Cell swelling, impulse conduction, and cardiac arrhythmias in the failing heart. Opposite effects of angiotensin II and angiotensin (1-7) on cell volume regulation.

abstract：:In this study we assessed activities of antioxidant enzymes, lipid peroxidation end-products, and nitric oxide (NO) levels in women with postmenopausal osteoporosis (PMO). Relationship between oxidative stress parameters and NO levels with bone mineral density (BMD) and clinical variables influencing bone mass and hea...

journal_title：Molecular and cellular biochemistry

authors： Ozgocmen S,Kaya H,Fadillioglu E,Aydogan R,Yilmaz Z

更新日期：2007-01-01 00:00:00

abstract：:Lysosomes are defined traditionally with the marker enzyme acid phosphatase. We showed recently that lysosomes from human fibroblasts can be separated into a light and dense fraction as well as prelysosomal population. We now provide evidence that although acid phosphatase is enriched in all three fractions, the marke...

journal_title：Molecular and cellular biochemistry

authors： Kelly BM,Waheed A,Van Etten R,Chang PL

更新日期：1989-06-01 00:00:00

abstract：:Resveratrol (trans-3,5,4'-trihydroxystilbene), a compound found largely in the skins of red grapes and wines, possesses anti-cancer and anti-angiogenic properties and protects the cardiovascular system. However, the molecular mechanisms by which resveratrol inhibits angiogenesis are currently subjects of intense inves...

journal_title：Molecular and cellular biochemistry

authors： Srivastava RK,Unterman TG,Shankar S

更新日期：2010-04-01 00:00:00

abstract：:Henna leaf (Lawsonia inermis), commonly known as Mehndi is cultivated throughout India and is a very popular natural dye to color hand and hair. It is an integral part of indigenous culture, and is also known for its medicinal value. The effect of 200 and 400 mg/kg body weight of 80% ethanolic extract of the fresh lea...

journal_title：Molecular and cellular biochemistry

authors： Dasgupta T,Rao AR,Yadava PK

更新日期：2003-03-01 00:00:00

abstract：:Recent studies indicate that the mucosa of the urinary bladder may play a major role in the maintenance of normal bladder function. The mucosal surface of the urinary bladder serves as a protective layer against the irritative solutes found in the urine. The integrity of this barrier can be broken by overdistension, a...

journal_title：Molecular and cellular biochemistry

authors： Hypolite JA,Longhurst PA,Gong C,Briscoe J,Wein AJ,Levin RM

更新日期：1993-08-11 00:00:00

abstract：:The constitutive androstane receptor (CAR) has been reported to decrease insulin resistance along with obesity. 6,7-dimethylesculetin (DE) is an active component of Yin Zhi Huang which is a traditional Asian medicine used to treat neonatal jaundice via CAR. In this study, we examined whether DE could affect the expres...

journal_title：Molecular and cellular biochemistry

authors： Masuyama H,Mitsui T,Maki J,Tani K,Nakamura K,Hiramatsu Y

更新日期：2016-08-01 00:00:00

abstract：:This work investigates the effect of alloxan-induced short-term diabetes (24 h) on D-3-hydroxybutyrate metabolism at physiological and non-physiological concentrations of the ketone body in the isolated non-working perfused rat heart. Also the effect of insulin (2 mU.ml-1) on D-3-hydroxybutyrate metabolism was investi...

journal_title：Molecular and cellular biochemistry

authors： Sultan AM

更新日期：1992-03-04 00:00:00

abstract：:The effects of chloroperoxidase [EC 1.1.1.10] and hydrogen peroxide on the viabilities of quiescent and germinating conidiospores of an aflatoxigenic fungus, Aspergillus flavus, were determined. Hydrogen peroxide was found moderately lethal and chloroperoxidase produced a 30-fold increase in the lethality of hydrogen ...

journal_title：Molecular and cellular biochemistry

authors： Jacks TJ,De Lucca AJ,Morris NM

更新日期：1999-05-01 00:00:00

abstract：:Bipolar disorder (BD) is a psychiatric disorder characterized by alternating episodes of mania and depression. The intracerebroventricular (i.c.v) administration of ouabain (a Na(+)/K(+)-ATPase inhibitor) in rats has been used as an animal model of mania, because present face, construct and predictive validities. Seve...

journal_title：Molecular and cellular biochemistry

authors： Freitas TP,Rezin GT,Gonçalves CL,Jeremias GC,Gomes LM,Scaini G,Teodorak BP,Valvassori SS,Quevedo J,Streck EL

更新日期：2010-08-01 00:00:00

abstract：:MicroRNAs play critical roles in the development and progression of non-small cell lung cancer (NSCLC). miR-96 acts as an oncogene in some malignancies, while its role in NSCLC is unclear. Here, we validated that miR-96 was significantly increased in both human NSCLC tissues and cell lines. Inhibition of miR-96 expres...

journal_title：Molecular and cellular biochemistry

authors： Guo H,Li Q,Li W,Zheng T,Zhao S,Liu Z

更新日期：2014-05-01 00:00:00

abstract：:The adipose tissue is an important endocrine organ secreting numerous peptide hormones, including leptin. Increased circulating levels of leptin, as a result of hormonal resistance in obese individuals, may contribute to lower androgen production in obese males. However, the molecular mechanisms involved need to be be...

journal_title：Molecular and cellular biochemistry

authors： Landry DA,Sormany F,Haché J,Roumaud P,Martin LJ

更新日期：2017-09-01 00:00:00

abstract：:MicroRNA-125b (miR-125b) reduces myocardial infarct area and restrains myocardial ischemia reperfusion injury (I/R). In this study, we aimed to investigate the effect of bone marrow mesenchymal stem cell (BMSC)-derived exosomes carrying miR-125b on I/R rats. The myocardial I/R model in rats was constructed by ligation...

journal_title：Molecular and cellular biochemistry

authors： Chen Q,Liu Y,Ding X,Li Q,Qiu F,Wang M,Shen Z,Zheng H,Fu G

更新日期：2020-02-01 00:00:00

abstract：:Molecular hydrogen (H2) is an agent with potential applications in oxidative stress-related and/or inflammatory disorders. H2 is usually administered by inhaling H2-containing air (HCA) or by oral intake of H2-rich water (HRW). Despite mounting evidence, the molecular mechanism underlying the therapeutic effects and t...

journal_title：Molecular and cellular biochemistry

authors： Sobue S,Yamai K,Ito M,Ohno K,Ito M,Iwamoto T,Qiao S,Ohkuwa T,Ichihara M

更新日期：2015-05-01 00:00:00

abstract：:Fatty acid uptake and metabolism are often dysregulated in cancer cells. Fatty acid activation is a critical step that allows these biomolecules to enter cellular metabolic pathways such as mitochondrial β-oxidation for ATP generation or the lipogenic routes that generate bioactive lipids such as the inositol phosphol...

journal_title：Molecular and cellular biochemistry

authors： Radif Y,Ndiaye H,Kalantzi V,Jacobs R,Hall A,Minogue S,Waugh MG

更新日期：2018-11-01 00:00:00

abstract：:Insulin alone at concentrations of less than 1 to 5 uU/ml increased the enzyme activities of glycogen synthase, synthase phosphatase, phosphorylase, and phosphorylase phosphatase in hepatoma H4 cells in culture in the presence and absence of serum. Increase in total and active forms of glycogen synthase and phosphoryl...

journal_title：Molecular and cellular biochemistry

authors： Goheer MA,Larner J,Curnow RT

更新日期：1987-06-01 00:00:00

abstract：:We have observed that phospholipids and protein of the catecholamine (CA) storage granules, i.e. the chromaffin granules, interact in an in vitro system to form liposomal particles, which in many respects resemble the intact matrix of the bovine chromaffin granule. A model has been suggested which consists of an aqueo...

journal_title：Molecular and cellular biochemistry

authors： Helle KB,Serck-Hanssen G

更新日期：1975-02-28 00:00:00

abstract：:Cultured endothelial cells have been used in the past as a source of endothelium-derived relaxing factor (EDRF) and of prostacyclin (PGI2). Although cell cultures are essential for observation of prolonged exposure to media or when there is delayed response, they are time consuming and sterile conditions are essential...

journal_title：Molecular and cellular biochemistry

authors： Kibira S,Dudek R,Narayan KS,Bing RJ

更新日期：1991-11-13 00:00:00

abstract：:The aim of the study was to find out whether administration of selenium (Se) will protect the immature heart against ischemia/reperfusion.The control pregnant rats were fed laboratory diet (0.237 mg Se/kg diet); experimental rats received 2 ppm Na(2)SeO(3) in the drinking water from the first day of pregnancy until da...

journal_title：Molecular and cellular biochemistry

authors： Ostadalova I,Vobecky M,Chvojkova Z,Mikova D,Hampl V,Wilhelm J,Ostadal B

更新日期：2007-06-01 00:00:00

abstract：:The AP-1 consensus sequences (TGAGTCA) are the major 12-O-tetradecanoylphorbol113-acetate (TPA) responsive elements shared by several TPA inducible genes, such as c-sis, c-fos, c-myc, collagenase, stromelysin, hMTIIA and SV40. However, the role of AP-1 binding sites, which are present in the introns 3, 5, and 11 of OD...

journal_title：Molecular and cellular biochemistry

authors： Tseng CP,Verma AK

更新日期：1995-05-10 00:00:00

abstract：:The continuous advancements in cancer research have contributed to the overwhelming evidence of the presence of telomerase in primary and secondary tumours together with hsp90 and c-Myc. This review will discuss the important role of telomerase together with hsp90 and c-Myc within the initiation and progression of gli...

journal_title：Molecular and cellular biochemistry

authors： Shervington A,Cruickshanks N,Wright H,Atkinson-Dell R,Lea R,Roberts G,Shervington L

更新日期：2006-02-01 00:00:00

abstract：:Recent reports considered that it was the disturbance of calcium homeostasis and the accumulation of misfolded proteins in the endoplasmic reticulum (ER) that activated hepatic stellate cells (HSCs) apoptosis and promoted fibrosis resolution. However, the signal-transducing events that are activated by ER stress after...

journal_title：Molecular and cellular biochemistry

authors： Huang Y,Li X,Wang Y,Wang H,Huang C,Li J

更新日期：2014-09-01 00:00:00

abstract：:In an isolated, normothermic rat heart model (Langendorff, 37 degrees C), dimethylthiourea (DMTU) infusion only during reperfusion reduced both injury and measurable hydrogen peroxide (H2O2) concentrations after global ischemia. Cardiac function was assessed by measurement of ventricular developed pressure (DP). H2O2 ...

journal_title：Molecular and cellular biochemistry

authors： Brown JM,Terada LS,Grosso MA,Whitman GJ,Velasco SE,Patt A,Harken AH,Repine JE

更新日期：1988-12-01 00:00:00

abstract：:MAP/Microtubule affinity-regulating kinase 4 (MARK4), a Ser/Thr protein kinases, is related to the Par-1 (partitioning-defective) gene products, and is the human ortholog of Par-1. MARK4 shows its role in the cell polarity at the time of embryonic development. It is mostly located at the basal region of cells, providi...

journal_title：Molecular and cellular biochemistry

authors： Naz F,Islam A,Ahmad F,Hassan MI

更新日期：2015-12-01 00:00:00

abstract：:Tumor suppressor p53 plays important roles in cell cycle regulation, apoptosis and DNA repair in different cell types including lung cancer. There are different p53 apoptotic pathways in high and low metastatic ability lung cancer cells. However, the exactly mechanism in the pathway is still unclear. Here we found tha...

journal_title：Molecular and cellular biochemistry

authors： Huang Y,Jin Y,Yan CH,Yu Y,Bai J,Chen F,Zhao YZ,Fu SB

更新日期：2008-02-01 00:00:00

abstract：:N-cadherin is a transmembrane glycoprotein expressed by mesenchymal origin cells and is located at the adherens junctions. It regulates also cell motility and contributes to cell signaling. In previous studies, we identified that its anomalous expression in bladder carcinoma was a tumor progression marker. A pharmacol...

journal_title：Molecular and cellular biochemistry

authors： Elie-Caille C,Lascombe I,Péchery A,Bittard H,Fauconnet S

更新日期：2020-08-01 00:00:00

abstract：:The acute, as well as late, phase of cardioprotection induced by ischemic preconditioning is abolished in hyperlipidemic (HL) rat heart. The pharmacological inhibition of glycogen synthase kinase-3β (GSK-3β), has earlier been reported to restore this attenuated acute cardioprotective effect. However, it not known whet...

journal_title：Molecular and cellular biochemistry

authors： Yadav HN,Singh M,Sharma PL

更新日期：2012-10-01 00:00:00

abstract：:Ionizing radiation (IR) treatment results in activation of several DNA damage response molecules, such as ataxia telangiectasia, mutated (ATM), and DNA-dependent protein kinase (DNAPK) in mammals that are increasingly recognized for their potential roles in the sensing of DNA damage and initiating the subsequent prote...

journal_title：Molecular and cellular biochemistry

authors： Dhariwala FA,Narang H,Krishna M

更新日期：2012-04-01 00:00:00

abstract：:Early responses of lungs to a single radiation dose of 30 Gy were marked by an inflammatory reaction and the onset of pneumonitis within 4 weeks following hemithorax radiation in the rat. Superoxide dismutase reduced the severity of radiation lesions in lungs. ...

journal_title：Molecular and cellular biochemistry

authors： Malaker K,Das RM

更新日期：1988-12-01 00:00:00

abstract：:Hydrogen sulfide (H2S) has been investigated widely in recent years. H2S plays a variety of roles in different biological systems, including cardiovascular system. It is the final product of amino acids metabolism, which contains sulfur-cysteine and homocysteine (Hcy). In human plasma, there are several various forms ...

journal_title：Molecular and cellular biochemistry

authors： Olas B,Kontek B

更新日期：2015-06-01 00:00:00

abstract：:Signal transduction pathways control various biological processes in cells leading to distinct cellular functions. Protein-protein interactions and post-translational modifications are the physiological events that occur in signaling pathway. p38 MAPK are known to be involved in regulating wide range of cellular proce...

journal_title：Molecular and cellular biochemistry

authors： Rini J,Anbalagan M

更新日期：2017-11-01 00:00:00