当前位置： SCI文献检索 > MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING期刊下所有文献 > Progressive changes of elastic moduli of arterial wall and atherosclerotic plaque components during plaque development in human coronary arteries.

Progressive changes of elastic moduli of arterial wall and atherosclerotic plaque components during plaque development in human coronary arteries.

Abstract：

:Stiffness of the arterial wall and atherosclerotic plaque components is a determinant of the stress field within plaques, which has been suggested to be an indicator of plaque vulnerability. The diversity and inhomogeneous structure of atherosclerotic lesions complicate the characterization of plaque components. In the present study, stiffness of the arterial wall and atherosclerotic plaque components in human coronary arteries was examined in early and developed atherosclerotic lesions. The force-spectroscopy mode of the atomic force microscope and histological examination were used for determination of elastic moduli at specified locations within samples. Fibrous cap (E = 14.1 ± 3.8 kPa) showed lower stiffness than the fibrous tissue beneath the lipid pool (E = 17.6 ± 3.2 kPa). Calcification zones (E = 96.1 ± 18.8 kPa) and lipid pools (E = 2.7 ± 1.8 kPa) were the stiffest and softest components of atherosclerotic lesions, respectively. The increase of media stiffness (%44.8) and reduction of the elastic modulus of the internal elastic lamina (%28.9) was observed in coronary arteries. Moreover, significant differences were observed between the stiffness of medial layer in diseased parts and free-plaque segments in incomplete plaques of coronary arteries. Our results can be used for better understanding of remodeling mechanisms of the arterial wall with plaque development. Graphical abstract Stiffness alteration of the arterial wall and atherosclerotic plaque components with plaque development in coronary arteries.

journal_name

Med Biol Eng Comput

journal_title

Medical & biological engineering & computing

authors

Rezvani-Sharif A,Tafazzoli-Shadpour M,Avolio A

doi

10.1007/s11517-018-1910-4

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

731-740

issue

3

eissn

0140-0118

issn

1741-0444

pii

10.1007/s11517-018-1910-4

journal_volume

57

pub_type

杂志文章

相关文献

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING文献大全
  • Estimation of respiratory volumes from the photoplethysmographic signal. Part I: Experimental results.

    abstract：:To evaluate the possibility of respiratory-volume measurement using photoplethysmography (PPG), PPG signals from 16 normal volunteers are collected, and the respiratory-induced intensity variations (RIIV) are digitally extracted. The RIIV signals are studied while respiratory volume is varied. Furthermore, respiratory...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02513264

    authors： Johansson A,Oberg PA

    更新日期：1999-01-01 00:00:00

  • Time-varying digital filtering of ECG baseline wander.

    abstract：:Time-varying filtering techniques are applied to the problem of baseline correction by letting the cut-off frequency of a linear filter be controlled by the low-frequency properties of the ECG signal. The time-varying filter is implemented as a bank of linear low-pass filters, in which each filter has a slightly diffe...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02441986

    authors： Sörnmo L

    更新日期：1993-09-01 00:00:00

  • Velocity distribution model for normal blood flow in the human ascending aorta.

    abstract：:During the study of velocities in the human ascending aorta it became necessary to establish a method for two-dimensional velocity profiles from discrete velocity data obtained from different heartbeats and with different techniques. A descriptive geometrical model was therefore developed and expanded to 16 elements e...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02442319

    authors： Segadal L

    更新日期：1991-09-01 00:00:00

  • Dialysate-side urea kinetics. Neural network predicts dialysis dose during dialysis.

    abstract：:Determination of the adequacy of dialysis is a routine but crucial procedure in patient evaluation. The total dialysis dose, expressed as Kt/V, has been widely recognised to be a major determinant of morbidity and mortality in haemodialysed patients. Many different factors influence the correct determination of Kt/V, ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02348080

    authors： Fernández EA,Valtuille R,Willshaw P,Perazzo CA

    更新日期：2003-07-01 00:00:00

  • Fully coupled fluid-structure interaction model of congenital bicuspid aortic valves: effect of asymmetry on hemodynamics.

    abstract：:A bicuspid aortic valve (BAV) is a congenital cardiac disorder where the valve consists of only two cusps instead of three, as in a normal tricuspid valve (TAV). Although 97 % of BAVs include asymmetric cusps, little or no prior studies have investigated the blood flow through a three-dimensional BAV and root. The aim...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-013-1055-4

    authors： Marom G,Kim HS,Rosenfeld M,Raanani E,Haj-Ali R

    更新日期：2013-08-01 00:00:00

  • Angular relational signature-based chest radiograph image view classification.

    abstract：:In a computer-aided diagnosis (CAD) system, especially for chest radiograph or chest X-ray (CXR) screening, CXR image view information is required. Automatically separating CXR image view, frontal and lateral can ease subsequent CXR screening process, since the techniques may not equally work for both views. We presen...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-018-1786-3

    authors： Santosh KC,Wendling L

    更新日期：2018-08-01 00:00:00

  • A new software scheme for scatter correction based on a simple radiographic scattering model.

    abstract：:In common radiography, image contrast is often limited due mainly to scattered x-rays and noise, decreasing the quantitative usefulness of x-ray images. Several scatter reduction methods based on software correction schemes have been extensively investigated in an attempt to overcome these difficulties, most of which ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-018-1893-1

    authors： Kim K,Kang S,Kim W,Park C,Lee D,Cho H,Kang W,Park S,Kim G,Lim H,Lee H,Park J,Jeon D,Lim Y,Woo T,Oh J

    更新日期：2019-02-01 00:00:00

  • Gastric emptying of solids measured by means of magnetised iron oxide powder.

    abstract：:The aim of this study was to develop a radiation-free method to measure gastric emptying. Such a method would be useful e.g. for patients who need repeated measurements and in pregnancy. Ferrimagnetic particles (gamma-Fe2O3), ingested within a solid test meal (pancakes), were magnetised by an applied magnetic field. A...

    journal_title：Medical & biological engineering & computing

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF02522849

    authors： Forsman M

    更新日期：1998-01-01 00:00:00

  • Extraction of Cole parameters from the electrical bioimpedance spectrum using stochastic optimization algorithms.

    abstract：:Fitting the measured bioimpedance spectroscopy (BIS) data to the Cole model and then extracting the Cole parameters is a common practice in BIS applications. The extracted Cole parameters then can be analysed as descriptors of tissue electrical properties. To have a better evaluation of physiological or pathological p...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-015-1355-y

    authors： Gholami-Boroujeny S,Bolic M

    更新日期：2016-04-01 00:00:00

  • A comparison of two Hilbert spectral analyses of heart rate variability.

    abstract：:The present paper compares the performance of two Hilbert spectral analyses when applied to a synthetic RR series from a nonstationary integral pulse frequency modulation model and to real RR series from a dataset of normal sinus arrhythmia. The Hilbert-Huang transformation based on empirical mode decomposition is com...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-009-0500-x

    authors： Ihlen EA

    更新日期：2009-10-01 00:00:00

  • Physiological quality assessment of stored whole blood by means of electrical measurements.

    abstract：:The physiological parameters of blood such as extracellular Na(+), K(+), Cl(-), pH, 2,3-DPG and ATP and the complex electrical impedance were measured using whole blood samples from 31 male donors (21 donors form the training set and ten donors were used for testing), on the 0th, 10th and 21st day of blood bank storag...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-007-0206-x

    authors： Ulgen Y,Sezdi M

    更新日期：2007-07-01 00:00:00

  • Tooth segmentation and gingival tissue deformation framework for 3D orthodontic treatment planning and evaluating.

    abstract：:In this study, we propose an integrated tooth segmentation and gingival tissue deformation simulation framework used to design and evaluate the orthodontic treatment plan especially with invisible aligners. Firstly, the bio-characteristics information of the digital impression is analyzed quantitatively and demonstrat...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-020-02230-9

    authors： Yuan T,Wang Y,Hou Z,Wang J

    更新日期：2020-10-01 00:00:00

  • Experimental and numerical investigation on soft tissue dynamic response due to turbulence-induced arterial vibration.

    abstract：:Peripheral arterial occlusive disease is a serious cardiovascular disorder. The arterial occlusion leads to turbulent flow and arterial sound generation on the inner vessel wall. Stenosis-induced vibro-acoustic waves propagate through the surrounding soft tissues and reach the skin surface. In this study, the feasibil...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-019-01995-y

    authors： Salman HE,Yazicioglu Y

    更新日期：2019-08-01 00:00:00

  • A simulation technique for computation of the dosimetric effects of setup, organ motion and delineation uncertainties in radiotherapy.

    abstract：:In this study, we introduce a novel simulation technique to incorporate delineation errors into radiotherapy treatment margins and combine them with organ motion and set-up errors to investigate the cumulative dosimetric effects in different tumour sites. The effects of applying patient realignment correction protocol...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-010-0616-z

    authors： Mzenda B,Hosseini-Ashrafi M,Palmer A,Liu H,Brown DJ

    更新日期：2010-07-01 00:00:00

  • Biomechanical analysis of the muscular power of martial arts athletes.

    abstract：:This study analyzes the performance of knee extension and flexion of Taekwondo and Kickboxing athletes. The power values were extracted through electromyography obtained by an isokinetic dynamometer at 60 degrees per second. These values are resulted from the square of the electromyography signal. The analysis of kick...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-010-0608-z

    authors： Machado SM,Osório RA,Silva NS,Magini M

    更新日期：2010-06-01 00:00:00

  • Automatic identification of motor unit action potential trains from electromyographic signals using fuzzy techniques.

    abstract：:A technique is proposed that allows automatic decomposition of electromyographic (EMG) signals into their constituent motor unit action potential trains (MUAPTs). A specific iterative algorithm with a classification method using fuzzy-logic techniques was developed. The proposed classification method takes into accoun...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02349972

    authors： Chauvet E,Fokapu O,Hogrel JY,Gamet D,Duchêne J

    更新日期：2003-11-01 00:00:00

  • Application of mechanical mobility of periodontal tissues to tooth mobility examination.

    abstract：:Tooth mobility examination is important in planning dental treatment, as it may give an indication of alveolar bone loss and the condition of the periodontal ligament. In clinical dental diagnosis a manual tooth mobility examination is useful. However, its determination of tooth mobility is subjective and depends on t...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02442173

    authors： Oka H,Yamamoto T,Saratani K,Kawazoe T

    更新日期：1989-01-01 00:00:00

  • Regulation of neurofilament interactions in vitro by natural and synthetic polypeptides sharing Lys-Ser-Pro sequences with the heavy neurofilament subunit NF-H: neurofilament crossbridging by antiparallel sidearm overlapping.

    abstract：:Neurofilaments are organised into parallel bundles in axons through crossbridges formed by lateral projections of neurofilament subunits. Pure neurofilaments form gels in vitro, consisting of interconnected parallel arrays of filaments regulated by the phosphorylation level of neurofilament subunits. Neurofilament-ass...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02522486

    authors： Gou JP,Gotow T,Janmey PA,Leterrier JF

    更新日期：1998-05-01 00:00:00

  • Classification of pure conduct disorder from healthy controls based on indices of brain networks during resting state.

    abstract：:Conduct disorder (CD) is an important mental health problem in childhood and adolescence. There is presently a trend of revealing neural mechanisms using measures of brain networks. This study goes further by presenting a classification scheme to distinguish subjects with CD from typically developing healthy subjects ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-020-02215-8

    authors： Zhang J,Liu Y,Luo R,Du Z,Lu F,Yuan Z,Zhou J,Li S

    更新日期：2020-09-01 00:00:00

  • Noninvasive measurement of blood glucose concentrations by analysing Fourier transform infra-red absorbance spectra through oral mucosa.

    abstract：:Whether Fourier transform infra-red spectroscopy with an attenuated total reflection prism could be applied for noninvasive glucose measurement through oral mucosa was evaluated. As a result, the same absorbance peak at 1033 cm-1 as in glucose aqueous solution was found in the absorbance spectra through mucous membran...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02446645

    authors： Kajiwara K,Uemura T,Kishikawa H,Nishida K,Hashiguchi Y,Uehara M,Sakakida M,Ichinose K,Shichiri M

    更新日期：1993-07-01 00:00:00

  • Automatic lesion segmentation and classification of hepatic echinococcosis using a multiscale-feature convolutional neural network.

    abstract：:Hepatic echinococcosis (HE) is a life-threatening liver disease caused by parasites that requires a precise diagnosis and proper treatments. To assess HE lesions accurately, we propose a novel automatic HE lesion segmentation and classification network that contains lesion region positioning (LRP) and lesion region se...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-020-02126-8

    authors： Xin S,Shi H,Jide A,Zhu M,Ma C,Liao H

    更新日期：2020-03-01 00:00:00

  • Displacement of alveolar macrophages in air space of human lung.

    abstract：:The role of alveolar macrophages in the process of the human lung clearance is summarised. Three patterns of alveolar macrophage (AM) displacement on the surface of alveolus are distinguished depending on the loading of the surface with insoluble deposits, i.e. directional, directional with small stochastic noise and ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02522517

    authors： Gradoń L,Podgórski A

    更新日期：1995-07-01 00:00:00

  • Beat-to-beat estimation of stroke volume using impedance cardiography and artificial neural network.

    abstract：:Impedance cardiography is a low-cost noninvasive technique, based on monitoring of the thoracic impedance, for estimation of stroke volume (SV). Impedance cardiogram (ICG) is the negative of the first derivative of the impedance signal. A technique for beat-to-beat SV estimation using impedance cardiography and artifi...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-017-1752-5

    authors： Naidu SMM,Pandey PC,Bagal UR,Hardas SP

    更新日期：2018-06-01 00:00:00

  • Uncertainty assessment of gamma-aminobutyric acid concentration of different brain regions in individual and group using residual bootstrap analysis.

    abstract：:The aim of this work is to quantify individual and regional differences in the relative concentration of gamma-aminobutyric acid (GABA) in human brain with in vivo magnetic resonance spectroscopy. Spectral editing Mescher-Garwood point resolved spectroscopy (MEGA-PRESS) sequence and GABA analysis toolkit (Gannet) were...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-016-1579-5

    authors： Chen M,Liao C,Chen S,Ding Q,Zhu D,Liu H,Yan X,Zhong J

    更新日期：2017-06-01 00:00:00

  • Enrichment of cardiac pacemaker-like cells: neuregulin-1 and cyclic AMP increase I(f)-current density and connexin 40 mRNA levels in fetal cardiomyocytes.

    abstract：:Generation of a large number of cells belonging to the cardiac pacemaker system would constitute an important step towards their utilization as a biological cardiac pacemaker system. The aim of the present study was to identify factors, which might induce transformation of a heterogenous population of fetal cardiomyoc...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-007-0164-3

    authors： Ruhparwar A,Er F,Martin U,Radke K,Gruh I,Niehaus M,Karck M,Haverich A,Hoppe UC

    更新日期：2007-02-01 00:00:00

  • Estimation of mean arterial pressure from the oscillometric cuff pressure: comparison of different techniques.

    abstract：:Mean arterial pressure (MAP) is determined in most automated oscillometric blood pressure devices, but its derivation has been little studied. In this research, different techniques were studied and compared with the auscultatory technique. Auscultatory systolic and diastolic blood pressure (SBP and DBP) were obtained...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-010-0694-y

    authors： Zheng D,Amoore JN,Mieke S,Murray A

    更新日期：2011-01-01 00:00:00

  • Vascular smooth muscle cells remodel collagen matrices by long-distance action and anisotropic interaction.

    abstract：:While matrix remodeling plays a key role in vascular physiology and pathology, the underlying mechanisms have remained incompletely understood. We studied the remodeling of collagen matrices by individual vascular smooth muscle cells (SMCs), clusters and monolayers. In addition, we focused on the contribution of trans...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-012-0916-6

    authors： van den Akker J,Tuna BG,Pistea A,Sleutel AJ,Bakker EN,van Bavel E

    更新日期：2012-07-01 00:00:00

  • Measurement of retinal vascular tortuosity and its application to retinal pathologies.

    abstract：:The tortuosity of retinal blood vessels is an important diagnostic indicator for a number of retinal pathologies. We applied robust quantitative tortuosity metrics, which are well suited to automated detection and measurement, to retinal fluorescein images of normal and diseased vessels exhibiting background diabetic ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-009-0559-4

    authors： Dougherty G,Johnson MJ,Wiers MD

    更新日期：2010-01-01 00:00:00

  • Influence of synchronous and sequential stimulation on muscle fatigue.

    abstract：:In acute experiments the sciatic nerve of the rat is electrically stimulated to induce fatigue in the medial Gastrocnemius muscle. Fatigue tests are carried out using intermittent stimulation of different compartments (sequential) or a single compartment (synchronous) of the sciatic nerve. The activation of different ...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/BF02530036

    authors： Thomsen M,Veltink PH

    更新日期：1997-05-01 00:00:00

  • ECG signal analysis for the assessment of sleep-disordered breathing and sleep pattern.

    abstract：:The diagnosis of sleep-disordered breathing (SDB) usually relies on the analysis of complex polysomnographic measurements performed in specialized sleep centers. Automatic signal analysis is a promising approach to reduce the diagnostic effort. This paper addresses SDB and sleep assessment solely based on the analysis...

    journal_title：Medical & biological engineering & computing

    pub_type： 杂志文章

    doi：10.1007/s11517-011-0853-9

    authors： Kesper K,Canisius S,Penzel T,Ploch T,Cassel W

    更新日期：2012-02-01 00:00:00