Probabilistic inference of short-term synaptic plasticity in neocortical microcircuits.

abstract：:For large-scale network simulations, it is often desirable to have computationally tractable, yet in a defined sense still physiologically valid neuron models. In particular, these models should be able to reproduce physiological measurements, ideally in a predictive sense, and under different input regimes in which n...

journal_title：Frontiers in computational neuroscience

authors： Hertäg L,Hass J,Golovko T,Durstewitz D

更新日期：2012-09-06 00:00:00

abstract：:Recent research in neuroscience indicates the importance of tripartite synapses and gliotransmission mediated by astrocytes in neuronal system modulation. Although the astrocyte and neuronal network functions are interrelated, they are fundamentally different in their signaling patterns and, possibly, the time scales ...

journal_title：Frontiers in computational neuroscience

authors： Lenk K,Satuvuori E,Lallouette J,Ladrón-de-Guevara A,Berry H,Hyttinen JAK

更新日期：2020-01-22 00:00:00

abstract：:The study of sensory signaling in the visual cortex has been greatly advanced by the recording of neural activity simultaneously with the performance of a specific psychophysical task. Individual nerve cells may also increase their firing leading up to the particular choice or decision made on a single psychophysical ...

journal_title：Frontiers in computational neuroscience

authors： Parker AJ

更新日期：2013-08-13 00:00:00

abstract：:Automatic segmentation of Multiple Sclerosis (MS) lesions from Magnetic Resonance Imaging (MRI) images is essential for clinical assessment and treatment planning of MS. Recent years have seen an increasing use of Convolutional Neural Networks (CNNs) for this task. Although these methods provide accurate segmentation,...

journal_title：Frontiers in computational neuroscience

authors： Ackaouy A,Courty N,Vallée E,Commowick O,Barillot C,Galassi F

更新日期：2020-03-09 00:00:00

abstract：:Neuron encodes and transmits information through generating sequences of output spikes, which is a high energy-consuming process. The spike is initiated when membrane depolarization reaches a threshold voltage. In many neurons, threshold is dynamic and depends on the rate of membrane depolarization (dV/dt) preceding a...

journal_title：Frontiers in computational neuroscience

authors： Yi GS,Wang J,Tsang KM,Wei XL,Deng B

更新日期：2015-05-27 00:00:00

abstract：:What are the functional neuroimaging measurements required for more fully characterizing the events and locations of neocortical activity? A prime assumption has been that modulation of cortical activity will inevitably be reflected in changes in energy utilization (for the most part) changes of glucose and oxygen con...

journal_title：Frontiers in computational neuroscience

authors： Robinson SE,Mandell AJ,Coppola R

更新日期：2013-01-24 00:00:00

abstract：:Song production in songbirds is controlled by a network of nuclei distributed across several brain regions, which drives respiratory and vocal motor systems to generate sound. We built a model for birdsong production, whose variables are the average activities of different neural populations within these nuclei of the...

journal_title：Frontiers in computational neuroscience

authors： Alonso RG,Trevisan MA,Amador A,Goller F,Mindlin GB

更新日期：2015-04-07 00:00:00

abstract：:The inverse problem for estimating model parameters from brain spike data is an ill-posed problem because of a huge mismatch in the system complexity between the model and the brain as well as its non-stationary dynamics, and needs a stochastic approach that finds the most likely solution among many possible solutions...

journal_title：Frontiers in computational neuroscience

authors： Hoang H,Yamashita O,Tokuda IT,Sato MA,Kawato M,Toyama K

更新日期：2015-05-21 00:00:00

abstract：:The morphology of presynaptic specializations can vary greatly ranging from classical single-release-site boutons in the central nervous system to boutons of various sizes harboring multiple vesicle release sites. Multi-release-site boutons can be found in several neural contexts, for example at the neuromuscular junc...

journal_title：Frontiers in computational neuroscience

authors： Knodel MM,Geiger R,Ge L,Bucher D,Grillo A,Wittum G,Schuster CM,Queisser G

更新日期：2014-09-09 00:00:00

abstract：:Purpose: This study is to exam self-esteem related brain morphometry on brain magnetic resonance (MR) images using multilevel-features-based classification method. Method: The multilevel region of interest (ROI) features consist of two types of features: (i) ROI features, which include gray matter volume, white matter...

journal_title：Frontiers in computational neuroscience

authors： Peng B,Lu J,Saxena A,Zhou Z,Zhang T,Wang S,Dai Y

更新日期：2017-05-22 00:00:00

abstract：:Sensitivity analysis can provide useful information when one is interested in identifying the parameter θ of a system since it measures the variations of the output u when θ changes. In the literature two different sensitivity functions are frequently used: the traditional sensitivity functions (TSF) and the generaliz...

journal_title：Frontiers in computational neuroscience

authors： Troparevsky MI,Rubio D,Saintier N

更新日期：2010-09-30 00:00:00

abstract：:A vast amount of information about the external world continuously flows into the brain, whereas its capacity to process such information is limited. Attention enables the brain to allocate its resources of information processing to selected sensory inputs for reducing its computational load, and effects of attention ...

journal_title：Frontiers in computational neuroscience

authors： Wagatsuma N,Potjans TC,Diesmann M,Fukai T

更新日期：2011-07-08 00:00:00

abstract：:A neural code based on sequences of spikes can consume a significant portion of the brain's energy budget. Thus, energy considerations would dictate that spiking activity be kept as low as possible. However, a high spike-rate improves the coding and representation of signals in spike trains, particularly in sensory sy...

journal_title：Frontiers in computational neuroscience

authors： Jones DL,Johnson EC,Ratnam R

更新日期：2015-06-02 00:00:00

abstract：:We do not claim that the brain is completely deterministic, and we agree that noise may be beneficial in some cases. But we suggest that neuronal variability may be often overestimated, due to uncontrolled internal variables, and/or the use of inappropriate reference times. These ideas are not new, but should be re-ex...

journal_title：Frontiers in computational neuroscience

authors： Masquelier T

更新日期：2013-02-25 00:00:00

abstract：:We present a high-capacity model for one-shot association learning (hetero-associative memory) in sparse networks. We assume that basic patterns are pre-learned in networks and associations between two patterns are presented only once and have to be learned immediately. The model is a combination of an Amit-Fusi like ...

journal_title：Frontiers in computational neuroscience

authors： Einarsson H,Lengler J,Steger A

更新日期：2014-11-07 00:00:00

abstract：:Statistical learning is a learning mechanism based on transition probability in sequences such as music and language. Recent computational and neurophysiological studies suggest that the statistical learning contributes to production, action, and musical creativity as well as prediction and perception. The present stu...

journal_title：Frontiers in computational neuroscience

authors： Daikoku T

更新日期：2019-10-02 00:00:00

abstract：:Molecular switches, such as the protein kinase CaMKII, play a fundamental role in cell signaling by decoding inputs into either high or low states of activity; because the high activation state can be turned on and persist after the input ceases, these switches have earned a reputation as "digital." Although this on/o...

journal_title：Frontiers in computational neuroscience

authors： Clarke SE

更新日期：2018-11-22 00:00:00

abstract：:Objective: To study the effect of directional deep brain stimulation (DBS) electrode configuration and vertical electrode spacing on the volume of tissue activated (VTA) in the globus pallidus, pars interna (GPi). Background: Directional DBS leads may allow clinicians to precisely direct current fields to different fu...

journal_title：Frontiers in computational neuroscience

authors： Zhang S,Tagliati M,Pouratian N,Cheeran B,Ross E,Pereira E

更新日期：2020-09-25 00:00:00

abstract：:We often encounter pairs of variables in the world whose mutual relationship can be described by a function. After training, human responses closely correspond to these functional relationships. Here we study how humans predict unobserved segments of a function that they have been trained on and we compare how human p...

journal_title：Frontiers in computational neuroscience

authors： Narain D,Smeets JB,Mamassian P,Brenner E,van Beers RJ

更新日期：2014-09-30 00:00:00

abstract：:Over the last decade robotics has attracted a great deal of interest from teachers and researchers as a valuable educational tool from preschool to highschool levels. The implementation of social-support behaviors in robot tutors, in particular in the emotional dimension, can make a significant contribution to learnin...

journal_title：Frontiers in computational neuroscience

authors： Imbernón Cuadrado LE,Manjarrés Riesco Á,De La Paz López F

更新日期：2016-08-03 00:00:00

abstract：:Head direction cells fire to signal the direction in which an animal's head is pointing. They are able to track head direction using only internally-derived information (path integration)In this simulation study we investigate the factors that affect path integration accuracy. Specifically, two major limiting factors ...

journal_title：Frontiers in computational neuroscience

authors： Page HJ,Walters D,Stringer SM

更新日期：2015-02-06 00:00:00

abstract：:This paper proposed a new method to determine the neuronal tuning curves for maximum information efficiency by computing the optimum firing rate distribution. Firstly, we proposed a general definition for the information efficiency, which is relevant to mutual information and neuronal energy consumption. The energy co...

journal_title：Frontiers in computational neuroscience

authors： Han F,Wang Z,Fan H

更新日期：2017-02-21 00:00:00

abstract：:Burst spike patterns are common in regions of the hippocampal formation such as the subiculum and medial entorhinal cortex (MEC). Neurons in these areas are immersed in extracellular electrical potential fluctuations often recorded as the local field potential (LFP). LFP rhythms within different frequency bands are li...

journal_title：Frontiers in computational neuroscience

authors： Constantinou M,Gonzalo Cogno S,Elijah DH,Kropff E,Gigg J,Samengo I,Montemurro MA

更新日期：2016-12-26 00:00:00

abstract：:The muscle synergy hypothesis assumes that individual muscle synergies are independent of each other and voluntarily controllable. However, this assumption has not been empirically tested. This study tested if human subjects can voluntarily activate individual muscle synergies extracted by non-negative matrix factoriz...

journal_title：Frontiers in computational neuroscience

authors： Togo S,Imamizu H

更新日期：2017-09-06 00:00:00

abstract：:A wide range of blind source separation methods have been used in motor control research for the extraction of movement primitives from EMG and kinematic data. Popular examples are principal component analysis (PCA), independent component analysis (ICA), anechoic demixing, and the time-varying synergy model (d'Avella ...

journal_title：Frontiers in computational neuroscience

authors： Endres DM,Chiovetto E,Giese MA

更新日期：2013-12-20 00:00:00

abstract：:Scientific research produces new knowledge, technologies, and clinical treatments that can lead to enormous returns. Often, the path from basic research to new paradigms and direct impact on society takes time. Precise quantification of scientific output in the short-term is not an easy task but is critical for evalua...

journal_title：Frontiers in computational neuroscience

authors： Kreiman G,Maunsell JH

更新日期：2011-11-10 00:00:00

abstract：:We present a phenomenological model of electrically stimulated auditory nerve fibers (ANFs). The model reproduces the probabilistic and temporal properties of the ANF response to both monophasic and biphasic stimuli, in isolation. The main contribution of the model lies in its ability to reproduce statistics of the AN...

journal_title：Frontiers in computational neuroscience

authors： Horne CD,Sumner CJ,Seeber BU

更新日期：2016-02-08 00:00:00

abstract：:Neuronal action potentials or spikes provide a long-range, noise-resistant means of communication between neurons. As point processes single spikes contain little information in themselves, i.e., outside the context of spikes from other neurons. Moreover, they may fail to cross a synapse. A burst, which consists of a ...

journal_title：Frontiers in computational neuroscience

authors： Zeldenrust F,Wadman WJ,Englitz B

更新日期：2018-07-06 00:00:00

abstract：:In synapses, calcium is required for modulating synaptic transmission, plasticity, synaptogenesis, and synaptic pruning. The regulation of calcium dynamics within neurons involves cellular mechanisms such as synaptically activated channels and pumps, calcium buffers, and calcium sequestrating organelles. Many experime...

journal_title：Frontiers in computational neuroscience

authors： Hu E,Mergenthal A,Bingham CS,Song D,Bouteiller JM,Berger TW

更新日期：2018-07-27 00:00:00

abstract：:The output of primary visual cortex (V1) is a piecemeal representation of the visual scene and the response of any one cell cannot unambiguously guide sensorimotor behavior. It remains unsolved how subsequent stages of cortical processing combine ("pool") these early visual signals into a coherent representation. We (...

journal_title：Frontiers in computational neuroscience

authors： Rocchi F,Ledgeway T,Webb BS

更新日期：2013-11-18 00:00:00