Abstract：
:An automatic power-generating system (AGS) which converts kinetic energy into electric energy for quartz watches was tested as a power source for implantable cardiac pacemakers. An automatic power-generating mechanism and a capacitor (0.33 F) were removed from a quartz watch (SEIKO) and encapsulated in a polyvinyl case. Characteristics of the AGS were investigated by acceleration equipment. The capacitor in the AGS was charged to 2.0 V (0.66 J) by placing it on the equipment for about 30 minutes. The equipment has a 2 Hz cycle and generates +/- 1.7 G at the end of each half cycle. The AGS (fully charged to 2.0 V) was used as the power source for a pulse generator circuit built using commercially available CMOS IC. The circuit generated pulses of 0.5 ms width at 1 Hz (60 pulses min-1). The voltage of the AGS was maintained at 1.6 V while it was being charged by the accelerations. The generator supplied pulses of 0.75 V, 1.47 mA through a 510 omega load. With fully charged AGS, the generator was also used to pace a mongrel dog's heart at 140 beats min-1 for 60 minutes. During pacing, the AGS supplied 420 mJ to the circuit and the cardiac muscle. The AGS was placed on the right ventricular wall of the mongrel dog under anaesthesia. Energy of 80 mJ is stored in a capacitor by the heart beating at about 200 beats/min for 30 minutes. Thus the AGS generated 13 microJ per heart beat. This result suggests that the AGS may supply enough energy for use in a cardiac pacemaker.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Goto H,Sugiura T,Harada Y,Kazui Tdoi
10.1007/BF02513315keywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
377-80issue
3eissn
0140-0118issn
1741-0444journal_volume
37pub_type
杂志文章abstract：:Axial and transverse components of liquid velocity are measured by laser Doppler anemometer in a perspex tube that has been deformed at one point to resemble the shape of the throat of a partially collapsed flexible tube, conveying fluid while being compressed externally. The Reynolds number is 5900. The flow down-str...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345363
更新日期：2001-07-01 00:00:00
abstract：:We estimated the dynamic cell metabolic activity and the distribution of the pH value and oxygen concentration in tissue samples cultured in vitro by using real-time sensor records and a numerical simulation of the underlying reaction-diffusion processes. As an experimental tissue model, we used chicken spleen slices....
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-015-1367-7
更新日期：2016-05-01 00:00:00
abstract：:Preprocessing, binning and dataset subsampling are investigated with regard to simultaneous maximisation of the speed, accuracy and robustness of CT-3D rotational angiography (3DRA) registration. Clinical diagnosis and treatment can both take advantage of this integration, because 3DRA allows the shape of vessel struc...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02351041
更新日期：2005-09-01 00:00:00
abstract：:A method is presented for automatic analysis of the P-wave, based on lead II of a 12-lead standard ECG, in resting conditions during a routine examination for the detection of patients prone to atrial fibrillation (AF), one of the most prevalent arrhythmias. First, the P-wave was delineated, and this was achieved in t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02347697
更新日期：2002-01-01 00:00:00
abstract：:High-intensity noises are a health hazard for industrial workers, and hearing protection is necessary to prevent hearing loss. Passive methods, such as ear muffs, are ineffective against low-frequency noise. Moreover, many hearing-impaired workers must wear hearing aids to enable communication at their workplace, and ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02430951
更新日期：2005-11-01 00:00:00
abstract：:It is proposed that myo-electric signals can be used to augment conventional speech-recognition systems to improve their performance under acoustically noisy conditions (e.g. in an aircraft cockpit). A preliminary study is performed to ascertain the presence of speech information within myo-electric signals from facia...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345373
更新日期：2001-07-01 00:00:00
abstract：:An atlas-based multimodal registration method for 2-dimension images with discrepancy structures was proposed in this paper. Atlas was utilized for complementing the discrepancy structure information in multimodal medical images. The scheme includes three steps: floating image to atlas registration, atlas to reference...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1808-1
更新日期：2018-11-01 00:00:00
abstract：:Neuronal excitability is determined in a complex way by several interacting factors, such as membrane dynamics, fibre geometry, electrode configuration, myelin impedance, neuronal terminations[Formula: see text] This study aims to increase understanding in excitability, by investigating the impact of these factors on ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1799-y
更新日期：2018-09-01 00:00:00
abstract：:In electrocardiographic imaging (ECGI), one solves the inverse problem of electrocardiography (ECG) to reconstruct equivalent cardiac sources based on the body surface potential measurements and a mathematical model of the torso. Due to attenuation and spatial smoothing within the torso, this inverse problem is ill-po...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-02018-6
更新日期：2019-10-01 00:00:00
abstract：:Monitoring upper-limb activity in a free-living environment is important for the evaluation of rehabilitation. This study is a validation of the Strathclyde Upper-Limb Activity Monitor (SULAM) which records the vertical movement and position of each wrist, and assesses bimanual movement. Agreement between the SULAM an...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0233-7
更新日期：2007-10-01 00:00:00
abstract：:Magnetoenterography (MENG) is a new, non-invasive technique that measures gastrointestinal magnetic signals near the body surface. This study was undertaken to evaluate the temporal and spatial characteristics of the magnetic signals generated by gastric and duodenal slow wave activity. The gastrointestinal magnetic f...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513347
更新日期：1999-09-01 00:00:00
abstract：:An original numerical method is developed to compute the 3D electric potential generated by a dot-contact cuff electrode implanted around an axisymmetrical, inhomogeneous, anisotropic nerve. The technique is based on a 2D finite-element approach coupled with a semi-analytical Fourier spectral decomposition to approxim...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513375
更新日期：1999-11-01 00:00:00
abstract：:Implantable cardioverter defibrillators (ICDs) can store intracardiac electrograms (EGMs) in sinus rhythm (SR), at the onset of spontaneous ventricular tachyarrhythmias (VT) or during their course. This allows the investigation of unknown features of the heart electrical activity associated with different cardiac rhyt...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-005-0014-0
更新日期：2006-03-01 00:00:00
abstract：:Tissue hardness is related to tissue composition, and this is often changed by disease. It is therefore of interest to measure the hardness in an objective and non-invasive way. A tactile sensor based on a vibrating piezoelectric ceramic element in a feedback loop is described. When the sensor touches an object it pro...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513357
更新日期：1999-09-01 00:00:00
abstract：:The fraction of repolarization variability independent of RR interval variability is of clinical interest. It has been linked to direct autonomic nervous system (ANS) regulation of the ventricles in healthy subjects and seems to reflect the instability of the ventricular repolarization process in heart disease. In thi...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-01998-9
更新日期：2019-08-01 00:00:00
abstract：:Both invasive left-ventricular pressure measurements and non-invasive colour M-mode echographic measurements have shown the existence of intraventricular pressure gradients (IVPGs) during early filling. The mechanisms responsible for these IVPG cannot be completely explained by the experiments. Therefore a one-dimensi...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513338
更新日期：1999-07-01 00:00:00
abstract：:The objective of this study was to systematically assess the effects of pharyngeal anatomical details on breathing resistance and acoustic characteristics by means of computational modeling. A physiologically realistic nose-throat airway was reconstructed from medical images. Individual airway anatomy such as the uvul...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-014-1160-z
更新日期：2014-07-01 00:00:00
abstract：:A biphasic continuum model for the flow of intraocular fluid, the aqueous humour, in the trabecular meshwork is proposed in the paper. The model considers the meshwork as a circular ring with uniform thickness of homogeneous, isotropic, viscoelastic material swollen with continuously percolating aqueous humour. The mo...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446710
更新日期：1991-05-01 00:00:00
abstract：:Primary stability of refixated fractures in case of shoulder hemiarthroplasty is a prerequisite to restore physiological glenohumeral joint function. Clinical observations often show a secondary dislocation and subsequent resorption of the bony anchor points like the greater and lesser tuberosity at the rotator cuff t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0483-7
更新日期：2009-05-01 00:00:00
abstract：:Stiffness of the arterial wall and atherosclerotic plaque components is a determinant of the stress field within plaques, which has been suggested to be an indicator of plaque vulnerability. The diversity and inhomogeneous structure of atherosclerotic lesions complicate the characterization of plaque components. In th...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1910-4
更新日期：2019-03-01 00:00:00
abstract：:Soleus muscle flap as coverage tissue is a possible surgical solution adopted to cover the wounds due to open fractures. Despite this procedure presents many clinical advantages, relatively poor information is available about the loss of functionality of triceps surae of the treated leg. In this study, a group of pati...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02286-7
更新日期：2021-01-01 00:00:00
abstract：:In this paper, the limitations of the conventional formula for the computation of peripheral blood flow from impedance plethysmograms are highlighted, and a correction to the formula is suggested. A conductivity cell experiment is described to show the dependence of the value of the blood flow index (BFI), obtained fr...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02524237
更新日期：1994-11-01 00:00:00
abstract：:Past decades witnessed the expansion of linear signal processing methods in numerous biomedical applications. However, the nonlinear behavior of biomedical signals revived the interest in nonlinear signal processing methods such as higher-order statistics, in particular higher-order cumulants (HOC). In this paper, HOC...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-015-1394-4
更新日期：2015-11-01 00:00:00
abstract：:The purpose of the study was to explore the application of artificial neural network model in the auxiliary diagnosis of lung cancer and compare the effects of back-propagation (BP) neural network with Fisher discrimination model for lung cancer screening by the combined detections of four biomarkers of p16, RASSF1A a...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1585-7
更新日期：2017-08-01 00:00:00
abstract：:The aim of the study is to determine the effects of wound, patient and treatment attributes on the wound healing rate and to propose a system for wound healing rate prediction. Predicting the wound healing rate from the initial wound, patient and treatment data collected in a database of 300 chronic wounds is not poss...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345144
更新日期：2001-09-01 00:00:00
abstract：:A method for making a current-ratio map to determine the ischaemic area of angina pectoris (AP) patients has been developed. This method uses a current-arrow map calculated using a ORS wave from 64-channel magnetocardiogram (MCG) signals. The current-ratio map can be calculated from the ratio of an exercise-induced cu...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345263
更新日期：2001-01-01 00:00:00
abstract：:During scoliosis instrumentation surgery, it is difficult for surgeons fully to track vertebral motion in 3D, because only the posterior elements of the spine are exposed. Different intra-operative modelling approaches are evaluated using a registration technique that matches intra-operative measurements with a 3D pre...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513328
更新日期：1999-07-01 00:00:00
abstract：:A novel laser Doppler flowmetry scheme is reported that adjusts the processing bandwidth adaptively to optimise the estimation of flow. To obtain an adequate processing bandwidth, the Doppler spectra is first fitted to the Lorentzian function, and the bandwidth at half the maximum of the Lorentzian function is used as...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344700
更新日期：2004-05-01 00:00:00
abstract：:One challenge in the current research of brain-computer interfaces (BCIs) is how to classify time-varying electroencephalographic (EEG) signals as accurately as possible. In this paper, we address this problem from the aspect of updating feature extractors and propose an adaptive feature extractor, namely adaptive com...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0107-4
更新日期：2006-10-01 00:00:00
abstract：:The passive and active properties of the cochlear outer hair cell are studied. The outer hair cell is currently considered the major candidate for the active component of mammalian hearing. Understanding of its properties may explain the amplification and sharp frequency selectivity of the ear. To analyse the cell beh...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513294
更新日期：1999-03-01 00:00:00
