Neuromodulation impact on nonlinear firing behavior of a reduced model motoneuron with the active dendrite.

abstract：:The inverse problem for estimating model parameters from brain spike data is an ill-posed problem because of a huge mismatch in the system complexity between the model and the brain as well as its non-stationary dynamics, and needs a stochastic approach that finds the most likely solution among many possible solutions...

journal_title：Frontiers in computational neuroscience

authors： Hoang H,Yamashita O,Tokuda IT,Sato MA,Kawato M,Toyama K

更新日期：2015-05-21 00:00:00

abstract：:Persistent activity observed during delayed-response tasks for spatial working memory (Funahashi et al., 1989) has commonly been modeled by recurrent networks whose dynamics is described as a bump attractor (Compte et al., 2000). We examine the effects of interareal architecture on the dynamics of bump attractors in s...

journal_title：Frontiers in computational neuroscience

authors： Kilpatrick ZP

更新日期：2013-07-01 00:00:00

abstract：:Synchronization of neural activity across brain regions is critical to processes that include perception, learning, and memory. After traumatic brain injury (TBI), neuronal degeneration is one possible effect and can alter communication between neural circuits. Consequently, synchronization between neurons may change ...

journal_title：Frontiers in computational neuroscience

authors： Schumm SN,Gabrieli D,Meaney DF

更新日期：2020-03-03 00:00:00

abstract：:We describe a model for cortical development that resolves long-standing difficulties of earlier models. It is proposed that, during embryonic development, synchronous firing of neurons and their competition for limited metabolic resources leads to selection of an array of neurons with ultra-small-world characteristic...

journal_title：Frontiers in computational neuroscience

authors： Wright JJ,Bourke PD

更新日期：2013-02-15 00:00:00

abstract：:The problem of cancer risk analysis is of great importance to health-service providers and medical researchers. In this study, we propose a novel Artificial Neural Network (ANN) algorithm based on the probabilistic framework, which aims to investigate patient patterns associated with their disease development. Compare...

journal_title：Frontiers in computational neuroscience

authors： Yang C,Yang J,Liu Y,Geng X

更新日期：2020-07-21 00:00:00

abstract：:VISUAL RECEPTIVE FIELD (RF) ATTRIBUTES IN VISUAL CORTEX OF PRIMATES HAVE BEEN EXPLAINED MAINLY FROM CORTICAL CONNECTIONS: visual RFs progress from simple to complex through cortico-cortical pathways from lower to higher levels in the visual hierarchy. This feedforward flow of information is paired with top-down proces...

journal_title：Frontiers in computational neuroscience

authors： Cortes N,van Vreeswijk C

更新日期：2012-05-28 00:00:00

abstract：:Motor system uses muscle synergies as a modular organization to simplify the control of movements. Motor cortical impairments, such as stroke and spinal cord injuries, disrupt the orchestration of the muscle synergies and result in abnormal movements. In this paper, the alterations of muscle synergies in subacute stro...

journal_title：Frontiers in computational neuroscience

authors： Pan B,Sun Y,Xie B,Huang Z,Wu J,Hou J,Liu Y,Huang Z,Zhang Z

更新日期：2018-08-21 00:00:00

abstract：:Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA m...

journal_title：Frontiers in computational neuroscience

authors： Adamchik DA,Matrosov VV,Kazantsev VB

更新日期：2018-04-05 00:00:00

abstract：:The emergence of motion sensors as a tool that provides objective motor performance data on individuals afflicted with Parkinson's disease offers an opportunity to expand the horizon of clinical care for this neurodegenerative condition. Subjective clinical scales and patient based motor diaries have limited clinometr...

journal_title：Frontiers in computational neuroscience

authors： Ramdhani RA,Khojandi A,Shylo O,Kopell BH

更新日期：2018-09-11 00:00:00

abstract：:Single-unit measurements have reported many different effects of attention on contrast-response (e.g., contrast-gain, response-gain, additive-offset dependent on visibility), while functional imaging measurements have more uniformly reported increases in response across all contrasts (additive-offset). The normalizati...

journal_title：Frontiers in computational neuroscience

authors： Hara Y,Pestilli F,Gardner JL

更新日期：2014-02-19 00:00:00

abstract：:Cortical neurons are typically driven by several thousand synapses. The precise spatiotemporal pattern formed by these inputs can modulate the response of a post-synaptic cell. In this work, we explore how the temporal structure of pre-synaptic inhibitory and excitatory inputs impact the post-synaptic firing of a cond...

journal_title：Frontiers in computational neuroscience

authors： Scheller B,Castellano M,Vicente R,Pipa G

更新日期：2011-12-16 00:00:00

abstract：:Sensitivity analysis can provide useful information when one is interested in identifying the parameter θ of a system since it measures the variations of the output u when θ changes. In the literature two different sensitivity functions are frequently used: the traditional sensitivity functions (TSF) and the generaliz...

journal_title：Frontiers in computational neuroscience

authors： Troparevsky MI,Rubio D,Saintier N

更新日期：2010-09-30 00:00:00

abstract：:We do not claim that the brain is completely deterministic, and we agree that noise may be beneficial in some cases. But we suggest that neuronal variability may be often overestimated, due to uncontrolled internal variables, and/or the use of inappropriate reference times. These ideas are not new, but should be re-ex...

journal_title：Frontiers in computational neuroscience

authors： Masquelier T

更新日期：2013-02-25 00:00:00

abstract：:Affective human-robot interaction requires lightweight software and cheap wearable devices that could further this field. However, the estimation of emotions in real-time poses a problem that has not yet been optimized. An optimization is proposed for the emotion estimation methodology including artifact removal, feat...

journal_title：Frontiers in computational neuroscience

authors： Val-Calvo M,Álvarez-Sánchez JR,Ferrández-Vicente JM,Fernández E

更新日期：2019-11-26 00:00:00

abstract：:Short-term synaptic plasticity is highly diverse across brain area, cortical layer, cell type, and developmental stage. Since short-term plasticity (STP) strongly shapes neural dynamics, this diversity suggests a specific and essential role in neural information processing. Therefore, a correct characterization of sho...

journal_title：Frontiers in computational neuroscience

authors： Costa RP,Sjöström PJ,van Rossum MC

更新日期：2013-06-06 00:00:00

abstract：:Common computational principles underlie processing of various visual features in the cortex. They are considered to create similar patterns of contextual modulations in behavioral studies for different features as orientation and direction of motion. Here, I studied the possibility that a single theoretical framework...

journal_title：Frontiers in computational neuroscience

authors： Tzvetanov T

更新日期：2012-05-22 00:00:00

abstract：:The role of dendritic spiking mechanisms in neural processing is so far poorly understood. To investigate the role of calcium spikes in the functional properties of the single neuron and recurrent networks, we investigated a three compartment neuron model of the layer 5 pyramidal neuron with calcium dynamics in the di...

journal_title：Frontiers in computational neuroscience

authors： Chua Y,Morrison A

更新日期：2016-07-22 00:00:00

abstract：:Our aim is to propose an efficient algorithm for enhancing the contrast of dark images based on the principle of stochastic resonance in a global feedback spiking network of integrate-and-fire neurons. By linear approximation and direct simulation, we disclose the dependence of the peak signal-to-noise ratio on the sp...

journal_title：Frontiers in computational neuroscience

authors： Fu Y,Kang Y,Chen G

更新日期：2020-05-15 00:00:00

abstract：:The study of sensory signaling in the visual cortex has been greatly advanced by the recording of neural activity simultaneously with the performance of a specific psychophysical task. Individual nerve cells may also increase their firing leading up to the particular choice or decision made on a single psychophysical ...

journal_title：Frontiers in computational neuroscience

authors： Parker AJ

更新日期：2013-08-13 00:00:00

abstract：:Neuronal action potentials or spikes provide a long-range, noise-resistant means of communication between neurons. As point processes single spikes contain little information in themselves, i.e., outside the context of spikes from other neurons. Moreover, they may fail to cross a synapse. A burst, which consists of a ...

journal_title：Frontiers in computational neuroscience

authors： Zeldenrust F,Wadman WJ,Englitz B

更新日期：2018-07-06 00:00:00

abstract：:We often encounter pairs of variables in the world whose mutual relationship can be described by a function. After training, human responses closely correspond to these functional relationships. Here we study how humans predict unobserved segments of a function that they have been trained on and we compare how human p...

journal_title：Frontiers in computational neuroscience

authors： Narain D,Smeets JB,Mamassian P,Brenner E,van Beers RJ

更新日期：2014-09-30 00:00:00

abstract：:The correlation structure of neural activity is believed to play a major role in the encoding and possibly the decoding of information in neural populations. Recently, several methods were developed for exactly controlling the correlation structure of multi-channel synthetic spike trains (Brette, 2009; Krumin and Shoh...

journal_title：Frontiers in computational neuroscience

authors： Krumin M,Reutsky I,Shoham S

更新日期：2010-11-19 00:00:00

abstract：:In this article, we describe and analyze the chaotic behavior of a conductance-based neuronal bursting model. This is a model with a reduced number of variables, yet it retains biophysical plausibility. Inspired by the activity of cold thermoreceptors, the model contains a persistent Sodium current, a Calcium-activate...

journal_title：Frontiers in computational neuroscience

authors： Xu K,Maidana JP,Caviedes M,Quero D,Aguirre P,Orio P

更新日期：2017-03-10 00:00:00

abstract：:The phase-reset model of oscillatory EEG activity has received a lot of attention in the last decades for decoding different cognitive processes. Based on this model, the ERPs are assumed to be generated as a result of phase reorganization in ongoing EEG. Alignment of the phase of neuronal activities can be observed w...

journal_title：Frontiers in computational neuroscience

authors： Mortezapouraghdam Z,Corona-Strauss FI,Takahashi K,Strauss DJ

更新日期：2018-10-08 00:00:00

abstract：:Purpose: This study is to exam self-esteem related brain morphometry on brain magnetic resonance (MR) images using multilevel-features-based classification method. Method: The multilevel region of interest (ROI) features consist of two types of features: (i) ROI features, which include gray matter volume, white matter...

journal_title：Frontiers in computational neuroscience

authors： Peng B,Lu J,Saxena A,Zhou Z,Zhang T,Wang S,Dai Y

更新日期：2017-05-22 00:00:00

abstract：:Relatively recent advances in patch clamp recordings and iontophoresis have enabled unprecedented study of neuronal post-synaptic integration ("dendritic integration"). Findings support a separate layer of integration in the dendritic branches before potentials reach the cell's soma. While integration between branches...

journal_title：Frontiers in computational neuroscience

authors： Singh MF,Zald DH

更新日期：2015-08-10 00:00:00

abstract：:Drosophila larvae crawl by peristaltic waves of muscle contractions, which propagate along the animal body and involve the simultaneous contraction of the left and right side of each segment. Coordinated propagation of contraction does not require sensory input, suggesting that movement is generated by a central patte...

journal_title：Frontiers in computational neuroscience

authors： Gjorgjieva J,Berni J,Evers JF,Eglen SJ

更新日期：2013-04-04 00:00:00

abstract：:Proprioceptive afferents from muscle spindles encode information about peripheral joint movements for the central nervous system (CNS). The sensitivity of muscle spindle is nonlinearly dependent on the activation of gamma (γ) motoneurons in the spinal cord that receives inputs from the motor cortex. How fusimotor cont...

journal_title：Frontiers in computational neuroscience

authors： Lan N,He X

更新日期：2012-08-30 00:00:00

abstract：:Stability is an important dynamical property of complex systems and underpins a broad range of coherent self-organized behavior. Based on evidence that some neurological disorders correspond to linear instabilities, we hypothesize that stability constrains the brain's electrical activity and influences its structure a...

journal_title：Frontiers in computational neuroscience

authors： Gray RT,Robinson PA

更新日期：2013-04-12 00:00:00

abstract：:A classic problem in neuroscience is how temporal sequences (TSs) can be recognized. This problem is exemplified in the olfactory system, where an odor is defined by the TS of olfactory bulb (OB) output that occurs during a sniff. This sequence is discrete because the output is subdivided by gamma frequency oscillatio...

journal_title：Frontiers in computational neuroscience

authors： Sanders H,Kolterman BE,Shusterman R,Rinberg D,Koulakov A,Lisman J

更新日期：2014-09-17 00:00:00