Low Density Lipoprotein Receptor-Related Protein and Apolipoprotein E Expression is Altered in Schizophrenia.

abstract：:Objectives: This study aimed to examine the rate of remission in individuals experiencing early-onset poststroke depression (PSD) in China and to identify predictors of remission during a 3-month follow-up. This study also explored the interaction between cognitive impairment and depression. Methods: A total of 820 pa...

journal_title：Frontiers in psychiatry

authors： Huang J,Zhou FC,Guan B,Zhang N,Wang A,Yu P,Zhou L,Wang CY,Wang C

更新日期：2019-01-08 00:00:00

abstract：:The view that anatomically distinct memory systems differentially contribute to the development of drug addiction and relapse has received extensive support. The present brief review revisits this hypothesis as it was originally proposed 20 years ago (1) and highlights several recent developments. Extensive research e...

journal_title：Frontiers in psychiatry

authors： Goodman J,Packard MG

更新日期：2016-02-25 00:00:00

abstract：:Conscious attempts to regulate alcohol and drug use are often undermined by automatic attention and arousal processes that are activated in the context of salient cues. Response to these cues involves body and brain signals that are linked via dynamic feedback loops, yet no studies have targeted the cardiovascular sys...

journal_title：Frontiers in psychiatry

authors： Bates ME,Lesnewich LM,Uhouse SG,Gohel S,Buckman JF

更新日期：2019-09-05 00:00:00

abstract：:Throughout the world, drug and alcohol use has a clear adolescent onset (Degenhardt et al., 2008). Alcohol continues to be the most popular drug among teens and emerging adults, with almost a third of 12th graders and 40% of college students reporting recent binge drinking (Johnston et al., 2009, 2010), and marijuana ...

journal_title：Frontiers in psychiatry

authors： Lisdahl KM,Gilbart ER,Wright NE,Shollenbarger S

更新日期：2013-07-01 00:00:00

abstract：:Background: In Germany, people suffering from severe mental illness who have committed serious offenses and have considerably reduced or suspended criminal responsibility can be detained and treated in forensic psychiatric hospitals. In the German federal state of Baden-Wuerttemberg, all psychiatric hospitals includin...

journal_title：Frontiers in psychiatry

authors： Flammer E,Frank U,Steinert T

更新日期：2020-03-05 00:00:00

abstract：Background:Opiate addiction is a major health problem in many countries. A crucial component of the medical treatment is the management of highly aversive opiate withdrawal signs, which may otherwise lead to resumption of drug taking. In a medication-assisted treatment (MAT), methadone and buprenorphine have been imple...

journal_title：Frontiers in psychiatry

authors： Hassan R,Pike See C,Sreenivasan S,Mansor SM,Müller CP,Hassan Z

更新日期：2020-05-07 00:00:00

abstract：:Objective: The ACCESS treatment model offers assertive community treatment (ACT) embedded in an integrated care program to patients with severe psychotic disorders. Compared to standard care, it proved to be more effective in terms of service disengagement and other outcomes in patients with psychotic disorders over 1...

journal_title：Frontiers in psychiatry

authors： Schöttle D,Ruppelt F,Schimmelmann BG,Karow A,Bussopulos A,Gallinat J,Wiedemann K,Luedecke D,Rohenkohl AC,Huber CG,Bock T,Lambert M

更新日期：2019-10-24 00:00:00

abstract：:Translational research aiming to elucidate mediators and moderators of placebo and nocebo effects is highly relevant. This experimental study tested effects of a brief progressive muscle relaxation (PMR) exercise, designed to alter psychobiological stress parameters, on the magnitude of placebo and nocebo effects in a...

journal_title：Frontiers in psychiatry

authors： Elsenbruch S,Roderigo T,Enck P,Benson S

更新日期：2019-03-21 00:00:00

abstract：:Fragile X syndrome (FXS) is caused by the full mutation (>200 CGG repeats) in the Fragile X Mental Retardation 1 (FMR1) gene. It is the most common inherited cause of intellectual disability (ID) and autism. This review focuses on neuropsychiatric disorders frequently experienced by premutation carriers with 55 to 200...

journal_title：Frontiers in psychiatry

authors： Hagerman RJ,Protic D,Rajaratnam A,Salcedo-Arellano MJ,Aydin EY,Schneider A

更新日期：2018-11-13 00:00:00

abstract：:Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum. We here review recent neuroimaging research that indicates cerebellar contributions t...

journal_title：Frontiers in psychiatry

authors： Depping MS,Schmitgen MM,Kubera KM,Wolf RC

更新日期：2018-11-29 00:00:00

abstract：:Voxel-based morphometry (VBM) is a commonly used method to study volumetric variations on a whole brain basis. However, it is often criticized for potential confounds, mainly based on imperfect spatial registration. We therefore aimed to evaluate if VBM and "gold standard" manual volumetry are measuring the same effec...

journal_title：Frontiers in psychiatry

authors： Focke NK,Trost S,Paulus W,Falkai P,Gruber O

更新日期：2014-04-08 00:00:00

abstract：:Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique biomarker-guided experimental medicine trials, there are no such...

journal_title：Frontiers in psychiatry

authors： Joshi YB,Light GA

更新日期：2018-11-19 00:00:00

abstract：:Imaging studies of major depressive disorder (MDD) have demonstrated enhanced resting-state activity of the amygdala as well as exaggerated reactivity to negative emotional stimuli relative to healthy controls (HCs). However, the abnormalities in the intrinsic connectivity of the amygdala in MDD still remain unclear. ...

journal_title：Frontiers in psychiatry

authors： Ramasubbu R,Konduru N,Cortese F,Bray S,Gaxiola-Valdez I,Goodyear B

更新日期：2014-02-19 00:00:00

abstract：:One of the fundamental questions in neuroscience is how brain activity relates to conscious experience. Even though self-consciousness is considered an emergent property of the brain network, a quantum physics-based theory assigns a momentum of consciousness to the single neuron level. In this work, we present a brain...

journal_title：Frontiers in psychiatry

authors： Sánchez-Ramón S,Faure F

更新日期：2020-09-29 00:00:00

abstract：:Background: More information is needed about the efficacy and safety of long-term baclofen in the treatment of alcohol use disorders. The objective of this study was to assess the effect of treatment with tailored-dose baclofen on alcohol consumption in patients with alcohol use disorders followed for 3 years after fi...

journal_title：Frontiers in psychiatry

authors： Pinot J,Rigal L,Granger B,Sidorkiewicz S,Jaury P

更新日期：2018-10-08 00:00:00

abstract：Objective:Employment was associated with recovery in individuals with schizophrenia. Our study aimed to delineate the vocational profile and investigate factors associated with likelihood of employment in individuals with schizophrenia. Materials and Methods:276 community dwelling outpatients with schizophrenia were r...

journal_title：Frontiers in psychiatry

authors： Ang MS,Rekhi G,Lee J

更新日期：2020-08-27 00:00:00

abstract：:Background: Primary indicated prevention in individuals at-risk for psychosis has the potential to improve the outcomes of this disorder. The ability to detect the majority of at-risk individuals is the main barrier toward extending benefits for the lives of many adolescents and young adults. Current detection strateg...

journal_title：Frontiers in psychiatry

authors： Fusar-Poli P,Oliver D,Spada G,Patel R,Stewart R,Dobson R,McGuire P

更新日期：2019-03-13 00:00:00

abstract：Background:Gastric necrosis following acute gastric dilatation is rare but more common in females with eating disorders, such as anorexia nervosa or bulimia, during which patients often alternate restriction and binge eating behaviors. Case Presentation:A 37-year old female patient with a history of 15 years of bulimi...

journal_title：Frontiers in psychiatry

authors： Achamrah N,Grigioni S,Coëffier M,Ainseba N,Déchelotte P

更新日期：2020-07-31 00:00:00

abstract：:Abnormal functional connectivity (FC) within discrete brain networks is involved in the pathophysiology of obsessive-compulsive disorder (OCD) with inconsistent results. In the present study, we investigated the FC patterns of 40 drug-naive patients with OCD and 38 healthy controls (HCs) through an unbiased voxel-wise...

journal_title：Frontiers in psychiatry

authors： Cui G,Ou Y,Chen Y,Lv D,Jia C,Zhong Z,Yang R,Wang Y,Meng X,Cui H,Li C,Sun Z,Wang X,Guo W,Li P

更新日期：2020-03-03 00:00:00

abstract：:In the field of mental health, games and computerized games present questions about paradoxes, evidences, and challenges. This perspective article offers perspectives and personal opinion about these questions, evidences, and challenges with an objective of presenting several ideas and issues in this rapidly developin...

journal_title：Frontiers in psychiatry

authors： Desseilles M

更新日期：2016-07-04 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：:Background: Attention deficit and hyperactivity disorder (ADHD) is one of the most common mental disorders in childhood. Recently, several studies showed the high suicide risk of patients with ADHD; however, most of these studies had a cross-sectional design. Aims: The aim of the current research is to complete a syst...

journal_title：Frontiers in psychiatry

authors： Garas P,Balazs J

更新日期：2020-12-21 00:00:00

abstract：:Background: The outbreak of novel coronavirus disease (COVID-19) has brought serious psychological pressure to people, especially medical health staff. At present, there are few studies on insomnia and related factors of medical health staff in the middle and late stage of the epidemic of COVID-19. Therefore, the purp...

journal_title：Frontiers in psychiatry

authors： Liu D,Liu S,Zhu L,Li D,Huang D,Deng H,Guo H,Huang D,Liao Y,Mao Z,Miao Q,Liu W,Xiu M,Zhang X

更新日期：2020-12-07 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSE) are characterized by the misfolding of the host encoded prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)) which leads to the accumulation of β-sheet-rich fibrils and subsequent loss of neurons and synaptic functions. Although many compounds have been identified ...

journal_title：Frontiers in psychiatry

authors： Eiden M,Leidel F,Strohmeier B,Fast C,Groschup MH

更新日期：2012-02-17 00:00:00

abstract：:Very-brief, web-based alcohol interventions have great potential due to their convenience, ease of dissemination, and college students' stated preference for this intervention modality. To address the efficacy of these interventions, we conducted a review of the literature to identify randomized controlled trials (RCT...

journal_title：Frontiers in psychiatry

authors： Leeman RF,Perez E,Nogueira C,DeMartini KS

更新日期：2015-09-28 00:00:00

abstract：:Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have exa...

journal_title：Frontiers in psychiatry

authors： Cheung SG,Goldenthal AR,Uhlemann AC,Mann JJ,Miller JM,Sublette ME

更新日期：2019-02-11 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：:Prenatal infections have been linked to the development of schizophrenia (SCZ) and other neurodevelopmental disorders in the offspring, and work in animal models indicates that this is to occur through the maternal inflammatory response triggered by infection. Several studies in animal models demonstrated that acute i...

journal_title：Frontiers in psychiatry

authors： Aguilar-Valles A,Rodrigue B,Matta-Camacho E

更新日期：2020-08-21 00:00:00

abstract：Study Objectives:Obstructive sleep apnea (OSA) is common in children with Down syndrome (DS) and is associated with adverse health and cognitive outcomes. Daytime clinical assessment is poorly predictive of OSA, so regular screening with sleep studies is recommended. However, sleep studies are costly and not available ...

journal_title：Frontiers in psychiatry

authors： Grantham-Hill S,Evans HJ,Tuffrey C,Sanders E,Elphick HE,Gringras P,Kingshott RN,Martin J,Reynolds J,Joyce A,Hill CM,Spruyt K

更新日期：2020-04-28 00:00:00

abstract：:Objective: The purpose of this study was to investigate the influence of parenting style on children's behavior problems after the Great East Japan Earthquake in 2011. Methods: Participants were children exposed to the 2011 disaster at preschool age (n = 163). Data were collected from August 2012 to March 2013, and fr...

journal_title：Frontiers in psychiatry

authors： Miki T,Fujiwara T,Yagi J,Homma H,Mashiko H,Nagao K,Okuyama M

更新日期：2019-02-19 00:00:00