Abstract：
:MAP kinases are a family of protein kinases that are ubiquitously expressed and play roles in most signal transduction pathways. They are activated within protein kinase cascades consisting of at least three kinases acting in series. In many, if not all cases, the three-kinase cascade, conveniently referred to as a MAP kinase module, is organized on scaffolds with a variety of forms and functions. This review discusses similarities and differences in scaffolding proteins and mechanisms in yeast, flies, worms and mammals.
journal_name
Cell Calciumjournal_title
Cell calciumauthors
Karandikar M,Cobb MHdoi
10.1054/ceca.1999.0074keywords:
subject
Has Abstractpub_date
1999-11-01 00:00:00pages
219-26issue
5eissn
0143-4160issn
1532-1991pii
S0143-4160(99)90074-Xjournal_volume
26pub_type
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