Tissue Distribution of Kir7.1 Inwardly Rectifying K+ Channel Probed in a Knock-in Mouse Expressing a Haemagglutinin-Tagged Protein.

abstract：INTRODUCTION:Near-infrared (NIR) imaging has emerged as a novel imaging modality for assessing lymphatic function in vivo. While the technique has provided quantitative data previously unavailable, questions remain in regards to the spatiotemporal capabilities of the approach. We address three of the more important iss...

journal_title：Frontiers in physiology

authors： Weiler M,Dixon JB

更新日期：2013-08-15 00:00:00

abstract：INTRODUCTION:Exercise reduces arterial and central venous blood pressures during recovery, which contributes to its valuable anti-hypertensive effects and to facilitating hypervolemia. Repeated sprint exercise potently improves metabolic function, but its cardiovascular effects (esp. hematological) are less well-charac...

journal_title：Frontiers in physiology

authors： Graham MJ,Lucas SJ,Francois ME,Stavrianeas S,Parr EB,Thomas KN,Cotter JD

更新日期：2016-05-31 00:00:00

abstract：:About 14% of veterans who suffer from Gulf war illness (GWI) complain of some form of gastrointestinal disorder but with no significant markers of clinical pathology. Our previous studies have shown that exposure to GW chemicals resulted in altered microbiome which was associated with damage associated molecular patte...

journal_title：Frontiers in physiology

authors： Kimono D,Sarkar S,Albadrani M,Seth R,Bose D,Mondal A,Li Y,Kar AN,Nagarkatti M,Nagarkatti P,Sullivan K,Janulewicz P,Lasley S,Horner R,Klimas N,Chatterjee S

更新日期：2019-10-14 00:00:00

abstract：:Spodoptera exigua and S. litura are two sympatric species in China and many other countries. Both moths employ a multiple component sex pheromone blend, including a common component Z9,E12-14:OAc, and two specific components Z9-14:OH and Z11-16:OAc for S. exigua, and one specific component Z9,E11-14:OAc for S. litura....

journal_title：Frontiers in physiology

authors： Yan Q,Liu XL,Wang YL,Tang XQ,Shen ZJ,Dong SL,Deng JY

更新日期：2019-09-27 00:00:00

abstract：:Introduction: Tilt tables enable early mobilization of patients by providing verticalization. But there is a high risk of orthostatic hypotension provoked by verticalization, especially after neurological diseases such as spinal cord injury. Robot-assisted tilt tables might be an alternative as they add passive roboti...

journal_title：Frontiers in physiology

authors： Sarabadani Tafreshi A,Riener R,Klamroth-Marganska V

更新日期：2016-12-09 00:00:00

abstract：:In this paper we develop a novel mathematical model of the insulin-TOR-MAPK signaling network that controls growth. Most data on the properties of the insulin and MAPK signaling networks are static and the responses to experimental interventions, such as knockouts, overexpression, and hormonal input are typically repo...

journal_title：Frontiers in physiology

authors： Nijhout HF,Callier V

更新日期：2013-09-12 00:00:00

abstract：:Early predispositions to preferentially orient toward cues associated with social partners have been documented in several vertebrate species including human neonates and domestic chicks. Human newborns at high familiar risk of Autism Spectrum Disorder (ASD) show differences in their attention toward these predisposed...

journal_title：Frontiers in physiology

authors： Lorenzi E,Pross A,Rosa-Salva O,Versace E,Sgadò P,Vallortigara G

更新日期：2019-04-30 00:00:00

abstract：:As clinicians attempt to understand the underlying reasons for the vulnerability of different regions of the developing brain to injury, it is apparent that little is known as to how hypoxia-ischemia may affect the cerebrovasculature in the developing infant. Most of the research investigating the pathogenesis of peri...

journal_title：Frontiers in physiology

authors： Baburamani AA,Ek CJ,Walker DW,Castillo-Melendez M

更新日期：2012-11-09 00:00:00

abstract：:Autophagy, or cellular self-eating, is a tightly regulated cellular pathway the main purpose of which is lysosomal degradation and subsequent recycling of cytoplasmic material to maintain normal cellular homeostasis. Defects in autophagy are linked to a variety of pathological states, including cancer. Cancer is the d...

journal_title：Frontiers in physiology

authors： Kondratskyi A,Yassine M,Kondratska K,Skryma R,Slomianny C,Prevarskaya N

更新日期：2013-10-02 00:00:00

abstract：:Immunity and cellular metabolism are tightly interconnected but it is not clear whether different pathogens elicit specific metabolic responses. To address this issue, we studied differential metabolic regulation in peripheral blood mononuclear cells (PBMCs) of healthy volunteers challenged by Candida albicans, Borrel...

journal_title：Frontiers in physiology

authors： Zhang X,Mardinoglu A,Joosten LAB,Kuivenhoven JA,Li Y,Netea MG,Groen AK

更新日期：2018-02-27 00:00:00

abstract：:In addition to its roles in the maintenance of interstitial fluid homeostasis and immunosurveillance, the lymphatic system has a critical role in regulating transport of dietary lipids to the blood circulation. Recent work within the past two decades has identified an important relationship between lymphatic dysfuncti...

journal_title：Frontiers in physiology

authors： Norden PR,Kume T

更新日期：2020-05-05 00:00:00

abstract：:Inflammation is a process whose main function is to fight against invading pathogens or foreign agents. Nonetheless, it is widely accepted that inflammation takes part in multiple processes in a physiological or pathophysiological context. Among these processes the inflammation has been closely related to bone metabol...

journal_title：Frontiers in physiology

authors： Alonso-Pérez A,Franco-Trepat E,Guillán-Fresco M,Jorge-Mora A,López V,Pino J,Gualillo O,Gómez R

更新日期：2018-05-08 00:00:00

abstract：:Spermatogenesis is a complicated process including spermatogonial stem cells self-renewal and differentiates into mature spermatozoa. MicroRNAs (miRNAs) as a class of small non-coding RNAs play a crucial role during the process of spermatogenesis. However, the function of a plenty of miRNAs on spermatogenesis and the ...

journal_title：Frontiers in physiology

authors： Gao H,Wen H,Cao C,Dong D,Yang C,Xie S,Zhang J,Huang X,Huang X,Yuan S,Dong W

更新日期：2019-06-18 00:00:00

abstract：:For many hereditary disorders, although the underlying genetic mutation may be known, the molecular mechanism leading to hemolytic anemia is still unclear and needs further investigation. Previous studies revealed an increased intracellular Ca2+ in red blood cells (RBCs) from patients with sickle cell disease, thalass...

journal_title：Frontiers in physiology

authors： Hertz L,Huisjes R,Llaudet-Planas E,Petkova-Kirova P,Makhro A,Danielczok JG,Egee S,Del Mar Mañú-Pereira M,van Wijk R,Vives Corrons JL,Bogdanova A,Kaestner L

更新日期：2017-09-06 00:00:00

abstract：:Studies of palate development are motivated by the all too common incidence of cleft palate, a birth defect that imposes a tremendous health burden and can leave lasting disfigurement. Although, mechanistic studies of palate growth and fusion have focused on growth factors such as Transforming Growth Factor ß-3 (Tgfß3...

journal_title：Frontiers in physiology

authors： Benson MD,Serrano MJ

更新日期：2012-09-26 00:00:00

abstract：:Previous studies report greater activation in the cortical motor network in controlling eccentric contraction (EC) than concentric contraction (CC) of human skeletal muscles despite lower activation level of the muscle associated with EC. It is unknown, however, whether the strength of functional coupling between the ...

journal_title：Frontiers in physiology

authors： Yao WX,Jiang Z,Li J,Jiang C,Franlin CG,Lancaster JL,Huang Y,Yue GH

更新日期：2016-11-15 00:00:00

abstract：INTRODUCTION:Severe dengue hemorrhagic fever (DHF) is a viral infection that acts to increase permeability of capillaries, resulting in internal hemorrhage. Linear frequency domain Fourier spectral analysis represents the most published noninvasive tool for diagnosing and assessing health status via calculated heart ra...

journal_title：Frontiers in physiology

authors： Carter R 3rd,Hinojosa-Laborde C,Convertino VA

更新日期：2014-02-25 00:00:00

abstract：:Before they develop competent endothermy, mammals and birds are sensitive to fluctuating temperature. It follows that early life thermal environment can trigger changes to the ontogeny of thermoregulatory control. At the ecological level, we have incomplete knowledge of how such responses affect temperature tolerance ...

journal_title：Frontiers in physiology

authors： Nord A,Giroud S

更新日期：2020-05-25 00:00:00

abstract：:The pre-occlusal eruption brings the molars into functional occlusion and initiates tensional strains during mastication. We hypothesized that upon establishment of occlusal contact, the periodontal ligament (PDL) undergoes cell and extracellular matrix maturation to adapt to this mechanical function. The PDL of 12 Wi...

journal_title：Frontiers in physiology

authors： Denes BJ,Ait-Lounis A,Wehrle-Haller B,Kiliaridis S

更新日期：2020-03-05 00:00:00

abstract：:The emergence of -omics technologies has allowed the collection of vast amounts of data on biological systems. Although, the pace of such collection has been exponential, the impact of these data remains small on many critical biomedical applications such as drug development. Limited resources, high costs, and low hit...

journal_title：Frontiers in physiology

authors： Kandoi G,Acencio ML,Lemke N

更新日期：2015-12-08 00:00:00

abstract：:Background: Pressure unloading induces the regression of left ventricular myocardial hypertrophy (LVH). Recent findings indicate that pharmacological activation of the soluble guanylate cyclase (sGC) - cyclic guanosine monophosphate (cGMP) pathway may also exert reverse-remodeling properties in the myocardium. Therefo...

journal_title：Frontiers in physiology

authors： Ruppert M,Korkmaz-Icöz S,Li S,Brlecic P,Németh BT,Oláh A,Horváth EM,Veres G,Pleger S,Grabe N,Merkely B,Karck M,Radovits T,Szabó G

更新日期：2019-01-08 00:00:00

abstract：:Ethylene is known to influence the cell cycle (CC) via poorly characterized roles whilst nitric oxide (NO) has well-established roles in the animal CC but analogous role(s) have not been reported for plants. As NO and ethylene signaling events often interact we examined their role in CC in cultured cells derived from ...

journal_title：Frontiers in physiology

authors： Novikova GV,Mur LA,Nosov AV,Fomenkov AA,Mironov KS,Mamaeva AS,Shilov ES,Rakitin VY,Hall MA

更新日期：2017-03-10 00:00:00

abstract：:Purpose: To determine if acute slow breathing at 6 breaths/min would improve baroreflex sensitivity (BRS) and heart rate variability (HRV), and lower blood pressure (BP) in adults after stroke. Methods: Twelve individuals completed two randomized study visits where they performed a 15-min bout of breathing exercises a...

journal_title：Frontiers in physiology

authors： Larson M,Chantigian DP,Asirvatham-Jeyaraj N,Van de Winckel A,Keller-Ross ML

更新日期：2020-10-30 00:00:00

abstract：:Circadian rhythms are essential for health and regulate various physiological functions. These rhythms are regulated by a negative-feedback loop involving clock genes in the suprachiasmatic nucleus (SCN) and peripheral tissues. The rate of secretion of salivary substances, ions, and water follows a circadian rhythm, h...

journal_title：Frontiers in physiology

authors： Satou R,Sato M,Kimura M,Ishizuka Y,Tazaki M,Sugihara N,Shibukawa Y

更新日期：2017-05-23 00:00:00

abstract：:We describe our development of the diffusion tensor imaging modality for the bovine ocular lens. Diffusion gradients were added to a spin-echo pulse sequence and the relevant parameters of the sequence were refined to achieve good diffusion weighting in the lens tissue, which demonstrated heterogeneous regions of diff...

journal_title：Frontiers in physiology

authors： Vaghefi E,Donaldson PJ

更新日期：2013-03-01 00:00:00

abstract：:Co-expressed genes often share similar functions, and gene co-expression networks have been widely used in studying the functionality of gene modules. Previous analysis indicated that genes are more likely to be co-expressed if they are either regulated by the same transcription factors, forming protein complexes or s...

journal_title：Frontiers in physiology

authors： Zhang C,Lee S,Mardinoglu A,Hua Q

更新日期：2016-05-02 00:00:00

abstract：:Finding an optimum for the cycling performance is not a trivial matter, since the literature shows the presence of many controversial aspects. In order to quantify different levels of performance, several indexes have been defined and used in many studies, reflecting variations in physiological and biomechanical facto...

journal_title：Frontiers in physiology

authors： Castronovo AM,Conforto S,Schmid M,Bibbo D,D'Alessio T

更新日期：2013-05-21 00:00:00

abstract：:The two forms of inorganic arsenic, arsenate (AsV) and arsenite (AsIII), are easily taken up by the cells of the plant root. Once in the cell, AsV can be readily converted to AsIII, the more toxic of the two forms. AsV and AsIII both disrupt plant metabolism, but through distinct mechanisms. AsV is a chemical analog o...

journal_title：Frontiers in physiology

authors： Finnegan PM,Chen W

更新日期：2012-06-06 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2019.00621.]. ...

journal_title：Frontiers in physiology

authors： Russo R,Marra R,Andolfo I,De Rosa G,Rosato BE,Manna F,Gambale A,Raia M,Unal S,Barella S,Iolascon A

更新日期：2020-08-11 00:00:00

abstract：:Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and behavior. Understanding the molecular mechanisms of preterm brain injuries is...

journal_title：Frontiers in physiology

authors： Pregnolato S,Chakkarapani E,Isles AR,Luyt K

更新日期：2019-04-24 00:00:00