Insulin-Like Growth Factor-1 Down-Regulates the Phosphorylation of FXYD1 and Rescues Behavioral Deficits in a Mouse Model of Rett Syndrome.

abstract：:The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development, and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction, and other behaviors and it...

journal_title：Frontiers in neuroscience

authors： Beretta CA,Dross N,Guiterrez-Triana JA,Ryu S,Carl M

更新日期：2012-04-23 00:00:00

abstract：:Studies of delay discounting typically have involved choices between smaller, immediate outcomes and larger, delayed outcomes. In a study of delay discounting in humans, Green et al. (2005) added a period of time prior to both outcomes, creating a delay common to both. They found that the subjective value of the more ...

journal_title：Frontiers in neuroscience

authors： Calvert AL,Green L,Myerson J

更新日期：2011-08-17 00:00:00

abstract：:A new paradigm in neuroscience has recently emerged - the brain-gut axis (BGA). The contemporary focus in this paradigm has been gut → brain ("bottom-up"), in which the gut-microbiome, and its perturbations, affects one's psychological state-of-mind and behavior, and is pivotal in neurodegenerative disorders. The emer...

journal_title：Frontiers in neuroscience

authors： Isaiah S,Loots DT,Solomons R,van der Kuip M,Tutu Van Furth AM,Mason S

更新日期：2020-04-21 00:00:00

abstract：:The Artificial Intelligence (AI) revolution foretold of during the 1960s is well underway in the second decade of the twenty first century. Its period of phenomenal growth likely lies ahead. AI-operated machines and technologies will extend the reach of Homo sapiens far beyond the biological constraints imposed by evo...

journal_title：Frontiers in neuroscience

authors： Krichmar JL,Severa W,Khan MS,Olds JL

更新日期：2019-06-27 00:00:00

abstract：:Intracranial chemical injection (ICI) methods have been used to identify the locations in the brain where feeding behavior can be controlled acutely. Scientists conducting ICI studies often document their injection site locations, thereby leaving kernels of valuable location data for others to use to further character...

journal_title：Frontiers in neuroscience

authors： Khan AM

更新日期：2013-12-18 00:00:00

abstract：:Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is believed to play a role in listening in noise and protection from a...

journal_title：Frontiers in neuroscience

authors： Smith SB,Lichtenhan JT,Cone BK

更新日期：2017-04-04 00:00:00

abstract：:Spinocerebellar ataxia (SCA) is a part of the cerebellar neurodegenerative disease group that is diverse in genetics and phenotypes. It usually shows autosomal dominant inheritance. SCAs, always together with the cerebellar degeneration, may exhibit clinical deficits in brainstem or eye, especially retina or optic ner...

journal_title：Frontiers in neuroscience

authors： Park JY,Joo K,Woo SJ

更新日期：2020-08-21 00:00:00

abstract：:To ensure survival, animals must update the internal representations of their environment in a trial-and-error fashion. Psychological studies of associative learning and neurophysiological analyses of dopaminergic neurons have suggested that this updating process involves the temporal-difference (TD) method in the bas...

journal_title：Frontiers in neuroscience

authors： Wen C,Ogura Y,Matsushima T

更新日期：2016-11-08 00:00:00

abstract：:The melanocortin receptors (MCRs) are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the MCRs are only found in chordates. The presence of five genes in the family (i.e., mc1r, mc2r, mc3r, mc4r, mc5r) in representatives of...

journal_title：Frontiers in neuroscience

authors： Dores RM

更新日期：2013-04-10 00:00:00

abstract：:To function effectively, brains need to make predictions about their environment based on past experience, i.e., they need to learn about their environment. The algorithms by which learning occurs are of interest to neuroscientists, both in their own right (because they exist in the brain) and as a tool to model parti...

journal_title：Frontiers in neuroscience

authors： O'Reilly JX

更新日期：2013-06-14 00:00:00

abstract：:The visual system is organized in a parallel and hierarchical architecture. However, the plasticity in hierarchical neural networks is controversial across different response features and at different levels. In this study, we recorded areas 17 and 21a, earlier and intermediate stages of the visual cortex in the cat, ...

journal_title：Frontiers in neuroscience

authors： Wang J,Ni Z,Jin A,Yu T,Yu H

更新日期：2019-10-11 00:00:00

abstract：:[This corrects the article on p. 560 in vol. 10, PMID: 28008304.]. ...

journal_title：Frontiers in neuroscience

authors： Muñoz-Moreno E,Fischi-Gomez E,Batalle D,Borradori-Tolsa C,Eixarch E,Thiran JP,Gratacós E,Hüppi PS

更新日期：2017-05-09 00:00:00

abstract：:While adult neurogenesis is considered to be restricted to the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ), recent studies in humans and rodents provide evidence for newly generated neurons in regions generally considered as non-neurogenic, e.g., the striatum. Stimulating dopaminergic neurotransmi...

journal_title：Frontiers in neuroscience

authors： Salvi R,Steigleder T,Schlachetzki JC,Waldmann E,Schwab S,Winner B,Winkler J,Kohl Z

更新日期：2016-03-11 00:00:00

abstract：:Alcoholism is a serious public health concern that is characterized by the development of tolerance to alcohol's effects, increased consumption, loss of control over drinking and the development of physical dependence. This cycle is often times punctuated by periods of abstinence, craving and relapse. The development ...

journal_title：Frontiers in neuroscience

authors： Rao PS,Bell RL,Engleman EA,Sari Y

更新日期：2015-04-23 00:00:00

abstract：:Roughly one-third of the human lifetime is spent in sleep, yet the reason for sleep remains unclear. Understanding the physiologic function of sleep is crucial toward establishing optimal health. Several proposed concepts address different aspects of sleep physiology, including humoral and circuit-based theories of sl...

journal_title：Frontiers in neuroscience

authors： Lazarus M,Oishi Y,Bjorness TE,Greene RW

更新日期：2019-07-17 00:00:00

abstract：:It is known that olfaction is essential for the occurrence of sexual behavior in male goldfish. Sex pheromones from ovulatory females elicit male sexual behavior, chasing, and sperm releasing act. In female goldfish, ovarian prostaglandin F2α (PGF) elicits female sexual behavior, egg releasing act. It has been conside...

journal_title：Frontiers in neuroscience

authors： Kawaguchi Y,Nagaoka A,Kitami A,Mitsuhashi T,Hayakawa Y,Kobayashi M

更新日期：2014-04-30 00:00:00

abstract：:Abnormal accumulation of TAR DNA-binding protein 43 (TDP-43) in the cytoplasm and its disappearance from the nucleus are pathological features of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) and are directly involved in the pathogenesis of these conditions. TDP-43 is an essential nuclear protein...

journal_title：Frontiers in neuroscience

authors： Sugai A,Kato T,Koyama A,Koike Y,Kasahara S,Konno T,Ishihara T,Onodera O

更新日期：2018-02-01 00:00:00

abstract：:Value-based decision making relies on distributed neural systems that weigh the benefits of actions against the cost required to obtain a given outcome. Perturbations of these systems are thought to underlie abnormalities in action selection seen across many neuropsychiatric disorders. Genetic tools in mice provide a ...

journal_title：Frontiers in neuroscience

authors： Alabi OO,Fortunato MP,Fuccillo MV

更新日期：2019-02-07 00:00:00

abstract：:This paper developed a cognitive task-load (CTL) classification algorithm and allocation strategy to sustain the optimal operator CTL levels over time in safety-critical human-machine integrated systems. An adaptive human-machine system is designed based on a non-linear dynamic CTL classifier, which maps a set of elec...

journal_title：Frontiers in neuroscience

authors： Zhang J,Yin Z,Wang R

更新日期：2017-03-17 00:00:00

abstract：:The menstrual cycle has attracted research interest ever since the 1930s. For many researchers the menstrual cycle is an excellent model of ovarian steroid influence on emotion, behavior, and cognition. Over the past years methodological improvements in menstrual cycle studies have been noted, and this review summariz...

journal_title：Frontiers in neuroscience

authors： Sundström Poromaa I,Gingnell M

更新日期：2014-11-24 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by T helper (h)1 and/or Th17 CD4 T cells that drive inflammatory lesion development along with demyelination and neuronal damage. Defects in immune regulatory mechanisms are thought to play a role in the pathogenesis of MS. W...

journal_title：Frontiers in neuroscience

authors： Miller NM,Wang J,Tan Y,Dittel BN

更新日期：2015-08-18 00:00:00

abstract：:Neurogenesis, the process of generating new neurons in the brain, fascinates researchers for its promise to affect multiple cognitive and functional processes in both health and disease. Many cellular pathways are involved in the regulation of neurogenesis, a complexity exemplified by the extensive regulation of this ...

journal_title：Frontiers in neuroscience

authors： Barak B,Feldman N,Okun E

更新日期：2014-08-28 00:00:00

abstract：Introduction:Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and v...

journal_title：Frontiers in neuroscience

authors： Sousa DC,Leal I,Moreira S,do Vale S,Silva-Herdade AS,Aguiar P,Dionísio P,Abegão Pinto L,Castanho MARB,Marques-Neves C

更新日期：2019-06-12 00:00:00

abstract：:The aim of this study was to explore changes in intracellular ATP generation and tight junction protein expression during the course of brain edema induced by subacute poisoning of 1,2-dichloroethane (1,2-DCE). Mice were exposed to 1.2 g/m3 1,2-DCE for 3.5 h per day for 1, 2, or 3 days, namely group A, B, and C. Na+-K...

journal_title：Frontiers in neuroscience

authors： Wang G,Yuan Y,Gao L,Tan X,Yang G,Zhao F,Jin Y

更新日期：2018-01-23 00:00:00

abstract：:Newborn neurons are continuously added to the hippocampal dentate gyrus throughout adulthood. In this review, we analyze the maturational stages that newborn granule neurons go through, with a focus on their unique morphological features during each stage under both physiological and pathological circumstances. In add...

journal_title：Frontiers in neuroscience

authors： Llorens-Martín M,Rábano A,Ávila J

更新日期：2016-01-19 00:00:00

abstract：:Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer's disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The APP family encompasse...

journal_title：Frontiers in neuroscience

authors： Lazarov O,Demars MP

更新日期：2012-06-04 00:00:00

abstract：:Neural oscillations in the alpha band (7-13 Hz) are commonly associated with disengagement of visual attention. However, recent studies have also associated alpha with processes of attentional control and stability. We addressed this issue in previous experiments by delivering transcranial alternating current stimulat...

journal_title：Frontiers in neuroscience

authors： Clayton MS,Yeung N,Cohen Kadosh R

更新日期：2018-02-13 00:00:00

abstract：:There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, meaning a subgroup of tinnitus patients responsive to specific treatments. Tinnitus patients wi...

journal_title：Frontiers in neuroscience

authors： Edvall NK,Gunan E,Genitsaridi E,Lazar A,Mehraei G,Billing M,Tullberg M,Bulla J,Whitton J,Canlon B,Hall DA,Cederroth CR

更新日期：2019-08-22 00:00:00

abstract：:Head motion is one of major concerns in current resting-state functional MRI studies. Image realignment including motion estimation and spatial resampling is often applied to achieve rigid-body motion correction. While the accurate estimation of motion parameters has been addressed in most studies, spatial resampling ...

journal_title：Frontiers in neuroscience

authors： Yuan L,He H,Zhang H,Zhong J

更新日期：2016-12-27 00:00:00

abstract：:The goal of our research was to develop a compound computational model that predicts the "opposite" effects of the alternating aftereffects stimuli, such as the "color dove illusion" (Barkan and Spitzer, 2017), and the "filling in the afterimage after the image" (van Lier et al., 2009). The model is based on a filling...

journal_title：Frontiers in neuroscience

authors： Cohen-Duwek H,Spitzer H

更新日期：2018-08-17 00:00:00