Predicting Antidepressant Citalopram Treatment Response via Changes in Brain Functional Connectivity After Acute Intravenous Challenge.

abstract：:Despite an abundance of computational models for learning of synaptic weights, there has been relatively little research on structural plasticity, i.e., the creation and elimination of synapses. Especially, it is not clear how structural plasticity works in concert with spike-timing-dependent plasticity (STDP) and wha...

journal_title：Frontiers in computational neuroscience

authors： Spiess R,George R,Cook M,Diehl PU

更新日期：2016-09-08 00:00:00

abstract：:The output of primary visual cortex (V1) is a piecemeal representation of the visual scene and the response of any one cell cannot unambiguously guide sensorimotor behavior. It remains unsolved how subsequent stages of cortical processing combine ("pool") these early visual signals into a coherent representation. We (...

journal_title：Frontiers in computational neuroscience

authors： Rocchi F,Ledgeway T,Webb BS

更新日期：2013-11-18 00:00:00

abstract：:The human brain is a complex system composed by several large scale intrinsic networks with distinct functions. The low frequency oscillation (LFO) signal of blood oxygen level dependent (BOLD), measured through resting-state fMRI, reflects the spontaneous neural activity of these networks. We propose to characterize ...

journal_title：Frontiers in computational neuroscience

authors： Qi S,Gao Q,Shen J,Teng Y,Xie X,Sun Y,Wu J

更新日期：2018-08-03 00:00:00

abstract：:Previous studies have shown that the auditory cortex can enhance the perception of behaviorally important sounds in the presence of background noise, but the mechanisms by which it does this are not yet elucidated. Rapid plasticity of spectrotemporal receptive fields (STRFs) in the primary (A1) cortical neurons is obs...

journal_title：Frontiers in computational neuroscience

authors： Chambers JD,Elgueda D,Fritz JB,Shamma SA,Burkitt AN,Grayden DB

更新日期：2019-05-24 00:00:00

abstract：:Common computational principles underlie processing of various visual features in the cortex. They are considered to create similar patterns of contextual modulations in behavioral studies for different features as orientation and direction of motion. Here, I studied the possibility that a single theoretical framework...

journal_title：Frontiers in computational neuroscience

authors： Tzvetanov T

更新日期：2012-05-22 00:00:00

abstract：:We do not claim that the brain is completely deterministic, and we agree that noise may be beneficial in some cases. But we suggest that neuronal variability may be often overestimated, due to uncontrolled internal variables, and/or the use of inappropriate reference times. These ideas are not new, but should be re-ex...

journal_title：Frontiers in computational neuroscience

authors： Masquelier T

更新日期：2013-02-25 00:00:00

abstract：:Predictive coding appears to be one of the fundamental working principles of brain processing. Amongst other aspects, brains often predict the sensory consequences of their own actions. Predictive coding resembles Kalman filtering, where incoming sensory information is filtered to produce prediction errors for subsequ...

journal_title：Frontiers in computational neuroscience

authors： Kneissler J,Drugowitsch J,Friston K,Butz MV

更新日期：2015-04-30 00:00:00

abstract：:We often encounter pairs of variables in the world whose mutual relationship can be described by a function. After training, human responses closely correspond to these functional relationships. Here we study how humans predict unobserved segments of a function that they have been trained on and we compare how human p...

journal_title：Frontiers in computational neuroscience

authors： Narain D,Smeets JB,Mamassian P,Brenner E,van Beers RJ

更新日期：2014-09-30 00:00:00

abstract：:The cerebellum is known to play a critical role in learning relevant patterns of activity for adaptive motor control, but the underlying network mechanisms are only partly understood. The classical long-term synaptic plasticity between parallel fibers (PFs) and Purkinje cells (PCs), which is driven by the inferior oli...

journal_title：Frontiers in computational neuroscience

authors： Luque NR,Garrido JA,Carrillo RR,D'Angelo E,Ros E

更新日期：2014-08-15 00:00:00

abstract：:The extent to which groups of neurons exhibit higher-order correlations in their spiking activity is a controversial issue in current brain research. A major difficulty is that currently available tools for the analysis of massively parallel spike trains (N >10) for higher-order correlations typically require vast sam...

journal_title：Frontiers in computational neuroscience

authors： Staude B,Grün S,Rotter S

更新日期：2010-07-02 00:00:00

abstract：:In this paper we investigate the active inference framework as a means to enable autonomous behavior in artificial agents. Active inference is a theoretical framework underpinning the way organisms act and observe in the real world. In active inference, agents act in order to minimize their so called free energy, or p...

journal_title：Frontiers in computational neuroscience

authors： Çatal O,Wauthier S,De Boom C,Verbelen T,Dhoedt B

更新日期：2020-11-16 00:00:00

abstract：:Synchronization of neural activity across brain regions is critical to processes that include perception, learning, and memory. After traumatic brain injury (TBI), neuronal degeneration is one possible effect and can alter communication between neural circuits. Consequently, synchronization between neurons may change ...

journal_title：Frontiers in computational neuroscience

authors： Schumm SN,Gabrieli D,Meaney DF

更新日期：2020-03-03 00:00:00

abstract：:This paper presents a new model-based method to define muscle synergies. Unlike the conventional factorization approach, which extracts synergies from electromyographic data, the proposed method employs a biomechanical model and formally defines the synergies as the solution of an optimal control problem. As a result,...

journal_title：Frontiers in computational neuroscience

authors： Sharif Razavian R,Mehrabi N,McPhee J

更新日期：2015-10-06 00:00:00

abstract：:Drosophila larvae crawl by peristaltic waves of muscle contractions, which propagate along the animal body and involve the simultaneous contraction of the left and right side of each segment. Coordinated propagation of contraction does not require sensory input, suggesting that movement is generated by a central patte...

journal_title：Frontiers in computational neuroscience

authors： Gjorgjieva J,Berni J,Evers JF,Eglen SJ

更新日期：2013-04-04 00:00:00

abstract：:Recently, biologically inspired models are gradually proposed to solve the problem in text analysis. Convolutional neural networks (CNN) are hierarchical artificial neural networks, which include a various of multilayer perceptrons. According to biological research, CNN can be improved by bringing in the attention mod...

journal_title：Frontiers in computational neuroscience

authors： Fu H,Niu Z,Zhang C,Ma J,Chen J

更新日期：2016-07-14 00:00:00

abstract：:We present a phenomenological model of electrically stimulated auditory nerve fibers (ANFs). The model reproduces the probabilistic and temporal properties of the ANF response to both monophasic and biphasic stimuli, in isolation. The main contribution of the model lies in its ability to reproduce statistics of the AN...

journal_title：Frontiers in computational neuroscience

authors： Horne CD,Sumner CJ,Seeber BU

更新日期：2016-02-08 00:00:00

abstract：:Obtaining good quality image features is of remarkable importance for most computer vision tasks. It has been demonstrated that the first layers of the human visual cortex are devoted to feature detection. The need for these features has made line, segment, and corner detection one of the most studied topics in comput...

journal_title：Frontiers in computational neuroscience

authors： Bachiller-Burgos P,Manso LJ,Bustos P

更新日期：2018-06-01 00:00:00

abstract：:With the emergence of online publishing, opportunities to maximize transparency of scientific research have grown considerably. However, these possibilities are still only marginally used. We argue for the implementation of (1) peer-reviewed peer review, (2) transparent editorial hierarchies, and (3) online data publi...

journal_title：Frontiers in computational neuroscience

authors： Wicherts JM,Kievit RA,Bakker M,Borsboom D

更新日期：2012-04-03 00:00:00

abstract：:The muscle synergy hypothesis assumes that individual muscle synergies are independent of each other and voluntarily controllable. However, this assumption has not been empirically tested. This study tested if human subjects can voluntarily activate individual muscle synergies extracted by non-negative matrix factoriz...

journal_title：Frontiers in computational neuroscience

authors： Togo S,Imamizu H

更新日期：2017-09-06 00:00:00

abstract：:Astrocytes actively shape the dynamics of neurons and neuronal ensembles by affecting several aspects critical to neuronal function, such as regulating synaptic plasticity, modulating neuronal excitability, and maintaining extracellular ion balance. These pathways for astrocyte-neuron interaction can also enhance the ...

journal_title：Frontiers in computational neuroscience

authors： Volman V,Bazhenov M,Sejnowski TJ

更新日期：2012-08-13 00:00:00

abstract：:This paper investigates how a neural network model of the ventral visual pathway, VisNet, can form separate view invariant representations of a number of objects seen rotating together. In particular, in the current work one of the rotating objects is always partially occluded by the other objects present during train...

journal_title：Frontiers in computational neuroscience

authors： Tromans JM,Higgins I,Stringer SM

更新日期：2012-07-25 00:00:00

abstract：:We address a question on the effect of common stochastic inputs on the correlation of the spike trains of two neurons when they are coupled through direct connections. We show that the change in the correlation of small amplitude stochastic inputs can be better detected when the neurons are connected by direct excitat...

journal_title：Frontiers in computational neuroscience

authors： Bolhasani E,Azizi Y,Valizadeh A

更新日期：2013-08-14 00:00:00

abstract：:Many brain regions communicate information through synchronized network activity. Electrical coupling among the dendrites of interneurons in the cortex has been implicated in forming and sustaining such activity in the cortex. Evidence for the existence of electrical coupling among cortical pyramidal cells, however, h...

journal_title：Frontiers in computational neuroscience

authors： Crodelle J,Zhou D,Kovačič G,Cai D

更新日期：2019-05-28 00:00:00

abstract：:Many of the synapses in the basal ganglia display short-term plasticity. Still, computational models have not yet been used to investigate how this affects signaling. Here we use a model of the basal ganglia network, constrained by available data, to quantitatively investigate how synaptic short-term plasticity affect...

journal_title：Frontiers in computational neuroscience

authors： Lindahl M,Kamali Sarvestani I,Ekeberg O,Kotaleski JH

更新日期：2013-06-19 00:00:00

abstract：:Two important stimulus features represented within the rodent barrel cortex are velocity and angular direction of whisker deflection. Each cortical barrel receives information from thalamocortical (TC) cells that relay information from a single whisker, and TC input is decoded by barrel regular-spiking (RS) cells thro...

journal_title：Frontiers in computational neuroscience

authors： Patel MJ

更新日期：2018-06-12 00:00:00

abstract：:In order to be able to examine the extracellular potential's influence on network activity and to better understand dipole properties of the extracellular potential, we present and analyze a three-dimensional formulation of the cable equation which facilitates numeric simulations. When the neuron's intra- and extracel...

journal_title：Frontiers in computational neuroscience

authors： Xylouris K,Wittum G

更新日期：2015-07-17 00:00:00

abstract：:Neuron encodes and transmits information through generating sequences of output spikes, which is a high energy-consuming process. The spike is initiated when membrane depolarization reaches a threshold voltage. In many neurons, threshold is dynamic and depends on the rate of membrane depolarization (dV/dt) preceding a...

journal_title：Frontiers in computational neuroscience

authors： Yi GS,Wang J,Tsang KM,Wei XL,Deng B

更新日期：2015-05-27 00:00:00

abstract：:The mechanisms underlying electrophysiologically observed two-way transitions between absence and tonic-clonic epileptic seizures in cerebral cortex remain unknown. The interplay within thalamocortical network is believed to give rise to these epileptic multiple modes of activity and transitions between them. In parti...

journal_title：Frontiers in computational neuroscience

authors： Fan D,Duan L,Wang Q,Luan G

更新日期：2017-07-07 00:00:00

abstract：:Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To investigate the interac...

journal_title：Frontiers in computational neuroscience

authors： Kim H,Heckman CJ

更新日期：2014-09-09 00:00:00

abstract：:Modern machine learning is based on powerful algorithms running on digital computing platforms and there is great interest in accelerating the learning process and making it more energy efficient. In this paper we present a fully autonomous probabilistic circuit for fast and efficient learning that makes no use of dig...

journal_title：Frontiers in computational neuroscience

authors： Kaiser J,Faria R,Camsari KY,Datta S

更新日期：2020-02-25 00:00:00