Abstract:
BACKGROUND:Minimally invasive laparoscopic radical prostatectomy (LRP) has proven equally effective as open surgery in terms of cancer control and peroperative complication rate with less bleeding and postoperative pain. However, long-term follow-up data after LRP are scarce, especially as related to quality of life (QoL). AIM:To compare QoL and functional outcomes at least 10 years after LRP with a population-based control group matched for age and region. METHODS:Follow-up data were obtained by mailed questionnaires from patients who responded anonymously to five international questionnaires (EQ-5D, QLQ-C30, QLQ-PR25, IPSS, and IIEF). We collected self-reported outcome data directly from 49 patients who underwent LRP more than 10 years ago in our centre. The results of the patients' overall QoL and urinary continence rates were compared with 918 controls matched for region and age. RESULTS:Forty-two patients (86%) and 808 (88%) controls reported having no urinary leakage. Only 11 patients (24%) still had sexual activities 10 years after LRP, and three were without erectile dysfunction. There was no difference in four of five statements of the self-assessed QoL questionnaires between the LRP and control group. Anxiety level was higher in the LRP group (44%) than in the control group (23%). CONCLUSION:Patients reported high self-assessed QoL, although they also reported low sexual activity 10 years after LRP. Prevalence of urinary leakage was similar in both groups. However, anxiety was more common in LRP patients.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Wang EY,Eriksson HGdoi
10.3109/03009734.2013.868560subject
Has Abstractpub_date
2014-03-01 00:00:00pages
32-7issue
1eissn
0300-9734issn
2000-1967journal_volume
119pub_type
杂志文章abstract::The acute phase reaction is an unspecific response to inflammatory stimuli characterized by alterations in the concentration of several plasma proteins. It is of great clinical value to monitor the inflammatory state in patients with rheumatoid arthritis. The erythrocyte sedimentation rate (ESR) and C-reactive protein...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739809178943
更新日期:1998-01-01 00:00:00
abstract::Isokinetic torque of the knee and elbow during maximal extension and flexion and isometric strength of the handgrip, as well as balance and some circulatory variables, were tested in 37 patients one year after an acute stroke. Correlations with locomotion, household work and other activities of daily living (ADL) were...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178405
更新日期:1982-01-01 00:00:00
abstract::In Uppsala, extensive epidemiological and clinical studies on insulin resistance and diabetes have been ongoing for the past 30 years. A prospective cohort study of men born 1920-24, living in Uppsala County, was initiated during 1969-74 (the Uppsala Longitudinal Study of Adult Men, ULSAM). Risk factors for cardiovasc...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.1517/03009734000000060
更新日期:2000-01-01 00:00:00
abstract::Alkaline phosphatase from calf intestinal mucosa dephosphorylated histone H1 and fibrinogen that had been phosphorylated with protein kinase C. The reaction velocity was dependent on the ionic strength of the buffer; decreasing with increasing concentration. The pH optimum was around 7, which is lower than pH-optima d...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739109179262
更新日期:1991-01-01 00:00:00
abstract::Ventilation with decelerating inspiratory flow is known to reduce the dead space fraction and to decrease PaCO2. Constant inspiratory flow with an end-inspiratory pause (EIP) is also known to increase the removal of CO2. The aim of the study was to elucidate the effect of the pause/no-flow period while both the patter...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1517/03009734000000044
更新日期:2000-01-01 00:00:00
abstract::Different pharmacokinetic models for target controlled infusion (TCI) of propofol are available in the recently launched open TCI systems. There is also a compelling choice to work with either plasma- or effect-site targets. Knowledge about the clinical consequences of different alternatives is of importance. We aimed...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-222
更新日期:2008-01-01 00:00:00
abstract::Despite the fact that the composition of urine varies a lot during the day, this has essentially been neglected as a factor of importance in determinations of urine bicarbonate. The investigations reviewed in combination with an own study shows that qualitative and quantitative factors in urine composition impacts the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178420
更新日期:1982-01-01 00:00:00
abstract::The effect of implantable drug delivery systems on computed tomography (CT) and magnetic resonance imaging (MRI) was investigated in a phantom and in two patients. The implantable systems of identical construction consisted either of medical grade titanium alloy or stainless steel. Images of a phantom showed artefacts...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738909178560
更新日期:1989-01-01 00:00:00
abstract::Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of < 0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels d...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-068
更新日期:2005-01-01 00:00:00
abstract::Two female patients, 63 and 78 years of age, underwent femoropopliteal bypass with polytetrafluoroethylene (PTFE) graft and distal vein cuff. They developed graft occlusion due to false aneurysm at the site of vein cuff during one and eight weeks after surgery, respectively. Improper suture technique or weak vein wall...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-178
更新日期:2000-01-01 00:00:00
abstract::The tubuloglomerular feedback mechanism is highly activated in juxtamedullary nephrons and considered to play a major role in intrarenal regulation of glomerular filtration rate. The vasculature of juxtamedullary nephrons is highly vasoreactive with a high ability for vasodilation. This vasoreactivity is a prerequisit...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739209179287
更新日期:1992-01-01 00:00:00
abstract::A method for estimation of the erythrocyte sedimentation from repeated measurements during the initial part of the sedimentation phase is described. Based on the measurements between 18 and 24 minutes after the beginning of the reaction, the sedimentation at 60 minutes is estimated. The estimate is highly correlated t...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739409179362
更新日期:1994-01-01 00:00:00
abstract::In 2 monkeys of the species Macaca fascicularis the three dorsal column nuclei and the lateral cervical nucleus have been investigated immunocytochemically with antiserum against Substance P. The Substance P labeling was widely spread but rather sparse. It occurred in small structures of the size of boutons in the gra...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738909178557
更新日期:1989-01-01 00:00:00
abstract::Vasospastic reactions to cold have been suggested to be related to altered blood rheology, as has been reported in both primary (PVD) and traumatic (TVD) vasospastic disease. Measurements of whole blood viscosity, plasma viscosity, erythrocyte deformability and finger systolic pressure (FSP) were performed in 18 patie...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178639
更新日期:1985-01-01 00:00:00
abstract::Radical surgery for renal cancer with invasion of the inferior vena cava can improve the patient's quality of life and, in some cases, offer longer survival or even cure. With a carefully planned surgical approach it is possible to remove renal tumours with thrombotic extension to the most proximal part of the inferio...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178646
更新日期:1985-01-01 00:00:00
abstract:AIM:To investigate how individuals fulfilling the Rome II criteria for irritable bowel syndrome (IBS) spontaneously described their symptoms. METHOD:From a general population, 1,244 randomly sampled adults were asked to describe their gastrointestinal symptoms (if any) verbally, in their own words, at a semi-structure...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2015.1040529
更新日期:2015-01-01 00:00:00
abstract::Antimicrobial susceptibility testing with phenotypic methods requires breakpoints, i.e. a minimum inhibitory concentration (MIC) categorizing micro-organisms into susceptible, intermediately susceptible, and resistant for the relevant antimicrobial agent. Determinations of breakpoints require tools such as the underst...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2014.901446
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Accumulating evidence suggests that enhanced inflammatory responses contribute to the pathogenesis of postoperative cognitive dysfunction (POCD). Blood transfusion can trigger an enhancement of acute inflammatory responses. Therefore, we hypothesized that perioperative blood transfusion is associated with ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.873502
更新日期:2014-08-01 00:00:00
abstract::Glucagon from the pancreatic α-cells is a major blood glucose-regulating hormone whose most important role is to prevent hypoglycaemia that can be life-threatening due to the brain's strong dependence on glucose as energy source. Lack of blood glucose-lowering insulin after malfunction or autoimmune destruction of the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2016.1154905
更新日期:2016-05-01 00:00:00
abstract::This paper discusses briefly: analytical quality and its determinants; design of quality assurance procedures on the basis of quality; specifications and quality-cost models; test quality and medical costs; external quality assessment and harmonization of clinical chemical test results; the potential role of computers...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738609178519
更新日期:1986-01-01 00:00:00
abstract::By means of an accurate immunoenzymatic assay, the prevalence was studied of antibodies to hepatitis C virus (HCV) in three different populations: 74 patients affected with hepatocellular carcinoma (HCC) on preexisting cirrhosis, 82 patients with liver cirrhosis but with no apparent neoplasm, and 70 control subjects, ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739209179300
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Fluid overload is associated with mortality in haemodialysis patients, and 30% of patients remain fluid-overloaded after dialysis. The aim of this study was to evaluate if implementation of Recova®, a decision aid combining clinical assessment with bioimpedance spectroscopy, facilitates individualization of ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2020.1804495
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Diabetic patients exhibit platelet hyperreactivity, which renders them resistant to antithrombotic treatments. We aimed to investigate the prevalence and predictors of aspirin resistance in diabetic patients. MATERIAL AND METHODS:A total of 93 diabetic and 37 non-diabetic participants were included into the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.861549
更新日期:2014-03-01 00:00:00
abstract::The vertebral end-plates and the epiphyses from the lumbar region of the spine in juvenile pigs were studied. Cell density of the hyaline cartilage of the vertebral bodies was measured as well as cartilage thickness. The relative bone content in the region of the nucleus pulposus was calculated. A certain negative int...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178481
更新日期:1985-01-01 00:00:00
abstract::The purpose of this study is to verify that compound muscle action potentials (CMAPs) generated a stationary potential and to examine extension of the CMAPs away from the stimulated muscle. A referential derivation and/or bipolar derivation to record the stationary potentials were carried out following tibial nerve st...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-103
更新日期:2004-01-01 00:00:00
abstract::Determinations were made of the 2-hour 22Na space and the 1 and 2 hour 51Cr EDTA spaces in a number of tissues. In regions where the two 51Cr-EDTA spaces were similar and smaller than or similar to the 22Na space the former spaces were regarded as measures of the extra-cellular volume. Using previously published data ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737909179148
更新日期:1979-01-01 00:00:00
abstract::Factors that may influence the water transport through the skin in infants on their first day of life were studied with a method based on determination of the vapour pressure gradient in the air layer close to the skin surface. The evaporation rate from the skin was found to vary with the site of measurement, ambient ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179207
更新日期:1981-01-01 00:00:00
abstract::Transforming growth factor-β (TGF-β) elicits both tumor-suppressive and tumor-promoting functions during cancer progression. Here, we describe the tumor-promoting functions of TGF-β and how these functions play a role in cancer progression. Normal epithelial cells undergo epithelial-mesenchymal transition (EMT) throug...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2011.638729
更新日期:2012-05-01 00:00:00
abstract::We herein outline the rationale for a Swedish cohort consortium, aiming to facilitate greater use of Swedish cohorts for world-class research. Coordination of all Swedish prospective population-based cohorts in a common infrastructure would enable more precise research findings and facilitate research on rare exposure...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2018.1556754
更新日期:2019-01-01 00:00:00
abstract::Fifty-one healthy men, 18 - 19 years of age, with "organic" T wave aberrations (group T) were compared to 112 controls of the same age with normal electrocardiograms (Group A + B). Group T had increased heart rate and higher systolic and diastolic blood pressures. Their lower physical work capacity could be "explained...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179186
更新日期:1980-01-01 00:00:00