Abstract:
BACKGROUND:Diabetic patients exhibit platelet hyperreactivity, which renders them resistant to antithrombotic treatments. We aimed to investigate the prevalence and predictors of aspirin resistance in diabetic patients. MATERIAL AND METHODS:A total of 93 diabetic and 37 non-diabetic participants were included into the study. Aspirin resistance was measured with a whole-blood desktop platelet function analyzer (PFA-100) with an epinephrine agonist. RESULTS:Altogether 41.9% patients with DM were aspirin non-responders. Aspirin resistance was observed in 43.2% of non-diabetic patients (p = 0.89). Presence of diabetes mellitus had no effect on aspirin response (RR 0.95 (95% CI 0.44-2.05), p = 0.89) in the whole study population. Hypercholesterolemia was the only predictor of aspirin resistance in multivariate analysis in diabetic patients (RR 3.09 (95% CI 1.17-8.16), p = 0.023). CONCLUSION:The prevalence of aspirin resistance is comparable in diabetic and non-diabetic patients. Hypercholesterolemia is the only independent predictor of aspirin resistance in diabetic patients.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Tasdemir E,Toptas T,Demir C,Esen R,Atmaca Mdoi
10.3109/03009734.2013.861549subject
Has Abstractpub_date
2014-03-01 00:00:00pages
25-31issue
1eissn
0300-9734issn
2000-1967journal_volume
119pub_type
杂志文章abstract::In this study we describe an unusual complication in a patient suffering from chronic calcifying pancreatitis. The patient had a fistula between the common bile duct, the pancreatic duct, and the portal vein. He received supportive medical treatment and achieved long-term survival. A review of the literature including...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/2000-1967-059
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abstract:INTRODUCTION:Research about pregnancy-planning behaviour mostly focuses on women, even though pregnancy planning usually also concerns men. The purpose of this study was to investigate how men plan for family, and to measure their fertility knowledge after having become fathers. MATERIAL AND METHODS:Data were collecte...
journal_title:Upsala journal of medical sciences
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journal_title:Upsala journal of medical sciences
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journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,随机对照试验
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journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,随机对照试验
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更新日期:2007-01-01 00:00:00
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journal_title:Upsala journal of medical sciences
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journal_title:Upsala journal of medical sciences
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