A three-dimensional mathematical model for the signal propagation on a neuron's membrane.

abstract：:In synapses, calcium is required for modulating synaptic transmission, plasticity, synaptogenesis, and synaptic pruning. The regulation of calcium dynamics within neurons involves cellular mechanisms such as synaptically activated channels and pumps, calcium buffers, and calcium sequestrating organelles. Many experime...

journal_title：Frontiers in computational neuroscience

authors： Hu E,Mergenthal A,Bingham CS,Song D,Bouteiller JM,Berger TW

更新日期：2018-07-27 00:00:00

abstract：:Animals try to make sense of sensory information from multiple modalities by categorizing them into perceptions of individual or multiple external objects or internal concepts. For example, the brain constructs sensory, spatial representations of the locations of visual and auditory stimuli in the visual and auditory ...

journal_title：Frontiers in computational neuroscience

authors： Daemi M,Harris LR,Crawford JD

更新日期：2016-06-23 00:00:00

abstract：:Previous studies have shown that the auditory cortex can enhance the perception of behaviorally important sounds in the presence of background noise, but the mechanisms by which it does this are not yet elucidated. Rapid plasticity of spectrotemporal receptive fields (STRFs) in the primary (A1) cortical neurons is obs...

journal_title：Frontiers in computational neuroscience

authors： Chambers JD,Elgueda D,Fritz JB,Shamma SA,Burkitt AN,Grayden DB

更新日期：2019-05-24 00:00:00

abstract：:A classic problem in neuroscience is how temporal sequences (TSs) can be recognized. This problem is exemplified in the olfactory system, where an odor is defined by the TS of olfactory bulb (OB) output that occurs during a sniff. This sequence is discrete because the output is subdivided by gamma frequency oscillatio...

journal_title：Frontiers in computational neuroscience

authors： Sanders H,Kolterman BE,Shusterman R,Rinberg D,Koulakov A,Lisman J

更新日期：2014-09-17 00:00:00

abstract：:For large-scale network simulations, it is often desirable to have computationally tractable, yet in a defined sense still physiologically valid neuron models. In particular, these models should be able to reproduce physiological measurements, ideally in a predictive sense, and under different input regimes in which n...

journal_title：Frontiers in computational neuroscience

authors： Hertäg L,Hass J,Golovko T,Durstewitz D

更新日期：2012-09-06 00:00:00

abstract：:Networks with continuous set of attractors are considered to be a paradigmatic model for parametric working memory (WM), but require fine tuning of connections and are thus structurally unstable. Here we analyzed the network with ring attractor, where connections are not perfectly tuned and the activity state therefor...

journal_title：Frontiers in computational neuroscience

authors： Itskov V,Hansel D,Tsodyks M

更新日期：2011-10-24 00:00:00

abstract：:Probabilistic models of decision making under various forms of uncertainty have been applied in recent years to numerous behavioral and model-based fMRI studies. These studies were highly successful in enabling a better understanding of behavior and delineating the functional properties of brain areas involved in deci...

journal_title：Frontiers in computational neuroscience

authors： Marković D,Kiebel SJ

更新日期：2016-04-20 00:00:00

abstract：:Calcium concentrations as well as time courses have been used to model the signaling cascades leading to changes in the strength of synaptic connections. Previous models consider the dendritic spines as uniform compartments regarding calcium signaling. However, calcium concentrations can vary drastically on distances ...

journal_title：Frontiers in computational neuroscience

authors： Mihalas S

更新日期：2011-01-13 00:00:00

abstract：:The phase-reset model of oscillatory EEG activity has received a lot of attention in the last decades for decoding different cognitive processes. Based on this model, the ERPs are assumed to be generated as a result of phase reorganization in ongoing EEG. Alignment of the phase of neuronal activities can be observed w...

journal_title：Frontiers in computational neuroscience

authors： Mortezapouraghdam Z,Corona-Strauss FI,Takahashi K,Strauss DJ

更新日期：2018-10-08 00:00:00

abstract：:Often we need to perform tasks in an environment that changes stochastically. In these situations it is important to learn the statistics of sequences of events in order to predict the future and the outcome of our actions. The statistical description of many of these sequences can be reduced to the set of probabiliti...

journal_title：Frontiers in computational neuroscience

authors： Ostojic S,Fusi S

更新日期：2013-04-12 00:00:00

abstract：:What are the functional neuroimaging measurements required for more fully characterizing the events and locations of neocortical activity? A prime assumption has been that modulation of cortical activity will inevitably be reflected in changes in energy utilization (for the most part) changes of glucose and oxygen con...

journal_title：Frontiers in computational neuroscience

authors： Robinson SE,Mandell AJ,Coppola R

更新日期：2013-01-24 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder which follows from cell loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), a nucleus in the basal ganglia (BG). Deep brain stimulation (DBS) is an electrical therapy that modulates the pathological activity to treat the motor symptoms of P...

journal_title：Frontiers in computational neuroscience

authors： Summerson SR,Aazhang B,Kemere C

更新日期：2015-06-26 00:00:00

abstract：:Predictive coding hypothesizes that the brain explicitly infers upcoming sensory input to establish a coherent representation of the world. Although it is becoming generally accepted, it is not clear on which level spiking neural networks may implement predictive coding and what function their connectivity may have. W...

journal_title：Frontiers in computational neuroscience

authors： Kaplan BA,Lansner A,Masson GS,Perrinet LU

更新日期：2013-09-17 00:00:00

abstract：:In this paper we investigate the active inference framework as a means to enable autonomous behavior in artificial agents. Active inference is a theoretical framework underpinning the way organisms act and observe in the real world. In active inference, agents act in order to minimize their so called free energy, or p...

journal_title：Frontiers in computational neuroscience

authors： Çatal O,Wauthier S,De Boom C,Verbelen T,Dhoedt B

更新日期：2020-11-16 00:00:00

abstract：:A wide range of blind source separation methods have been used in motor control research for the extraction of movement primitives from EMG and kinematic data. Popular examples are principal component analysis (PCA), independent component analysis (ICA), anechoic demixing, and the time-varying synergy model (d'Avella ...

journal_title：Frontiers in computational neuroscience

authors： Endres DM,Chiovetto E,Giese MA

更新日期：2013-12-20 00:00:00

abstract：:Our aim is to propose an efficient algorithm for enhancing the contrast of dark images based on the principle of stochastic resonance in a global feedback spiking network of integrate-and-fire neurons. By linear approximation and direct simulation, we disclose the dependence of the peak signal-to-noise ratio on the sp...

journal_title：Frontiers in computational neuroscience

authors： Fu Y,Kang Y,Chen G

更新日期：2020-05-15 00:00:00

abstract：:We present a network model of striatum, which generates "winnerless" dynamics typical for a network of sparse, unidirectionally connected inhibitory units. We observe that these dynamics, while interesting and a good match to normal striatal electrophysiological recordings, are fragile. Specifically, we find that rand...

journal_title：Frontiers in computational neuroscience

authors： Zheng P,Kozloski J

更新日期：2017-07-27 00:00:00

abstract：:Despite an abundance of computational models for learning of synaptic weights, there has been relatively little research on structural plasticity, i.e., the creation and elimination of synapses. Especially, it is not clear how structural plasticity works in concert with spike-timing-dependent plasticity (STDP) and wha...

journal_title：Frontiers in computational neuroscience

authors： Spiess R,George R,Cook M,Diehl PU

更新日期：2016-09-08 00:00:00

abstract：:Objective: To study the effect of directional deep brain stimulation (DBS) electrode configuration and vertical electrode spacing on the volume of tissue activated (VTA) in the globus pallidus, pars interna (GPi). Background: Directional DBS leads may allow clinicians to precisely direct current fields to different fu...

journal_title：Frontiers in computational neuroscience

authors： Zhang S,Tagliati M,Pouratian N,Cheeran B,Ross E,Pereira E

更新日期：2020-09-25 00:00:00

abstract：:Introduction: The early and therapy-specific prediction of treatment success in major depressive disorder is of paramount importance due to high lifetime prevalence, and heterogeneity of response to standard medication and symptom expression. Hence, this study assessed the predictability of long-term antidepressant ef...

journal_title：Frontiers in computational neuroscience

authors： Klöbl M,Gryglewski G,Rischka L,Godbersen GM,Unterholzner J,Reed MB,Michenthaler P,Vanicek T,Winkler-Pjrek E,Hahn A,Kasper S,Lanzenberger R

更新日期：2020-10-06 00:00:00

abstract：:Proprioceptive afferents from muscle spindles encode information about peripheral joint movements for the central nervous system (CNS). The sensitivity of muscle spindle is nonlinearly dependent on the activation of gamma (γ) motoneurons in the spinal cord that receives inputs from the motor cortex. How fusimotor cont...

journal_title：Frontiers in computational neuroscience

authors： Lan N,He X

更新日期：2012-08-30 00:00:00

abstract：:Single-unit measurements have reported many different effects of attention on contrast-response (e.g., contrast-gain, response-gain, additive-offset dependent on visibility), while functional imaging measurements have more uniformly reported increases in response across all contrasts (additive-offset). The normalizati...

journal_title：Frontiers in computational neuroscience

authors： Hara Y,Pestilli F,Gardner JL

更新日期：2014-02-19 00:00:00

abstract：:We present a phenomenological model of electrically stimulated auditory nerve fibers (ANFs). The model reproduces the probabilistic and temporal properties of the ANF response to both monophasic and biphasic stimuli, in isolation. The main contribution of the model lies in its ability to reproduce statistics of the AN...

journal_title：Frontiers in computational neuroscience

authors： Horne CD,Sumner CJ,Seeber BU

更新日期：2016-02-08 00:00:00

abstract：:The mechanisms underlying electrophysiologically observed two-way transitions between absence and tonic-clonic epileptic seizures in cerebral cortex remain unknown. The interplay within thalamocortical network is believed to give rise to these epileptic multiple modes of activity and transitions between them. In parti...

journal_title：Frontiers in computational neuroscience

authors： Fan D,Duan L,Wang Q,Luan G

更新日期：2017-07-07 00:00:00

abstract：:To understand the function of the neocortex, which is a hierarchical distributed network, it is useful giving meaning to the signals transmitted between these areas from the computational viewpoint. The overall anatomical structure or organs related to this network, including the neocortex, thalamus, and basal ganglia...

journal_title：Frontiers in computational neuroscience

authors： Yamakawa H

更新日期：2020-08-18 00:00:00

abstract：:The process of conditioning via reward learning is highly relevant to the study of food choice and obesity. Learning is itself shaped by environmental exposure, with the potential for such exposures to vary substantially across individuals and across place and time. In this paper, we use computational techniques to ex...

journal_title：Frontiers in computational neuroscience

authors： Hammond RA,Ornstein JT,Fellows LK,Dubé L,Levitan R,Dagher A

更新日期：2012-10-11 00:00:00

abstract：:The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences i...

journal_title：Frontiers in computational neuroscience

authors： Lei X,Han Z,Chen C,Bai L,Xue G,Dong Q

更新日期：2016-09-23 00:00:00

abstract：:Dopaminergic neurons in the mammalian substantia nigra display characteristic phasic responses to stimuli which reliably predict the receipt of primary rewards. These responses have been suggested to encode reward prediction-errors similar to those used in reinforcement learning. Here, we propose a model of dopaminerg...

journal_title：Frontiers in computational neuroscience

authors： Chorley P,Seth AK

更新日期：2011-05-18 00:00:00

abstract：:Affective human-robot interaction requires lightweight software and cheap wearable devices that could further this field. However, the estimation of emotions in real-time poses a problem that has not yet been optimized. An optimization is proposed for the emotion estimation methodology including artifact removal, feat...

journal_title：Frontiers in computational neuroscience

authors： Val-Calvo M,Álvarez-Sánchez JR,Ferrández-Vicente JM,Fernández E

更新日期：2019-11-26 00:00:00

abstract：:Common computational principles underlie processing of various visual features in the cortex. They are considered to create similar patterns of contextual modulations in behavioral studies for different features as orientation and direction of motion. Here, I studied the possibility that a single theoretical framework...

journal_title：Frontiers in computational neuroscience

authors： Tzvetanov T

更新日期：2012-05-22 00:00:00