The sensitive period and optimum dosage for induction of audiogenic seizure susceptibility by kanamycin in the Wistar rat.

abstract：:Inbred strain variants of the Cdh23 gene have been shown to influence the onset and progression of age-related hearing loss (AHL) in mice. In linkage backcrosses, the recessive Cdh23 allele (ahl) of the C57BL/6J strain, when homozygous, confers increased susceptibility to AHL, while the dominant allele (Ahl+) of the C...

journal_title：Hearing research

authors： Kane KL,Longo-Guess CM,Gagnon LH,Ding D,Salvi RJ,Johnson KR

更新日期：2012-01-01 00:00:00

abstract：:In the cochlea, outer hair cells (OHCs) generate the active cochlear mechanics whereas the supporting cells, such as Deiters' cells and Hensen's cells, may play a role in both the active and passive cochlear mechanics. The presence of receptors for adenosine triphosphate (ATP) on OHCs, Deiters' cells and Hensen's cell...

journal_title：Hearing research

authors： Chen C,Skellett RA,Fallon M,Bobbin RP

更新日期：1998-04-01 00:00:00

abstract：:Anatomically correct turtle utricle geometry was incorporated into two finite element models. The geometrically accurate model included appropriately shaped macular surface and otoconial layer, compact gel and column filament (or shear) layer thicknesses and thickness distributions. The first model included a shear la...

journal_title：Hearing research

authors： Davis JL,Grant JW

更新日期：2014-12-01 00:00:00

abstract：:Biomarkers in easy-to-access body fluid compartments, such as blood, are commonly used to assess health of various organ systems in clinical medicine. At present, no such biomarkers are available to inform on the health of the inner ear. Previously, we proposed the outer-hair-cell-specific protein prestin, as a possib...

journal_title：Hearing research

authors： Parham K,Sohal M,Petremann M,Romanet C,Broussy A,Tran Van Ba C,Dyhrfjeld-Johnsen J

更新日期：2019-01-01 00:00:00

abstract：:Action potentials recorded extracellularly from neurons within the caudal cochlear nuclei of developing cats exhibited distinctive temporal characteristics (i.e., rhythmic responses) in response to long-duration acoustic stimuli including both tone and noise bursts. Unlike the homogeneous response characteristics of a...

journal_title：Hearing research

authors： Walsh EJ,McGee J

更新日期：1988-11-01 00:00:00

abstract：:Auditory brainstem responses (ABR) from ten normal (3 males, 7 females) and ten environmentally sound deprived CBA/J mice (6 males, 4 females) were elicited by 30 dB HL click stimuli delivered via specially constructed, matched insert earphones. The mice were tested at 44-49 days of age under chloral hydrate sedation ...

journal_title：Hearing research

authors： Evans WJ,Webster DB,Cullen JK Jr

更新日期：1983-06-01 00:00:00

abstract：:Cortical auditory evoked potentials (CAEPs) have been successfully used to explore the effects of noise on speech processing at the cortical level in adults and children. The purpose of this study was to determine whether +15 dB signal-to-noise ratios (SNRs), often recommended for optimal speech perception in children...

journal_title：Hearing research

authors： Benítez-Barrera CR,Key AP,Ricketts TA,Tharpe AM

更新日期：2021-01-05 00:00:00

abstract：:Unlike the organ of Corti in mammals, the avian basilar papilla has no distinct populations of hair cells. Instead, there is a continuous change between the extreme forms (tall hair cells = THC, and short hair cells = SHC). The hair-cell innervation pattern is complicated, there being no simple gradient between THC (m...

journal_title：Hearing research

authors： Fischer FP

更新日期：1992-08-01 00:00:00

abstract：:To estimate the correlation between the cochlear lateral wall and endocochlear potential (EP), the EP was measured at different time intervals up to 3 weeks at cochlear focal lesions made in the guinea pig. Lesions were produced by a photochemical reaction between systemically administered Rose Bengal and green light ...

journal_title：Hearing research

authors： Wu R,Hoshino T,Nagura M

更新日期：1999-02-01 00:00:00

abstract：:In the developing inner ear, a naturally occurring programmed cell death of cochleovestibular ganglion (CVG) neurons as well as peripheral and central target-derived trophic effects on survival of embryonic CVG neurons are known. To further analyze these target derived trophic interactions, spiral ganglion explants ob...

journal_title：Hearing research

authors： Lefebvre PP,Weber T,Rigo JM,Staecker H,Moonen G,Van De Water TR

更新日期：1992-03-01 00:00:00

abstract：:The rather shallow growth of click-evoked otoacoustic emissions (CEOAE) with click intensity, namely <1 dB/dB, distinguishes genuine CEOAEs from stimulus artifacts, thereby providing the rationale for the popular 'derived nonlinear recording' method. However, other CEOAE nonlinearities regarding phase or envelope depe...

journal_title：Hearing research

authors： Carvalho S,Büki B,Bonfils P,Avan P

更新日期：2003-01-01 00:00:00

abstract：:The course, distribution and termination of single efferent fibers to the cochlea has been described in only a few animals and relatively few fibers have been studied with knowledge of their ipsilateral or contralateral origin. In order to examine the efferent fibers in the mouse, the anterograde tracer Phaseolus vulg...

journal_title：Hearing research

authors： Wilson JL,Henson MM,Henson OW Jr

更新日期：1991-09-01 00:00:00

abstract：:When auditory nerve function is lost due to surgical removal of bilateral acoustic tumors in cases of neurofibromatosis type 2, a sense of hearing may be restored by means of an auditory brainstem implant (ABI), which electrically stimulates the cochlear nucleus. Electrically evoked auditory brainstem responses record...

journal_title：Hearing research

authors： Waring MD,Ponton CW,Don M

更新日期：1999-04-01 00:00:00

abstract：:Strial marginal cells are known to take up and metabolize glucose as their main source of metabolic energy. The membrane transport mechanisms for glucose uptake into strial marginal cells, however, are largely unknown. Two types of glucose transporters in mammalian cells have been described, the facilitated glucose tr...

journal_title：Hearing research

authors： Takeuchi S,Ando M

更新日期：1997-12-01 00:00:00

abstract：:The properties of the ACh (acetylcholine) response in guinea pig outer hair cells (OHCs) are not well understood. It has been shown that the response to ACh involves the activation of a Ca2+ dependent K+ selective conductance (referred to as Ksub where sub stands for suberyldicholine). In the present study, we examine...

journal_title：Hearing research

authors： Nenov AP,Norris C,Bobbin RP

更新日期：1996-11-01 00:00:00

abstract：:The effects of endogenous and exogenous Ca(2+) buffers on Ca(2+) current kinetics have been investigated by patch clamp in hair cells mechanically isolated from frog semicircular canals. This preparation displays at least three different Ca(2+) channel types: transient currents flow through a drug-resistant channel ("...

journal_title：Hearing research

authors： Martini M,Rispoli G,Farinelli F,Fesce R,Rossi ML

更新日期：2004-09-01 00:00:00

abstract：:Spiral ganglion cell (SGC) degeneration following hair cell loss can be prevented by administration of exogenous neurotrophic factors. Many of these neurotrophic factors, in particular the neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), have been described to be involved in the develo...

journal_title：Hearing research

authors： Ramekers D,Versnel H,Grolman W,Klis SF

更新日期：2012-06-01 00:00:00

abstract：:The dynamic properties of single olivocochlear efferent neurones in the guinea pig cochlea were examined using sinusoidally amplitude modulated (AM) pure tones. The neural discharge, when displayed as a cyclic histogram, clearly followed the rapid fluctuations in the continuous input sound. Modulation transfer functio...

journal_title：Hearing research

authors： Gummer M,Yates GK,Johnstone BM

更新日期：1988-10-01 00:00:00

abstract：:Delayed acoustic waves have been measured in the sealed ear canal in response to click and tone-burst stimuli. The response shows compressive nonlinearity, evidence for 'active' processing, and frequency tuning. At low sound levels group and phase delays correspond, and represent about 15 waves delay for the mid-frequ...

journal_title：Hearing research

authors： Wilson JP

更新日期：1980-06-01 00:00:00

abstract：:Electrically evoked auditory brainstem response (EABR) recordings were made from 38 humans implanted with one of three cochlear prostheses, and from 25 cats. Recognizable auditory potentials were identified in 27 of the profoundly deaf implanted subjects. In both cats and humans EABR waveform morphology and magnitude ...

journal_title：Hearing research

authors： van den Honert C,Stypulkowski PH

更新日期：1986-01-01 00:00:00

abstract：:Measurements were made of inner hair cell receptor potentials and basilar membrane motion in the 17-21 kHz region of the guinea pig cochlea. The latter were made using the Mossbauer technique. Isoamplitude curves at 0.9 mV d.c. receptor potential were compared with isovelocity curves at 0.04 mm/s and the corresponding...

journal_title：Hearing research

authors： Sellick PM,Patuzzi R,Johnstone BM

更新日期：1983-04-01 00:00:00

abstract：:In the cochlea, outer hair cells (OHCs) and Deiters' cells most likely contribute to the generation of active cochlear mechanics. The presence of ATP receptors on these cells indicates that endogenous ATP may have a role in cochlear mechanics. To explore this possibility, the effects of ATP antagonists were studied bo...

journal_title：Hearing research

authors： Skellett RA,Chen C,Fallon M,Nenov AP,Bobbin RP

更新日期：1997-09-01 00:00:00

abstract：:The auditory "octave illusion" arises when dichotic tones, presented one octave apart, alternate rapidly between the ears. This study aimed to explore the link between the perception of illusory pitches and brain activity during presentation of dichotic tones. We conducted a behavioral study of how participants percei...

journal_title：Hearing research

authors： Tanaka K,Kurasaki H,Kuriki S

更新日期：2018-03-01 00:00:00

abstract：:Cochlear implant recipients show improved speech perception and music appreciation when residual acoustic hearing is combined with the cochlear implant. However, up to one third of patients lose their pre-operative residual hearing weeks to months after implantation, for reasons that are not well understood. This stud...

journal_title：Hearing research

authors： Rowe D,Chambers S,Hampson A,Eastwood H,Campbell L,O'Leary S

更新日期：2016-03-01 00:00:00

abstract：:Songbirds spend much of their time learning, producing, and listening to complex vocal sequences we call songs. Songs are learned via cultural transmission, and singing, usually by males, has a strong impact on the behavioral state of the listeners, often promoting affiliation, pair bonding, or aggression. What is it ...

journal_title：Hearing research

authors： Rothenberg D,Roeske TC,Voss HU,Naguib M,Tchernichovski O

更新日期：2014-02-01 00:00:00

abstract：:The superior colliculus (SC) is critical for directing accurate head and eye movements to visual and acoustic targets. In visual cortex, areas involved in orienting of the head and eyes to a visual stimulus have direct projections to the SC. In auditory cortex of the cat, four areas have been identified to be critical...

journal_title：Hearing research

authors： Chabot N,Mellott JG,Hall AJ,Tichenoff EL,Lomber SG

更新日期：2013-06-01 00:00:00

abstract：:The uptake of two tritiated carbohydrates, D-[3H]-glucosamine and L-[3H]-fucose, to the developing rat cochlea was examined using light and electron microscopic radioautography. Both carbohydrates, administered to in vitro developing rat cochleas, shared a similar ultrastructural labeling pattern on the microvilli and...

journal_title：Hearing research

authors： Gil-Loyzaga P,Gabrion J,Remezal M,Nguyen-Than-Dao B,Uziel A

更新日期：1991-12-01 00:00:00

abstract：:Although the neural mechanisms underlying pitch perception are not yet fully understood, there is general agreement that place and temporal representations of pitch are both used by the auditory system. This paper describes a neural network model of pitch perception that integrates both codes of pitch and explores the...

journal_title：Hearing research

authors： Erfanian Saeedi N,Blamey PJ,Burkitt AN,Grayden DB

更新日期：2017-02-01 00:00:00

abstract：:Prior research [Caine et al., 1981] suggested that scopolamine, a central cholinergic antagonist, may increase gap thresholds in young human listeners. If confirmed, an effect of scopolamine on gap detection might help to explain why both aged humans and aged laboratory animals have less sensitive temporal acuity on g...

journal_title：Hearing research

authors： Ison JR,Bowen GP

更新日期：2000-07-01 00:00:00

abstract：:Noise trauma, aging, and ototoxicity preferentially damage the outer hair cells of the inner ear, leading to increased hearing thresholds and poorer frequency resolution. Whereas outer hair cells make synaptic connections with less than 10% of afferent auditory nerve fibers (type-II), inner hair cells make connections...

journal_title：Hearing research

authors： Lobarinas E,Salvi R,Ding D

更新日期：2013-08-01 00:00:00