The Potential Roles of Ghrelin in Metabolic Syndrome and Secondary Symptoms of Alzheimer's Disease.

abstract：:Opioid abuse is now the primary cause of accidental deaths in the United States. Studies over several decades established the cyclical nature of abused drugs of choice, with a current resurgence of heroin abuse and, more recently, fentanyl's emergence as a major precipitant of drug-related deaths. To better understand...

journal_title：Frontiers in neuroscience

authors： Saad MH,Savonen CL,Rumschlag M,Todi SV,Schmidt CJ,Bannon MJ

更新日期：2018-10-23 00:00:00

abstract：:Psychiatric disorders represent a great medical and social challenge and people suffering from these conditions face many impairments regarding personal and professional life. In addition, a mental disorder will manifest itself in approximately one quarter of the world's population at some period of their life. Dysfun...

journal_title：Frontiers in neuroscience

authors： Zuccoli GS,Saia-Cereda VM,Nascimento JM,Martins-de-Souza D

更新日期：2017-09-07 00:00:00

abstract：:The neuronal cascade related to the perception of either purely olfactory or trigeminal airborne chemicals has been investigated using electroencephalography (EEG) microstate analyses and source localization. However, most airborne chemicals are bimodal in nature, encompassing both properties. Moreover, there is an on...

journal_title：Frontiers in neuroscience

authors： Hucke CI,Heinen RM,Pacharra M,Wascher E,van Thriel C

更新日期：2021-01-13 00:00:00

abstract：:Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity. However, in a number of neurodegenerative diseases, including Alzheimer's disease (AD), tau undergoes pathological modifications i...

journal_title：Frontiers in neuroscience

authors： Pérez MJ,Jara C,Quintanilla RA

更新日期：2018-07-05 00:00:00

abstract：:Alzheimer's disease (AD) is a neurocognitive disorder that impacts both the brain and behavior. Metal ions, including zinc (Zn), have been seen to play an important role in AD-related pathology. In this study, we show alterations in wheel-running behavior both early and late in disease progression in a novel dual Tg m...

journal_title：Frontiers in neuroscience

authors： Lippi SLP,Kakalec PA,Smith ML,Flinn JM

更新日期：2020-08-14 00:00:00

abstract：:The classification of electroencephalogram (EEG) signals is of significant importance in brain-computer interface (BCI) systems. Aiming to achieve intelligent classification of EEG types with high accuracy, a classification methodology using sparse representation (SR) and fast compression residual convolutional neural...

journal_title：Frontiers in neuroscience

authors： Huang JS,Li Y,Chen BQ,Lin C,Yao B

更新日期：2020-09-30 00:00:00

abstract：:The decoding of selective auditory attention from noninvasive electroencephalogram (EEG) data is of interest in brain computer interface and auditory perception research. The current state-of-the-art approaches for decoding the attentional selection of listeners are based on linear mappings between features of sound s...

journal_title：Frontiers in neuroscience

authors： Wong DDE,Fuglsang SA,Hjortkjær J,Ceolini E,Slaney M,de Cheveigné A

更新日期：2018-08-07 00:00:00

abstract：:Background: Significant progress toward the recovery of useful vision in blind patients with severe degenerative retinal diseases caused by photoreceptor death has been achieved with the development of visual prostheses that stimulate the retina electrically. However, currently used prostheses do not provide feedback ...

journal_title：Frontiers in neuroscience

authors： Rincón Montes V,Gehlen J,Lück S,Mokwa W,Müller F,Walter P,Offenhäusser A

更新日期：2019-04-30 00:00:00

abstract：:Luqin is a neuropeptide that was discovered and named on account of its expression in left upper quadrant cells of the abdominal ganglion in the mollusc Aplysia californica. Subsequently, luqin-type peptides were identified as cardio-excitatory neuropeptides in other molluscs and a cognate receptor was discovered in t...

journal_title：Frontiers in neuroscience

authors： Yañez-Guerra LA,Elphick MR

更新日期：2020-02-18 00:00:00

abstract：:Alzheimer's disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal area. In the present study, cholinergic cell death was induced by in...

journal_title：Frontiers in neuroscience

authors： Dobryakova YV,Volobueva MN,Manolova AO,Medvedeva TM,Kvichansky AA,Gulyaeva NV,Markevich VA,Stepanichev MY,Bolshakov AP

更新日期：2019-03-12 00:00:00

abstract：:While adult neurogenesis is considered to be restricted to the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ), recent studies in humans and rodents provide evidence for newly generated neurons in regions generally considered as non-neurogenic, e.g., the striatum. Stimulating dopaminergic neurotransmi...

journal_title：Frontiers in neuroscience

authors： Salvi R,Steigleder T,Schlachetzki JC,Waldmann E,Schwab S,Winner B,Winkler J,Kohl Z

更新日期：2016-03-11 00:00:00

abstract：:Spasticity is a common comorbidity associated with spinal cord injury (SCI). Robotic exoskeletons have recently emerged to facilitate legged mobility in people with motor complete SCI. Involuntary muscle activity attributed to spasticity, however, can prevent such individuals from using an exoskeleton. Specifically, a...

journal_title：Frontiers in neuroscience

authors： Ekelem A,Goldfarb M

更新日期：2018-06-01 00:00:00

abstract：:Reconsolidation of memories has mostly been studied at the behavioral and molecular level. Here, we put forward a simple extension of existing computational models of synaptic consolidation to capture hippocampal slice experiments that have been interpreted as reconsolidation at the synaptic level. The model implement...

journal_title：Frontiers in neuroscience

authors： Kastner DB,Schwalger T,Ziegler L,Gerstner W

更新日期：2016-05-18 00:00:00

abstract：:Over the past several decades, clinical studies have shown significant analgesic effects of acupuncture. The efficacy of acupuncture treatment has improved with the recent development of nanoporous needles (PN), which are produced by modifying the needle surface using nanotechnology. Herein, we showed that PN at acupo...

journal_title：Frontiers in neuroscience

authors： Bae SJ,Lim J,Lee S,Choi H,Jang JH,Kim YK,Oh JY,Park JH,Jung HS,Chae Y,In SI,Park HJ

更新日期：2019-06-20 00:00:00

abstract：:The neural generators of the frequency-following response (FFR), a neural response widely used to study the human auditory system, remain unclear. There is evidence that the balance between cortical and subcortical contributions to the FFR varies with stimulus frequency. In this study, we tried to clarify whether this...

journal_title：Frontiers in neuroscience

authors： Zhang X,Gong Q

更新日期：2019-02-26 00:00:00

abstract：:Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are reaching physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. T...

journal_title：Frontiers in neuroscience

authors： Hasler J,Marr B

更新日期：2013-09-10 00:00:00

abstract：:The aim of this work was to test if a novel transcranial direct current stimulation (tDCS) montage boosts the accuracy of lower limb motor imagery (MI) detection by using a real-time brain-machine interface (BMI) based on electroencephalographic (EEG) signals. The tDCS montage designed was composed of two anodes and o...

journal_title：Frontiers in neuroscience

authors： Rodríguez-Ugarte M,Iáñez E,Ortiz M,Azorín JM

更新日期：2018-10-23 00:00:00

abstract：Objective:Magnetic resonance-guided focused ultrasound surgery (MRgFUS) lesioning is a new treatment for brain disorders. However, the skull is a major barrier of ultrasound sonication in MRgFUS because it has an irregular surface and varies its size and shape among individuals. We recently developed the concept of sku...

journal_title：Frontiers in neuroscience

authors： Chang KW,Rachmilevitch I,Chang WS,Jung HH,Zadicario E,Prus O,Chang JW

更新日期：2021-01-12 00:00:00

abstract：:Progranulin (PGRN) is a tightly regulated, secreted glycoprotein involved in a wide range of biological processes that is of tremendous interest to the scientific community due to its involvement in neoplastic, neurodevelopmental, and neurodegenerative diseases. In particular, progranulin haploinsufficiency leads to f...

journal_title：Frontiers in neuroscience

authors： Gururaj S,Sampognaro PJ,Argouarch AR,Kao AW

更新日期：2020-12-14 00:00:00

abstract：:The menstrual cycle has attracted research interest ever since the 1930s. For many researchers the menstrual cycle is an excellent model of ovarian steroid influence on emotion, behavior, and cognition. Over the past years methodological improvements in menstrual cycle studies have been noted, and this review summariz...

journal_title：Frontiers in neuroscience

authors： Sundström Poromaa I,Gingnell M

更新日期：2014-11-24 00:00:00

abstract：:The visual system is organized in a parallel and hierarchical architecture. However, the plasticity in hierarchical neural networks is controversial across different response features and at different levels. In this study, we recorded areas 17 and 21a, earlier and intermediate stages of the visual cortex in the cat, ...

journal_title：Frontiers in neuroscience

authors： Wang J,Ni Z,Jin A,Yu T,Yu H

更新日期：2019-10-11 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) allows studying human brain function non-invasively up to the spatial resolution of cortical columns and layers. Most fMRI acquisitions rely on the blood oxygenation level dependent (BOLD) contrast employing T(*) 2 weighted 2D multi-slice echo-planar imaging (EPI). At ultra...

journal_title：Frontiers in neuroscience

authors： Kemper VG,De Martino F,Vu AT,Poser BA,Feinberg DA,Goebel R,Yacoub E

更新日期：2015-05-05 00:00:00

abstract：:Emerging neuroimaging studies emphasize the dynamic organization of spontaneous brain activity in both human and non-human primates, even under anesthesia. In a recent study, we were able to characterize the heterogeneous architecture of intrinsic functional flexibility in the awake, resting human brain using time-res...

journal_title：Frontiers in neuroscience

authors： Yin D,Zhang Z,Wang Z,Zeljic K,Lv Q,Cai D,Wang Y,Wang Z

更新日期：2019-02-28 00:00:00

abstract：:The neurodegenerative disorder multiple system atrophy (MSA) is characterized by autonomic failure, cerebellar ataxia and parkinsonism in any combination associated with predominantly oligodendroglial α-synuclein (α-syn) aggregates (glial cytoplasmic inclusions = GCIs). To date, there is no effective disease modifying...

journal_title：Frontiers in neuroscience

authors： Fellner L,Kuzdas-Wood D,Levin J,Ryazanov S,Leonov A,Griesinger C,Giese A,Wenning GK,Stefanova N

更新日期：2016-03-10 00:00:00

abstract：:α-Synuclein is a 140-amino acid protein that readily misfolds and is associated with the Lewy body pathology found in sporadic and genetic forms of Parkinson's disease. We and others have shown that wild-type α-synuclein is a damage-associated molecular pattern that directly elicits a proinflammatory response in micro...

journal_title：Frontiers in neuroscience

authors： Sánchez K,Maguire-Zeiss K

更新日期：2020-12-02 00:00:00

abstract：:Although, cochlear implants (CI) traditionally have been used to treat individuals with bilateral profound sensorineural hearing loss, a recent trend is to implant individuals with residual low-frequency hearing. Notably, many of these individuals demonstrate an air-bone gap (ABG) in low-frequency, pure-tone threshold...

journal_title：Frontiers in neuroscience

authors： Koka K,Saoji AA,Attias J,Litvak LM

更新日期：2017-04-18 00:00:00

abstract：:For brain-computer interfaces (BCIs) that utilize visual cues to direct the user, the neural signals extracted by the computer are representative of ongoing processes, visual evoked responses, and voluntary modulation. We proposed to use three brain signatures for predicting success on a single trial of a BCI task. Th...

journal_title：Frontiers in neuroscience

authors： Geronimo A,Kamrunnahar M,Schiff SJ

更新日期：2016-04-26 00:00:00

abstract：:Magnetic field inhomogeneities cause geometric distortions of echo planar images used for functional magnetic resonance imaging (fMRI). To reduce this problem, distortion correction (DC) with field map is widely used for both task and resting-state fMRI (rs-fMRI). Although DC with field map has been reported to improv...

journal_title：Frontiers in neuroscience

authors： Togo H,Rokicki J,Yoshinaga K,Hisatsune T,Matsuda H,Haga N,Hanakawa T

更新日期：2017-12-01 00:00:00

abstract：:Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is believed to play a role in listening in noise and protection from a...

journal_title：Frontiers in neuroscience

authors： Smith SB,Lichtenhan JT,Cone BK

更新日期：2017-04-04 00:00:00

abstract：:Silver nano-particles (Ag-NPs) are becoming increasingly prevalent in consumer products as antibacterial agents. The increased use of Ag NP-enhanced products will almost certainly increase environmental silver levels, resulting in increased exposures and the potential for increased adverse reactions including neurotox...

journal_title：Frontiers in neuroscience

authors： Liu F,Mahmood M,Xu Y,Watanabe F,Biris AS,Hansen DK,Inselman A,Casciano D,Patterson TA,Paule MG,Slikker W Jr,Wang C

更新日期：2015-04-08 00:00:00