Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors.

abstract：Objective:Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or s...

journal_title：Frontiers in psychiatry

authors： Simmons Z,Erickson LD,Hedges D,Kay DB

更新日期：2020-09-18 00:00:00

abstract：:Burnout syndrome is a state of total exhaustion related to work conditions and stress from work. Recent findings suggest that logotherapy and the concepts of existential meaning and life fulfilment could provide a useful framework for explaining and potentially preventing burnout. This review article summarizes and re...

journal_title：Frontiers in psychiatry

authors： Riethof N,Bob P

更新日期：2019-06-14 00:00:00

abstract：:Objective: Despite the fact that autism spectrum disorder (ASD) is a common psychiatric diagnosis, knowledge about the special behavioral and neurobiological female phenotype is still scarce. The present study aimed to investigate neural correlates of empathy for physical and social pain and to assess the impact of eg...

journal_title：Frontiers in psychiatry

authors： Stroth S,Paye L,Kamp-Becker I,Wermter AK,Krach S,Paulus FM,Müller-Pinzler L

更新日期：2019-06-18 00:00:00

abstract：:Autism spectrum disorder (ASD) and schizophrenia (SZ) are heterogenous neurodevelopmental disorders that overlap in symptom presentation. The purpose of this study was to specify overlapping symptom domains and to identify symptoms that can reliably differentiate adults with ASD (n = 53), SZ (n = 39), and typical deve...

journal_title：Frontiers in psychiatry

authors： Trevisan DA,Foss-Feig JH,Naples AJ,Srihari V,Anticevic A,McPartland JC

更新日期：2020-06-11 00:00:00

abstract：:Background: Young adults regularly using cannabis represent a uniquely vulnerable yet heterogeneous cohort. Few studies have examined user profiles using cannabis use motives and expectations. The association between user profiles and psychosocial functioning among only regular users remains unexplored. This explorati...

journal_title：Frontiers in psychiatry

authors： Amiet D,Youssef GJ,Hagg LJ,Lorenzetti V,Parkes L,Solowij N,Yücel M

更新日期：2020-12-15 00:00:00

abstract：:In a group of 1066 heroin addicts, who were seeking treatment for opioid agonist treatment, we looked for differences in historical, demographic, and clinical characteristics, between patients with different levels of awareness of illness (insight). The results showed that, in the cohort studied, a majority of subject...

journal_title：Frontiers in psychiatry

authors： Maremmani AG,Rovai L,Rugani F,Pacini M,Lamanna F,Bacciardi S,Perugi G,Deltito J,Dell'osso L,Maremmani I

更新日期：2012-07-09 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...

journal_title：Frontiers in psychiatry

authors： Fan Z,Yang J,Zeng C,Xi C,Wu G,Guo S,Xue Z,Liu Z,Tao H

更新日期：2020-10-27 00:00:00

abstract：Background:Attentional dysfunctions constitute core cognitive symptoms in schizophrenia, but the precise underlying neurocognitive mechanisms remain to be elucidated. Methods:In this randomized, double-blind, sham-controlled study, we applied, for the first time, a theoretically grounded modeling approach based on Bun...

journal_title：Frontiers in psychiatry

authors： Gögler N,Papazova I,Oviedo-Salcedo T,Filipova N,Strube W,Funk J,Müller HJ,Finke K,Hasan A

更新日期：2017-11-29 00:00:00

abstract：:Background: COVID-19 affects not only patients' physical health but also their mental health. For the general public, although their physical health may not be directly affected, their mental health may be affected by stress, anxiety, and social panic caused by COVID-19. Controlling the pandemic should focus on not on...

journal_title：Frontiers in psychiatry

authors： Wang S,Feng K,Zhang Y,Liu J,Wang W,Li Y

更新日期：2020-11-12 00:00:00

abstract：:The nucleus accumbens (NAc) plays an important role in the reward circuit, and abnormal regional activities of the reward circuit have been reported in various psychiatric disorders including somatization disorder (SD). However, few researches are designed to analyze the NAc connectivity in SD. This study was designed...

journal_title：Frontiers in psychiatry

authors： Ou Y,Su Q,Liu F,Ding Y,Chen J,Zhang Z,Zhao J,Guo W

更新日期：2019-08-16 00:00:00

abstract：:Very-brief, web-based alcohol interventions have great potential due to their convenience, ease of dissemination, and college students' stated preference for this intervention modality. To address the efficacy of these interventions, we conducted a review of the literature to identify randomized controlled trials (RCT...

journal_title：Frontiers in psychiatry

authors： Leeman RF,Perez E,Nogueira C,DeMartini KS

更新日期：2015-09-28 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

journal_title：Frontiers in psychiatry

authors： Xu J,Fregni F,Brody AL,Rahman AS

更新日期：2013-09-20 00:00:00

abstract：:Abnormal amplitude of low-frequency fluctuation has been implicated in heroin addiction. However, previous studies lacked consistency and didn't consider the impact of confounding factors such as methadone and alcohol. Fifty-one heroin-dependent (HD) individuals and 40 healthy controls underwent resting-state function...

journal_title：Frontiers in psychiatry

authors： Luo J,Yang R,Yang W,Duan C,Deng Y,Zhang J,Chen J,Liu J

更新日期：2020-07-03 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：:Introduction: Although binge eating disorder (BED) is an eating disorder and obesity is a clinical disease, it is known that both conditions present overlapped symptoms related to, at least partially, the disruption of homeostatic and hedonistic eating behavior pathways. Therefore, the understanding of neural substrat...

journal_title：Frontiers in psychiatry

authors： Antunes LC,Elkfury JL,Parizotti CS,Brietzke AP,Bandeira JS,Torres ILDS,Fregni F,Caumo W

更新日期：2020-10-14 00:00:00

abstract：:Objective: This study aims to understand the impact of negative life experience (NLE) in auditory hallucinations (AHs) and explain the heterogeneity in phenomenology of auditory verbal hallucinations (AVHs). Method: In depth interviews were conducted with 21 individuals (7 males and 14 females) experiencing AHs and ac...

journal_title：Frontiers in psychiatry

authors： Vallath S,Luhrmann T,Bunders J,Ravikant L,Gopikumar V

更新日期：2018-10-30 00:00:00

abstract：:New models of care aimed at reinforcing the outpatient sector have been introduced in Germany over the last few years. Initially, a subscription-based model ("integrated care") was introduced in 2012 in the Immanuel Klinik Rüdersdorf, wherein patients had to actively subscribe to the integrated care program. This inte...

journal_title：Frontiers in psychiatry

authors： Wullschleger A,Wosniok W,Timm J,Heinze M

更新日期：2017-10-05 00:00:00

abstract：:Neuroimaging holds the promise that it may one day aid the clinical assessment of individual psychiatric patients. However, the vast majority of studies published so far have been based on average differences between groups, which do not permit accurate inferences at the level of the individual. We examined the potent...

journal_title：Frontiers in psychiatry

authors： Tognin S,Pettersson-Yeo W,Valli I,Hutton C,Woolley J,Allen P,McGuire P,Mechelli A

更新日期：2014-01-29 00:00:00

abstract：Background:The quality of life (QOL) of patients with methamphetamine use disorder (MAUD) is increasingly recognized as an important outcome. Previous studies have found that impulsivity is negatively associated with QOL in mental disorders, but this relationship is rarely confirmed in patients with MAUD. We hypothesiz...

journal_title：Frontiers in psychiatry

authors： Wang Y,Zuo J,Hao W,Shen H,Zhang X,Deng Q,Liu M,Zhao Z,Zhang L,Zhou Y,Li M,Liu T,Zhang X

更新日期：2020-09-30 00:00:00

abstract：:Background: As refugee numbers grow worldwide, understanding prevalence and determinants of mental illness in this population becomes increasingly important. Methods: We used longitudinal data to examine the initial years of resettlement in Australian refugees with a focus on ethnic-like social support. Three annual w...

journal_title：Frontiers in psychiatry

authors： Cooper S,Enticott JC,Shawyer F,Meadows G

更新日期：2019-08-02 00:00:00

abstract：:Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...

journal_title：Frontiers in psychiatry

authors： Yang W,Yang R,Luo J,He L,Liu J,Zhang J

更新日期：2018-08-31 00:00:00

abstract：Background:Anorexia nervosa (AN) is characterized by severe malnutrition as well as inefficiencies in neurocognitive functioning, which are believed to contribute to the maintenance of disordered eating. The aim of this study was to examine the impact of individual cognitive remediation therapy (CRT) on neurocognition ...

journal_title：Frontiers in psychiatry

authors： Leppanen J,Adamson J,Tchanturia K

更新日期：2018-03-20 00:00:00

abstract：Background:Contemporary psychiatric research focuses its attention on the patient's dysfunction of metacognition in relation to the basic cognitive processes of mental activity. The current study investigated dysfunctional metacognition in relation to self-monitoring of memory in patients diagnosed with schizophrenia. ...

journal_title：Frontiers in psychiatry

authors： Szczepanowski R,Cichoń E,Pasieczna AH,Gawęda Ł,Rosińczuk J

更新日期：2020-07-29 00:00:00

abstract：:Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice. We recently launched the Neuroscience Interest Group within the International Society of Addict...

journal_title：Frontiers in psychiatry

authors： Verdejo-Garcia A,Lorenzetti V,Manning V,Piercy H,Bruno R,Hester R,Pennington D,Tolomeo S,Arunogiri S,Bates ME,Bowden-Jones H,Campanella S,Daughters SB,Kouimtsidis C,Lubman DI,Meyerhoff DJ,Ralph A,Rezapour T,Tavakoli H

更新日期：2019-12-23 00:00:00

abstract：:One clue regarding the basis of cocaine-induced deficits in attentional processing is provided by the clinical findings of changes in the infants' startle response; observations buttressed by neurophysiological evidence of alterations in brainstem transmission time. Using the IV route of administration and doses that ...

journal_title：Frontiers in psychiatry

authors： Mactutus CF,Harrod SB,Hord LL,Moran LM,Booze RM

更新日期：2011-06-28 00:00:00

abstract：:Aim: Acute psychosis is not an uncommon presenting feature in immune-mediated encephalitides. Most patients improve if properly diagnosed and treated expediently with immunotherapy. Our study aimed to describe the frequency, clinical spectrum, and long-term outcomes in patients presenting with acute psychosis who have...

journal_title：Frontiers in psychiatry

authors： Tang C,Tan K,Lim G,Tan L,Tay KY,Kandiah N,Abdin E,Verma SK

更新日期：2019-12-13 00:00:00

abstract：:Molecular mechanisms in the brain are assumed to cause the symptoms and severity of neuropsychiatric disorders. This review concerns the elusive nature of relationships between the severity of depressive disorders and neuromolecular processes studied by positron emission tomography (PET). Recent PET studies of human d...

journal_title：Frontiers in psychiatry

authors： Smith DF,Jakobsen S

更新日期：2013-03-04 00:00:00

abstract：:Background: The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) is the most commonly used instrument to assess burnout. Although various factors have been reported to influence its validity, the influence of major depressive disorder (MDD) has not been previously considered. We developed this study to invest...

journal_title：Frontiers in psychiatry

authors： Trigo TR,de Freitas CCS,Wang YP,Ribeiro FG,de Lucia MCS,Siqueira JO,Iosifescu DV,Hallak JEC,Fraguas R

更新日期：2018-12-18 00:00:00

abstract：:Prolonged bedtime smartphone use is often associated with poor sleep quality and daytime dysfunction. In addition, the unstructured nature of smartphones may lead to excessive and uncontrolled use, which can be a cardinal feature of problematic smartphone use. This study was designed to investigate functional connecti...

journal_title：Frontiers in psychiatry

authors： Paik SH,Park CH,Kim JY,Chun JW,Choi JS,Kim DJ

更新日期：2019-07-23 00:00:00