vascularis. The current experiment shows that one of the earliest effects of EA is ischemia, resulting from impaired blood flow in vessels supplyin...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(02)00585-3
更新日期：2002-11-01 00:00:00
abstract：:Many hearing-impaired listeners struggle to localize sounds due to poor availability of binaural cues. Listeners with a cochlear implant and a contralateral hearing aid - so-called bimodal listeners - are amongst the worst performers, as both interaural time and level differences are poorly transmitted. We present a n...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.03.007
更新日期：2018-06-01 00:00:00
abstract：:A mathematical model of the evolution of statoconia in statocysts of freshwater snails based on the analysis of experimental data [Wiederhold et al., 1990; Pedrozo et al., 1996; Gao et al., 1997; Gao and Wiederhold, 1997; Wiederhold et al., 1999] is proposed. The growth of statoconia is considered as the process of so...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00185-4
更新日期：2001-04-01 00:00:00
abstract：:Fluorescent tags and fluorophore-conjugated molecular probes have been extensively employed in histological studies to demonstrate nanoparticle distribution in inner ear cell populations. However, autofluorescence that exists in the rodent cochleae disturbs visualization of the fluorescent tags and fluorophore labelin...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2010.07.006
更新日期：2010-10-01 00:00:00
abstract：:This study was performed to elucidate the contribution of the stapedial artery (SA)--which has been considered to be independent of the vertebrobasilar system--to blood flow in the ear by observing ear blood flow in Sprague-Dawley rats. A laser-Doppler (LD) probe was positioned on the bony wall of the cochlear basal t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00310-1
更新日期：2003-12-01 00:00:00
abstract：:The latency of the N1 component of tone burst evoked compound action potentials was examined in chinchilla following acute pure-tone trauma. At and below the trauma frequency (4 kHz) the N1 latency at threshold generally increased, while above the trauma frequency it decreased; tonotopically paralleling pitch shifts o...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(83)90047-3
更新日期：1983-07-01 00:00:00
abstract：:It is known that adrenocorticotrophic hormone (ACTH)-derived peptides, the so-called melanocortins, can reduce cisplatin-induced neurotoxicity. Recently, our group has found that cisplatin-induced ototoxicity can also be reduced or prevented by treatment with the synthetic melanocortin-like peptide, ORG 2766 (Hamers e...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00194-4
更新日期：1999-02-01 00:00:00
abstract：:Auditory brainstem responses (ABR) from ten normal (3 males, 7 females) and ten environmentally sound deprived CBA/J mice (6 males, 4 females) were elicited by 30 dB HL click stimuli delivered via specially constructed, matched insert earphones. The mice were tested at 44-49 days of age under chloral hydrate sedation ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(83)90092-8
更新日期：1983-06-01 00:00:00
abstract：:The incidence and severity of audiogenic seizures in kanamycin (KM)-treated rat pups, from a Wistar strain which is inherently seizure-resistant, was analyzed as a function of (a) postnatal age at the time of KM injection (i.p.) and (b) KM dosage. The vigor of the pinna reflex response on postnatal day (PND) 28 was co...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(88)90142-6
更新日期：1988-01-01 00:00:00
abstract：:Glutamate plays a role in hair cell afferent transmission, but the receptors that mediate neurotransmission between outer hair cells (OHCs) and type II ganglion neurons are not well defined. A previous study using in situ hybridization showed that several kainate-type glutamate receptor (KAR) subunits are expressed in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.05.001
更新日期：2014-08-01 00:00:00
abstract：:This study explored the effects on speech intelligibility of across-formant differences in fundamental frequency (ΔF0) and F0 contour. Sentence-length speech analogues were presented dichotically (left = F1+F3; right = F2), either alone or-because competition usually reveals grouping cues most clearly-accompanied in t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.10.026
更新日期：2017-02-01 00:00:00
abstract：:It is known that the threshold of an acoustically induced middle-ear-muscle (MEM) reflex can be lowered by the simultaneous presentation of a second tone (facilitator), which is presented to the ipsilateral or contralateral ear at a level below the acoustic reflex threshold (ART) of the facilitator itself (Sesterhenn ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00039-7
更新日期：1997-06-01 00:00:00
abstract：:Effects of stimulus level on discrimination of one stimulation site from another were examined in 15 human subjects with Nucleus-22 cochlear implant systems. Bipolar stimulation was used in all cases with electrodes in the bipolar pair separated by 1.5 mm (center to center). Subjects were first tested at a medium loud...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00079-9
更新日期：1999-08-01 00:00:00
abstract：:Measurements were made of inner hair cell receptor potentials and basilar membrane motion in the 17-21 kHz region of the guinea pig cochlea. The latter were made using the Mossbauer technique. Isoamplitude curves at 0.9 mV d.c. receptor potential were compared with isovelocity curves at 0.04 mm/s and the corresponding...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(83)90019-9
更新日期：1983-04-01 00:00:00
abstract：:Electrical stimulation of the cochlea with a multiple-electrode array is best accomplished using pulsatile instead of continuous stimulation. The optimum shapes of electrical pulses for this purpose are still uncertain due to a lack of knowledge about their stimulation efficiency and requirements of the encoding strat...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90045-2
更新日期：1989-06-01 00:00:00
abstract：AIM:This study aimed to investigate the efficiency of Magnitude Squared Coherence (MSC) and Spectral F test (SFT) for the detection of auditory steady state responses (ASSR) obtained by amplitude-modulated noises. MATERIAL AND METHODS:Twenty individuals (12 women) without any history of neurological or audiological di...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.05.017
更新日期：2016-09-01 00:00:00
abstract：:Guinea pigs were exposed to pure tones of 10 kHz at intensities between 98 and 115 dB SPL for 5-30 min, to produce varying degrees of acoustic trauma. Changes in auditory thresholds were measured electrophysiologically, and the animals were immediately fixed for scanning electron microscopy. Correlation between morpho...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(96)00092-5
更新日期：1996-09-15 00:00:00
abstract：:Studies in several mammalian species have demonstrated that auditory cortical neurons respond strongly to single frequency-modulated (FM) sweeps, and that most responses are selective for sweep direction and/or rate. In the present study, we used extracellular recordings to examine how neurons in the auditory cortices...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00339-2
更新日期：2001-10-01 00:00:00
abstract：:We confirm the report of Mountain (Mountain, D.C. (1980): Science 210, 77-72) that stimulating the crossed olivocochlear bundle (COCB) can change the magnitude of the distortion product (f2-f1) in the ear-canal sound pressure. Our results are extended to include (2f1-f2) as well as (f2-f1) from anesthetized chinchilla...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(82)90052-1
更新日期：1982-02-01 00:00:00
abstract：:The purpose of this study is to: (1) examine the relative contributions of the 13 acoustically-responsive regions of the cerebral cortex to sound localization; (2) examine the laminar contributions to spatial localization behavior for each of the cortical areas identified to be critical for accurately determining the ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2007.01.013
更新日期：2007-07-01 00:00:00
abstract：:This study introduces and evaluates a method for measurement of the longitudinal spread of electrically evoked neural excitation in the cochlea, using the Neural Response Telemetry system (NRT) available with the Nucleus((R)) 24 cochlear implant system. The recently released version of the NRT software (version 3.0) e...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00096-0
更新日期：2003-05-01 00:00:00
abstract：:Auditory-nerve excitation by two response factors that can be in antiphase has been hypothesized by Kiang (1990) on the basis of non-linear interference in responses to tones (Kiang et al., 1969). The general conditions for antiphasic responses and the relevance of the hypothesis for other auditory stimuli are unknown...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/0378-5955(95)00154-7
更新日期：1995-10-01 00:00:00
abstract：:Gerbils are frequently used in auditory research; however, only limited information on the exact frequency representation in the cochlea is available. Therefore the place-frequency map of the gerbil was determined by iontophoretic application of horseradish peroxidase in physiologically characterized single auditory n...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00230-8
更新日期：1996-05-01 00:00:00
abstract：:High doses of sodium salicylate (SS) have long been known to induce temporary hearing loss and tinnitus, effects attributed to cochlear dysfunction. However, our recent publications reviewed here show that SS can induce profound, permanent, and unexpected changes in the cochlea and central nervous system. Prolonged tr...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2012.11.016
更新日期：2013-01-01 00:00:00
abstract：:The US Navy, through an Office of Naval Research (ONR) lead effort on Noise Induced Hearing Loss (NIHL), is investigating methods and techniques to mitigate hearing loss for the crews and warfighters. Hearing protection is a viable and increasingly popular method of reducing hearing exposure for many ship crew members...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2017.01.004
更新日期：2017-06-01 00:00:00
abstract：:For the purpose of creating a finite element model of the middle ear, the ossicles can be modelled as rigid bodies or as linear elastic materials. The general elasticity parameters used are usually measured on larger bones like the femur. In order to obtain a highly realistic model, the actual elastic modulus (Young's...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2009.10.001
更新日期：2010-05-01 00:00:00
abstract：:Proteomic analysis of cadaveric formalin-fixed, celloidin-embedded (FFCE) temporal bone tissue has the potential to provide new insights into inner ear disorders. We have developed a liquid chromatography-mass spectrometry (LC-MS) method for tissue sections embedded with celloidin. Q-TOF (Quadrupole-time of flight mas...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2010.08.003
更新日期：2010-12-01 00:00:00
