Diagnosis of Autism Spectrum Disorder Using Central-Moment Features From Low- and High-Order Dynamic Resting-State Functional Connectivity Networks.

abstract：:In situ hybridization (ISH) is a powerful technique that is used to detect the localization of specific nucleic acid sequences for understanding the organization, regulation, and function of genes. However, in most cases, RNA probes are obtained by in vitro transcription from plasmids containing specific promoter elem...

journal_title：Frontiers in neuroscience

authors： Hua R,Yu S,Liu M,Li H

更新日期：2018-05-02 00:00:00

abstract：:Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for neurotherapeutics of the central nervous system. In general, conventional MRI [i.e., T2w, T2∗w, gadolinium (Gd) enhanced T1w] is used to monitor the effects of pFUS+MB on BBBO...

journal_title：Frontiers in neuroscience

authors： Tu TW,Kovacs ZI,Sundby M,Witko JA,Papadakis GZ,Reid WC,Hammoud DA,Frank JA

更新日期：2020-08-25 00:00:00

abstract：:Alzheimer's disease (AD) is a neurocognitive disorder that impacts both the brain and behavior. Metal ions, including zinc (Zn), have been seen to play an important role in AD-related pathology. In this study, we show alterations in wheel-running behavior both early and late in disease progression in a novel dual Tg m...

journal_title：Frontiers in neuroscience

authors： Lippi SLP,Kakalec PA,Smith ML,Flinn JM

更新日期：2020-08-14 00:00:00

abstract：:This study was to explore the mechanisms underlying 1,2-dichloroethane (1,2-DCE) induced brain edema by focusing on alteration of matrix metalloproteinase-2 (MMP-2) in rat astrocytes induced by 2-chloroethanol (2-CE), an intermediate metabolite of 1,2-DCE in vivo. Protein and mRNA levels of MMP-2, and the phosphorylat...

journal_title：Frontiers in neuroscience

authors： Sun Q,Liao Y,Wang T,Tang H,Wang G,Zhao F,Jin Y

更新日期：2017-01-04 00:00:00

abstract：:Diffusion magnetic resonance imaging (dMRI) is a compelling tool for investigating the structure and geometry of brain tissue based on indirect measurement of the diffusion anisotropy of water. Recent developments in global top-down tractogram optimizations enable the estimation of streamline weights, which characteri...

journal_title：Frontiers in neuroscience

authors： Sommer S,Kozerke S,Seifritz E,Staempfli P

更新日期：2017-12-22 00:00:00

abstract：:Hardware-based spiking neural networks (SNNs) inspired by a biological nervous system are regarded as an innovative computing system with very low power consumption and massively parallel operation. To train SNNs with supervision, we propose an efficient on-chip training scheme approximating backpropagation algorithm ...

journal_title：Frontiers in neuroscience

authors： Kwon D,Lim S,Bae JH,Lee ST,Kim H,Seo YT,Oh S,Kim J,Yeom K,Park BG,Lee JH

更新日期：2020-07-07 00:00:00

abstract：:Although the genetic basis of Tourette Syndrome (TS) remains unclear, several candidate genes have been implicated. Using a set of 382 TS individuals of European ancestry we investigated four candidate genes for TS (HDC, SLITRK1, BTBD9, and SLC6A4) in an effort to identify possibly causal variants using a targeted re-...

journal_title：Frontiers in neuroscience

authors： Alexander J,Potamianou H,Xing J,Deng L,Karagiannidis I,Tsetsos F,Drineas P,Tarnok Z,Rizzo R,Wolanczyk T,Farkas L,Nagy P,Szymanska U,Androutsos C,Tsironi V,Koumoula A,Barta C,TSGeneSEE.,Sandor P,Barr CL,Tischfield

更新日期：2016-09-21 00:00:00

abstract：:Cognitive control of emotions depends on intermodular long-distance communications. However, negative connections between connector hubs are removed by traditional hard-thresholding approach in graph-theoretical research. Using soft-thresholding approach to reserve negative links, we explore time-varying features of c...

journal_title：Frontiers in neuroscience

authors： Zhang W,Chen J,Ren G,Tang F,Liu Q,Li H

更新日期：2019-10-25 00:00:00

abstract：:Advanced algorithms are required to reveal the complex relations between neural and behavioral data. In this study, forelimb electromyography (EMG) signals were reconstructed from multi-unit neural signals recorded with multiple electrode arrays (MEAs) from the corticospinal tract (CST) in rats. A six-layer convolutio...

journal_title：Frontiers in neuroscience

authors： Guo Y,Gok S,Sahin M

更新日期：2018-10-17 00:00:00

abstract：:The analysis of spontaneous functional connectivity (sFC) reveals the statistical connections between regions of the brain consistent with underlying functional communication networks within the brain. In this work, we describe the implementation of a complete all-to-all network analysis of resting state neuronal acti...

journal_title：Frontiers in neuroscience

authors： Schmidt BT,Ghuman AS,Huppert TJ

更新日期：2014-06-11 00:00:00

abstract：INTRODUCTION:Impairments in walking speed and capacity are common problems after stroke which may benefit from treadmill training. However, standard treadmills, are unable to adapt to the slower walking speeds of stroke survivors and are unable to automate training progression. This study tests a Variable Automated Spe...

journal_title：Frontiers in neuroscience

authors： Chua KS,Chee J,Wong CJ,Lim PH,Lim WS,Hoo CM,Ong WS,Shen ML,Yu WS

更新日期：2015-07-10 00:00:00

abstract：:Chemical communication via sex pheromones is critical for successful reproduction but the underlying neural mechanisms are not well-understood. The goldfish is a tractable model because sex pheromones have been well-characterized in this species. We used male goldfish forebrain explants in vitro and performed whole-ce...

journal_title：Frontiers in neuroscience

authors： Lado WE,Spanswick DC,Lewis JE,Trudeau VL

更新日期：2014-06-30 00:00:00

abstract：:The R47H coding variant of the triggering receptor expressed on myeloid cells-2 (TREM2) increases the risk of Alzheimer's disease (AD) similar to apolipoprotein E4. TREM2 R47H has recently been shown to have impaired binding to damage-associated lipid or apolipoprotein ligands. However, it is not known how this R47H v...

journal_title：Frontiers in neuroscience

authors： Park JS,Ji IJ,Kim DH,An HJ,Yoon SY

更新日期：2017-01-18 00:00:00

abstract：:In this work, we present a neuromorphic architecture for head pose estimation and scene representation for the humanoid iCub robot. The spiking neuronal network is fully realized in Intel's neuromorphic research chip, Loihi, and precisely integrates the issued motor commands to estimate the iCub's head pose in a neuro...

journal_title：Frontiers in neuroscience

authors： Kreiser R,Renner A,Leite VRC,Serhan B,Bartolozzi C,Glover A,Sandamirskaya Y

更新日期：2020-06-23 00:00:00

abstract：:This paper presents a unique approach for wavelet-based MRI brain image de-noising. Adaptive soft and hard threshold functions are first proposed to improve the results of standard soft and hard threshold functions for image de-noising in the wavelet domain. Then, we applied the newly emerged improved adaptive general...

journal_title：Frontiers in neuroscience

authors： Amiri Golilarz N,Gao H,Kumar R,Ali L,Fu Y,Li C

更新日期：2020-07-22 00:00:00

abstract：:The motor system has the flexibility to update motor plans according to systematic changes in the environment or the body. This capacity is studied in the laboratory through sensorimotor adaptation paradigms imposing sustained and predictable motor demands specific to the task at hand. However, these studies are tied ...

journal_title：Frontiers in neuroscience

authors： Aucie Y,Zhang X,Sargent R,Torres-Oviedo G

更新日期：2020-03-06 00:00:00

abstract：:The subventricular zone (SVZ) contains neural stem cells (NSCs) that generate new neurons throughout life. Many brain diseases stimulate NSCs proliferation, neuronal differentiation and homing of these newborns cells into damaged regions. However, complete cell replacement has never been fully achieved. Hence, the ide...

journal_title：Frontiers in neuroscience

authors： Eiriz MF,Valero J,Malva JO,Bernardino L

更新日期：2014-06-16 00:00:00

abstract：:High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. However, test-retest reliability measurements are essential to asc...

journal_title：Frontiers in neuroscience

authors： Boukadi M,Marcotte K,Bedetti C,Houde JC,Desautels A,Deslauriers-Gauthier S,Chapleau M,Boré A,Descoteaux M,Brambati SM

更新日期：2019-01-14 00:00:00

abstract：:Environmental sounds form part of our daily life. With the advancement of deep learning models and the abundance of training data, the performance of automatic sound classification (ASC) systems has improved significantly in recent years. However, the high computational cost, hence high power consumption, remains a ma...

journal_title：Frontiers in neuroscience

authors： Wu J,Chua Y,Zhang M,Li H,Tan KC

更新日期：2018-11-19 00:00:00

abstract：:Motor performance varies substantially between individuals. This variance is rooted in individuals' innate motor abilities, and should thus have a neural signature underlying these differences in behavior. Could these individual differences be detectable with neural measurements acquired at rest? Here, we tested the h...

journal_title：Frontiers in neuroscience

authors： Herszage J,Dayan E,Sharon H,Censor N

更新日期：2020-02-05 00:00:00

abstract：Background:Endovascular treatment of large or giant non-saccular vertebrobasilar aneurysms (VBAs) by conventional stents is difficult and has unsatisfactory outcomes. Object:This study was performed to retrospectively analyze the safety and efficacy of a flow diverter in treating large and giant non-saccular VBAs. Me...

journal_title：Frontiers in neuroscience

authors： Wang J,Jia L,Duan Z,Wang Z,Yang X,Zhang Y,Lv M

更新日期：2019-11-28 00:00:00

abstract：:Astrocytes are the most abundant type of glial cell in the central nervous system and perform a myriad of vital functions, however, the nature of their diversity remains a longstanding question in neuroscience. Using transcription factor motif discovery analysis on region-specific gene signatures from astrocytes we un...

journal_title：Frontiers in neuroscience

authors： Lozzi B,Huang TW,Sardar D,Huang AY,Deneen B

更新日期：2020-02-21 00:00:00

abstract：:The fragile X mental retardation protein (FMRP) is an RNA-binding protein that regulates mRNA metabolism. FMRP has been largely studied in the brain, where the absence of this protein leads to fragile X syndrome, the most frequent form of inherited intellectual disability. Since the identification of the FMRP gene in ...

journal_title：Frontiers in neuroscience

authors： Fernández E,Rajan N,Bagni C

更新日期：2013-10-24 00:00:00

abstract：:Neurodegenerative diseases are among the leading causes of disability and death worldwide. The disease-related socioeconomic burden is expected to increase with the steadily increasing life expectancy. In spite of decades of clinical and basic research, most strategies designed to manage degenerative brain diseases ar...

journal_title：Frontiers in neuroscience

authors： Castillo X,Castro-Obregón S,Gutiérrez-Becker B,Gutiérrez-Ospina G,Karalis N,Khalil AA,Lopez-Noguerola JS,Rodríguez LL,Martínez-Martínez E,Perez-Cruz C,Pérez-Velázquez J,Piña AL,Rubio K,García HPS,Syeda T,Vanoye-Carlo A,Vi

更新日期：2019-07-24 00:00:00

abstract：:Glutamate-induced excitotoxicity is one of the main causes of neuronal cell death in stroke. Compound 22a has been previously reported as a promising neuroprotective compound derived from tetramethylpyrazine, which is a widely used active ingredient of traditional Chinese medicine Chuanxiong (Ligusticum wallichii Fran...

journal_title：Frontiers in neuroscience

authors： Chen H,Cao J,Zhu Z,Zhang G,Shan L,Yu P,Wang Y,Sun Y,Zhang Z

更新日期：2018-08-15 00:00:00

abstract：:Although the major causative factors of Alzheimer's disease (AD) are the accumulation of amyloid β and hyperphosphorylated tau, AD can also be caused by metabolic dysfunction. The major clinical symptom of AD is cognitive dysfunction. However, AD is also accompanied by various secondary symptoms such as depression, sl...

journal_title：Frontiers in neuroscience

authors： Kim S,Nam Y,Shin SJ,Park YH,Jeon SG,Kim JI,Kim MJ,Moon M

更新日期：2020-09-24 00:00:00

abstract：:The structure of gene coexpression networks reflects the activation and interaction of multiple cellular systems. Since the pathology of neuropsychiatric disorders is influenced by diverse cellular systems and pathways, we investigated gene coexpression networks in major depression, and searched for putative unifying ...

journal_title：Frontiers in neuroscience

authors： Gaiteri C,Sibille E

更新日期：2011-08-30 00:00:00

abstract：:Several studies of semantic memory in non-musical domains involving recognition of items from long-term memory have shown an age-related shift from the medial temporal lobe structures to the frontal lobe. However, the effects of aging on musical semantic memory remain unexamined. We compared activation associated with...

journal_title：Frontiers in neuroscience

authors： Sikka R,Cuddy LL,Johnsrude IS,Vanstone AD

更新日期：2015-10-06 00:00:00

abstract：:Recent neuroimaging studies in primates aim to define the functional properties of auditory cortical areas, especially areas beyond A1, in order to further our understanding of the auditory cortical organization. Precise mapping of functional magnetic resonance imaging (fMRI) results and interpretation of their locali...

journal_title：Frontiers in neuroscience

authors： Joly O,Baumann S,Balezeau F,Thiele A,Griffiths TD

更新日期：2014-07-21 00:00:00

abstract：:People generally prefer risky options, which have fully specified outcome probabilities, to ambiguous options, which have unspecified probabilities. This preference, formalized in economics, is strong enough that people will reliably prefer a risky option to an ambiguous option with a greater expected value. Explanati...

journal_title：Frontiers in neuroscience

authors： Hayden BY,Heilbronner SR,Platt ML

更新日期：2010-09-17 00:00:00