Abstract:
:Dietary supplementation of rats with fish oil for 18 days resulted in signs of lipid peroxidation, with increased malondialdehyde production in plasma and myocardium. This increase in malondialdehyde could be completely prevented by supplementing the fish oil with a new natural antioxidant mixture (Pufanox) which is known to markedly increase the in vitro stability of fish oils. Addition of Pufanox to fish oil also tended to increase the ratio between the vasodilator prostacyclin and the vasoconstrictor thromboxane A2. The concentration of vitamin E decreased, both in plasma and in the heart after the period of fish oil ingestion, indicating that the fish oil used contained too little vitamin E. Plasma cholesterol and triglyceride levels decreased markedly after fish oil supplementation but with no apparent difference between fish oil with or without Pufanox, probably due to the insufficient content of vitamin E. The results obtained emphasize the importance both of the in vitro stability of the fish oil given and of the amount of vitamin E added.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Jokela R,Engström K,Wallin R,Saldeen Tdoi
10.3109/03009739809178950keywords:
subject
Has Abstractpub_date
1998-01-01 00:00:00pages
213-21issue
3eissn
0300-9734issn
2000-1967journal_volume
103pub_type
杂志文章abstract::Allergic alveolitis due to mold dust inhalation in farmers is a severe but rare disease in Scandinavia. In this report 38 cases of the disease are presented. There were 31 men and 7 women, with mean ages of 46 and 38 years respectively. Strict diagnostic criteria were used, resulting in 21 definite, 12 probable and 5 ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738909178568
更新日期:1989-01-01 00:00:00
abstract::A new stimulatory luteinizing hormone-releasing hormone (LRH) analogue D-Ser(TBU)(6)-EA(10)-LRH was administered subcutaneously in a dose of 10 microg into 10 women with amenorrhoea. The injection resulted in a 20-fold increase of the LH level in blood and a 5-fold increase of the FSH level with maxima at 4 and 6 h af...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737709179054
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:Minimally invasive laparoscopic radical prostatectomy (LRP) has proven equally effective as open surgery in terms of cancer control and peroperative complication rate with less bleeding and postoperative pain. However, long-term follow-up data after LRP are scarce, especially as related to quality of life (Q...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.868560
更新日期:2014-03-01 00:00:00
abstract::The bisphosphonates are potent inhibitors of osteoclastic bone resorption that mainly have been used for treatment of hypercalcaemia secondary to malignancy. We have performed a controlled dose-finding study of oral pamidronate that was given to 60 patients with a history of fracture of the distal forearm, an enhanced...
journal_title:Upsala journal of medical sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/03009739109179272
更新日期:1991-01-01 00:00:00
abstract::The lipid metabolism of isolated mouse pancreatic islets, which had been cultured for one week at 3.3 or 16.7 mM glucose, was examined in short-term experiments performed at the end of the culture period. It was found that: a) high-glucose cultured islets oxidized palmitate at a higher rate: and b) both groups of cult...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179210
更新日期:1981-01-01 00:00:00
abstract::Numerous false positive findings are a problem in computed tomography based lung cancer screening trials. The potential patient-related variables that could predict the existence of such lung nodules were studied. 526 construction workers (age 38-81 yrs.) previously screened with spiral computed tomography were evalua...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-242
更新日期:2008-01-01 00:00:00
abstract::Bile salt sulphation in primary biliary cirrhosis was studied by measurements of the liver bile salt sulphotransferase levels in 16 patients. Although the enzyme activity varied among the patients it did not correlate with the severity of cholestasis. Furthermore, the mean bile salt sulphotransferase magnitude in pati...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738309178432
更新日期:1983-01-01 00:00:00
abstract::The present investigation on 20 patients after total hip replacement surgery has confirmed that the posttraumatic increase of the fibrinolysis inhibition activity (FIA) in serum and plasminogen-depleted serum is due to the primary fibrinolysis inhibitor (PFI, alpha 2-antiplasmin). This protein exists in at least two f...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178409
更新日期:1982-01-01 00:00:00
abstract::A thymolipoma in an 8-year-old boy is reported. The tumour had appeared on a routine chest X-ray as a broadened heart shadow and a peculiar right heart contour. Cardiac hypertrophy was suspected primarily. At thoracotomy a thymic tumour was found. ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179036
更新日期:1976-01-01 00:00:00
abstract::Inverse ratio ventilation (IRV) is commonly used in clinical practice. Several studies have used IRV in order to recruit collapsed alveoli. In a randomised trial in twelve surfactant depleted piglets, the lungs were ventilated with sufficient positive end-expiratory pressure (PEEP) to prevent end-expiratory collapse, ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739609178925
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To assess whether the proportion of primary care physicians implementing full body skin examination (FBSE) to screen for melanoma changed over time. METHODS:Meta-regression analyses of available data. DATA SOURCES:MEDLINE, ISI, Cochrane Central Register of Controlled Trials. RESULTS:Fifteen studies surveyi...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,meta分析
doi:10.1080/03009730802579620
更新日期:2009-01-01 00:00:00
abstract::We herein outline the rationale for a Swedish cohort consortium, aiming to facilitate greater use of Swedish cohorts for world-class research. Coordination of all Swedish prospective population-based cohorts in a common infrastructure would enable more precise research findings and facilitate research on rare exposure...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2018.1556754
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:It has recently been reported that patient selection has a strong impact on the agreement between glomerular filtration rate (GFR) estimates from serum cystatin C and creatinine. The aim of our study was to evaluate the effect of creatinine production rate (CPR) on this subject. MATERIAL AND METHODS:GFR was...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.696154
更新日期:2012-11-01 00:00:00
abstract::Familial aggregation of patients with ovarian carcinoma is unusual. A family with four affected members in three consecutive generations is described. The tumors were all of the serous papillary adenocarcinoma type. The pattern of appearance of the malignant disorder in the present family may be explained as the resul...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179047
更新日期:1976-01-01 00:00:00
abstract::Since 1975 Sweden has had a patient insurance system to compensate patients for health-related injuries. The system was initially based on a voluntary patient insurance solution, but in 1997 it was replaced by the Patient Insurance Act. The current Act covers both physical and mental injuries. Although about 9,000-10,...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903350749
更新日期:2010-05-01 00:00:00
abstract::Local heat trauma was induced in rats with alloxan diabetes of 3 days duration. Zinc and copper concentrations in serum, liver, heart and pancreas were estimated. After traumatization there was a decrease of the serum zinc concentration in all animals. The lowest concentration was found in the diabetic animals. Serum ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179172
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:The incidence of fentanyl-induced cough (FIC) during induction of general anesthesia varies around 40% and is undesirable. It increases intracranial, intraocular, and intra-abdominal pressures. This prospective, randomized, double-blind, placebo-controlled study evaluated the effect of dexmedetomidine (DEX) ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,随机对照试验
doi:10.3109/03009734.2011.629749
更新日期:2012-03-01 00:00:00
abstract::Although AL amyloidosis usually is a systemic disease, strictly localized AL deposits are not exceptionally rare. Such case reports form a considerable body of published articles. Although both AL amyloidosis types are formed from an N-terminal segment of a monoclonal immunoglobulin light chain, a typical localized AL...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2012.654861
更新日期:2012-05-01 00:00:00
abstract::The tubuloglomerular feedback mechanism is highly activated in juxtamedullary nephrons and considered to play a major role in intrarenal regulation of glomerular filtration rate. The vasculature of juxtamedullary nephrons is highly vasoreactive with a high ability for vasodilation. This vasoreactivity is a prerequisit...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739209179287
更新日期:1992-01-01 00:00:00
abstract::Factors that may influence the water transport through the skin in infants on their first day of life were studied with a method based on determination of the vapour pressure gradient in the air layer close to the skin surface. The evaporation rate from the skin was found to vary with the site of measurement, ambient ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179207
更新日期:1981-01-01 00:00:00
abstract:AIM:To investigate how individuals fulfilling the Rome II criteria for irritable bowel syndrome (IBS) spontaneously described their symptoms. METHOD:From a general population, 1,244 randomly sampled adults were asked to describe their gastrointestinal symptoms (if any) verbally, in their own words, at a semi-structure...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2015.1040529
更新日期:2015-01-01 00:00:00
abstract::We report a rare case of Langerhans cell histiocytosis involving the sternum. The patient was a 12-year-old girl presenting with anterior chest pain and swelling. Radiographs and computed tomography showed an osteolytic lesion in the sternum. Technetium bone scintigraphy revealed increased uptakes in the sternum, the ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009730802642360
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Diabetic patients exhibit platelet hyperreactivity, which renders them resistant to antithrombotic treatments. We aimed to investigate the prevalence and predictors of aspirin resistance in diabetic patients. MATERIAL AND METHODS:A total of 93 diabetic and 37 non-diabetic participants were included into the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.861549
更新日期:2014-03-01 00:00:00
abstract::Glucagon from the pancreatic α-cells is a major blood glucose-regulating hormone whose most important role is to prevent hypoglycaemia that can be life-threatening due to the brain's strong dependence on glucose as energy source. Lack of blood glucose-lowering insulin after malfunction or autoimmune destruction of the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2016.1154905
更新日期:2016-05-01 00:00:00
abstract::Prototype instruments are developed for determining haemoglobin and glucose content of blood based on optothermal spectroscopy. The optothermal instrument is described. The results of clinical haemoglobin and glucose tests show good agreement with standard methods. For haemoglobin a method reproducibility of better th...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738609178508
更新日期:1986-01-01 00:00:00
abstract::The role of the sympathetic nerve system is still unknown in different types of hypertension. The procedure used in the evaluation of suspect renovascular hypertension has been revised in such a way that renal blood flow, renal arterial blood pressure and plasma renin activity in renal vein could be determined prior t...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179031
更新日期:1976-01-01 00:00:00
abstract::The urine sediment of 12 geriatric patients with indwelling catheters was quantified by the glutaraldehyde-cytocentrifuge method prior to, during and after a clinical trial of methenamine hippurate (MH), 2 g x 3 daily given for 34 days as the sole therapeutic agent for the urinary tract infection. The median leukocyte...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737909179142
更新日期:1979-01-01 00:00:00
abstract::Alkaline phosphatase from calf intestinal mucosa dephosphorylated histone H1 and fibrinogen that had been phosphorylated with protein kinase C. The reaction velocity was dependent on the ionic strength of the buffer; decreasing with increasing concentration. The pH optimum was around 7, which is lower than pH-optima d...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739109179262
更新日期:1991-01-01 00:00:00
abstract::Platelet-derived growth factor B (PDGF-B) is a growth factor promoting and regulating cell migration, proliferation, and differentiation, involved in both developmental processes and in maintaining tissue homeostasis under strict regulation. What are the implications of prolonged or uncontrolled growth factor signalin...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.654860
更新日期:2012-05-01 00:00:00
abstract::In this study we describe an unusual complication in a patient suffering from chronic calcifying pancreatitis. The patient had a fistula between the common bile duct, the pancreatic duct, and the portal vein. He received supportive medical treatment and achieved long-term survival. A review of the literature including...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/2000-1967-059
更新日期:2006-01-01 00:00:00