Comorbidity of Obsessive-Compulsive Disorder and Schizotypal Personality Disorder: Clinical Response and Treatment Resistance to Pharmacotherapy in a 3-Year Follow-Up Naturalistic Study.

abstract：Background/Hypotheses:As risk factors for nonsuicidal self-injury (NSSI), most studies highlight the importance of internalising disorders, while only a few researches show the connection between externalising disorders and NSSI. Although some papers have introduced the idea that increasing prevalence rates of NSSI are...

journal_title：Frontiers in psychiatry

authors： Mészáros G,Győri D,Horváth LO,Szentiványi D,Balázs J

更新日期：2020-08-14 00:00:00

abstract：:The number of people with dementia worldwide is expected to increase to approximately 1.3 billion in 2050. Almost 90% of patients diagnosed with dementia suffer from behavioral and psychological symptoms of dementia (BPSD). BPSD causes and risk factors are multiple and complex and can be responsible for hospitalizatio...

journal_title：Frontiers in psychiatry

authors： Soares WB,Silvestre IT,Lima AMO,de Almondes KM

更新日期：2020-09-15 00:00:00

abstract：:Converging lines of evidence indicates that smoking and internet gaming disorder (IGD) affect spontaneous brain activity, respectively. However, little is known about whether these two factors work together on the human brain. In this study, we investigated the interaction between smoking and IGD on local spontaneous ...

journal_title：Frontiers in psychiatry

authors： Qiu X,Han X,Wang Y,Ding W,Sun Y,Zhou Y,Lei H,Lin F

更新日期：2020-12-03 00:00:00

abstract：:In the brain of female mammals, including humans, a number of physiological and behavioral changes occur as a result of sex hormone exposure. Estradiol and progesterone regulate several brain functions, including learning and memory. Sex hormones contribute to shape the central nervous system by modulating the formati...

journal_title：Frontiers in psychiatry

authors： Hansberg-Pastor V,González-Arenas A,Piña-Medina AG,Camacho-Arroyo I

更新日期：2015-11-20 00:00:00

abstract：:This paper focuses on depression that precedes an onset of manifest bipolar disorder as early stage bipolar disorder. First, we review how to pragmatically identify the clinical characteristics of patients presenting with an episode of depression who subsequently go on to develop episodes of mania or hypomania. The ex...

journal_title：Frontiers in psychiatry

authors： O'Donovan C,Alda M

更新日期：2020-06-11 00:00:00

abstract：:Alcohol use disorder (AUD) is a devastating public health problem in which both genetic and environmental factors play a role. Growing evidence supports that epigenetic regulation is one major mechanism in neuroadaptation that contributes to development of AUD. Meanwhile, epigenetic patterns can be modified by various...

journal_title：Frontiers in psychiatry

authors： Chen J,Hutchison KE,Bryan AD,Filbey FM,Calhoun VD,Claus ED,Lin D,Sui J,Du Y,Liu J

更新日期：2018-11-15 00:00:00

abstract：:Introduction: Previous studies on internet gaming disorder (IGD) have reported an association between personality traits and impulsive or problematic use of the internet or internet games, but the results obtained were inconsistent. Our study's hypothesis was that personality traits are associated with the individual'...

journal_title：Frontiers in psychiatry

authors： Seong W,Hong JS,Kim S,Kim SM,Han DH

更新日期：2019-08-28 00:00:00

abstract：:Background: Left-behind children (LBC) are becoming a widespread phenomenon and face higher risks of psychological and educational problems. Our study aimed to explore school bullying in LBC and examine the effectiveness of art therapy intervention for reducing bullying victimization affecting LBC in rural areas. Meth...

journal_title：Frontiers in psychiatry

authors： Yan H,Chen J,Huang J

更新日期：2019-02-07 00:00:00

abstract：:Very-brief, web-based alcohol interventions have great potential due to their convenience, ease of dissemination, and college students' stated preference for this intervention modality. To address the efficacy of these interventions, we conducted a review of the literature to identify randomized controlled trials (RCT...

journal_title：Frontiers in psychiatry

authors： Leeman RF,Perez E,Nogueira C,DeMartini KS

更新日期：2015-09-28 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting children, adolescents, and adults. Its etiology is not well understood, but it is increasingly believed to result from diverse pathophysiologies that affect the structure and function of specific brain circui...

journal_title：Frontiers in psychiatry

authors： Khadka S,Pearlson GD,Calhoun VD,Liu J,Gelernter J,Bessette KL,Stevens MC

更新日期：2016-07-25 00:00:00

abstract：:Childhood maltreatment (CM), including abuse and neglect, is a crucial factor that distorts child development. CM is associated with alterations in numerous brain regions, and may be associated with hormonal dysregulation. This study aimed to investigate differences in secretion patterns of cortisol (CT) and oxytocin ...

journal_title：Frontiers in psychiatry

authors： Mizushima SG,Fujisawa TX,Takiguchi S,Kumazaki H,Tanaka S,Tomoda A

更新日期：2015-12-11 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a disorder most frequently diagnosed in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion of patients discontinue treatment because of adverse events or insufficient improvement of symptoms. In addition,...

journal_title：Frontiers in psychiatry

authors： Sierawska A,Prehn-Kristensen A,Moliadze V,Krauel K,Nowak R,Freitag CM,Siniatchkin M,Buyx A

更新日期：2019-05-16 00:00:00

abstract：:Adenosine-to-inosine (A-to-I) RNA editing is a co-/posttranscriptional modification of double-stranded RNA, catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which results in recognition of inosine as guanosine by translational and splicing machinery causing potential recoding events in amin...

journal_title：Frontiers in psychiatry

authors： Dick ALW,Khermesh K,Paul E,Stamp F,Levanon EY,Chen A

更新日期：2019-04-26 00:00:00

abstract：:Prenatal infections have been linked to the development of schizophrenia (SCZ) and other neurodevelopmental disorders in the offspring, and work in animal models indicates that this is to occur through the maternal inflammatory response triggered by infection. Several studies in animal models demonstrated that acute i...

journal_title：Frontiers in psychiatry

authors： Aguilar-Valles A,Rodrigue B,Matta-Camacho E

更新日期：2020-08-21 00:00:00

abstract：:Bullying victimization by peers is highly prevalent in childhood and adolescence. There is convincing evidence that victimization is associated with adverse mental health consequences. In contrast, it has been found that perpetrators suffer no adverse mental health consequences. These findings originate from Western c...

journal_title：Frontiers in psychiatry

authors： Lin M,Wolke D,Schneider S,Margraf J

更新日期：2020-01-14 00:00:00

abstract：Study Objectives:Obstructive sleep apnea (OSA) is common in children with Down syndrome (DS) and is associated with adverse health and cognitive outcomes. Daytime clinical assessment is poorly predictive of OSA, so regular screening with sleep studies is recommended. However, sleep studies are costly and not available ...

journal_title：Frontiers in psychiatry

authors： Grantham-Hill S,Evans HJ,Tuffrey C,Sanders E,Elphick HE,Gringras P,Kingshott RN,Martin J,Reynolds J,Joyce A,Hill CM,Spruyt K

更新日期：2020-04-28 00:00:00

abstract：:The rapidly increasing number of patients with Alzheimer's disease (AD) worldwide has become a major public concern. Mild cognitive impairment (MCI), characterized with accelerated memory decline than normal aging, is a stage between cognitively unimpaired and dementia. Identification of MCI in the Alzheimer's continu...

journal_title：Frontiers in psychiatry

authors： Lin L,Xing G,Han Y

更新日期：2018-12-06 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：:Recent work on the mechanisms underlying auditory verbal hallucination (AVH) has been heavily informed by self-monitoring accounts that postulate defects in an internal monitoring mechanism as the basis of AVH. A more neglected alternative is an account focusing on defects in auditory processing, namely a spontaneous ...

journal_title：Frontiers in psychiatry

authors： Cho R,Wu W

更新日期：2013-11-27 00:00:00

abstract：Introduction:Although research over the past decade has resulted in significantly increased knowledge about distal risk factors for non-suicidal self-injury (NSSI), little is known about short-term (proximal) factors that predict NSSI thoughts and behaviors. Drawing on contemporaneous theories of NSSI, as well as the c...

journal_title：Frontiers in psychiatry

authors： Kiekens G,Hasking P,Nock MK,Boyes M,Kirtley O,Bruffaerts R,Myin-Germeys I,Claes L

更新日期：2020-03-20 00:00:00

abstract：:Patients with severe mental disorders die on average 20 years prior to the general population. This mortality gap is mainly due to the higher prevalence of physical diseases and the adoption of unhealthy lifestyle behaviors.The LIFESTYLE trial aims to evaluate the efficacy of a new psychosocial group intervention (inc...

journal_title：Frontiers in psychiatry

authors： Sampogna G,Fiorillo A,Luciano M,Del Vecchio V,Steardo L Jr,Pocai B,Barone M,Amore M,Pacitti F,Dell'Osso L,Di Lorenzo G,Maj M,LIFESTYLE Working Group.

更新日期：2018-06-07 00:00:00

abstract：:Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum. We here review recent neuroimaging research that indicates cerebellar contributions t...

journal_title：Frontiers in psychiatry

authors： Depping MS,Schmitgen MM,Kubera KM,Wolf RC

更新日期：2018-11-29 00:00:00

abstract：:Socioeconomic status is a strong predictor of normative development and well-being in young people. It is well-known that growing up in a socioeconomically disadvantaged context may lead to negative outcomes, both in childhood and in adulthood. Early intervention and prevention programmes are crucial for building resi...

journal_title：Frontiers in psychiatry

authors： Kara B,Morris R,Brown A,Wigglesworth P,Kania J,Hart A,Mezes B,Cameron J,Eryigit-Madzwamuse S

更新日期：2021-01-14 00:00:00

abstract：:Introduction: Chronic recreational methamphetamine use causes dopaminergic neurotoxicity, which has been linked to impairments in executive functioning. Within this functional domain, response selection and the resolution of associated conflicts have repeatedly been demonstrated to be strongly modulated by dopamine. Y...

journal_title：Frontiers in psychiatry

authors： Bensmann W,Ernst J,Rädle M,Opitz A,Beste C,Stock AK

更新日期：2019-11-19 00:00:00

abstract：:Introduction: Clozapine is the most effective antipsychotic used for treatment resistant schizophrenia and recurrent suicidal behavior in schizophrenia or schizoaffective disorder. However, it has been underutilized due to its adverse reaction profile. Although clozapine is typically associated with neutropenia leadin...

journal_title：Frontiers in psychiatry

authors： Torrico T,Crandall RO,Meza C,Abdijadid S

更新日期：2020-10-14 00:00:00

abstract：:There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...

journal_title：Frontiers in psychiatry

authors： Kent JS,Bolbecker AR,O'Donnell BF,Hetrick WP

更新日期：2015-12-18 00:00:00

abstract：:Background: Disrupted sleep is common among nursing home patients with dementia and is associated with increased agitation, depression, and cognitive impairment. Detecting and treating sleep problems in this population are therefore of great importance, albeit challenging. Systematic observation and objective recordin...

journal_title：Frontiers in psychiatry

authors： Hjetland GJ,Nordhus IH,Pallesen S,Cummings J,Tractenberg RE,Thun E,Kolberg E,Flo E

更新日期：2020-03-13 00:00:00

abstract：Background:Mobile phone addiction behaviors (MPAB) are extensively associated with several mental and sleep problems. Only a limited number of bidirectional longitudinal papers have focused on this field. This study aimed to examine the bidirectional associations of MPAB with mental distress, sleep disturbances, and sl...

journal_title：Frontiers in psychiatry

authors： Kang Y,Liu S,Yang L,Xu B,Lin L,Xie L,Zhang W,Zhang J,Zhang B

更新日期：2020-07-17 00:00:00

abstract：:Objective: The ACCESS treatment model offers assertive community treatment (ACT) embedded in an integrated care program to patients with severe psychotic disorders. Compared to standard care, it proved to be more effective in terms of service disengagement and other outcomes in patients with psychotic disorders over 1...

journal_title：Frontiers in psychiatry

authors： Schöttle D,Ruppelt F,Schimmelmann BG,Karow A,Bussopulos A,Gallinat J,Wiedemann K,Luedecke D,Rohenkohl AC,Huber CG,Bock T,Lambert M

更新日期：2019-10-24 00:00:00

abstract：:Background: The developmental period from 0 to 25 years is a vulnerable time during which children and young people experience many psychosocial and neurobiological changes and an increased incidence of mental illness. New clinical services for children and young people aged 0 to 25 years may represent a radical trans...

journal_title：Frontiers in psychiatry

authors： Fusar-Poli P

更新日期：2019-06-07 00:00:00