Abstract:
:In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastasize to the injured liver, which included hepatitis or cirrhotic liver. The benefits of antiviral therapy on hepatocellular carcinoma have also been identified. This review discusses the role of antiviral therapy on the liver. Antiviral therapy may reduce potential liver metastasis associated with CRC in several mechanistic aspects.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Wang Q,Yu CRdoi
10.12998/wjcc.v8.i11.2111subject
Has Abstractpub_date
2020-06-06 00:00:00pages
2111-2115issue
11issn
2307-8960journal_volume
8pub_type
杂志文章,评审abstract:BACKGROUND:Myocardial bridge (MB) will compress the mural coronary artery (MCA) during the systole and cause myocardial ischemia. In the diagnosis of coronary heart disease (CHD), because the structure of MB is difficult to be observed by coronary angiography (CAG), the clinical study of the influence of MB on CHD is l...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i15.1986
更新日期:2019-08-06 00:00:00
abstract::We report the case of an urgent nephrectomy because of a pyonephrosis and sepsis due to an unsuspected sarcomatoid transitional cell carcinoma, an infrequent subtype with a bad oncological prognosis. We present a 58-year-old man assessed by internal medicine for a general syndrome and weakness many months previously. ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i6.215
更新日期:2014-06-16 00:00:00
abstract::Crohn's disease (CD) can involve any part of the gastrointestinal tract from the mouth to anus. However, gastroduodenal CD is rare with a frequency reported to range between 0.5% and 4.0%. Most patients with gastroduodenal CD have concomitant lesions in the terminal ileum or colon, but isolated gastroduodenal Crohn's ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v4.i6.146
更新日期:2016-06-16 00:00:00
abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i19.4652
更新日期:2020-10-06 00:00:00
abstract::Biliary tract cancer, or cholangiocarcinoma, comprises a heterogeneous group of malignant tumors that can emerge at any part of the biliary tree. This group is the second most common type of primary liver cancer. Diagnosis is usually based on symptoms, which may be heterogeneous, and nonspecific biomarkers in serum an...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v7.i14.1732
更新日期:2019-07-26 00:00:00
abstract:BACKGROUND:Coronary artery spasm is a major cause of myocardial ischemia. Although coronary artery spasm has been known for a long time, its mechanism has not yet been identified. Many clinicians, especially young clinicians pay less attention to coronary artery spasm, which may lead to some patients not being appropri...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i16.3601
更新日期:2020-08-26 00:00:00
abstract::Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate tha...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i7.575
更新日期:2015-07-16 00:00:00
abstract:BACKGROUND:Medical robot is a promising surgical tool, but no specific one has been designed for interventional treatment of chronic pain. We developed a computed tomography-image based navigation robot using a new registration method with binocular vision. This kind of robot is appropriate for minimal invasive interve...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i16.3440
更新日期:2020-08-26 00:00:00
abstract:BACKGROUND:Surgical treatment for large carotid body tumor (CBT), particularly the Shamblin III type, is challenging and rarely reported. CASE SUMMARY:In July 2014, a 63-year-old woman presented to our hospital with a large CBT (130 mm × 60 mm × 70 mm). The lesion was hypervascular, spanned from the first to the seven...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i16.2346
更新日期:2019-08-26 00:00:00
abstract:BACKGROUND:In rare cases, odontogenic keratocysts (ODs) transform into squamous cell carcinoma. Intervals between the first attendance of a patient and the diagnosis of OD with malignant transformation vary from weeks to years. In this article, we report a case of malignancy derived from OD with a five-day delay in dia...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i11.2374
更新日期:2020-06-06 00:00:00
abstract:BACKGROUND:This study aimed to identify factors associated with antibiotic-associated diarrhea (AAD) in patients in the department of intensive care medicine who received antibiotic monotherapy in order to reduce the incidence of AAD and improve rational use of antibiotics in these patients. AIM:To report the incidenc...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i10.1908
更新日期:2020-05-26 00:00:00
abstract::Although Kaposi sarcoma (KS) has been more traditionally considered an AIDS-defining illness, it may also be seen in individuals on immunosuppresive therapy. We report a case of a patient who presented to the hospital in the setting of increasingly refractory ulcerative colitis. Computed tomography scan of the abdomen...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v5.i12.423
更新日期:2017-12-16 00:00:00
abstract:BACKGROUND:Hypoglycemia due to non-insulin-producing tumors is referred to as non-islet cell tumor hypoglycemia (NICTH). As NICTH is a rare lesion, the natural course of NICTH is not well understood. We report a case of NICTH that was observed 30 years before the onset of hypoglycemia. CASE SUMMARY:A 50-year-old man w...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v9.i1.163
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:We analyzed the main features of an infant diagnosed with temporary neonatal cyanosis in order to strengthen our understanding of the disease. CASE SUMMARY:We report a patient diagnosed with temporary neonatal cyanosis. The main clinical characteristics, gene mutation and treatment are discussed and a revie...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i1.217
更新日期:2020-01-06 00:00:00
abstract:BACKGROUND:Since the beginning of the pandemic, coronavirus disease-2019 (COVID-19) in children has shown milder cases and a better prognosis than adults. Although the respiratory tract is the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cardiovascular involvement is emerging as one ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i21.5250
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:Systemic amyloidosis in which multiple systems can be involved has become a common clinical disease. When the liver is affected, symptoms such as abdominal distension, fatigue, edema, liver, and jaundice could appear. To date, hepatic amyloidosis combined with hepatic venular occlusive disease and Budd-Chiar...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i20.3282
更新日期:2019-10-26 00:00:00
abstract::Gastrointestinal (GI) cancer is one of the leading causes of cancer-related deaths worldwide. According to the Global Cancer Statistics, colorectal cancer is the second leading cause of cancer-related mortality, closely followed by gastric cancer (GC). Environmental, dietary, and lifestyle factors including cigarette ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i12.2425
更新日期:2020-06-26 00:00:00
abstract::Colovesical fistulas (CVFs) are rare complications of very advanced cancers of the abdominal or pelvic cavity and often cause diagnostic troubles. CVFs are found more often in males, whereas females usually suffer from rectovaginal or vesicovaginal fistulas. This article presents a case of a female patient who was adm...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i12.538
更新日期:2018-10-26 00:00:00
abstract:BACKGROUND:Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor that is characterized by spindle cells differentiated from muscle fibroblasts and infiltration of various types of inflammatory cells. IMT can occur at any age and at any anatomic site. The most common location of IMT is the bladder in the ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i24.4366
更新日期:2019-12-26 00:00:00
abstract:BACKGROUND:Scapular fracture has a low incidence rate, accounting for 0.4%-0.9% of all fractures, and scapular neck fractures are extremely rare, comprising approximately 7%-25% of all scapular fractures. Scapular neck fractures are often studied as case reports mostly accompanied by other injuries, thus leading to con...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i24.6450
更新日期:2020-12-26 00:00:00
abstract::Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The most common clinical presentation is an unilateral, discrete breast mass, nipple retraction and even a sinus formation often associated with an inflammation of the ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v2.i12.852
更新日期:2014-12-16 00:00:00
abstract::Inflammation is a central process in several disorders and contributes to cancer progression. Inflammation involves a complex cascade of pro-inflammatory and anti-inflammatory signaling events with protein and lipid mediators. Recent advances in lipid detection have revealed the importance of lipid mediators in inflam...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v4.i7.155
更新日期:2016-07-16 00:00:00
abstract::Probiotics are known as "live microorganisms" and have been proven to have a health effect on hosts at the proper dose. Recently, a kind of probiotic mixture including eight live bacterial strains, VSL#3, has attracted considerable attention for its combined effect. VSL#3 is the only probiotic considered as a kind of ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i8.1361
更新日期:2020-04-26 00:00:00
abstract::Relapsing polychondritis (RP) is a rare autoimmune disease with chronic inflammatory/destructive lesions of the cartilaginous tissues. In one third of the cases it is associated with other autoimmune disorders, mostly with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). We report three cases o...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i12.912
更新日期:2014-12-16 00:00:00
abstract::Identification of left ventricular mural thrombus (LVT) may be challenging depending on the imaging modality used. We present a case of LVT which was incidentally identified on cine cardiac magnetic resonance imaging (CMR). A sixty-four years old female presented with worsening dyspnea on exertion with troponin elevat...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i6.127
更新日期:2018-06-16 00:00:00
abstract:BACKGROUND:Immunoglobulin A nephropathy (IgAN) is the most commonly encountered glomerular disease in Asian countries. It has a broad clinical presentation, and it is frequently associated with other conditions. Chronic liver disease is well recognized as the leading cause of secondary IgAN. However, cases of IgAN asso...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i17.3828
更新日期:2020-09-06 00:00:00
abstract:BACKGROUND:Type A insulin resistance syndrome is a rare disorder caused by mutations in the gene encoding the insulin receptor. Its coexistence with ovarian serous papillary cystadenofibroma is even rarer. CASE SUMMARY:A 14-year-old girl developed type A insulin resistance syndrome and showed high fasting insulin, glu...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i15.3334
更新日期:2020-08-06 00:00:00
abstract:BACKGROUND:Paragonimiasis is a food-borne parasitic infection caused by lung flukes of the genus Paragonimus. Although the most common site of infection is the pleuropulmonary area, the parasite can also reach other parts of the body on its journey from the intestines to the lungs, ending up in locations such as the br...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i24.4292
更新日期:2019-12-26 00:00:00
abstract:BACKGROUND:Pulmonary benign metastatic leiomyoma (PBML), which is very rare, is a type of benign metastatic leiomyoma (BML). Here, we report a case of PBML, finally diagnosed through multidisciplinary team (MDT) discussions, and provide a literature review of the disease. CASE SUMMARY:A 55-year old asymptomatic woman ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i14.3082
更新日期:2020-07-26 00:00:00
abstract:BACKGROUND:Invasive fungal rhinosinusitis (IFR) caused by Cunninghamella is very rare but has an extremely high fatality rate. There have been only seven cases of IFR caused by Cunninghamella reported in English and, of these, only three patients survived. In this article, we present another case of IFR caused by Cunni...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i2.228
更新日期:2019-01-26 00:00:00