α2-Adrenoreceptor Constraint of Catecholamine Release and Blood Pressure Is Enhanced in Female Spontaneously Hypertensive Rats.

abstract：:Autism is a devastating neurodevelopmental disorder with a polygenetic predisposition that seems to be triggered by multiple environmental factors during embryonic and/or early postnatal life. While significant advances have been made in identifying the neuronal structures and cells affected, a unifying theory that co...

journal_title：Frontiers in neuroscience

authors： Markram H,Rinaldi T,Markram K

更新日期：2007-10-15 00:00:00

abstract：:D-norpseudoephedrine (NPE), also known as cathine, is found naturally in the shrub Catha edulis "Khat." NPE has been widely used as an appetite suppressant for the treatment of obesity. Although it is known that NPE acts on α1-adrenergic receptors, there is little information about the role of dopamine receptors on NP...

journal_title：Frontiers in neuroscience

authors： Kalyanasundar B,Perez CI,Arroyo B,Moreno MG,Gutierrez R

更新日期：2020-10-16 00:00:00

abstract：:Evidence is mounting that LRRK2 function, particularly its kinase activity, is elevated in multiple forms of Parkinson's disease, both idiopathic as well as familial forms linked to mutations in the LRRK2 gene. However, sensitive quantitative markers of LRRK2 activation in clinical samples remain at the early stages o...

journal_title：Frontiers in neuroscience

authors： Rideout HJ,Chartier-Harlin MC,Fell MJ,Hirst WD,Huntwork-Rodriguez S,Leyns CEG,Mabrouk OS,Taymans JM

更新日期：2020-08-18 00:00:00

abstract：:Recently, Parkinson's disease-associated α-synuclein (αS) has emerged as an important regulator for SNARE-dependent vesicle fusion. However, it is controversial if excessive accumulation of αS, even in the absence of aggregation, impairs neurotransmission. Here we use a single vesicle fusion assay with ms time resolut...

journal_title：Frontiers in neuroscience

authors： Hawk BJD,Khounlo R,Shin YK

更新日期：2019-03-21 00:00:00

abstract：:The linearity and stationarity of fMRI time series need to be understood due to their important roles in the choice of approach for brain network analysis. In this paper, we investigated the stationarity and linearity of resting-state fMRI (rs-fMRI) time-series data from the Midnight Scan Club datasets. The degree of ...

journal_title：Frontiers in neuroscience

authors： Guan S,Jiang R,Bian H,Yuan J,Xu P,Meng C,Biswal B

更新日期：2020-06-11 00:00:00

abstract：:A P300 brain-computer interface (BCI) is a paradigm, where text characters are decoded from event-related potentials (ERPs). In a popular implementation, called P300 speller, a subject looks at a display where characters are flashing and selects one character by attending to it. The selection is recognized as the item...

journal_title：Frontiers in neuroscience

authors： Kirasirova L,Bulanov V,Ossadtchi A,Kolsanov A,Pyatin V,Lebedev M

更新日期：2020-12-03 00:00:00

abstract：:One of the most sought-after applications of neuroengineering is the communication between the arm and an artificial prosthetic device for the replacement of an amputated hand or the treatment of peripheral nerve injuries. For that, an electrode is placed around or inside the median nerve to serve as interface for rec...

journal_title：Frontiers in neuroscience

authors： Delgado-Martínez I,Badia J,Pascual-Font A,Rodríguez-Baeza A,Navarro X

更新日期：2016-07-01 00:00:00

abstract：:Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis, studies of candidate genes, Genome-Wide Association Studies (GWA...

journal_title：Frontiers in neuroscience

authors： Ciani M,Benussi L,Bonvicini C,Ghidoni R

更新日期：2019-05-16 00:00:00

abstract：:Olfaction is a sense involved in a complex set of tasks, influencing eating behavior, increasing awareness of environmental hazards and affecting social communication. Surprisingly, smell disorders are very frequent, especially in the elderly population. Several recent studies conducted mostly in older subjects have d...

journal_title：Frontiers in neuroscience

authors： Van Regemorter V,Hummel T,Rosenzweig F,Mouraux A,Rombaux P,Huart C

更新日期：2020-02-21 00:00:00

abstract：:Event-based sensing, i.e., the asynchronous detection of luminance changes, promises low-energy, high dynamic range, and sparse sensing. This stands in contrast to whole image frame-wise acquisition by standard cameras. Here, we systematically investigate the implications of event-based sensing in the context of visua...

journal_title：Frontiers in neuroscience

authors： Brosch T,Tschechne S,Neumann H

更新日期：2015-04-20 00:00:00

abstract：:Transcutaneous vagus nerve stimulation (tVNS) is widely used for clinical applications, but its mechanism of action is poorly understood. One candidate pathway that might mediate the effects of tVNS is an increase in GABAergic neurotransmission. In this study, we investigated the effect of tVNS on visual bistable perc...

journal_title：Frontiers in neuroscience

authors： Keute M,Boehrer L,Ruhnau P,Heinze HJ,Zaehle T

更新日期：2019-03-08 00:00:00

abstract：:Hardware-based spiking neural networks (SNNs) inspired by a biological nervous system are regarded as an innovative computing system with very low power consumption and massively parallel operation. To train SNNs with supervision, we propose an efficient on-chip training scheme approximating backpropagation algorithm ...

journal_title：Frontiers in neuroscience

authors： Kwon D,Lim S,Bae JH,Lee ST,Kim H,Seo YT,Oh S,Kim J,Yeom K,Park BG,Lee JH

更新日期：2020-07-07 00:00:00

abstract：Background:The mechanism of post-stroke cognitive impairment (PSCI) has not been explained. We aimed to investigate whether miR-let-7i participates in the PSCI and illuminates its underlying role in oxygen-glucose deprivation (OGD)-induced cell apoptosis. Methods:Blood samples from 36 subjects with PSCI and 38 with po...

journal_title：Frontiers in neuroscience

authors： Wang ZQ,Li K,Huang J,Huo TT,Lv PY

更新日期：2020-03-24 00:00:00

abstract：:Basic and neutral neurohypophyseal (NH) nonapeptides have evolved from vasotocin (VT) by a gene duplication at the base of the gnathostome lineage. In teleosts, VT and IT are the basic and neutral peptides, respectively. In the present study, VT and IT precursor genes of Heteropneustes fossilis and Clarias batrachus (...

journal_title：Frontiers in neuroscience

authors： Banerjee P,Chaube R,Joy KP

更新日期：2015-05-15 00:00:00

abstract：:In our complex acoustic environment, we are confronted with a mixture of sounds produced by several simultaneous sources. However, we rarely perceive these sounds as incomprehensible noise. Our brain uses perceptual organization processes to independently follow the emission of each sound source over time. If the acou...

journal_title：Frontiers in neuroscience

authors： Bidet-Caulet A,Bertrand O

更新日期：2009-09-15 00:00:00

abstract：:Rett syndrome (RTT) is a neurodevelopmental disease in children that is mainly caused by mutations in the MeCP2 gene, which codes for a transcriptional regulator. The expression of insulin-like growth factor-1 (IGF-1) is reduced in RTT patients and animal models, and IGF-1 treatment is a promising therapeutic strategy...

journal_title：Frontiers in neuroscience

authors： Yuan ZF,Mao SS,Shen J,Jiang LH,Xu L,Xu JL,Gao F

更新日期：2020-01-29 00:00:00

abstract：:Several studies of semantic memory in non-musical domains involving recognition of items from long-term memory have shown an age-related shift from the medial temporal lobe structures to the frontal lobe. However, the effects of aging on musical semantic memory remain unexamined. We compared activation associated with...

journal_title：Frontiers in neuroscience

authors： Sikka R,Cuddy LL,Johnsrude IS,Vanstone AD

更新日期：2015-10-06 00:00:00

abstract：:Our working model of the primate auditory cortex recognizes three major regions (core, belt, parabelt), subdivided into thirteen areas. The connections between areas are topographically ordered in a manner consistent with information flow along two major anatomical axes: core-belt-parabelt and caudal-rostral. Remarkab...

journal_title：Frontiers in neuroscience

authors： Hackett TA,de la Mothe LA,Camalier CR,Falchier A,Lakatos P,Kajikawa Y,Schroeder CE

更新日期：2014-04-22 00:00:00

abstract：:Auditory stream segregation refers to a segregated percept of signal streams with different acoustic features. Different approaches have been pursued in studies of stream segregation. In psychoacoustics, stream segregation has mostly been investigated with a subjective task asking the subjects to report their percept....

journal_title：Frontiers in neuroscience

authors： Dolležal LV,Brechmann A,Klump GM,Deike S

更新日期：2014-06-06 00:00:00

abstract：:Funding institutions and researchers increasingly expect that data will be shared to increase scientific integrity and provide other scientists with the opportunity to use the data with novel methods that may advance understanding in a particular field of study. In practice, sharing human subject data can be complicat...

journal_title：Frontiers in neuroscience

authors： Song X,Wang J,Wang A,Meng Q,Prescott C,Tsu L,Eckert MA

更新日期：2015-09-22 00:00:00

abstract：:Animal functional magnetic resonance imaging (fMRI) has provided key insights into the physiological mechanisms underlying healthy and diseased brain states. In non-human primates, resting-state fMRI studies are commonly conducted under isoflurane anesthesia, where anesthetic concentration is used to roughly infer ane...

journal_title：Frontiers in neuroscience

authors： Zhang Z,Cai DC,Wang Z,Zeljic K,Wang Z,Wang Y

更新日期：2019-04-11 00:00:00

abstract：:Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most prevalent diseases in the elderly population worldwide. A growing body of epidemiological studies suggest that people with T2DM are at a higher risk of developing AD. Likewise, AD brains are less capable of glucose uptake from the surroun...

journal_title：Frontiers in neuroscience

authors： Chatterjee S,Mudher A

更新日期：2018-06-08 00:00:00

abstract：:Progranulin (PGRN) is a tightly regulated, secreted glycoprotein involved in a wide range of biological processes that is of tremendous interest to the scientific community due to its involvement in neoplastic, neurodevelopmental, and neurodegenerative diseases. In particular, progranulin haploinsufficiency leads to f...

journal_title：Frontiers in neuroscience

authors： Gururaj S,Sampognaro PJ,Argouarch AR,Kao AW

更新日期：2020-12-14 00:00:00

abstract：:Precise diagnosis of psychiatric diseases and a comprehensive assessment of a patient's symptom severity are important in order to establish a successful treatment strategy for each patient. Although great efforts have been devoted to searching for diagnostic biomarkers of schizophrenia over the past several decades, ...

journal_title：Frontiers in neuroscience

authors： Kim DW,Lee SH,Shim M,Im CH

更新日期：2017-08-03 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis. Members of the CRF family of neuropeptides, including urocortin 1 (UCN 1), UCN 2, and UCN 3, bind to the G protein-coupled...

journal_title：Frontiers in neuroscience

authors： Fox JH,Lowry CA

更新日期：2013-09-20 00:00:00

abstract：:Using BOLD functional magnetic resonance imaging (fMRI) techniques, we examined the relationships between activities in the neural systems elicited by the decision stage of the Iowa Gambling Task (IGT), and food choices of either vegetables or snacks high in fat and sugar. Twenty-three healthy normal weight adolescent...

journal_title：Frontiers in neuroscience

authors： He Q,Xiao L,Xue G,Wong S,Ames SL,Xie B,Bechara A

更新日期：2014-11-04 00:00:00

abstract：:Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These processes develop in parallel with general improvement of self-regulatory abilities, and performan...

journal_title：Frontiers in neuroscience

authors： Eichele H,Eichele T,Marquardt L,Adolfsdottir S,Hugdahl K,Sørensen L,Plessen KJ

更新日期：2017-06-12 00:00:00

abstract：:The blood-brain barrier (BBB) mediates the communication between the periphery and the central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play a role in neurodegenerative disease. This has stimulated a wealth of information on the molecular impact of insulin in the brain, particularl...

journal_title：Frontiers in neuroscience

authors： Rhea EM,Banks WA

更新日期：2019-06-04 00:00:00

abstract：:Background: Physiological responses related to manual therapy (MT) treatment have been investigated over decades using various animal models. However, these studies have not been compiled and their collective findings appraised. The purpose of this scoping review was to assess current scientific knowledge on the physi...

journal_title：Frontiers in neuroscience

authors： Lima CR,Martins DF,Reed WR

更新日期：2020-05-08 00:00:00

abstract：:We introduce a novel recurrent neural network (RNN) approach to account for temporal dynamics and dependencies in brain networks observed via functional magnetic resonance imaging (fMRI). Our approach directly parameterizes temporal dynamics through recurrent connections, which can be used to formulate blind source se...

journal_title：Frontiers in neuroscience

authors： Hjelm RD,Damaraju E,Cho K,Laufs H,Plis SM,Calhoun VD

更新日期：2018-09-20 00:00:00