Analysis of the Deleterious Single-Nucleotide Polymorphisms Associated With Antidepressant Efficacy in Major Depressive Disorder.

abstract：Background:Discharge from acute mental health services has long been associated with mortality, risk, and related adverse outcomes for patients. Many of the interventions that currently aim to reduce adverse outcomes focus on a single group of healthcare professionals within a single healthcare setting. A recent system...

journal_title：Frontiers in psychiatry

authors： Tyler N,Wright N,Grundy A,Gregoriou K,Campbell S,Waring J

更新日期：2020-04-21 00:00:00

abstract：Background:The amygdala has been proposed to be involved in the pathophysiology of pediatric and adult bipolar disorder (BD). The goal of this structural magnetic resonance imaging (sMRI) study was to investigate the morphometric characteristics of amygdala subnuclei in patients with pediatric bipolar disorder (PBD) co...

journal_title：Frontiers in psychiatry

authors： Cui D,Guo Y,Cao W,Gao W,Qiu J,Su L,Jiao Q,Lu G

更新日期：2020-06-26 00:00:00

abstract：Background:Cardiovascular disease (CVD) is a major cause of premature death in patients with psychotic disorders, where dyslipidemia occurs frequently. In the pathogenesis of these serious mental disorders, a low-grade inflammation seems to be a possible contributor. Concurrently, systemic inflammation and its interpla...

journal_title：Frontiers in psychiatry

authors： Reponen EJ,Dieset I,Tesli M,Mørch RH,Aas M,Vedal TSJ,Haug E,Drange OK,Steen NE,Hope S,Szabo A,Gohar SM,Wedervang-Resell K,Djurovic S,Melle I,Aukrust P,Andreassen OA,Ueland T

更新日期：2020-07-10 00:00:00

abstract：:Objective: Poor mental health is associated with impaired social functioning, lower quality of life, and increased risk of suicide and mortality. This study examined the prevalence of poor general mental health among older adults (aged 65 years and above) and its sociodemographic correlates in Hebei province, which is...

journal_title：Frontiers in psychiatry

authors： Jin Y,Zhang YS,Zhang Q,Rao WW,Zhang LL,Cui LJ,Li JF,Li L,Ungvari GS,Jackson T,Li KQ,Xiang YT

更新日期：2020-11-05 00:00:00

abstract：Background:High prevalence of mental disorders has been found among female prisoners in Western countries, however, little is known about the epidemiology of mental disorders in such populations in China. This study aims to investigate psychiatric morbidity and comorbidity among sentenced prisoners in a female prison i...

journal_title：Frontiers in psychiatry

authors： Zhong S,Zhu X,Chen Y,Guo H,Luo C,Liang X,Wang F,Chen H,Zhou J,Wang X

更新日期：2020-04-14 00:00:00

abstract：Background:Disorganization of semantic memory in patients with schizophrenia has been studied by referring to their category fluency performance. Recently, data-mining techniques such as singular value decomposition (SVD) analysis have been reported to be effective in elucidating the latent semantic memory structure in...

journal_title：Frontiers in psychiatry

authors： Sumiyoshi C,Fujino H,Sumiyoshi T,Yasuda Y,Yamamori H,Fujimoto M,Hashimoto R

更新日期：2018-03-21 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：INTRODUCTION:Ruminative (abstract verbal) processing during recall of aversive autobiographical memories may serve to dampen their short-term affective impact. Experimental studies indeed demonstrate that verbal processing of non-autobiographical material and positive autobiographical memories evokes weaker affective r...

journal_title：Frontiers in psychiatry

authors： Slofstra C,Eisma MC,Holmes EA,Bockting CLH,Nauta MH

更新日期：2017-05-30 00:00:00

abstract：:Prolonged bedtime smartphone use is often associated with poor sleep quality and daytime dysfunction. In addition, the unstructured nature of smartphones may lead to excessive and uncontrolled use, which can be a cardinal feature of problematic smartphone use. This study was designed to investigate functional connecti...

journal_title：Frontiers in psychiatry

authors： Paik SH,Park CH,Kim JY,Chun JW,Choi JS,Kim DJ

更新日期：2019-07-23 00:00:00

abstract：:Background: Bipolar disorder (BD) has been associated with distributed network disruption, but little is known on how different clinical subtypes, particularly those with an earlier and later onset of disease, are related to connectivity changes in white matter (WM) tracts. Methods: Diffusion tensor imaging (DTI) and ...

journal_title：Frontiers in psychiatry

authors： Alves GS,Knöchel C,Paulitsch MA,Reinke B,Carvalho AF,Feddern R,Prvulovic D,Sudo FK,Pantel J,Reif A,Oertel V

更新日期：2018-10-09 00:00:00

abstract：BACKGROUND:Traumatic brain injury (TBI) is a common cause of physical, psychological, and cognitive impairment, but many current treatments for TBI are ineffective or produce adverse side effects. Non-invasive methods of brain stimulation could help ameliorate some common trauma-induced symptoms. OBJECTIVE:This review...

journal_title：Frontiers in psychiatry

authors： Dhaliwal SK,Meek BP,Modirrousta MM

更新日期：2015-08-26 00:00:00

abstract：:Pranayama refers to a set of yoga breathing exercises. Recent evidence suggests that the practice of pranayama has positive effects on measures of clinical stress and anxiety. This study explored the impact of a Bhastrika pranayama training program on emotion processing, anxiety, and affect. We used a randomized contr...

journal_title：Frontiers in psychiatry

authors： Novaes MM,Palhano-Fontes F,Onias H,Andrade KC,Lobão-Soares B,Arruda-Sanchez T,Kozasa EH,Santaella DF,de Araujo DB

更新日期：2020-05-21 00:00:00

abstract：:What is the role and value of pleasure in addiction? Foddy and Savulescu (1) have claimed that substance use is just pleasure-oriented behavior. They describe addiction as "strong appetites toward pleasure" and argue that addicts suffer in significant part because of strong social and moral disapproval of lives domina...

journal_title：Frontiers in psychiatry

authors： Kennett J,Matthews S,Snoek A

更新日期：2013-09-25 00:00:00

abstract：Objective:There is increasing interest in the utility of gamma-band activity for assessing various brain functions, including perception, language, memory, and cognition. The auditory steady-state response (ASSR) involves neural activity in the brain elicited by trains of a click sound, and its maximum response is obta...

journal_title：Frontiers in psychiatry

authors： Hirano Y,Nakamura I,Tamura S,Onitsuka T

更新日期：2020-09-02 00:00:00

abstract：:Background: Psychiatric comorbidity is common in gambling disorder, a condition with low rates of treatment seeking. There is a paucity of documented nationwide data on gambling disorder and its co-occurring psychiatric comorbidities in the health care system. Methods: This is a nationwide register-based study of all ...

journal_title：Frontiers in psychiatry

authors： Håkansson A,Karlsson A,Widinghoff C

更新日期：2018-09-07 00:00:00

abstract：:In its initial formulation, the concept of basic symptoms (BSs) integrated findings on the early symptomatic course of schizophrenia and first in vivo evidence of accompanying brain aberrations. It argued that the subtle subclinical disturbances in mental processes described as BSs were the most direct self-experience...

journal_title：Frontiers in psychiatry

authors： Schultze-Lutter F,Debbané M,Theodoridou A,Wood SJ,Raballo A,Michel C,Schmidt SJ,Kindler J,Ruhrmann S,Uhlhaas PJ

更新日期：2016-01-28 00:00:00

abstract：:Outcome expectancies have been found to play important roles in addictive behaviors. Research has shown that implicit outcome expectancies (OE) were significantly correlated with Internet gaming behaviors among players with Internet gaming disorder (IGD). However, few empirical studies have further examined the relati...

journal_title：Frontiers in psychiatry

authors： Hou S,Fang X,Zhou N,Cai P

更新日期：2020-04-29 00:00:00

abstract：:Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association. Patients and methods: Data for this study were obtained from a population-based cohort study (the...

journal_title：Frontiers in psychiatry

authors： Stanikova D,Luck T,Pabst A,Bae YJ,Hinz A,Glaesmer H,Stanik J,Sacher J,Engel C,Enzenbach C,Wirkner K,Ceglarek U,Thiery J,Kratzsch J,Riedel-Heller SG

更新日期：2019-07-04 00:00:00

abstract：:The gut microbiota are known to have a profound influence on both mucosal and systemic immunity and are important for gastrointestinal (GI) function. In addition, new evidence shows that the microbiota significantly influence neurodevelopment and behavior. Immune dysfunction and GI distress are extremely common in ind...

journal_title：Frontiers in psychiatry

authors： Hughes HK,Ashwood P

更新日期：2018-11-26 00:00:00

abstract：:Japan recently ordered a string of death sentences for offenders with mental illness. Based on the verdicts, we describe cases where one or more psychiatrists conducted psychiatric evaluations for several months and testified in lay judge courts. We compared these cases with those in which the death penalty was avoide...

journal_title：Frontiers in psychiatry

authors： Kashiwagi H,Hirabayashi N

更新日期：2018-11-02 00:00:00

abstract：:Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to treat cocaine addiction, but the paucity of molecules co-activat...

journal_title：Frontiers in psychiatry

authors： Shen Q,Deng Y,Ciccocioppo R,Cannella N

更新日期：2017-11-13 00:00:00

abstract：:Cognitive neuroscience enables us now to decompose major depressive disorder into dysfunctional component processes and relate these processes to specific neural substrates. This approach can be used to illuminate the biological basis of altered psychological processes in depression, including abnormal decision-making...

journal_title：Frontiers in psychiatry

authors： Howlett JR,Paulus MP

更新日期：2013-11-08 00:00:00

abstract：:Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

journal_title：Frontiers in psychiatry

authors： Menke A

更新日期：2019-02-28 00:00:00

abstract：:Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be a major cognitive deficit independently caused by depression at acute episodes of MDD. Method: A comprehensive neurocognitive test battery was used to assess the executiv...

journal_title：Frontiers in psychiatry

authors： Liu J,Dong Q,Lu X,Sun J,Zhang L,Wang M,Wan P,Guo H,Zhao F,Ju Y,Yan D,Li H,Fang H,Guo W,Liao M,Zhang X,Zhang Y,Liu B,Li L

更新日期：2019-11-12 00:00:00

abstract：:Objective: Predicting who will be a placebo responder is a prerequisite to maximize placebo effects in pain treatment and to minimize them in clinical trials. First evidence exists that genetics could affect placebo effects. However, a classical twin study to estimate the relative contribution of genetic influences co...

journal_title：Frontiers in psychiatry

authors： Weimer K,Hahn E,Mönnikes N,Herr AK,Stengel A,Enck P

更新日期：2019-09-18 00:00:00

abstract：:Globally, 52.9 million children under the age of 5 experience a developmental disability, such as sensory impairment, intellectual disability, and autism spectrum disorders. Of these 95% live in low-and-middle-income countries. Most of these children lack access to care. In light of the growing evidence that caregiver...

journal_title：Frontiers in psychiatry

authors： Salomone E,Pacione L,Shire S,Brown FL,Reichow B,Servili C

更新日期：2019-11-11 00:00:00

abstract：:In this short review, we want to summarize the current findings on the role of vitamin-D in multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted hypovitaminosis-D as a potential environmental risk factor for a variety of conditions such as MS, asthma, cardiovascular disease, and, more rece...

journal_title：Frontiers in psychiatry

authors： Kočovská E,Gaughran F,Krivoy A,Meier UC

更新日期：2017-03-27 00:00:00

abstract：:Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medicine. We present the first urinary metabolomics biomarker study of childhood aggression. We aim to examine the association of urinary metabolites and neurotransmitter ratios involved in key metabolic and neurotransmitter ...

journal_title：Frontiers in psychiatry

authors： Hagenbeek FA,Roetman PJ,Pool R,Kluft C,Harms AC,van Dongen J,Colins OF,Talens S,van Beijsterveldt CEM,Vandenbosch MMLJZ,de Zeeuw EL,Déjean S,Fanos V,Ehli EA,Davies GE,Hottenga JJ,Hankemeier T,Bartels M,Vermeiren RRJM

更新日期：2020-03-31 00:00:00

abstract：:Psychological stress is recognized as a major modifiable risk factor for adult non-communicable disease (NCD) that includes depression, type 2 diabetes mellitus, and cardiovascular disease. Dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity resulting in either exaggerated or blunted cortisol responses...

journal_title：Frontiers in psychiatry

authors： Krishnaveni GV,Srinivasan K

更新日期：2019-10-29 00:00:00

abstract：:The progress of developing effective interventions against psychiatric disorders has been limited due to a lack of understanding of the underlying cellular and functional mechanisms. Recent research findings focused on exploring novel causes of psychiatric disorders have highlighted the importance of the axonal initia...

journal_title：Frontiers in psychiatry

authors： Hsu WC,Nilsson CL,Laezza F

更新日期：2014-08-21 00:00:00