Involvement of calcium in the stimulation of phosphatidylcholine secretion in primary cultures of rat type II pneumocytes by Escherichia coli lipopolysaccharide.

abstract：:The endocannabinoids (eCBs) are endogenous arachidonoyl-containing lipid mediators with important roles in host defense. Macrophages are first-line defenders of the innate immune system and biosynthesize large amounts of eCBs when activated. The cellular levels of eCBs are controlled by the activities of their biosynt...

journal_title：Molecular and cellular biochemistry

authors： Lee JH,Hou X,Kummari E,Borazjani A,Edelmann MJ,Ross MK

更新日期：2018-07-01 00:00:00

abstract：:Silkworm (Bombyx mori) is not only a model organism for scientific studies, but also a commercial insect for agricultural production. BmAtg8 (a B. mori homolog of yeast Atg8) plays crucial roles in macroautophagy (hereafter referred to autophagy), which is helpful for silkworm metamorphosis. Relevant mechanism about B...

journal_title：Molecular and cellular biochemistry

authors： Xue S,Mao F,Hu D,Yan H,Lei J,Obeng E,Zhou Y,Quan Y,Yu W

更新日期：2019-07-01 00:00:00

abstract：:To define metabolic influences on cardiac myosin expression and sarcoplasmic reticulum (SR) Ca(2+)-stimulated ATPase streptozotocin-diabetic rats were treated for 9-10 wk with etomoxir, an inhibitor of carnitine palmitoyl transferase I (CPT-1) and fatty acid synthesis, or an antilipolytic drug, acipimox. Etomoxir redu...

journal_title：Molecular and cellular biochemistry

authors： Rupp H,Elimban V,Dhalla NS

更新日期：1994-03-16 00:00:00

abstract：:Long-chain fatty acids (e.g. arachidonic acid) have been implicated in physiological control of insulin secretion. We previously reported histidine phosphorylation of at least two islet proteins (e.g., NDP kinase and the beta subunit of trimeric G-proteins), and suggested that such a signalling step may have regulator...

journal_title：Molecular and cellular biochemistry

authors： Kowluru A

更新日期：2004-11-01 00:00:00

abstract：:Cardiac muscle development is characterised by the activation of contractile protein genes and subsequent modulation of expression resulting, ultimately, in the formation of a mature four-chambered organ. Myocardial gene expression is also altered in the adult in response to pathological stimuli and this is thought to...

journal_title：Molecular and cellular biochemistry

authors： Barton PJ,Felkin LE,Koban MU,Cullen ME,Brand NJ,Dhoot GK

更新日期：2004-08-01 00:00:00

abstract：:Evidence suggests that functional atrial natriuretic peptide (ANP) receptors occur in surface gastric mucosal epithelial cells. To evaluate functional aspects of ANP in a model of these cells we examined the expression of natriuretic peptide receptors (NPR) subtypes A and C in the non-transformed rat gastric mucosal e...

journal_title：Molecular and cellular biochemistry

authors： Gower WR Jr,Carter GM,McAfee Q,Solivan SM

更新日期：2006-12-01 00:00:00

abstract：:Inactivation of the Staphylococcus aureus tricarboxylic acid (TCA) cycle delays the resolution of cutaneous ulcers in a mouse soft tissue infection model. In this study, it was observed that cutaneous lesions in mice infected with wild-type or isogenic aconitase mutant S. aureus strains contained comparable inflammato...

journal_title：Molecular and cellular biochemistry

authors： Massilamany C,Gangaplara A,Gardner DJ,Musser JM,Steffen D,Somerville GA,Reddy J

更新日期：2011-09-01 00:00:00

abstract：:The evolution of pyruvate carboxylase has been studied in rat liver and kidney during perinatal development. The pyruvate carboxylase activity, amount of enzyme and mRNA levels have been assayed from 2 days before delivery to weaning. In liver, there is a peak of activity and amount of enzyme 24 h before delivery and ...

journal_title：Molecular and cellular biochemistry

authors： Salto R,Girón MD,del Mar Sola M,Vargas AM

更新日期：1999-10-01 00:00:00

abstract：:Inhalation of silica in a number of occupational settings can result in debilitating and costly lung disease. It is thought that the pathological replacement of functional lung tissue with fibrotic lesions in silica-induced lung disease is the result of chronic inflammation mediated by products of the silica-exposed a...

journal_title：Molecular and cellular biochemistry

authors： Chen F,Shi X

更新日期：2002-05-01 00:00:00

abstract：:We have observed that phospholipids and protein of the catecholamine (CA) storage granules, i.e. the chromaffin granules, interact in an in vitro system to form liposomal particles, which in many respects resemble the intact matrix of the bovine chromaffin granule. A model has been suggested which consists of an aqueo...

journal_title：Molecular and cellular biochemistry

authors： Helle KB,Serck-Hanssen G

更新日期：1975-02-28 00:00:00

abstract：:Hypermethylation of promoter CpG islands represents an alternative mechanism to inactivate tumor suppressor genes. This study was to detect promoter methylation status and mRNA expression levels of ARRDC3, ELP3, GATA5, and PAX6, and to explore the association between methylation and expression in invasive ductal carci...

journal_title：Molecular and cellular biochemistry

authors： Wang D,Yang PN,Chen J,Zhou XY,Liu QJ,Li HJ,Li CL

更新日期：2014-11-01 00:00:00

abstract：:Endochondral ossification, an important stage of fracture healing, is regulated by a variety of signaling pathways. Transforming growth factor β (TGFβ) superfamily plays important roles and comprises TGFβs, bone morphogenetic proteins (BMPs), and growth differentiation factors. TGFβs primarily regulate cartilage forma...

journal_title：Molecular and cellular biochemistry

authors： Sheu TJ,Zhou W,Fan J,Zhou H,Zuscik MJ,Xie C,Yin G,Berk BC

更新日期：2014-12-01 00:00:00

abstract：:Proton pump inhibitors (PPIs) are widely used to treat hyperacid secretion and stomach ulcers. The study investigated the anti-secretory and anti-ulcer effects of esomeprazole, the S-isomer of omeprazole on dimaprit, histamine and dibutyryl adenosine 3, 5 cyclic monophosphate (dbcAMP)-evoked gastric acid secretion, ac...

journal_title：Molecular and cellular biochemistry

authors： Bastaki SM,Chandranath IS,Singh J

更新日期：2008-02-01 00:00:00

abstract：:The influence of hypotonic solution on cell volume and electrophysiology properties of the failing heart of cardiomyopathic hamsters (TO-2) was investigated. The results showed an increase in cell volume of quiescent isolated ventricular myocytes by 66% within 30 min. Angiotensin (1-7) [Ang (1-7)] (10(-8) M) administe...

journal_title：Molecular and cellular biochemistry

authors： De Mello WC

更新日期：2009-10-01 00:00:00

abstract：:Recent studies have shown that adult osteoporosis could be induced by ageing and estrogen deficiency and homocysteine (Hcy) is an independent risk factor of fracture in osteoporosis patients. In this study, we found hypermethylation of the promoter A region in the estrogen receptor alpha (ERα) gene, and methylation in...

journal_title：Molecular and cellular biochemistry

authors： Lv H,Ma X,Che T,Chen Y

更新日期：2011-09-01 00:00:00

abstract：:Recently it has been demonstrated that hydroxylamine is an activator of triglyceride catabolism. We have studied the effect of hydroxylamine on isocitrate lyase activity and lipid catabolism and have noted a stimulation of isocitrate lyase biosynthesis by 5 mM hydroxylamine. The specificity of this effect was tested w...

journal_title：Molecular and cellular biochemistry

authors： Vanni P,Vincenzini MT,Vincieri F,Baccari V

更新日期：1977-04-12 00:00:00

abstract：:The possibility of amino acids biosynthesis from sucrose, metabolites of Krebs cycle or glyoxylate and ammonium by intact bacteroids has been studied. The suspension of intact Rhizobium lupini bacteroids in phosphate buffer solution pH 7.8 was shown to catalyse the biosynthesis from sucrose and ammonium of some amino ...

journal_title：Molecular and cellular biochemistry

authors： Kretovich WL,Kariakina TI,Kazakova OV,Sidelnikova LI,Kaloshina GS,Shaposhnikov GL

更新日期：1983-01-01 00:00:00

abstract：:Though, it is quite well-known how retinoic acid (RA) is able to induce neuritogenesis in different in vitro models, the putative role exerted by reactive oxygen species (ROS) during this process still need to be further studied. For such purpose, we used a neuronal-like cell line (SH-SY5Y cells) in order to investiga...

journal_title：Molecular and cellular biochemistry

authors： da Frota Junior ML,Pires AS,Zeidán-Chuliá F,Bristot IJ,Lopes FM,de Bittencourt Pasquali MA,Zanotto-Filho A,Behr GA,Klamt F,Gelain DP,Moreira JC

更新日期：2011-12-01 00:00:00

abstract：:Twenty-six days of fat deficiency brought about a decrease of linoleic and an increase of oleic acid in rough endoplasmic reticulum (RER) of guinea pig liver. Arachidonic acid was only slightly decreased in some phospholipids whereas eicose-5,8,11-trienoic acid was not enhanced except in phosphatidyl-inositol. All the...

journal_title：Molecular and cellular biochemistry

authors： Soulages JL,Brenner RR

更新日期：1987-12-01 00:00:00

abstract：:Xanthine oxidase was purified from bovine milk-fat globule membrane by extraction with butan-1-ol, precipitation with ammonium sulphate, separation by preparative electrofocusing and chromatography on Concanavalin-A/Agarose. The enzyme had an A280/A450 ratio of 4.8 and a specific activity of 3.09. At least five to sev...

journal_title：Molecular and cellular biochemistry

authors： Sullivan CH,Mather IH,Greenwalt DE,Madara PJ

更新日期：1982-04-16 00:00:00

abstract：:Accumulating data have shown that microRNAs are involved in the pathogenesis of cancer. miR-202 has been confirmed to be downregulated in several types of human cancer. However, the expression and biological role of miR-202 in osteosarcoma (OS) carcinogenesis and progression remain unclear. In this study, we demonstra...

journal_title：Molecular and cellular biochemistry

authors： Sun Z,Zhang T,Hong H,Liu Q,Zhang H

更新日期：2014-12-01 00:00:00

abstract：:We investigated retinol effects in ornithine decarboxylase activity in Sertoli cells. We also tested the hypothesis that free radical scavengers and iron chelators may attenuate the effect of retinol. Sertoli cells isolated from 15-day-old Wistar rats were previously cultured for 48 h and then treated with retinol by ...

journal_title：Molecular and cellular biochemistry

authors： Klamt F,Dal-Pizzol F,Ribeiro NC,Bernard EA,Benfato MS,Moreira JC

更新日期：2000-05-01 00:00:00

abstract：:The present study is designed to investigate the effect of myocardial preconditioning with oxidative stress induced by pyrogallol or H2O2, on ischaemia-reperfusion induced myocardial injury. Isolated perfused rat heart was subjected to global ischaemia for 30 min followed by reperfusion for 120 min. Coronary effluent ...

journal_title：Molecular and cellular biochemistry

authors： Sharma A,Singh M

更新日期：2001-03-01 00:00:00

abstract：:Chromium (VI) compounds are widely recognized as human carcinogens. Extensive studies in vitro and in model systems indicate that the reactive intermediate, Cr (V), generated by cellular reduction of Cr (VI), is likely the candidate for the ultimate carcinogenic form of chromium compounds. Here we review our current u...

journal_title：Molecular and cellular biochemistry

authors： Liu KJ,Shi X

更新日期：2001-06-01 00:00:00

abstract：:The continuous advancements in cancer research have contributed to the overwhelming evidence of the presence of telomerase in primary and secondary tumours together with hsp90 and c-Myc. This review will discuss the important role of telomerase together with hsp90 and c-Myc within the initiation and progression of gli...

journal_title：Molecular and cellular biochemistry

authors： Shervington A,Cruickshanks N,Wright H,Atkinson-Dell R,Lea R,Roberts G,Shervington L

更新日期：2006-02-01 00:00:00

abstract：:Recent evidence indicated that endocan may be a potential cell marker and a new target for cancers including acute leukemia since the serum endocan level in patients with acute leukemia was associated with the status of the disease, i.e., endocan was higly expressed in untreated acute leukemia, but decreased after che...

journal_title：Molecular and cellular biochemistry

authors： Xu Z,Zhang S,Zhou Q,Wang Y,Xia R

更新日期：2014-10-01 00:00:00

abstract：:In myocardial cells (MCs), endothelin-1 (ET-1) exerts various effects such as hypertrophy, and causes cellular injury. Long-term treatment with an endothelin-A (ET(A)) receptor antagonist improves the survival of rats with heart failure, suggesting that myocardial endothelin system contributes to the progression of he...

journal_title：Molecular and cellular biochemistry

authors： Ueyama T,Kawashima S,Sakoda T,Rikitake Y,Ishida T,Kawai M,Namiki M,Yokoyama M

更新日期：1999-09-01 00:00:00

abstract：:Atherosclerotic lesions occur as a result of excess lipid deposition within the vascular tissues. The peroxisome proliferator-activated receptors (PPARs) present in adipose and hepatic tissues have been shown to promote fatty acid oxidation and lipid storage. An immunohistochemical assessment of PPARalpha and PPARgamm...

journal_title：Molecular and cellular biochemistry

authors： Zahradka P,Yurkova N,Litchie B,Moon MC,Del Rizzo DF,Taylor CG

更新日期：2003-04-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are two hormones produced and secreted by the heart to control blood pressure, body fluid homeostasis and electrolyte balance. Each peptide binds to a common family of 3 receptors (GC-A, GC-B and C-receptor) with varying degrees of affinity. The pro...

journal_title：Molecular and cellular biochemistry

authors： Tse MY,Watson JD,Sarda IR,Flynn TG,Pang SC

更新日期：2001-03-01 00:00:00

abstract：:Nucleocytoplasmic transport of transcription factors is essential in eukaryotes. We previously reported the presence of two functional NLSs in the homeodomain protein, aristaless-related homeobox (Arx) protein, which is a key transcriptional repressor of LMO1, SHOX2, and PAX4 during development. NLS2, that overlaps th...

journal_title：Molecular and cellular biochemistry

authors： Ye W,Lin W,Tartakoff AM,Ma Q,Tao T

更新日期：2013-09-01 00:00:00