Calcium-permeable ion channels in control of autophagy and cancer.

abstract：:Exercise and exogenous heat each stimulate multiple adaptations, but their roles are not well delineated, and that of the related stressor, dehydration, is largely unknown. While severe and prolonged hypohydration potentially "silences" the long-term heat acclimated phenotype, mild and transient dehydration may enhanc...

journal_title：Frontiers in physiology

authors： Akerman AP,Lucas SJE,Katare R,Cotter JD

更新日期：2017-10-09 00:00:00

abstract：:The effect of training status on post-exercise flow-mediated dilation (FMD) is not well characterized. We tested the hypothesis that the more trained the subjects, the lower the reduction in FMD after an acute bout of aerobic exercise. Forty-seven men (mean ± SD, age: 20.1 ± 1.2 years, body mass: 75.5 ± 5.1 kg, height...

journal_title：Frontiers in physiology

authors： Kapilevich LV,Kologrivova VV,Zakharova AN,Mourot L

更新日期：2020-05-08 00:00:00

abstract：:Advances in high-performance computing are enabling a new generation of software tools that employ computational modeling for surgical planning. Surgical management of laryngeal paralysis is one area where such computational tools could have a significant impact. The current paper describes a comprehensive effort to d...

journal_title：Frontiers in physiology

authors： Mittal R,Zheng X,Bhardwaj R,Seo JH,Xue Q,Bielamowicz S

更新日期：2011-05-02 00:00:00

abstract：:The aim of this study was to investigate the effects of two consecutive Crossfit® training sessions (24 h apart) designed to enhance work-capacity that involved both cardiovascular and muscular exercises on cytokines, muscle power, blood lactate and glucose. Nine male members of the CrossFit® community (age 26.7 ± 6.6...

journal_title：Frontiers in physiology

authors： Tibana RA,de Almeida LM,Frade de Sousa NM,Nascimento Dda C,Neto IV,de Almeida JA,de Souza VC,Lopes Mde F,Nobrega Ode T,Vieira DC,Navalta JW,Prestes J

更新日期：2016-06-28 00:00:00

abstract：:Background: Previous studies have observed significant heterogeneity in the magnitude of change in measures of metabolic response to exercise training. There are a lack of studies examining the prevalence of non-responders (NRs) in children while considering other potential environmental factors involved such as biolo...

journal_title：Frontiers in physiology

authors： Alvarez C,Ramírez-Campillo R,Ramírez-Vélez R,Izquierdo M

更新日期：2017-06-29 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) play important roles in transcriptional and post-transcriptional regulation. However, little is currently known about the mechanisms by which they regulate skeletal muscle development in the chicken. In this study, we used RNA sequencing to profile the leg muscle transcriptome (lncRNA an...

journal_title：Frontiers in physiology

authors： Li Z,Ouyang H,Zheng M,Cai B,Han P,Abdalla BA,Nie Q,Zhang X

更新日期：2017-01-09 00:00:00

abstract：:Data-driven computational neural network models have been used to study mechanisms for generating the motor patterns for breathing and breathing related behaviors such as coughing. These models have commonly been evaluated in open loop conditions or with feedback of lung volume simply represented as a filtered version...

journal_title：Frontiers in physiology

authors： O'Connor R,Segers LS,Morris KF,Nuding SC,Pitts T,Bolser DC,Davenport PW,Lindsey BG

更新日期：2012-07-23 00:00:00

abstract：:The ketogenic diet (KD) has been utilized as a dietary therapeutic for nearly a century. One experimental model particularly responsive to the KD is the BTBRT+tf/j (BTBR) mouse, which displays phenotypic characteristics of autism spectrum disorder (ASD) and insulin resistance. Recently, the study of impaired mitochond...

journal_title：Frontiers in physiology

authors： Newell C,Shutt TE,Ahn Y,Hittel DS,Khan A,Rho JM,Shearer J

更新日期：2016-12-27 00:00:00

abstract：:Mature spermatozoa have highly condensed DNA that is essentially silent both transcriptionally and translationally. Therefore, post translational modifications are very important for regulating sperm motility, morphology, and for male fertility in general. Protein sumoylation was recently demonstrated in human and rod...

journal_title：Frontiers in physiology

authors： Brohi RD,Wang L,Hassine NB,Cao J,Talpur HS,Wu D,Huang CJ,Rehman ZU,Bhattarai D,Huo LJ

更新日期：2017-06-13 00:00:00

abstract：:Hepatocellular carcinomas (HCCs) have different etiology and heterogenic genomic alterations lead to high complexity. The molecular features of HCC have largely been studied by gene expression and proteome profiling focusing on the correlations between the expression of specific markers and clinical data. Integration ...

journal_title：Frontiers in physiology

authors： D'Alessandro LA,Meyer R,Klingmüller U

更新日期：2013-02-25 00:00:00

abstract：:Pulmonary edema (PE) is an issue widely noted in acute exposure to hypoxia as seen in high altitude climbers, yet the etiology of this is not defined. Previous studies in rats showed that both hypoxia and strong sympathetic activation may induce PE. As acute exposure to hypoxia is accompanied by sympathetic activation...

journal_title：Frontiers in physiology

authors： Bölter C,Gabriel P,Appelt P,Salameh A,Schierle K,Rassler B

更新日期：2019-07-05 00:00:00

abstract：:Animal studies have shown that very early life events may have programing effects on adult metabolism and health. In this study, we aim, for the first, time to elucidate the effects of embryonic thermal manipulation (TM) on the performance of overfed mule ducks, in particular for the production of foie gras (fatty liv...

journal_title：Frontiers in physiology

authors： Massimino W,Davail S,Bernadet MD,Pioche T,Tavernier A,Ricaud K,Gontier K,Bonnefont C,Manse H,Morisson M,Fauconneau B,Collin A,Panserat S,Houssier M

更新日期：2019-12-12 00:00:00

abstract：:Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of the molecular changes in human or mouse paraspinal muscles exposed to microgravity. The aim of this study was to evaluate l...

journal_title：Frontiers in physiology

authors： Gambara G,Salanova M,Ciciliot S,Furlan S,Gutsmann M,Schiffl G,Ungethuem U,Volpe P,Gunga HC,Blottner D

更新日期：2017-05-05 00:00:00

abstract：:The olfactory system serves a vital role in the evolution and survival of insects, being involved in behaviors such as host seeking, foraging, mating, and oviposition. Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) are involved in the olfactory recognition process. In this study, BtabCSP11, a CSP11 g...

journal_title：Frontiers in physiology

authors： Zeng Y,Merchant A,Wu Q,Wang S,Kong L,Zhou X,Xie W,Zhang Y

更新日期：2020-06-30 00:00:00

abstract：PURPOSE:We investigated if oral ingestion of ibuprofen influenced leucocyte recruitment and infiltration following an acute bout of traditional resistance exercise Methods: Sixteen male subjects were divided into two groups that received the maximum over-the-counter dose of ibuprofen (1200mg d(-1)) or a similarly admin...

journal_title：Frontiers in physiology

authors： Vella L,Markworth JF,Paulsen G,Raastad T,Peake JM,Snow RJ,Cameron-Smith D,Russell AP

更新日期：2016-03-29 00:00:00

abstract：:Although interest in several areas of cephalopod research has emerged over the last decades (e.g., neurobiology, aquaculture, genetics, and welfare), especially following their 2010 inclusion in the EU Directive on the use of animals for experimental purposes, knowledge regarding the parasites of cephalopods is lackin...

journal_title：Frontiers in physiology

authors： Roumbedakis K,Drábková M,Tyml T,di Cristo C

更新日期：2018-11-20 00:00:00

abstract：:The year 2002 marked the tercentenary of Antonie van Leeuwenhoek's discovery of desiccation tolerance in animals. This remarkable phenomenon to sustain 'life' in the absence of water can be revived upon return of hydrating conditions. Today, coping with climate change-related factors, especially temperature-humidity i...

journal_title：Frontiers in physiology

authors： Thorat L,Nath BB

更新日期：2018-12-21 00:00:00

abstract：:Accurate evaluation of the appearance of QTc sex differences during childhood and adolescence is intricate. Inter-subject differences of individual QT/RR patterns make generic heart rate corrections inaccurate because of fast resting heart rates in children. The study investigated 527 healthy children and adolescents ...

journal_title：Frontiers in physiology

authors： Andršová I,Hnatkova K,Helánová K,Šišáková M,Novotný T,Kala P,Malik M

更新日期：2019-08-02 00:00:00

abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...

journal_title：Frontiers in physiology

authors： Chan PY,Cheng CH,Jhu YJ,Chen CL,von Leupoldt A

更新日期：2016-02-16 00:00:00

abstract：:Purpose: This study aimed to examine the exercise-mediated musculoskeletal recovery following hindlimb suspension (HS) in order to identify whether bone modeling and muscle hypertrophy would eventuate in a synchronized manner during recovery stage. Methods: To identify whether 2-week HS would be sufficient to induce a...

journal_title：Frontiers in physiology

authors： Song H,Cho S,Lee HY,Lee H,Song W

更新日期：2018-08-13 00:00:00

abstract：:Red blood cell nitric oxide synthase (RBC-NOS) dependent NO production positively affects RBC deformability which is known to improve oxygen supply to the working tissue. Whole-body electrostimulation (WB-EMS) has been shown to improve maximum strength, sprinting and jumping performance, and to increase deformability ...

journal_title：Frontiers in physiology

authors： Filipovic A,Bizjak D,Tomschi F,Bloch W,Grau M

更新日期：2019-05-09 00:00:00

abstract：:Defects in mitochondrial ribosomal proteins (MRPs) cause various diseases in humans. Because of the essential role of MRPs in synthesizing the essential subunits of oxidative phosphorylation (OXPHOS) complexes, identifying all of the protein components involved in the mitochondrial translational machinery is critical....

journal_title：Frontiers in physiology

authors： Koc EC,Cimen H,Kumcuoglu B,Abu N,Akpinar G,Haque ME,Spremulli LL,Koc H

更新日期：2013-07-30 00:00:00

abstract：:Basketball is a team sport, where fundamental skills - fundamentals - are key determinants for success. Jump-shot (JS) is a basketball fundamental used frequently during game. It is interesting to spread light on the relationship between effort intensity and JS ability. Study aim was to investigate different heart rat...

journal_title：Frontiers in physiology

authors： Padulo J,Nikolaidis PT,Cular D,Dello Iacono A,Vando S,Galasso M,Lo Storto D,Ardigò LP

更新日期：2018-08-03 00:00:00

abstract：:Sex determination/sex differentiation is determined by genetics, environmental factors, or the interactions of the two. The Transformer-2 (Tra-2) gene plays an important role in the sex determination cascade signal pathway in insects. In this study, the Tra-2 gene was isolated and characterized from the cDNA library o...

journal_title：Frontiers in physiology

authors： Cai L,Zheng J,Jia Y,Gu Z,Liu S,Chi M,Cheng S

更新日期：2020-07-09 00:00:00

abstract：:Collective behavior in the forest tent caterpillar (Malacosoma disstria) meets the thermal constraints of being an early spring folivore, but introduces other constraints in food choice. These are minimized by state-dependent, inter-individual, and ontogenetic variations in responses to social cues. Forest tent caterp...

journal_title：Frontiers in physiology

authors： Despland E

更新日期：2013-03-22 00:00:00

abstract：:Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19 inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation and disease processes like thrombosis, atherosclerosis, and lung injury. In endothelial cells, mitochondria regulate these inflammatory pathways ...

journal_title：Frontiers in physiology

authors： Chang R,Mamun A,Dominic A,Le NT

更新日期：2021-01-15 00:00:00

abstract：:Congenital haemolytic anaemias are inherited disorders caused by red blood cell membrane and cytoskeletal protein defects, deviant hemoglobin synthesis and metabolic enzyme deficiencies. In many cases, although the causing mutation might be known, the pathophysiology and the connection between the particular mutation ...

journal_title：Frontiers in physiology

authors： Petkova-Kirova P,Hertz L,Danielczok J,Huisjes R,Makhro A,Bogdanova A,Mañú-Pereira MDM,Vives Corrons JL,van Wijk R,Kaestner L

更新日期：2019-04-16 00:00:00

abstract：:Voltage gated potassium channels (KV) are membrane proteins that allow selective flow of K+ ions in a voltage-dependent manner. These channels play an important role in several excitable cells as neurons, cardiomyocytes, and vascular smooth muscle. Over the last 20 years, it has been shown that omega-3 polyunsaturated...

journal_title：Frontiers in physiology

authors： Moreno C,de la Cruz A,Valenzuela C

更新日期：2016-11-24 00:00:00

abstract：Background:Sickle cell disease (SCD) patients with asthma have an increased rate of vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) episodes when compared to those without asthma. We hypothesized that either asthma diagnosis or bronchodilator treatment might aggravate SCD via their modulating effect on the a...

journal_title：Frontiers in physiology

authors： Bokov P,El Jurdi H,Denjoy I,Peiffer C,Medjahdi N,Holvoet L,Benkerrou M,Delclaux C

更新日期：2020-02-26 00:00:00

abstract：:Overconsumption of fructose leads to metabolic syndrome as a result of hypertension, insulin resistance, and hyperlipidemia. In this study, the renal function of animals submitted to high fructose intake was analyzed from weaning to adulthood using in vivo and ex vivo methods, being compared with a normal control grou...

journal_title：Frontiers in physiology

authors： Yokota R,Ronchi FA,Fernandes FB,Jara ZP,Rosa RM,Leite APO,Fiorino P,Farah V,do Nascimento NRF,Fonteles MC,Casarini DE

更新日期：2018-10-10 00:00:00