Abstract：
:The central nucleus of the inferior colliculus (CNIC) contains different types of neurons and is a source of ascending projection to the medial geniculate body (MGB), commissural projection to the contralateral IC, direct descending projection to the cochlea nucleus (CN) and indirect projection to the CN via the superior olivary complex (SOC). Using a retrograde tracing technique, we examined what kind of neurons and what percentage of neurons of each type recognized in the CNIC participated in the above-mentioned four projection pathways. We also examined whether the individual CNIC neurons send the collateral to the MGB, the contralateral IC, the CN and the SOC. In the present study, we demonstrated that the neurons participating in the four projections could be morphologically classified into two types of neurons with soma size variation. The percentages of neurons of each type differed among the four projection pathways. Using a double-labeling technique, we found very few double-labeled neurons, indicating the collateral projections to the ipsilateral MGB and the contralateral IC. There were no double-labeled neurons in the collateral projections between the other combinations of targets. Therefore, we conclude that the ascending projection, the commissural projection and the descending projection to these targets arise from separate populations of neurons.
journal_name
Hear Resjournal_title
Hearing researchauthors
Okoyama S,Ohbayashi M,Ito M,Harada Sdoi
10.1016/j.heares.2006.04.004subject
Has Abstractpub_date
2006-08-01 00:00:00pages
72-80issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(06)00124-9journal_volume
218pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:The effects of eliminating the olivocochlear bundle (OCB) on cochlear electromechanical properties were examined by measuring cochlear microphonics (CM) and distortion product otoacoustic emissions (DPOAEs) in chronically de-efferented chinchillas. The OCB fibers to the right ears were successfully sectioned in six ou...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00217-8
更新日期：2000-05-01 00:00:00
abstract：:Eighth nerve endings and neuronal types in the nucleus magnocellularis were analyzed in the red-eared turtle (Chrysemys scripta elegans). One group of turtles had horseradish peroxidase (HRP) injected into the surgically exposed inner ear. Following injection the animals survived for 3-5 days and then their 8th nerve ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(88)90156-6
更新日期：1988-06-01 00:00:00
abstract：:Echolocation offers a promising approach to improve the quality of life of people with blindness although little is known about the factors influencing object localisation using a 'searching' strategy. In this paper, we describe a series of experiments using sighted and blind human listeners and a 'virtual auditory sp...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2013.03.005
更新日期：2013-06-01 00:00:00
abstract：:Spectral analysis of electrical noise recorded from the round window (RW) of the cochlea is referred to as the ensemble spontaneous activity (ESA) of the cochlear nerve. The ESA is considered to represent the summed spontaneous activity of single fibers of the auditory nerve and changes in the spectral characteristics...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.02.006
更新日期：2004-06-01 00:00:00
abstract：:Older adults are often reported in the literature to have greater difficulty than younger adults understanding speech in noise [Helfer and Wilber (1988). J. Acoust. Soc. Am, 859-893]. The poorer performance of older adults has been attributed to a general deterioration of cognitive processing, deterioration of cochlea...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.09.001
更新日期：2014-11-01 00:00:00
abstract：:The ear of the goldfish (Carassius auratus) contains three otolithic endorgans: the saccule, lagena, and utricle. The saccule has an auditory function in most teleost fishes for whom data are available, and there is evidence that the lagena is also an auditory endorgan in the goldfish. This study was conducted to comp...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00207-5
更新日期：2000-03-01 00:00:00
abstract：UNLABELLED:While the positive benefits of pediatric cochlear implantation on language perception skills are now proven, the heterogeneity of outcomes remains high. The understanding of this heterogeneity and possible strategies to minimize it is of utmost importance. Our scope here is to test the effects of an auditory...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.05.003
更新日期：2016-07-01 00:00:00
abstract：:The present study aimed to investigate whether gap-prepulse inhibition (GPI) deficit in patients with tinnitus occurred in the N1-P2 complex of the cortical auditory evoked potential. Auditory late responses to the intense sound of the GPI paradigm were obtained from 16 patients with tinnitus and 18 age- and hearing l...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2017.03.003
更新日期：2017-05-01 00:00:00
abstract：:Wavelength-swept optical coherence tomography (OCT) was used to scan the structure of cadaveric chinchilla ears in three dimensions with high spatial resolution and measure the sound-induced displacements of the entire OCT-visible lateral surfaces of the ossicles in the lateral-to-medial direction. The simultaneous me...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.108056
更新日期：2020-10-01 00:00:00
abstract：:There is increasing evidence that humans and other nonhuman mammals are sensitive to the statistical structure of auditory input. Indeed, neural sensitivity to statistical regularities seems to be a fundamental biological property underlying auditory learning. In the case of speech, statistical regularities play a cru...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2013.08.018
更新日期：2014-02-01 00:00:00
abstract：:The responses of single units in the ventral cochlear nucleus of acute anesthetized guinea pigs were studied with continuous sinusoidal electrical stimuli presented through a multi-electrode implant in the scala tympani. Implants had two or four electrodes along the axis of the scala with 1 mm separations. Best freque...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(83)90108-9
更新日期：1983-11-01 00:00:00
abstract：:Tinnitus is most often initiated by modality specific otopathologic disturbances affecting peripheral and central auditory pathways. However, there is growing evidence indicating that the anatomical location generating tinnitus occurs at sites different from the initial pathology. Support for this notion is found in i...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/s0378-5955(02)00717-7
更新日期：2003-01-01 00:00:00
abstract：:Previous studies have shown a reduction of the ototoxicity of furosemide in chinchillas pretreated with organic acid transport inhibitors. The current studies were designed to investigate whether such a protective effect could be observed in chinchillas receiving ethacrynic acid. Chinchillas weighing 400-600 g were in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90142-c
更新日期：1990-06-01 00:00:00
abstract：:The voice is a rich source of information, which the human brain has evolved to decode and interpret. Empirical observations have shown that the human auditory system is especially sensitive to the human voice, and that activity within the voice-sensitive regions of the primary and secondary auditory cortex is modulat...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2015.07.003
更新日期：2015-10-01 00:00:00
abstract：:Most investigators place reflective beads on the basilar membrane to measure its vibration with optical methods. It is therefore important to find out if the beads faithfully follow the motion of the structures on which they are placed. Vibration of the beads on the basilar membrane and basilar membrane adjacent to th...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00200-1
更新日期：1998-02-01 00:00:00
abstract：:The number, size and distribution of myelinated nerve fibers were analyzed in the osseous spiral lamina (OSL) of young and old gerbils raised in a quiet environment. Because decreased endocochlear potentials (EPs) play a significant role in age-related hearing loss in the gerbil, we correlated morphometric and topogra...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00340-9
更新日期：2001-11-01 00:00:00
abstract：:DNA methylation and histone modifications such as methylation, acetylation, and phosphorylation, are two types of epigenetic modifications that alter gene expression. These additions to DNA regulatory elements or to the tails of histones can be inherited or can also occur de novo. Since epigenetic modifications can ha...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2019.01.007
更新日期：2019-05-01 00:00:00
abstract：:Although gap junctions occur in auditory and vestibular systems, their function is unclear. Here we present evidence for gap junctional communication in transmitting mechanosensory signals in a sea anemone model system. Hair bundles on anemone tentacles are vibration-sensitive mechanoreceptors that regulate discharge ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00047-2
更新日期：2000-06-01 00:00:00
abstract：:An analysis of the central projections of the ventral nucleus of the trapezoid body (VNTB) in the rat, a region of the superior olivary complex known for its neuronal heterogeneity, was made using two anterograde axonal tracers, [3H]leucine and biotinylated dextran amine (BDA). A mixture of these tracers was injected ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00198-0
更新日期：1996-04-01 00:00:00
abstract：:Primary afferent activity was recorded from the cochlear ganglion in chicken embryos (Gallus domesticus) at 19 days of incubation (E19). The ganglion was accessed via the recessus scala tympani and impaled with glass micropipettes. Frequency tuning curves were obtained using a computerized threshold tracking procedure...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)00172-m
更新日期：1995-02-01 00:00:00
abstract：:Spatial hearing skills are essential for children as they grow, learn and play. These skills provide critical cues for determining the locations of sources in the environment, and enable segregation of important sounds, such as speech, from background maskers or interferers. Spatial hearing depends on availability of ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2016.01.003
更新日期：2016-08-01 00:00:00
abstract：:This report describes a study that took advantage of the unique reactivity of the patas monkey (Erythrocebus patas) to dihydrostreptomycin-sulfate (DHSM) to investigate the effects of selective outer hair cell (OHC) lesions on psychophysical tuning curves (PTC). Four patas monkeys were trained using operant reinforcem...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90161-4
更新日期：1987-01-01 00:00:00
abstract：:Pairs of single units were recorded simultaneously from the same microelectrode in the medial geniculate body (MGB) of nitrous oxide anaesthetized cats. Crosscorrelation histograms of each spike train pairs were computed and distributed in five main classes, interpreted in terms of functional interaction between neigh...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90093-1
更新日期：1987-01-01 00:00:00
abstract：:The stimulus level and frequency dependence of the quadratic difference tone (QDT) measured as an otoacoustic emission in the ear canal has been investigated in the guinea pig and compared with simultaneously measured cubic difference tone (CDT) and with the round window electrical response. Acoustic QDT level tended ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(93)90154-s
更新日期：1993-11-01 00:00:00
abstract：:Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated eleme...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：:The molecular composition and three-dimensional organization of the extracellular matrix (ECM) was studied by immunofluorescent microscopy, transmission and scanning electron microscopy in three connective tissue structures of the cochlea: the spiral limbus, basilar membrane and spiral ligament. Type II collagen, fibr...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00219-6
更新日期：1999-03-01 00:00:00
abstract：:Glutamate is the neurotransmitter of the synapse between vestibular type I hair cells and the afferent nerve calyx. This calyx may also be involved in local feedback, which may modify sensory cell activity via N-methyl-D-aspartate (NMDA) receptors. Glycine is the co-agonist of glutamate in NMDA receptor activation. Bo...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00194-x
更新日期：2000-02-01 00:00:00
abstract：:A novel immunocytochemical method was used to determine whether the sound-damaged adult quail ear can repair its tectorial membrane (TM) and to compare the repair in quail to that in chicks. Birds were exposed to an octave band noise with a center frequency of 1.5 kHz at 116 dB SPL for 4 h. The chicks were grouped bas...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00051-5
更新日期：1995-06-01 00:00:00
abstract：OBJECTIVE:Molecular analysis using archival human inner ear specimens is challenging because of the anatomical complexity, long-term fixation, and decalcification. However, this method may provide great benefit for elucidation of otological diseases. Here, we extracted mRNA for RT-PCR from tissues dissected from archiv...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2013.04.008
更新日期：2013-08-01 00:00:00
abstract：:The influence of noise exposure on the endothelial transport system in the cochlea was investigated using cationic polyethyleneimine (PEI), since systemically administered PEI passes through the capillary endothelial cell and attaches to basal lamina (BL) anionic sites in the cochlea. Under general anesthesia, all gui...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00397-5
更新日期：2002-02-01 00:00:00
