Revisiting the Basic Symptom Concept: Toward Translating Risk Symptoms for Psychosis into Neurobiological Targets.

abstract：Background:Loss aversion is a central and well operationalized trait behavior that describes the tendency for humans to strongly prefer avoiding losses to making equivalent gains. Human decision-making is thus biased toward safer choices. Aim:The aim of this study was to explore the relationship between loss aversion ...

journal_title：Frontiers in psychiatry

authors： Hadlaczky G,Hökby S,Mkrtchian A,Wasserman D,Balazs J,Machín N,Sarchiapone M,Sisask M,Carli V

更新日期：2018-04-05 00:00:00

abstract：Introduction:Although research over the past decade has resulted in significantly increased knowledge about distal risk factors for non-suicidal self-injury (NSSI), little is known about short-term (proximal) factors that predict NSSI thoughts and behaviors. Drawing on contemporaneous theories of NSSI, as well as the c...

journal_title：Frontiers in psychiatry

authors： Kiekens G,Hasking P,Nock MK,Boyes M,Kirtley O,Bruffaerts R,Myin-Germeys I,Claes L

更新日期：2020-03-20 00:00:00

abstract：:Betel quid (BQ) is one of the most commonly consumed psychoactive substances. It has been suggested to be associated with various health issues, especially oral cancer. Evidence also points to possible decreased cognitive functions after long-term BQ chewing, such as attention and inhibition control. The present study...

journal_title：Frontiers in psychiatry

authors： Yuan F,Kong L,Zhu X,Jiang C,Fang C,Liao W

更新日期：2017-08-03 00:00:00

abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) is known to modulate spontaneous neural network excitability. The cognitive improvement observed in previous trials raises the potential of this technique as a possible therapeutic tool for use in attention-deficit/hyperactivity disorder (ADHD) population. Howev...

journal_title：Frontiers in psychiatry

authors： Cosmo C,Ferreira C,Miranda JG,do Rosário RS,Baptista AF,Montoya P,de Sena EP

更新日期：2015-08-04 00:00:00

abstract：:The present study aims to analyze the clinical and socio-demographic characteristics of patients with obsessive-compulsive disorder (OCD) in comorbidity with schizotypal personality disorder (SPD), as well as the response rate to pharmacological treatments. OCD+SPD patients had a younger age at onset, a higher probabi...

journal_title：Frontiers in psychiatry

authors： Perris F,Fabrazzo M,De Santis V,Luciano M,Sampogna G,Fiorillo A,Catapano F

更新日期：2019-06-17 00:00:00

abstract：:Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be a major cognitive deficit independently caused by depression at acute episodes of MDD. Method: A comprehensive neurocognitive test battery was used to assess the executiv...

journal_title：Frontiers in psychiatry

authors： Liu J,Dong Q,Lu X,Sun J,Zhang L,Wang M,Wan P,Guo H,Zhao F,Ju Y,Yan D,Li H,Fang H,Guo W,Liao M,Zhang X,Zhang Y,Liu B,Li L

更新日期：2019-11-12 00:00:00

abstract：:Glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. Previous studies using proton functional magnetic resonance spectroscopy (1H fMRS) have demonstrated elevated cortical glutamate levels by 2-4% during visual and motor stimulation, relative to periods of no stimula...

journal_title：Frontiers in psychiatry

authors： Woodcock EA,Anand C,Khatib D,Diwadkar VA,Stanley JA

更新日期：2018-03-06 00:00:00

abstract：:Objective: During the outbreak of the COVID-19 epidemic in China, breast cancer (BC) patients and healthcare workers faced several challenges, resulting in great psychological stress. We measured the psychological status of BC patients and female nurses and compared the severity within the two groups at the peak time-...

journal_title：Frontiers in psychiatry

authors： Cui Q,Cai Z,Li J,Liu Z,Sun S,Chen C,Wang G

更新日期：2020-12-15 00:00:00

abstract：:Suicide is the most severe consequence of depression which has become a leading cause of disability and a global disease burden. Recent evidence indicates a central role of small molecules in the pathogenesis of depression and associated suicidal behaviors. However, there lacks a systemic exploration of small molecule...

journal_title：Frontiers in psychiatry

authors： Liu S

更新日期：2020-04-16 00:00:00

abstract：:Clinicians and theorists have often proposed the two psychopathic subtypes of "primary" and "secondary" psychopathy, with recent research indicating some empirical support for both psychopathy subtypes, though the findings across studies are far from uniform. For the current study, latent profile analysis was used to ...

journal_title：Frontiers in psychiatry

authors： Lehmann RJB,Neumann CS,Hare RD,Biedermann J,Dahle KP,Mokros A

更新日期：2019-09-06 00:00:00

abstract：:Non-obscene socially inappropriate behavior (NOSI) is recognized as part of the tic disorder spectrum but has received little attention from researchers to date. A study in 87 patients with Tourette syndrome showed that comorbid attention-deficit/hyperactivity disorder (ADHD) and conduct disorder were also associated ...

journal_title：Frontiers in psychiatry

authors： Brandt V,Kerner Auch Koerner J,Palmer-Cooper E

更新日期：2019-09-13 00:00:00

abstract：Background:Prepulse inhibition (PPI) of the acoustic startle reflex is an operational measure of sensorimotor gating. The findings on PPI deficits in bipolar disorder (BD) are inconsistent among studies due to various confounding factors such as gender. This study aimed to assess sensorimotor gating deficits in patient...

journal_title：Frontiers in psychiatry

authors： Matsuo J,Ota M,Hidese S,Teraishi T,Hori H,Ishida I,Hiraishi M,Kunugi H

更新日期：2018-04-18 00:00:00

abstract：:Cognitive performance at illness onset may predict outcomes in first-episode psychosis (FEP), and the change in cognition may associate with clinical changes. Cognitive testing was administered to 54 FEP participants 2 months after entering treatment and to 39 participants after 1 year. We investigated whether baselin...

journal_title：Frontiers in psychiatry

authors： Lindgren M,Holm M,Kieseppä T,Suvisaari J

更新日期：2020-12-04 00:00:00

abstract：:What is the role and value of pleasure in addiction? Foddy and Savulescu (1) have claimed that substance use is just pleasure-oriented behavior. They describe addiction as "strong appetites toward pleasure" and argue that addicts suffer in significant part because of strong social and moral disapproval of lives domina...

journal_title：Frontiers in psychiatry

authors： Kennett J,Matthews S,Snoek A

更新日期：2013-09-25 00:00:00

abstract：:Background: Over the past 15 years, comparative assessments of psychoactive substance harms to both users and others have been compiled by addiction experts. None of these rankings however have included synthetic cannabinoids or non-opioid prescription analgesics (NOAs, e.g., gabapentinoids) despite evidence of increa...

journal_title：Frontiers in psychiatry

authors： Bonnet U,Specka M,Soyka M,Alberti T,Bender S,Grigoleit T,Hermle L,Hilger J,Hillemacher T,Kuhlmann T,Kuhn J,Luckhaus C,Lüdecke C,Reimer J,Schneider U,Schroeder W,Stuppe M,Wiesbeck GA,Wodarz N,McAnally H,Scherbaum N

更新日期：2020-10-26 00:00:00

abstract：Background:Attentional dysfunctions constitute core cognitive symptoms in schizophrenia, but the precise underlying neurocognitive mechanisms remain to be elucidated. Methods:In this randomized, double-blind, sham-controlled study, we applied, for the first time, a theoretically grounded modeling approach based on Bun...

journal_title：Frontiers in psychiatry

authors： Gögler N,Papazova I,Oviedo-Salcedo T,Filipova N,Strube W,Funk J,Müller HJ,Finke K,Hasan A

更新日期：2017-11-29 00:00:00

abstract：:Criminal responsibility assessment is undertaken by psychologists or psychiatrists to assess offenders' legal capacities, which vary among countries or regional legislations. There are two psychometric tools (i.e., checklists) validated for criminal responsibility assessment: the Roger Criminal Responsibility Scale, a...

journal_title：Frontiers in psychiatry

authors： Meyer LF,Leal CCS,Omena AAS,Mecler K,Valença AM

更新日期：2020-11-27 00:00:00

abstract：:It has been proposed that compulsive drug seeking reflects an underlying dysregulation in adaptive behavior that favors habitual (automatic and inflexible) over goal-directed (deliberative and highly flexible) action selection. Rodent studies have established that repeated exposure to cocaine or amphetamine facilitate...

journal_title：Frontiers in psychiatry

authors： Halbout B,Liu AT,Ostlund SB

更新日期：2016-03-21 00:00:00

abstract：:Timing is a fundamental and highly conserved mammalian capability, yet the underlying neural mechanisms are widely debated. Ramping activity of single neurons that gradually increase or decrease activity to encode the passage of time has been speculated to predict a behaviorally relevant temporal event. Cue-evoked low...

journal_title：Frontiers in psychiatry

authors： Parker KL

更新日期：2016-01-18 00:00:00

abstract：Background:High rates of non-psychotic psychopathological symptoms have been observed in clinical population at clinical high risk (CHR) for psychosis. These comorbid disorders affected the baseline functional level of CHR patients. However, little is known about the comorbid mental disorder in CHR individuals in non-c...

journal_title：Frontiers in psychiatry

authors： Shi J,Wang L,Yao Y,Su N,Zhan C,Mao Z,Zhao X

更新日期：2017-10-23 00:00:00

abstract：:Background: Unlike other episodic sleep disorders in childhood, there are no agreed severity indices for rhythmic movement disorder. While movements can be characterized in detail by polysomnography, in our experience most children inhibit rhythmic movement during polysomnography. Actigraphy and home video allow asses...

journal_title：Frontiers in psychiatry

authors： Gall M,Kohn B,Wiesmeyr C,van Sluijs RM,Wilhelm E,Rondei Q,Jäger L,Achermann P,Landolt HP,Jenni OG,Riener R,Garn H,Hill CM

更新日期：2019-10-16 00:00:00

abstract：:Increasing evidence suggests that binge eating-related disorders could be related to addiction-like eating patterns due to the addictive potential of hyperpalatable foods. Subsequently, important implications have been derived for treatment of those disorders and even political actions. However, studies on the prevale...

journal_title：Frontiers in psychiatry

authors： Meule A

更新日期：2011-11-03 00:00:00

abstract：:Throughout the world, drug and alcohol use has a clear adolescent onset (Degenhardt et al., 2008). Alcohol continues to be the most popular drug among teens and emerging adults, with almost a third of 12th graders and 40% of college students reporting recent binge drinking (Johnston et al., 2009, 2010), and marijuana ...

journal_title：Frontiers in psychiatry

authors： Lisdahl KM,Gilbart ER,Wright NE,Shollenbarger S

更新日期：2013-07-01 00:00:00

abstract：:This study compares the impact of repeated injections of baclofen (an agonist of GABAB receptors) or diazepam (a benzodiazepine having an agonist action on GABAA receptors) given during the alcohol-withdrawal period on the stress-induced restoration of alcohol-seeking behavior and hypothalamic-pituitary-adrenal (HPA) ...

journal_title：Frontiers in psychiatry

authors： Rabat Y,Henkous N,Corio M,Nogues X,Beracochea D

更新日期：2019-04-16 00:00:00

abstract：Objective:There is increasing interest in the utility of gamma-band activity for assessing various brain functions, including perception, language, memory, and cognition. The auditory steady-state response (ASSR) involves neural activity in the brain elicited by trains of a click sound, and its maximum response is obta...

journal_title：Frontiers in psychiatry

authors： Hirano Y,Nakamura I,Tamura S,Onitsuka T

更新日期：2020-09-02 00:00:00

abstract：:Acute growth in negative affect is thought to play a major role in triggering relapse in opiate-dependent individuals. Consistent with this view, three lab studies have demonstrated that negative mood induction increases opiate craving in opiate-dependent individuals. The current study sought to confirm these effects ...

journal_title：Frontiers in psychiatry

authors： Hogarth L,Hardy L,Bakou A,Mahlberg J,Weidemann G,Cashel S,Moustafa AA

更新日期：2019-05-15 00:00:00

abstract：Objectives:Schizophrenia (SZ) is a complex psychiatric disorder that has a strong genetic basis. Dystrobrevin-binding protein 1 (DTNBP1) is one of the genes thought to be pivotal in regulating the glutamatergic system. Studies have suggested that variations in DTNBP1 confer susceptibility to SZ and clinical symptoms. H...

journal_title：Frontiers in psychiatry

authors： Yang Y,Zhang L,Guo D,Zhang L,Yu H,Liu Q,Su X,Shao M,Song M,Zhang Y,Ding M,Lu Y,Liu B,Li W,Yue W,Fan X,Yang G,Lv L

更新日期：2020-05-25 00:00:00

abstract：INTRODUCTION:Emerging evidence indicates that nicotine dependence should be measured multidimensionally. A brief version of the Wisconsin Inventory of Smoking Dependence Motives (WISDM) has recently been developed in which the item count has been reduced from 68 to 37. The objectives of this study were to replicate the...

journal_title：Frontiers in psychiatry

authors： Ma JZ,Li MD,Payne TJ

更新日期：2012-04-26 00:00:00

abstract：:The dark triad (DT) traits-psychopathy, narcissism and Machiavellianism-have collectively been linked to reduced empathy and increased aggression; however, their association with distinct empathic subtypes remains unclear; and unique links to indirect relational aggression (IRA) have not been delineated. Moreover, whe...

journal_title：Frontiers in psychiatry

authors： Heym N,Firth J,Kibowski F,Sumich A,Egan V,Bloxsom CAJ

更新日期：2019-03-12 00:00:00

abstract：:The impact of COVID-19 on the elderly is devastating, and nursing homes are struggling to provide the best care to the most fragile. The urgency and severity of the pandemic forces the use of segregation in restricted areas and confinement in individual rooms as desperate strategies to avoid the spread of disease and ...

journal_title：Frontiers in psychiatry

authors： Muntsant A,Giménez-Llort L

更新日期：2020-11-24 00:00:00