COX-2 Inhibitors, Aspirin, and Other Potential Anti-Inflammatory Treatments for Psychiatric Disorders.

abstract：:Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

journal_title：Frontiers in psychiatry

authors： Xu J,Fregni F,Brody AL,Rahman AS

更新日期：2013-09-20 00:00:00

abstract：:Investigation in posttraumatic stress disorder (PTSD) shows a negative association between patients' degrees of acceptance (the willingness to face unwanted private experiences while pursuing one's values and goals) and those of clinical symptom severity, suggesting that experiential acceptance is a protective factor ...

journal_title：Frontiers in psychiatry

authors： Jung WH,Kim NH

更新日期：2020-07-30 00:00:00

abstract：:Previous studies have reported an association between verbal abuse in early childhood and structural and functional alterations in the young adult brain, supporting the existence of critical periods in human brain development. In addition, exposure to verbal abuse in early childhood is strongly correlated with lifetim...

journal_title：Frontiers in psychiatry

authors： Shin DW,Yoon T,Jeong B

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:Evidence indicates that early life stress (ELS) can induce persistent changes in the hypothalamic-pituitary-adrenal (HPA) axis to respond to stress in the adult life that leads to depression. These appear to be related to the impairment of HPA hormones through binding to glucocorticoid (GR) and mineralocorti...

journal_title：Frontiers in psychiatry

authors： Baes Cv,Martins CM,Tofoli SM,Juruena MF

更新日期：2014-01-24 00:00:00

abstract：:Suicide is a serious public health issue worldwide, yet current clinical methods for assessing a person's risk of taking their own life remain unreliable and new methods for assessing suicide risk are being explored. The widespread adoption of electronic health records (EHRs) has opened up new possibilities for epidem...

journal_title：Frontiers in psychiatry

authors： Bittar A,Velupillai S,Downs J,Sedgwick R,Dutta R

更新日期：2020-11-27 00:00:00

abstract：:Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have exa...

journal_title：Frontiers in psychiatry

authors： Cheung SG,Goldenthal AR,Uhlemann AC,Mann JJ,Miller JM,Sublette ME

更新日期：2019-02-11 00:00:00

abstract：:Depression is one of the most prevalent and serious mental disorders with a worldwide significant health burden. Metabolic abnormalities and disorders in patients with depression have attracted great research attention. Thirty-six metabolic biomarkers of clinical plasma metabolomics were detected by platform technolog...

journal_title：Frontiers in psychiatry

authors： Gao Y,Xu T,Zhao YX,Ling-Hu T,Liu SB,Tian JS,Qin XM

更新日期：2020-07-15 00:00:00

abstract：:There is minimal knowledge about the impact of large-scale epidemics on community mental health, particularly during the acute phase. This gap in knowledge means we are critically ill-equipped to support communities as they face the unprecedented COVID-19 pandemic. This study aimed to provide data urgently needed to i...

journal_title：Frontiers in psychiatry

authors： Dawel A,Shou Y,Smithson M,Cherbuin N,Banfield M,Calear AL,Farrer LM,Gray D,Gulliver A,Housen T,McCallum SM,Morse AR,Murray K,Newman E,Rodney Harris RM,Batterham PJ

更新日期：2020-10-06 00:00:00

abstract：:Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) is a synthetic compound found in psychoactive "spice" products that activates cannabinoid receptors. Preclinical evidence suggests that exposure to synthetic cannabinoids increases 5-HT2A/2C receptor function in the brain, an effect which might contribute to psyc...

journal_title：Frontiers in psychiatry

authors： Elmore JS,Baumann MH

更新日期：2018-02-27 00:00:00

abstract：:Mental illnesses, among which depression and anxiety are most common, are the leading cause for permanent disability. It is of interest to know what case characteristics determine if a person returns to the work force in spite of mental illness to tailor specific interventions. So far, there has been little research i...

journal_title：Frontiers in psychiatry

authors： Behrens-Wittenberg E,Wedegaertner F

更新日期：2020-07-31 00:00:00

abstract：:Structure and function are closely related in the healthy human brain. In patients with chronic heroin exposure, brain imaging studies have identified long-lasting changes in gray matter (GM) volume. More recently, we showed that acute application of heroin in dependent patients results in hypoperfusion of fronto-temp...

journal_title：Frontiers in psychiatry

authors： Denier N,Schmidt A,Gerber H,Schmid O,Riecher-Rössler A,Wiesbeck GA,Huber CG,Lang UE,Radue EW,Walter M,Borgwardt S

更新日期：2013-10-21 00:00:00

abstract：Introduction:Visual impairment (VI) is associated with a variety of comorbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods:The point prevalence of self-reported VI in Germa...

journal_title：Frontiers in psychiatry

authors： Schuster AK,Tesarz J,Rezapour J,Beutel ME,Bertram B,Pfeiffer N

更新日期：2018-04-09 00:00:00

abstract：:Glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. Previous studies using proton functional magnetic resonance spectroscopy (1H fMRS) have demonstrated elevated cortical glutamate levels by 2-4% during visual and motor stimulation, relative to periods of no stimula...

journal_title：Frontiers in psychiatry

authors： Woodcock EA,Anand C,Khatib D,Diwadkar VA,Stanley JA

更新日期：2018-03-06 00:00:00

abstract：:The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms t...

journal_title：Frontiers in psychiatry

authors： Kelly RR,McDonald LT,Jensen NR,Sidles SJ,LaRue AC

更新日期：2019-04-09 00:00:00

abstract：:Mental imagery, seeing with the mind's eyes, can induce stronger positive as well as negative affect compared to verbal processing. Given this emotion-amplifying effect, it appears likely that mental images play an important role in affective disorders. According to the subcomponents model of depression, depressed moo...

journal_title：Frontiers in psychiatry

authors： Görgen SM,Joormann J,Hiller W,Witthöft M

更新日期：2015-07-07 00:00:00

abstract：:Background: Unlike other episodic sleep disorders in childhood, there are no agreed severity indices for rhythmic movement disorder. While movements can be characterized in detail by polysomnography, in our experience most children inhibit rhythmic movement during polysomnography. Actigraphy and home video allow asses...

journal_title：Frontiers in psychiatry

authors： Gall M,Kohn B,Wiesmeyr C,van Sluijs RM,Wilhelm E,Rondei Q,Jäger L,Achermann P,Landolt HP,Jenni OG,Riener R,Garn H,Hill CM

更新日期：2019-10-16 00:00:00

abstract：Background:Contemporary psychiatric research focuses its attention on the patient's dysfunction of metacognition in relation to the basic cognitive processes of mental activity. The current study investigated dysfunctional metacognition in relation to self-monitoring of memory in patients diagnosed with schizophrenia. ...

journal_title：Frontiers in psychiatry

authors： Szczepanowski R,Cichoń E,Pasieczna AH,Gawęda Ł,Rosińczuk J

更新日期：2020-07-29 00:00:00

abstract：:Background: The personality trait neuroticism has been implicated in a poor response to stress, may relate to increased concentrations of cytokines and the development of depression. Inflammatory mechanisms may also be associated with the onset, severity and symptoms of depression. Both are related to poor antidepress...

journal_title：Frontiers in psychiatry

authors： Schmidt FM,Sander C,Minkwitz J,Mergl R,Dalton B,Holdt LM,Teupser D,Hegerl U,Himmerich H

更新日期：2018-11-20 00:00:00

abstract：:Diminished orienting to social stimuli, and particularly to faces, is a core feature of autism spectrum disorders (ASDs). Impaired face processing has been linked to atypical attention processes that trigger a cascade of pathological development contributing to impaired social communication. The aim of the present stu...

journal_title：Frontiers in psychiatry

authors： Bochet A,Franchini M,Kojovic N,Glaser B,Schaer M

更新日期：2021-01-13 00:00:00

abstract：:Socioeconomic status is a strong predictor of normative development and well-being in young people. It is well-known that growing up in a socioeconomically disadvantaged context may lead to negative outcomes, both in childhood and in adulthood. Early intervention and prevention programmes are crucial for building resi...

journal_title：Frontiers in psychiatry

authors： Kara B,Morris R,Brown A,Wigglesworth P,Kania J,Hart A,Mezes B,Cameron J,Eryigit-Madzwamuse S

更新日期：2021-01-14 00:00:00

abstract：:Background: The issue of treatment resistance in eating disorder care is controversial. Prior research has identified multiple failed treatment attempts as a common criterion for severe and enduring anorexia nervosa, but little is known about patients who have multiple failed treatment attempts. This study was designe...

journal_title：Frontiers in psychiatry

authors： Smith S,Woodside DB

更新日期：2021-01-08 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：Introduction:Although research over the past decade has resulted in significantly increased knowledge about distal risk factors for non-suicidal self-injury (NSSI), little is known about short-term (proximal) factors that predict NSSI thoughts and behaviors. Drawing on contemporaneous theories of NSSI, as well as the c...

journal_title：Frontiers in psychiatry

authors： Kiekens G,Hasking P,Nock MK,Boyes M,Kirtley O,Bruffaerts R,Myin-Germeys I,Claes L

更新日期：2020-03-20 00:00:00

abstract：Objective:Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or s...

journal_title：Frontiers in psychiatry

authors： Simmons Z,Erickson LD,Hedges D,Kay DB

更新日期：2020-09-18 00:00:00

abstract：Objectives:Schizophrenia (SZ) is a complex psychiatric disorder that has a strong genetic basis. Dystrobrevin-binding protein 1 (DTNBP1) is one of the genes thought to be pivotal in regulating the glutamatergic system. Studies have suggested that variations in DTNBP1 confer susceptibility to SZ and clinical symptoms. H...

journal_title：Frontiers in psychiatry

authors： Yang Y,Zhang L,Guo D,Zhang L,Yu H,Liu Q,Su X,Shao M,Song M,Zhang Y,Ding M,Lu Y,Liu B,Li W,Yue W,Fan X,Yang G,Lv L

更新日期：2020-05-25 00:00:00

abstract：:Background: Treatment of borderline personality disorder (BPD) in publicly funded mental health services generally use approaches based on medical interventions and generic case management. Specific psychological therapies developed for BPD may be more effective but have rarely been evaluated in routine clinical pract...

journal_title：Frontiers in psychiatry

authors： Carlyle D,Green R,Inder M,Porter R,Crowe M,Mulder R,Frampton C

更新日期：2020-11-12 00:00:00

abstract：Background:Neuropsychological studies have revealed that patients with schizophrenia (SZ) have facial recognition difficulties and a reduced visual evoked N170 response to human faces. However, detailed neurophysiological evidence of this face processing deficit in SZ with a higher spatial resolution has yet to be acqu...

journal_title：Frontiers in psychiatry

authors： Ohara N,Hirano Y,Oribe N,Tamura S,Nakamura I,Hirano S,Tsuchimoto R,Ueno T,Togao O,Hiwatashi A,Nakao T,Onitsuka T

更新日期：2020-09-03 00:00:00

abstract：:Refinements in the methods of diagnosis for psychiatric disorders are critically needed. These new methods should be based on objectively measured brain characteristics that provide clinically useful information. Studying the brain with respect to psychiatric disorders, however, faces numerous challenges. Utilizing te...

journal_title：Frontiers in psychiatry

authors： Kozel FA

更新日期：2010-10-20 00:00:00

abstract：:Computational methods are increasingly being applied to the study of psychiatric disorders. Often, this involves fitting models to the behavior of individuals with subclinical character traits that are known vulnerability factors for the development of psychiatric conditions. Anxiety disorders can be examined with ref...

journal_title：Frontiers in psychiatry

authors： Raymond JG,Steele JD,Seriès P

更新日期：2017-01-23 00:00:00

abstract：:Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We...

journal_title：Frontiers in psychiatry

authors： Térémetz M,Carment L,Brénugat-Herne L,Croca M,Bleton JP,Krebs MO,Maier MA,Amado I,Lindberg PG

更新日期：2017-07-10 00:00:00