Ranking the Harm of Psychoactive Drugs Including Prescription Analgesics to Users and Others-A Perspective of German Addiction Medicine Experts.

abstract：:Several studies support currently the hypothesis that autism etiology is based on a polygenic and epistatic model. However, despite advances in epidemiological, molecular and clinical genetics, the genetic risk factors remain difficult to identify, with the exception of a few chromosomal disorders and several single g...

journal_title：Frontiers in psychiatry

authors： Tordjman S,Somogyi E,Coulon N,Kermarrec S,Cohen D,Bronsard G,Bonnot O,Weismann-Arcache C,Botbol M,Lauth B,Ginchat V,Roubertoux P,Barburoth M,Kovess V,Geoffray MM,Xavier J

更新日期：2014-08-04 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：:Background: A growing body of research underlines that interpersonal trauma in childhood leads to heightened susceptibility for substance use disorders (SUDs) in later life. Little research has been conducted on parenting experiences of mothers in recovery from substance use, taking into account their own upbringing a...

journal_title：Frontiers in psychiatry

authors： Meulewaeter F,De Pauw SSW,Vanderplasschen W

更新日期：2019-10-18 00:00:00

abstract：:Abnormalities in EEG gamma band oscillations (GBO, 30-80 Hz) serve as a prominent biomarker of schizophrenia (Sz), associated with positive, negative, and cognitive symptoms. Chronic, subanesthetic administration of antagonists of N-methyl-D-aspartate receptors (NMDAR), such as ketamine, elicits behavioral effects, an...

journal_title：Frontiers in psychiatry

authors： McNally JM,McCarley RW,Brown RE

更新日期：2013-09-17 00:00:00

abstract：:Clinicians and theorists have often proposed the two psychopathic subtypes of "primary" and "secondary" psychopathy, with recent research indicating some empirical support for both psychopathy subtypes, though the findings across studies are far from uniform. For the current study, latent profile analysis was used to ...

journal_title：Frontiers in psychiatry

authors： Lehmann RJB,Neumann CS,Hare RD,Biedermann J,Dahle KP,Mokros A

更新日期：2019-09-06 00:00:00

abstract：:In a group of 1066 heroin addicts, who were seeking treatment for opioid agonist treatment, we looked for differences in historical, demographic, and clinical characteristics, between patients with different levels of awareness of illness (insight). The results showed that, in the cohort studied, a majority of subject...

journal_title：Frontiers in psychiatry

authors： Maremmani AG,Rovai L,Rugani F,Pacini M,Lamanna F,Bacciardi S,Perugi G,Deltito J,Dell'osso L,Maremmani I

更新日期：2012-07-09 00:00:00

abstract：:Background: Insufficient sleep is common in daily life and can lead to cognitive impairment. Sleep disturbance also exists in neuropsychiatric diseases. However, whether and how acute and chronic sleep loss affect brain morphology remain largely unknown. Methods: We used voxel-based morphology method to study the brai...

journal_title：Frontiers in psychiatry

authors： Dai XJ,Jiang J,Zhang Z,Nie X,Liu BX,Pei L,Gong H,Hu J,Lu G,Zhan Y

更新日期：2018-06-27 00:00:00

abstract：:Research lacks in verifying the nature of the relationship between mass media pressure, body image, and the risk of unhealthy eating behaviors. This study aimed to investigate whether the internalization of sociocultural norms, perceived pressure or searching for information about body image promoted by the mass media...

journal_title：Frontiers in psychiatry

authors： Izydorczyk B,Sitnik-Warchulska K,Lizińczyk S,Lipowska M

更新日期：2020-06-03 00:00:00

abstract：:There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...

journal_title：Frontiers in psychiatry

authors： Kent JS,Bolbecker AR,O'Donnell BF,Hetrick WP

更新日期：2015-12-18 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：:The nucleus accumbens (NAc) plays an important role in the reward circuit, and abnormal regional activities of the reward circuit have been reported in various psychiatric disorders including somatization disorder (SD). However, few researches are designed to analyze the NAc connectivity in SD. This study was designed...

journal_title：Frontiers in psychiatry

authors： Ou Y,Su Q,Liu F,Ding Y,Chen J,Zhang Z,Zhao J,Guo W

更新日期：2019-08-16 00:00:00

abstract：:The graph theoretical analysis of structural magnetic resonance imaging (MRI) data has received a great deal of interest in recent years to characterize the organizational principles of brain networks and their alterations in psychiatric disorders, such as schizophrenia. However, the characterization of networks in cl...

journal_title：Frontiers in psychiatry

authors： Edwin Thanarajah S,Han CE,Rotarska-Jagiela A,Singer W,Deichmann R,Maurer K,Kaiser M,Uhlhaas PJ

更新日期：2016-06-30 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：BACKGROUND:Electroconvulsive therapy (ECT) is effective in the treatment of major depressive disorder and schizophrenia in patients who are drug-naïve or less-receptive to antipsychotic drugs. Several studies have discussed the correlation between patient characteristics, input-current volume, and seizure duration. Acc...

journal_title：Frontiers in psychiatry

authors： Wang CC,Lin CH,Chiu YC,Tseng CC

更新日期：2013-12-23 00:00:00

abstract：:Involuntary autobiographical memories are mental representations of personally experienced past events that come to mind spontaneously, with no preceding attempt to recall them. They have been showed to be more frequent and more emotional in the psychosis continuum. Although schizophrenia is strongly associated with t...

journal_title：Frontiers in psychiatry

authors： Allé MC,Berna F,Danion JM,Berntsen D

更新日期：2020-10-09 00:00:00

abstract：:Childhood maltreatment (CM), including abuse and neglect, is a crucial factor that distorts child development. CM is associated with alterations in numerous brain regions, and may be associated with hormonal dysregulation. This study aimed to investigate differences in secretion patterns of cortisol (CT) and oxytocin ...

journal_title：Frontiers in psychiatry

authors： Mizushima SG,Fujisawa TX,Takiguchi S,Kumazaki H,Tanaka S,Tomoda A

更新日期：2015-12-11 00:00:00

abstract：:Defense mechanisms are psychological factors that influence emotional distress and quality of life. There are a number of measures assessing the construct of defense mechanisms, but only few available instruments reflect the gold-standard theoretical hierarchical organization of defenses. We report on the development ...

journal_title：Frontiers in psychiatry

authors： Di Giuseppe M,Perry JC,Lucchesi M,Michelini M,Vitiello S,Piantanida A,Fabiani M,Maffei S,Conversano C

更新日期：2020-08-26 00:00:00

abstract：:Background: Hypomanic episodes are characterized by increased goal-directed behavior and psychomotor agitation. While the affective, cognitive, and behavioral manifestations of such episodes are well-documented, their physiological influence on aerobic capacity and cardiopulmonary functioning are unknown. Methods: We ...

journal_title：Frontiers in psychiatry

authors： Shoval A,Armstrong HF,Vakhrusheva J,Ballon JS,Bartels MN,Kimhy D

更新日期：2018-12-21 00:00:00

abstract：:Alongside biological, psychological, and social risk factors, psychotic syndromes may be related to disturbances of neuronal migration. This highly complex process characterizes the developing brain of the fetus, the early postnatal brain, and the adult brain, as reflected by changes within the subventricular zone and...

journal_title：Frontiers in psychiatry

authors： Lucchese G,Flöel A,Stahl B

更新日期：2020-05-08 00:00:00

abstract：:Social cognition has become recognized as an important driver of functional outcomes and overall recovery in patients with schizophrenia, mediating the relationship between neurocognition and social functioning. Since antipsychotic therapy targeting remission of clinical symptoms has been shown to have a limited impac...

journal_title：Frontiers in psychiatry

authors： Javed A,Charles A

更新日期：2018-04-24 00:00:00

abstract：:Objective: Despite the fact that autism spectrum disorder (ASD) is a common psychiatric diagnosis, knowledge about the special behavioral and neurobiological female phenotype is still scarce. The present study aimed to investigate neural correlates of empathy for physical and social pain and to assess the impact of eg...

journal_title：Frontiers in psychiatry

authors： Stroth S,Paye L,Kamp-Becker I,Wermter AK,Krach S,Paulus FM,Müller-Pinzler L

更新日期：2019-06-18 00:00:00

abstract：:Background: Recently, many case-control studies have reported the association between 5-HTTLPR polymorphism and autism risk. However, the results are inconclusive and conflicting. To investigate the genetic association of 5-HTTLPR polymorphism and autism risk, we conducted a comprehensive meta-analysis based on previo...

journal_title：Frontiers in psychiatry

authors： Wang H,Yin F,Gao J,Fan X

更新日期：2019-02-13 00:00:00

abstract：Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...

journal_title：Frontiers in psychiatry

authors： Fan Z,Yang J,Zeng C,Xi C,Wu G,Guo S,Xue Z,Liu Z,Tao H

更新日期：2020-10-27 00:00:00

abstract：:Alcohol Use Disorder (AUD) is a chronic and relapsing condition characterized by harmful alcohol intake and behavioral-cognitive changes. AUD is the most common cause of liver disease in the Western world. Alcohol abstinence is the cornerstone of therapy in alcoholic patients affected with liver disease. Medical recom...

journal_title：Frontiers in psychiatry

authors： Mosoni C,Dionisi T,Vassallo GA,Mirijello A,Tarli C,Antonelli M,Sestito L,Rando MM,Tosoni A,De Cosmo S,Gasbarrini A,Addolorato G

更新日期：2018-10-01 00:00:00

abstract：:The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...

journal_title：Frontiers in psychiatry

authors： Yang X,Tao H,Xiao L,Li C,Tang Y,Liu Y

更新日期：2018-08-21 00:00:00

abstract：Background:High rates of non-psychotic psychopathological symptoms have been observed in clinical population at clinical high risk (CHR) for psychosis. These comorbid disorders affected the baseline functional level of CHR patients. However, little is known about the comorbid mental disorder in CHR individuals in non-c...

journal_title：Frontiers in psychiatry

authors： Shi J,Wang L,Yao Y,Su N,Zhan C,Mao Z,Zhao X

更新日期：2017-10-23 00:00:00

abstract：Background:There have been numerous studies investigating the relationship between nonsuicidal self-injury (NSSI) and suicidality. On the one side, NSSI is an important risk factor for suicidality, including suicidal thoughts and behaviors. On the other side, it has been suggested that one function of NSSI might be as ...

journal_title：Frontiers in psychiatry

authors： Kraus L,Schmid M,In-Albon T

更新日期：2020-06-03 00:00:00

abstract：Objectives:Many studies reported structural brain changes in patients with alcohol dependence (PADs). However, no studies identified structural correlates of apathy that might aggravate alcohol misuse. Here, we explored regional differences in cortical thickness in PADs relative to healthy controls (HCs), and examined ...

journal_title：Frontiers in psychiatry

authors： Yang K,Yang Q,Niu Y,Fan F,Chen S,Luo X,Tan S,Wang Z,Tong J,Yang F,Le TM,Li CR,Tan Y

更新日期：2020-05-05 00:00:00

abstract：:Bullying victimization by peers is highly prevalent in childhood and adolescence. There is convincing evidence that victimization is associated with adverse mental health consequences. In contrast, it has been found that perpetrators suffer no adverse mental health consequences. These findings originate from Western c...

journal_title：Frontiers in psychiatry

authors： Lin M,Wolke D,Schneider S,Margraf J

更新日期：2020-01-14 00:00:00

abstract：:Introduction: Clozapine is the most effective antipsychotic used for treatment resistant schizophrenia and recurrent suicidal behavior in schizophrenia or schizoaffective disorder. However, it has been underutilized due to its adverse reaction profile. Although clozapine is typically associated with neutropenia leadin...

journal_title：Frontiers in psychiatry

authors： Torrico T,Crandall RO,Meza C,Abdijadid S

更新日期：2020-10-14 00:00:00