Prolonged Bedtime Smartphone Use is Associated With Altered Resting-State Functional Connectivity of the Insula in Adult Smartphone Users.

abstract：BACKGROUND:Research has demonstrated a reduction in olfactory functioning in patients with schizophrenia. This research has led to examination of olfactory functioning in other mental disorders, such as depression. There is a great deal of variation in the results generated from such research, and it remains unclear as...

journal_title：Frontiers in psychiatry

authors： Taalman H,Wallace C,Milev R

更新日期：2017-09-28 00:00:00

abstract：:Inflammatory processes associated with persistent (chronic) infection have long been discussed as etiological factors in psychiatric disorders. Studies have found that people with major depression have higher levels of pro-inflammatory cytokines, for example, IL-1, IL-6, and tumor necrosis factor-alpha, and C-reactive...

journal_title：Frontiers in psychiatry

authors： Müller N

更新日期：2019-05-31 00:00:00

abstract：:Patients with severe mental disorders die on average 20 years prior to the general population. This mortality gap is mainly due to the higher prevalence of physical diseases and the adoption of unhealthy lifestyle behaviors.The LIFESTYLE trial aims to evaluate the efficacy of a new psychosocial group intervention (inc...

journal_title：Frontiers in psychiatry

authors： Sampogna G,Fiorillo A,Luciano M,Del Vecchio V,Steardo L Jr,Pocai B,Barone M,Amore M,Pacitti F,Dell'Osso L,Di Lorenzo G,Maj M,LIFESTYLE Working Group.

更新日期：2018-06-07 00:00:00

abstract：:Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

journal_title：Frontiers in psychiatry

authors： Menke A

更新日期：2019-02-28 00:00:00

abstract：:Burnout syndrome is a state of total exhaustion related to work conditions and stress from work. Recent findings suggest that logotherapy and the concepts of existential meaning and life fulfilment could provide a useful framework for explaining and potentially preventing burnout. This review article summarizes and re...

journal_title：Frontiers in psychiatry

authors： Riethof N,Bob P

更新日期：2019-06-14 00:00:00

abstract：:Background: Attenuated positive psychotic symptoms represent the defining features of the clinical high-risk for psychosis (CHR-P) criteria. The effectiveness of each available treatment for reducing attenuated positive psychotic symptoms remains undetermined. This network meta-analysis (NMA) investigates the consiste...

journal_title：Frontiers in psychiatry

authors： Davies C,Radua J,Cipriani A,Stahl D,Provenzani U,McGuire P,Fusar-Poli P

更新日期：2018-06-12 00:00:00

abstract：:In this short review, we want to summarize the current findings on the role of vitamin-D in multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted hypovitaminosis-D as a potential environmental risk factor for a variety of conditions such as MS, asthma, cardiovascular disease, and, more rece...

journal_title：Frontiers in psychiatry

authors： Kočovská E,Gaughran F,Krivoy A,Meier UC

更新日期：2017-03-27 00:00:00

abstract：Background:Depression is a leading cause of disability worldwide and is a major contributor to the overall global burden of disease, but its etiology is poorly understood. It has been reported that a disrupted biological rhythm, in terms of a shortened light duration and total darkness, can cause depression-like behavi...

journal_title：Frontiers in psychiatry

authors： Hu H,Kang C,Hou X,Zhang Q,Meng Q,Jiang J,Hao W

更新日期：2020-04-08 00:00:00

abstract：:The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms t...

journal_title：Frontiers in psychiatry

authors： Kelly RR,McDonald LT,Jensen NR,Sidles SJ,LaRue AC

更新日期：2019-04-09 00:00:00

abstract：:Introduction: Although binge eating disorder (BED) is an eating disorder and obesity is a clinical disease, it is known that both conditions present overlapped symptoms related to, at least partially, the disruption of homeostatic and hedonistic eating behavior pathways. Therefore, the understanding of neural substrat...

journal_title：Frontiers in psychiatry

authors： Antunes LC,Elkfury JL,Parizotti CS,Brietzke AP,Bandeira JS,Torres ILDS,Fregni F,Caumo W

更新日期：2020-10-14 00:00:00

abstract：:Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life. Consequently, current research is focus...

journal_title：Frontiers in psychiatry

authors： Benedetti F,Aggio V,Pratesi ML,Greco G,Furlan R

更新日期：2020-02-26 00:00:00

abstract：:Psychological stress is recognized as a major modifiable risk factor for adult non-communicable disease (NCD) that includes depression, type 2 diabetes mellitus, and cardiovascular disease. Dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity resulting in either exaggerated or blunted cortisol responses...

journal_title：Frontiers in psychiatry

authors： Krishnaveni GV,Srinivasan K

更新日期：2019-10-29 00:00:00

abstract：:Background: Catatonic phenomena such as stupor, mutism, stereotypy, echolalia, echopraxia, affective flattening, psychomotor deficits, and social withdrawal are characteristic symptoms of both schizophrenia and autism spectrum disorders (ASD), suggesting overlapping pathophysiological similarities such as altered glut...

journal_title：Frontiers in psychiatry

authors： Hefter D,Topor CE,Gass P,Hirjak D

更新日期：2019-04-12 00:00:00

abstract：:Our recent microarray study reported altered mRNA expression of several low density lipoprotein receptor-related proteins (LRP) associated with the first 4 years following diagnosis with schizophrenia. Whilst this finding is novel, apolipoprotein E (APOE), which mediates its activity through LRPs, has been reported by...

journal_title：Frontiers in psychiatry

authors： Gibbons AS,Thomas EA,Scarr E,Dean B

更新日期：2010-07-08 00:00:00

abstract：:The progress of developing effective interventions against psychiatric disorders has been limited due to a lack of understanding of the underlying cellular and functional mechanisms. Recent research findings focused on exploring novel causes of psychiatric disorders have highlighted the importance of the axonal initia...

journal_title：Frontiers in psychiatry

authors： Hsu WC,Nilsson CL,Laezza F

更新日期：2014-08-21 00:00:00

abstract：:Cognitive impairment is an important aspect of schizophrenia, where cognitive remediation therapy (CRT) is a promising treatment for improving cognitive functioning. While neurobiological dysfunction in schizophrenia has been the target of much research, the neural substrate of cognitive remediation and recovery has n...

journal_title：Frontiers in psychiatry

authors： Thorsen AL,Johansson K,Løberg EM

更新日期：2014-08-15 00:00:00

abstract：:Suicide is the most severe consequence of depression which has become a leading cause of disability and a global disease burden. Recent evidence indicates a central role of small molecules in the pathogenesis of depression and associated suicidal behaviors. However, there lacks a systemic exploration of small molecule...

journal_title：Frontiers in psychiatry

authors： Liu S

更新日期：2020-04-16 00:00:00

abstract：:This article discusses yoga as a potential tool for children to deal with stress and regulate themselves. Yoga provides training of mind and body to bring emotional balance. We argue that children and young people need such tools to listen inward to their bodies, feelings, and ideas. Yoga may assist them in developing...

journal_title：Frontiers in psychiatry

authors： Hagen I,Nayar US

更新日期：2014-04-02 00:00:00

abstract：:Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...

journal_title：Frontiers in psychiatry

authors： Yang W,Yang R,Luo J,He L,Liu J,Zhang J

更新日期：2018-08-31 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often co-occur and share neurocognitive deficits. One such shared impairment is in duration discrimination. However, no studies using functional magnetic resonance imaging (fMRI) have investigated whether these duration discrimination d...

journal_title：Frontiers in psychiatry

authors： Lukito SD,O'Daly OG,Lythgoe DJ,Whitwell S,Debnam A,Murphy CM,Ashwood K,Stoencheva V,Simonoff E,Rubia K

更新日期：2018-11-14 00:00:00

abstract：:Third-generation neuroimaging research has been enriched by advances in magnetic resonance spectroscopy (MRS) measuring the concentration of important neurotrasmitters, such as the inhibitory amino acid GABA. Here, we performed a systematic mini-review on brain MRS studies measuring GABA concentration in patients affe...

journal_title：Frontiers in psychiatry

authors： Chiapponi C,Piras F,Piras F,Caltagirone C,Spalletta G

更新日期：2016-04-19 00:00:00

abstract：:The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians remain divided regarding key issues such as whether or not cannabis is an independent cause of psychosis and schizophrenia. This paper reviews the field in detail, examining questions of ca...

journal_title：Frontiers in psychiatry

authors： Burns JK

更新日期：2013-10-14 00:00:00

abstract：:Several studies support currently the hypothesis that autism etiology is based on a polygenic and epistatic model. However, despite advances in epidemiological, molecular and clinical genetics, the genetic risk factors remain difficult to identify, with the exception of a few chromosomal disorders and several single g...

journal_title：Frontiers in psychiatry

authors： Tordjman S,Somogyi E,Coulon N,Kermarrec S,Cohen D,Bronsard G,Bonnot O,Weismann-Arcache C,Botbol M,Lauth B,Ginchat V,Roubertoux P,Barburoth M,Kovess V,Geoffray MM,Xavier J

更新日期：2014-08-04 00:00:00

abstract：:Objective: Despite the fact that autism spectrum disorder (ASD) is a common psychiatric diagnosis, knowledge about the special behavioral and neurobiological female phenotype is still scarce. The present study aimed to investigate neural correlates of empathy for physical and social pain and to assess the impact of eg...

journal_title：Frontiers in psychiatry

authors： Stroth S,Paye L,Kamp-Becker I,Wermter AK,Krach S,Paulus FM,Müller-Pinzler L

更新日期：2019-06-18 00:00:00

abstract：Objectives:Schizophrenia (SZ) is a complex psychiatric disorder that has a strong genetic basis. Dystrobrevin-binding protein 1 (DTNBP1) is one of the genes thought to be pivotal in regulating the glutamatergic system. Studies have suggested that variations in DTNBP1 confer susceptibility to SZ and clinical symptoms. H...

journal_title：Frontiers in psychiatry

authors： Yang Y,Zhang L,Guo D,Zhang L,Yu H,Liu Q,Su X,Shao M,Song M,Zhang Y,Ding M,Lu Y,Liu B,Li W,Yue W,Fan X,Yang G,Lv L

更新日期：2020-05-25 00:00:00

abstract：Background:Attentional dysfunctions constitute core cognitive symptoms in schizophrenia, but the precise underlying neurocognitive mechanisms remain to be elucidated. Methods:In this randomized, double-blind, sham-controlled study, we applied, for the first time, a theoretically grounded modeling approach based on Bun...

journal_title：Frontiers in psychiatry

authors： Gögler N,Papazova I,Oviedo-Salcedo T,Filipova N,Strube W,Funk J,Müller HJ,Finke K,Hasan A

更新日期：2017-11-29 00:00:00

abstract：:Overt aggression, increased anxiety, and dysfunctional fear processing are often observed in individuals with conduct disorder (CD) and attention-deficit hyperactivity disorder (ADHD). Methylphenidate (MPH), a psychostimulant increasing dopamine and noradrenaline tone, is effective in reducing aggression in both CD an...

journal_title：Frontiers in psychiatry

authors： Jager A,Kanters D,Geers F,Buitelaar JK,Kozicz T,Glennon JC

更新日期：2019-10-25 00:00:00

abstract：:Background: Job burnout has become an increasing prevailing phenomenon among nurses in both developed and developing countries. There is a paucity of research exploring the relationship between perceived stress (i.e., the level of one's perception or appraisal of stress rather than objective stressful events) and job ...

journal_title：Frontiers in psychiatry

authors： Song Y,Yang F,Sznajder K,Yang X

更新日期：2020-11-13 00:00:00

abstract：:One clue regarding the basis of cocaine-induced deficits in attentional processing is provided by the clinical findings of changes in the infants' startle response; observations buttressed by neurophysiological evidence of alterations in brainstem transmission time. Using the IV route of administration and doses that ...

journal_title：Frontiers in psychiatry

authors： Mactutus CF,Harrod SB,Hord LL,Moran LM,Booze RM

更新日期：2011-06-28 00:00:00

abstract：:The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...

journal_title：Frontiers in psychiatry

authors： Yang X,Tao H,Xiao L,Li C,Tang Y,Liu Y

更新日期：2018-08-21 00:00:00