2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways.

abstract：:Changing gait is crucial for adaptive and smooth animal locomotion. Although it remains unclear what makes animals decide on a specific gait, energy efficiency is an important factor. It has been reported that the relationship of oxygen consumption with speed is U-shaped for each horse gait and that different gaits ha...

journal_title：Frontiers in neuroscience

authors： Toeda M,Aoi S,Fujiki S,Funato T,Tsuchiya K,Yanagihara D

更新日期：2020-01-17 00:00:00

abstract：:Advanced societies face increased health problems related to various stresses. Chronic psychological stress is a major risk factor for psychiatric disorders such as depression. Although therapeutic agents reduce several symptoms of depression, most have side effects in a broad range of the population. Furthermore, som...

journal_title：Frontiers in neuroscience

authors： Goto T,Tomonaga S,Okayama T,Toyoda A

更新日期：2016-03-01 00:00:00

abstract：:The formation of the six-layered structure of the mammalian cortex via the inside-out pattern of neuronal migration is fundamental to neocortical functions. Extracellular cues such as Reelin induce intracellular signaling cascades through the protein phosphorylation. Migrating neurons also have intrinsic machineries t...

journal_title：Frontiers in neuroscience

authors： Ohshima T

更新日期：2015-01-13 00:00:00

abstract：:A vital feature in the success of Ecdysozoa is their ability to shed their exoskeleton (a process called ecdysis) such that they can grow or change their morphology. In holometabolous insects, these behaviors are orchestrated by the sequential actions of neuropeptides, one of which is crustacean cardioactive peptide (...

journal_title：Frontiers in neuroscience

authors： Lee D,Orchard I,Lange AB

更新日期：2013-11-05 00:00:00

abstract：:Antibiotic-mediated changes to the intestinal microbiome have largely been assumed to be the basis of antibiotic-induced neurophysiological and behavioral changes. However, relatively little research has addressed whether antibiotics act directly on the host nervous system to produce these changes. We aimed to identif...

journal_title：Frontiers in neuroscience

authors： Delungahawatta T,Amin JY,Stanisz AM,Bienenstock J,Forsythe P,Kunze WA

更新日期：2017-10-20 00:00:00

abstract：:Traumatic brain injury (TBI) is a kind of severe brain injury characterized with a high incidence rate and a high disability rate. Low-intensity transcranial ultrasound stimulation (LITUS) is a promising neuroprotective method for improving the functional prognosis of TBI. The fractional anisotropy (FA) value and mean...

journal_title：Frontiers in neuroscience

authors： Zheng T,Du J,Yuan Y,Wu S,Jin Y,Wang Z,Liu D,Shi Q,Wang X,Liu L

更新日期：2020-03-10 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by T helper (h)1 and/or Th17 CD4 T cells that drive inflammatory lesion development along with demyelination and neuronal damage. Defects in immune regulatory mechanisms are thought to play a role in the pathogenesis of MS. W...

journal_title：Frontiers in neuroscience

authors： Miller NM,Wang J,Tan Y,Dittel BN

更新日期：2015-08-18 00:00:00

abstract：:The dentate gyrus (DG) is a region in the mammalian brain critical for memory encoding with a neuronal architecture and function that deviates considerably from other cortical areas. One of the major differences of the DG compared to other brain regions is the finding that the dentate gyrus generates new principal neu...

journal_title：Frontiers in neuroscience

authors： Piatti VC,Ewell LA,Leutgeb JK

更新日期：2013-04-04 00:00:00

abstract：:Extrapancreatic nerves project to pancreatic islets directly or converge onto intrapancreatic ganglia. Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network. Both intrapancreatic ganglia and extrapancreatic nerves have ...

journal_title：Frontiers in neuroscience

authors： Li W,Yu G,Liu Y,Sha L

更新日期：2019-02-20 00:00:00

abstract：:Exposure in vivo (EXP) is a cognitive-behavioral treatment aimed at reducing pain-related fear in chronic pain, and has proven successful in reducing pain-related disability in patients with chronic low back pain (cLBP). The current longitudinal study aimed to reveal the neural correlates of changes in pain-related fe...

journal_title：Frontiers in neuroscience

authors： Timmers I,de Jong JR,Goossens M,Verbunt JA,Smeets RJ,Kaas AL

更新日期：2019-09-17 00:00:00

abstract：:In many species of group living invertebrates, in particular arthropods, collective decisions can emerge from the combined actions of individuals and the direct or indirect interactions between individuals. These decisions allow groups of individuals to respond quickly and accurately to changes that occur in their env...

journal_title：Frontiers in neuroscience

authors： Jeanson R,Dussutour A,Fourcassié V

更新日期：2012-08-20 00:00:00

abstract：:Hearing loss can develop as a consequence of primary auditory neuron degeneration. These neurons are present within the spiral ganglion of the inner ear and co-exist with glial cells that assist in neuronal maintenance and function. There are limited interventions for individuals with hearing impairment, hence novel b...

journal_title：Frontiers in neuroscience

authors： Meas SJ,Nishimura K,Scheibinger M,Dabdoub A

更新日期：2018-11-13 00:00:00

abstract：:The recently renewed focus on the human exploration of outer space has boosted the interest toward a variety of questions regarding health of astronauts and cosmonauts. Among the others, sleep has traditionally been considered a central issue. To extend the research chances, human sleep alterations have been investiga...

journal_title：Frontiers in neuroscience

authors： Zivi P,De Gennaro L,Ferlazzo F

更新日期：2020-08-11 00:00:00

abstract：:Environmental sounds form part of our daily life. With the advancement of deep learning models and the abundance of training data, the performance of automatic sound classification (ASC) systems has improved significantly in recent years. However, the high computational cost, hence high power consumption, remains a ma...

journal_title：Frontiers in neuroscience

authors： Wu J,Chua Y,Zhang M,Li H,Tan KC

更新日期：2018-11-19 00:00:00

abstract：:The cardiovascular and respiratory effects of exercise have been widely studied, as have the autonomic effects of imagined and observed exercise. However, the effects of observed exercise in the first person have not been documented, nor have direct recordings of muscle sympathetic nerve activity (MSNA) been obtained ...

journal_title：Frontiers in neuroscience

authors： Brown R,Kemp U,Macefield V

更新日期：2013-06-11 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, meaning a subgroup of tinnitus patients responsive to specific treatments. Tinnitus patients wi...

journal_title：Frontiers in neuroscience

authors： Edvall NK,Gunan E,Genitsaridi E,Lazar A,Mehraei G,Billing M,Tullberg M,Bulla J,Whitton J,Canlon B,Hall DA,Cederroth CR

更新日期：2019-08-22 00:00:00

abstract：:Possible risks stemming from the employment of novel, micrometer-thin printed electrodes for direct current neural stimulation are discussed. To assess those risks, electrochemical methods are used, including cyclic voltammetry, square-wave voltammetry, and electrochemical impedance spectroscopy. Experiments were cond...

journal_title：Frontiers in neuroscience

authors： Pepłowski A,Rathi S,Piotrkowski B,Ziółkowski R,Janczak D,Krzemiński J,Brosch M,Jakubowska M

更新日期：2020-10-29 00:00:00

abstract：:Chronic glial activation is characterized by an increased number of activated microglia and astroglia; these secrete free radicals and cytotoxic cytokines, subsequently causing neuronal damage. This study investigated the hypothesis that a soy-lecithin based phytosomal curcumin formulation can decrease glial activatio...

journal_title：Frontiers in neuroscience

authors： Ullah F,Liang H,Niedermayer G,Münch G,Gyengesi E

更新日期：2020-03-12 00:00:00

abstract：:The neuropeptide oxytocin (OT) plays an important role in the regulation of social and anxiety-like behavior. Our previous studies have shown that OT neurons send projections from the hypothalamus to the dorsolateral bed nucleus of the stria terminalis (BNSTdl), a forebrain region critically involved in the modulation...

journal_title：Frontiers in neuroscience

authors： Martinon D,Dabrowska J

更新日期：2018-03-21 00:00:00

abstract：:A large body of experimental and clinical evidence has strongly suggested that monoamines play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and comorbid psychiatric disorders commonly seen in people with epilepsy (PWE). However, neither the relative significance of individual m...

journal_title：Frontiers in neuroscience

authors： Svob Strac D,Pivac N,Smolders IJ,Fogel WA,De Deurwaerdere P,Di Giovanni G

更新日期：2016-11-10 00:00:00

abstract：:The structural organization of cortical areas is not random, with topographic maps commonplace in sensory processing centers. This topographical organization allows optimal wiring between neurons, multimodal sensory integration, and performs input dimensionality reduction. In this work, a model of topographic map form...

journal_title：Frontiers in neuroscience

authors： Bogdan PA,Rowley AGD,Rhodes O,Furber SB

更新日期：2018-07-02 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00

abstract：:The neuronal cascade related to the perception of either purely olfactory or trigeminal airborne chemicals has been investigated using electroencephalography (EEG) microstate analyses and source localization. However, most airborne chemicals are bimodal in nature, encompassing both properties. Moreover, there is an on...

journal_title：Frontiers in neuroscience

authors： Hucke CI,Heinen RM,Pacharra M,Wascher E,van Thriel C

更新日期：2021-01-13 00:00:00

abstract：:L-DOPA-induced dyskinesia (LID) represents one of the major problems of the long-term therapy of patients with Parkinson's disease (PD). Although, the pathophysiologic mechanisms underlying LID are not completely understood, activation of the extracellular signal regulated kinase (ERK) is recognized to play a key role...

journal_title：Frontiers in neuroscience

authors： Chen G,Nie S,Han C,Ma K,Xu Y,Zhang Z,Papa SM,Cao X

更新日期：2017-03-09 00:00:00

abstract：:Studies of delay discounting typically have involved choices between smaller, immediate outcomes and larger, delayed outcomes. In a study of delay discounting in humans, Green et al. (2005) added a period of time prior to both outcomes, creating a delay common to both. They found that the subjective value of the more ...

journal_title：Frontiers in neuroscience

authors： Calvert AL,Green L,Myerson J

更新日期：2011-08-17 00:00:00

abstract：:The goal of our research was to develop a compound computational model that predicts the "opposite" effects of the alternating aftereffects stimuli, such as the "color dove illusion" (Barkan and Spitzer, 2017), and the "filling in the afterimage after the image" (van Lier et al., 2009). The model is based on a filling...

journal_title：Frontiers in neuroscience

authors： Cohen-Duwek H,Spitzer H

更新日期：2018-08-17 00:00:00

abstract：:In the present review, we deliver an overview of the involvement of metabotropic glutamate receptor 5 (mGluR5) activity and density in pathological anxiety, mood disorders and addiction. Specifically, we will describe mGluR5 studies in humans that employed Positron Emission Tomography (PET) and combined the findings w...

journal_title：Frontiers in neuroscience

authors： Terbeck S,Akkus F,Chesterman LP,Hasler G

更新日期：2015-03-18 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive mental illness characterized by memory loss and multiple cognitive impairments. In the last several decades, significant progress has been made in understanding basic biology, molecular mechanisms, and development of biomarkers and therapeutic drugs. Multiple cellular changes ...

journal_title：Frontiers in neuroscience

authors： Amakiri N,Kubosumi A,Tran J,Reddy PH

更新日期：2019-05-03 00:00:00

abstract：:Abnormal accumulation of TAR DNA-binding protein 43 (TDP-43) in the cytoplasm and its disappearance from the nucleus are pathological features of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) and are directly involved in the pathogenesis of these conditions. TDP-43 is an essential nuclear protein...

journal_title：Frontiers in neuroscience

authors： Sugai A,Kato T,Koyama A,Koike Y,Kasahara S,Konno T,Ishihara T,Onodera O

更新日期：2018-02-01 00:00:00