Abstract：
:A mathematical model of the evolution of statoconia in statocysts of freshwater snails based on the analysis of experimental data [Wiederhold et al., 1990; Pedrozo et al., 1996; Gao et al., 1997; Gao and Wiederhold, 1997; Wiederhold et al., 1999] is proposed. The growth of statoconia is considered as the process of solution crystallization. The model proposed assumes that two main processes determine the evolution of statoconia in developing snails: the generation of new statoconia and the linear growth of statoconia sizes. The analytical solution of the model and qualitative comparison of theoretical results with the experimental data show: (1) there are at least three periods of statoconia evolution; (2) the generation of new statoconia mainly determines the first period of evolution when the shell diameter of snails D < 4 mm; (3) when D > 6 mm the size distribution of statoconia is determined by the growth of their sizes with a constant rate; (4) on the interval deltaD = 4-6 mm the transformation of size distribution with selective dissolution of statoconia takes place. The model agrees well with the experimental data and makes it possible to estimate some parameters of the statoconia kinetics. Additional experiments, which are necessary for further development of the model, and quantitative estimates of the mechanisms of statoconia evolution are formulated.
journal_name
Hear Resjournal_title
Hearing researchauthors
Kondrachuk AVdoi
10.1016/s0378-5955(00)00185-4keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
1-11issue
1-2eissn
0378-5955issn
1878-5891pii
S0378595500001854journal_volume
154pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:Age-related cochlear synaptopathy (CS) has been shown to occur in rodents with minimal noise exposure, and has been hypothesized to play a crucial role in age-related hearing declines in humans. Because CS affects mainly low-spontaneous rate auditory nerve fibers, differential electrophysiological measures such as the...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.108068
更新日期：2020-10-01 00:00:00
abstract：:In Menière's disease, the increase of extracellular potassium concentration in the perilymph is thought to play a key role in determining the progressive loss of cochlear hair cells. In this paper, we describe a serum-free culture preparation of hair cells from 5 day-old rat and report the release by the cochlea, in r...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90168-o
更新日期：1990-08-01 00:00:00
abstract：:A critical issue in large-scale gene expression analysis is the impact of sexually dimorphic genes, which may confound the results when sampling across sexes. Here, we assessed, for the first time, sex differences at the transcriptome level in the auditory brainstem. To this end, microarray experiments covering the wh...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2008.08.008
更新日期：2008-11-01 00:00:00
abstract：:We have studied the noradrenergic and serotonergic changes induced by white noise stimulation at 70, 90 or 110 dB SPL for 45 min, in cochlear nuclei, inferior colliculus (IC), primary auditory cortex (PAC) and as a comparison in locus coeruleus (LC) and raphe dorsalis using HPLC. Both noradrenergic and serotonergic pa...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00031-8
更新日期：1998-04-01 00:00:00
abstract：:Long-term experience enhances neural representation of temporal attributes of pitch in the brainstem and auditory cortex in favorable listening conditions. Herein we examine whether cortical pitch mechanisms shaped by language experience are more resilient to degradation in background noise, and exhibit greater binaur...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2017.09.006
更新日期：2017-11-01 00:00:00
abstract：:A series of organic acid transport inhibitors significantly reduced the endocochlear potential (EP) decline produced by furosemide in the chinchilla. Probenecid, sodium salicylate and penicillin G were much more effective than novobiocin, meclofenamate or diatrizoate. Inhibitors of organic base transport, choline and ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90037-2
更新日期：1987-01-01 00:00:00
abstract：:A field potential could be recorded in the deep layers of the superior colliculus (SCd) in the guinea pig following presentation of pure tone bursts at frequencies between 1 and 22 kHz, bursts of white noise, and clicks presented in the free field. The potentials evoked by these stimuli at different intensities had tw...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90118-3
更新日期：1987-12-01 00:00:00
abstract：:Fluorescent tags and fluorophore-conjugated molecular probes have been extensively employed in histological studies to demonstrate nanoparticle distribution in inner ear cell populations. However, autofluorescence that exists in the rodent cochleae disturbs visualization of the fluorescent tags and fluorophore labelin...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2010.07.006
更新日期：2010-10-01 00:00:00
abstract：:Severe damage to the organ of Corti leads to degeneration of the spiral ganglion cells (SGCs) which form the auditory nerve. This degeneration starts at the level of synaptic connection of the peripheral processes (PPs) of SGCs with the cochlear hair cells. It is generally thought that from this point SGC degeneration...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.107928
更新日期：2020-05-01 00:00:00
abstract：:Can the vestibular periphery of warm-blooded vertebrates recover functionally from severe sensory hair cell loss? Recent findings in birds suggest a mechanism for recovery but in fact no direct functional evidence has been reported. We produced vestibular hair cell lesions using the ototoxic agent streptomycin sulfate...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(92)90184-o
更新日期：1992-10-01 00:00:00
abstract：:Carboplatin preferentially destroys inner hair cells (IHCs) in the chinchilla inner ear, while retaining a near-normal outer hair cell (OHC) population. The present study investigated the functional consequences of IHC loss on the compound action potential (CAP), inferior colliculus potential (ICP) and auditory cortex...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00171-9
更新日期：2000-01-01 00:00:00
abstract：:Voice emotion is a fundamental component of human social interaction and social development. Unfortunately, cochlear implant users are often forced to interface with highly degraded prosodic cues as a result of device constraints in extraction, processing, and transmission. As such, individuals with cochlear implants ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2017.01.006
更新日期：2017-09-01 00:00:00
abstract：:There is evidence that pentobarbital, a commonly used anesthetic, can affect neuronal activity, but its effects on particular neurons of the dorsal cochlear nucleus (DCN) are not well known. Bursting (complex spiking) spontaneous activity has been observed in the DCN in brain slice preparations and in recordings from ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00188-x
更新日期：2000-11-01 00:00:00
abstract：:Human behavioral thresholds for trains of biphasic pulses applied to a single channel of Nucleus CI24 and LAURA cochlear implants were measured as a function of inter-phase gap (IPG). Experiment 1 used bipolar stimulation, a 100-pps pulse rate, and a 400-ms stimulus duration. In one condition, the two phases of each p...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.03.021
更新日期：2005-07-01 00:00:00
abstract：:No adequate theory for the signal-transmission properties of the peripheral auditory system exists for any vertebrate ear. Because the mammalian ear seems to pose conceptual and technical problems that complicate the development of an adequate theory, it is worthwhile to investigate simpler ears. The ear of the alliga...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(85)90164-9
更新日期：1985-01-01 00:00:00
abstract：:The effects of genotype and diet on age-related hearing loss were evaluated using auditory brainstem response (ABR) thresholds and post-mortem cochlear histopathology in 5 inbred mouse strains, CBA/H-T6J (CH), DBA/2J (D2), C57BL/6J (B6), BALB/cByJ (BY) and WB/ReJ (WB), and their 10 F1 hybrid strains. The mice had been...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00107-f
更新日期：1995-08-01 00:00:00
abstract：:Two methods were used to extract frequency specific information from the gross d.c. cochlear potential, the summating potential (SP). The first approach was to derive SP tuning curves using a two-tone simultaneous masking procedure; the second to obtain SP iso-response functions. The influence of various parameter cha...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(84)90009-1
更新日期：1984-11-01 00:00:00
abstract：:Until recently the responses of the mechanosensitive hair cells of the cochlea have been inferred from their morphology, morphological relationships with other structures in the cochlea, and by indirect electrophysiological measurements. With the advent of techniques for making intracellular recordings from hair cells...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(86)90096-1
更新日期：1986-01-01 00:00:00
abstract：:This study is the continuation of the functional probing of the auditory periphery in the normal and jaundiced rat. Threshold tuning curves from normal rat auditory nerve fibers were comparable to those reported in other mammals. Life-long unconjugated hyperbilirubinemia does not appear to have a widespread, demonstra...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(91)90139-z
更新日期：1991-07-01 00:00:00
abstract：:A hyperpolarization-activated current (termed I[h]) is believed to provide a pacemaker depolarization in sinoatrial node cells and in some central and peripheral neurons. In the present study, we examined if such an inward cation current exists in primary auditory neurons using the whole-cell patch-clamp technique. A ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00078-6
更新日期：1997-08-01 00:00:00
abstract：:The influence of temporal cues on sequential stream segregation was investigated using five elderly hearing-impaired listeners. In experiment 1, an alternating pattern of A and B tones was used. Each tone was a harmonic complex with a 100-Hz fundamental, with one of three passbands (1250-2500, 1768-3636, or 2500-5000 ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.02.003
更新日期：2004-06-01 00:00:00
abstract：:Periodicity coding was studied in primary auditory cortex of the ketamine anesthetized cat by simultaneously recording with two electrodes from up to 6 neural units in response to one second long click trains presented once per 3 s. Trains with click rates of 1, 2, 4, 8, 16 and 32/s were used and the responses of the ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(91)90165-6
更新日期：1991-11-01 00:00:00
abstract：:The goal of the present paper is to relate the coding of amplitude modulation (AM) in the auditory pathway to the behavioral detection performance. To address this issue, the detectability of AM was estimated by modelling a single neuron located in the central nucleus of the inferior colliculus (IC). The computational...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00169-9
更新日期：1995-10-01 00:00:00
abstract：:Spike potentials were recorded from single, afferent fibres in the pigeon auditory nerve. Pure-tone stimuli were presented in quiet and in combination with wide band noise. Presented alone, tones produced tuned response areas; noise generally drove spike rate to well above the spontaneous rate measured in quiet. When ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90081-6
更新日期：1989-05-01 00:00:00
abstract：:Most previous reports of ototoxicity following exposure to several volatile organic solvents have restricted testing to the low- and mid-frequencies (2-20 kHz) of the hearing range in the rat (0.25-80 kHz). We report here that inhalation exposure to styrene, mixed xylene, toluene, and 1,1,2-trichloroethylene resulted ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)90005-1
更新日期：1994-10-01 00:00:00
abstract：:This article presents a comparison of Liouville-Green (LG) calculations and exact solutions of 2- and 3-dimensional cochlea models. The agreement is in general quite good. For certain choices of the model parameters, however, the 2- and 3-dimensional LG solutions show appreciable errors in the region just beyond the l...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(82)90071-5
更新日期：1982-10-01 00:00:00
abstract：:An analysis of the central projections of the ventral nucleus of the trapezoid body (VNTB) in the rat, a region of the superior olivary complex known for its neuronal heterogeneity, was made using two anterograde axonal tracers, [3H]leucine and biotinylated dextran amine (BDA). A mixture of these tracers was injected ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00198-0
更新日期：1996-04-01 00:00:00
abstract：:Glass microelectrodes were introduced into the stria vascularis (SV) to measure the DC potential profile of the SV in vivo from its apical as well as basal side. The K+ concentration gradient in the lateral cochlear wall was measured by means of double barrel K+-selective microelectrodes. A positive potential 10.4 +/-...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90077-3
更新日期：1987-01-01 00:00:00
abstract：:1. The sound pressure level required to produce a detectable gross action potential (N1) in the guinea pig was measured for a range of frequencies. The resulting electrocochleogram was compared with the click level require to produce a detectable N1. 2. Over most of the auditory range (1-30 kHz) the required click lev...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(81)90018-6
更新日期：1981-07-01 00:00:00
abstract：:The discharge properties of 735 single units located in the pars magnocellularis (M) of the medial division of the medial geniculate body (MGB) were studied in 23 nitrous oxide anesthetized cats in response to simple acoustic stimuli (clicks, noise and tone bursts). A systematic decrease of single unit characteristic ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90086-5
更新日期：1989-05-01 00:00:00
