Abstract:
:Obesity and diabetes is a co-pandemic and a major health concern that is expanding. It has many psychosocial and economic consequences due to morbidity and mortality of this disease combination. The pathophysiology of obesity and related diabetes is complex and multifactorial. One arm of this disease process is the genetic susceptibility. Other arm is dependent on the intricate neuro-humoral factors that converge in the central nerve system. Gut hormones and the adipose tissue derived factors plays an important role in this delicate network. Bariatric surgery provides the only durable option for treatment of obesity and furthermore it provides a remission in the concomitant diseases that accompany obesity. This review provides a brief insight to all these mechanisms and tries to deduce the possible reasons of remission of type 2 diabetes after bariatric surgery.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Cetinkunar S,Erdem H,Aktimur R,Sozen Sdoi
10.12998/wjcc.v3.i6.504subject
Has Abstractpub_date
2015-06-16 00:00:00pages
504-9issue
6issn
2307-8960journal_volume
3pub_type
杂志文章,评审abstract:BACKGROUND:Surgical treatment for large carotid body tumor (CBT), particularly the Shamblin III type, is challenging and rarely reported. CASE SUMMARY:In July 2014, a 63-year-old woman presented to our hospital with a large CBT (130 mm × 60 mm × 70 mm). The lesion was hypervascular, spanned from the first to the seven...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i16.2346
更新日期:2019-08-26 00:00:00
abstract::Isolated neurofibromas that affect the gastrointestinal tract are rare and almost always manifest as neurofibromatosis type 1 or multiple endocrine neoplasia type 2b. In this paper, we present a case of a 24-year-old female with abdominal pain who discharged a neurofibroma in her stool without any blood on it. A colon...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i11.455
更新日期:2018-10-06 00:00:00
abstract:BACKGROUND:The global pandemic of coronavirus disease 2019 pneumonia poses a particular challenge to the emergency surgical treatment of elderly patients with high-risk acute abdominal diseases. Elderly patients are a high-risk group for surgical treatment. If the incarceration of gallstones cannot be relieved, emergen...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i20.4908
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Neurofibromatosis is an autosomal dominant genetic disorder with various manifestations. Systemic multiple neurofibromatosis is rare in infancy. The disease is difficult to identify in the early stage, and it is prone to misdiagnosis and missed diagnosis. In the presence of lower limb swelling with subcutane...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5678
更新日期:2020-11-26 00:00:00
abstract::We describe clinical, diagnostic features and follow up of a patient with a vanishing brain lesion. A 14-year-old child admitted to the department of Neurology at September 2009 with a history of subacute onset of fever, anorexia, vomiting, blurring of vision and right hemiparesis since one month. Magnetic resonance i...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i11.956
更新日期:2015-11-16 00:00:00
abstract:BACKGROUND:Transanal minimally invasive surgery (TAMIS) is a good choice for resection of rectal neoplasms. Endoscopic mucosal resection (EMR) is also widely used in the treatment of benign rectal tumors such as rectal polyps and rectal adenomas. However, no studies have compared the outcome of TAMIS and EMR. AIM:To c...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i19.4311
更新日期:2020-10-06 00:00:00
abstract:AIM:To investigate the safety and efficacy of S-1 plus oxaliplatin (SOX) as an adjuvant chemotherapy regimen in gastric cancer (GC) after D2 dissection. METHODS:GC Patients who underwent D2 gastrectomy from September 2009 to December 2011 in four Chinese institutions were enrolled. Patients with stage IB-IIIC GC, who ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v6.i10.373
更新日期:2018-09-26 00:00:00
abstract:BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-yea...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i24.6524
更新日期:2020-12-26 00:00:00
abstract::Posterior reversible encephalopathy syndrome (PRES) is a clinico-ragiological syndrome presenting with neurological symptoms and characteristic radiologic findings. PRES occurs in the setting of various clinical conditions and requires prompt management of the causative factor for a full recovery. This is a case repor...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v4.i4.103
更新日期:2016-04-16 00:00:00
abstract:BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered coronavirus that has generated a worldwide outbreak of infections. Many people with coronavirus disease-2019 (COVID-19) have developed severe illness, and a significant number have died. However, little is known regarding infe...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i23.6016
更新日期:2020-12-06 00:00:00
abstract::In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastas...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i11.2111
更新日期:2020-06-06 00:00:00
abstract:AIM:To investigated the association between the tumor cells' expression of E-cadherin and the numbers of several types of inflammatory cells infiltrating into the invasive portion of gallbladder cancer (GBC). METHODS:We analyzed 50 GBC cases for which a sufficient amount of tumor tissues for tissue microarray (TMA) ha...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v5.i1.1
更新日期:2017-01-16 00:00:00
abstract:BACKGROUND:Extrahepatic metastasis (EHM) from hepatocellular carcinoma (HCC) occurs in 10%-15% of cases following initial treatment. The most frequent sites of EHM are the lung, lymph nodes, and bone. Gastrointestinal or brain metastasis from HCC is rarely reported. Here, we report a rare case of concurrent HCC metasta...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i16.3534
更新日期:2020-08-26 00:00:00
abstract:BACKGROUND:Sebaceous lymphadenoma is a benign tumor that occurs rarely in the salivary glands, most commonly in the parotid glands or periparotid lymph nodes, and even more rarely undergoes malignant transformation into a sebaceous lymphadenocarcinoma. CASE SUMMARY:We report an 82-year-old woman who presented with a p...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5751
更新日期:2020-11-26 00:00:00
abstract::Dysbetalipoproteinemia is a rare familial dyslipidemia characterized by approximately equally elevated serum cholesterol and triglyceride levels due to accumulated remnant lipoproteins in apolipoprotein E2/E2 homozygotes. It is associated with an increased risk for premature cardiovascular disease. Thus, making a diag...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i4.371
更新日期:2015-04-16 00:00:00
abstract:BACKGROUND:Congenital bronchobiliary fistula is a rare developmental abnormality with an abnormal fistula between the respiratory system and biliary tract. The aim of this report is to analyze and summarize the clinical features and experience of diagnosing and treating congenital bronchobiliary fistula (CBBF) occurrin...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i7.881
更新日期:2019-04-06 00:00:00
abstract::Biliary tract cancer, or cholangiocarcinoma, comprises a heterogeneous group of malignant tumors that can emerge at any part of the biliary tree. This group is the second most common type of primary liver cancer. Diagnosis is usually based on symptoms, which may be heterogeneous, and nonspecific biomarkers in serum an...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v7.i14.1732
更新日期:2019-07-26 00:00:00
abstract:BACKGROUND:Thrombotic thrombocytopenic purpura (TTP), a subtype of thrombotic microangiopathy, has a very high fatality rate if there is no timely diagnosis or treatment. Here, we report a case of TTP refractory to high displacement plasma exchange, which was later successfully treated with rituximab. CASE SUMMARY:Her...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i12.2617
更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:Apatinib is a small-molecule multitargeted tyrosine kinase inhibitor. Apatinib has demonstrated encouraging antitumor activities. This study aimed to observe the efficacy and safety of apatinib for the treatment of multiple brain micrometastases. CASE SUMMARY:We report two patients with multiple brain micro...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i7.1326
更新日期:2020-04-06 00:00:00
abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i19.4652
更新日期:2020-10-06 00:00:00
abstract::It is well-known that colonoscopy is considered the gold standard for colon cancer prevention. Although performed by experienced endoscopists, the matter remains of polyps missed during this examination. The reasons may include the size, shape and location of the lesions. Many colorectal cancer screening programs have...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v5.i7.258
更新日期:2017-07-16 00:00:00
abstract:BACKGROUND:Hemorrhoidal prolapse is a common benign disease with a high incidence. The treatment procedure for prolapse and hemorrhoids (PPH) remains an operative method used for internal hemorrhoid prolapse. Although it is related to less pos-operative pain, faster recovery and shorter hospital stays, the postoperativ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v9.i1.36
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Lymphoepithelioma-like carcinoma (LELC) is a non-keratinizing carcinoma with rich lymphocytic infiltration, which primarily originates from the nasopharynx. Primary lung LELC is a type of lung cancer with a relatively low incidence. Herein, we report a rare case of lung LELC with expression of CD56. We also ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i7.1257
更新日期:2020-04-06 00:00:00
abstract::Primary mediastinal neuroendocrine tumors are a rare malignancy that accounts for < 10% of all mediastinal tumors. The case presented here involves a 52-year-old man who had been suffering for 3 mo from chronic cough, anorexia and substantial weight loss, as well as 2 wk of jaundice prior to his admission. A computed ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i10.915
更新日期:2015-10-16 00:00:00
abstract::Probiotics are known as "live microorganisms" and have been proven to have a health effect on hosts at the proper dose. Recently, a kind of probiotic mixture including eight live bacterial strains, VSL#3, has attracted considerable attention for its combined effect. VSL#3 is the only probiotic considered as a kind of ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i8.1361
更新日期:2020-04-26 00:00:00
abstract:AIM:To investigate whether the change in pre-/post-operation serum alpha-fetoprotein (AFP) levels is a predictive factor for hepatocellular carcinoma (HCC) outcomes. METHODS:We retrospectively analyzed 334 HCC patients who underwent hepatic resection at our hospital between January 2006 and December 2016. The patients...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v6.i6.110
更新日期:2018-06-16 00:00:00
abstract:BACKGROUND:Pancreatic cancer has a poor prognosis; 40%-50% of patients have liver metastases at the time of initial diagnosis and only 15%-20% undergo surgical resection. Irreversible electroporation (IRE) is a new, non-thermal local ablation method for solid tumors, which can induce cell membrane permeabilization, res...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i2.390
更新日期:2020-01-26 00:00:00
abstract:BACKGROUND:Giant paraesophageal hiatal hernias (HH) are very infrequent, and their spectrum of clinical manifestations is large. Giant HH mainly occurs in elderly patients, and its relationship with anemia has been reported. For the surgical treatment of large HH, Nissen fundoplication is the most common antireflux pro...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i6.1180
更新日期:2020-03-26 00:00:00
abstract:BACKGROUND:The incidence of pancreatic neuroendocrine tumors (PNETs) is now increasing rapidly. The tumor grade of PNETs significantly affects the treatment strategy and prognosis. However, there is still no effective way to non-invasively classify PNET grades. Machine learning (ML) algorithms have shown potential in i...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i13.1611
更新日期:2019-07-06 00:00:00
abstract::Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Despite significant advances in therapy over the last decade CLL remains incurable. Current front-line therapy often consists of chemoimmunotherapy-based regimens, most commonly the fludarabine, cyclophosphamide plus rituximab combina...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i8.694
更新日期:2015-08-16 00:00:00