Abstract:
BACKGROUND:Immunoglobulin A nephropathy (IgAN) is the most commonly encountered glomerular disease in Asian countries. It has a broad clinical presentation, and it is frequently associated with other conditions. Chronic liver disease is well recognized as the leading cause of secondary IgAN. However, cases of IgAN associated with autoimmune hepatitis (AIH) have seldom been reported. CASE SUMMARY:A 63-year-old Korean woman was admitted to Pusan National University Hospital for an evaluation of abdominal pain and elevated liver enzymes. Two weeks prior, she had presented to our hospital with proteinuria of approximately 1350 mg/d and hematuria and was diagnosed with IgAN. Autoimmune profiles were highly positive for antinuclear antibodies, and symptoms related to portal hypertension including ascites and peripheral edema were present. A diagnosis of AIH was made according to the simplified scoring system of the International Autoimmune Hepatitis Group. Despite immunosuppression with prednisolone and azathioprine, rapid deterioration of liver function led to end-stage liver disease. After a living-donor liver transplantation, liver function gradually improved, and she had maintained stable liver and kidney function at the six months follow-up. CONCLUSION:Cases of secondary IgAN with chronic liver disease have been frequently reported in the literature but are rarely associated with AIH. We encountered an IgAN patient with concurrent progressive liver failure due to AIH.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Jeon YH,Kim DW,Lee SJ,Park YJ,Kim HJ,Han M,Kim IY,Lee DW,Song SH,Lee SB,Seong EYdoi
10.12998/wjcc.v8.i17.3828subject
Has Abstractpub_date
2020-09-06 00:00:00pages
3828-3834issue
17issn
2307-8960journal_volume
8pub_type
abstract:BACKGROUND:Spontaneous peritonitis is one of the most common infectious complications in cirrhotic patients with ascites. Spontaneous fungal peritonitis (SFP) is a type of spontaneous peritonitis that is a less recognized but devastating complication in end-stage cirrhosis. Although high mortality was previously noted,...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i17.2438
更新日期:2019-09-06 00:00:00
abstract:BACKGROUND:We analyzed the main features of an infant diagnosed with temporary neonatal cyanosis in order to strengthen our understanding of the disease. CASE SUMMARY:We report a patient diagnosed with temporary neonatal cyanosis. The main clinical characteristics, gene mutation and treatment are discussed and a revie...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v8.i1.217
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abstract:BACKGROUND:Sinusoidal obstructive syndrome (SOS) is a disease that damages hepatic sinusoidal endothelial cells, resulting in progressive occlusion and fibrosis of the lobular central vein and the occurrence of intrahepatic sinusoidal portal hypertension. However, SOS after liver transplantation (LT) is uncommon and po...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v9.i2.489
更新日期:2021-01-16 00:00:00
abstract::IgG4-related disease (IgG4-RD) is an increasingly recognized pathological entity that tends to involve multiple organs with an elevated level of serum IgG4, which is easily misdiagnosed owing to sharing common clinical features with a variety of other diseases. Here, we report an interesting IgG4-RD case of a woman wi...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v6.i13.707
更新日期:2018-11-06 00:00:00
abstract::Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-year-old woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight T...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v6.i9.291
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abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v8.i19.4652
更新日期:2020-10-06 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v8.i2.318
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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更新日期:2019-08-06 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i4.658
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journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i6.215
更新日期:2014-06-16 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v2.i10.507
更新日期:2014-10-16 00:00:00
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journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v1.i7.217
更新日期:2013-10-16 00:00:00
abstract:BACKGROUND:A vascular tumor is a benign tumor with unique clinical and pathological features. Perirenal vascular tumor is extremely rare and has not yet been reported. Clinically, it manifests as soreness and swelling. Color ultrasound and renal angiography illustrated the perirenal mass, which was closely connected wi...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i10.2050
更新日期:2020-05-26 00:00:00
abstract:BACKGROUND:Uterine myomas are the most common benign gynecological soft tissue tumors in women but polycythemia associated with these tumors is rare. Polycythemia is significantly associated with risk of venous thromboembolism (VTE), which is further increased in case of a large pelvic mass and obesity. Here we report ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i19.3027
更新日期:2019-10-06 00:00:00
abstract::Primary mediastinal neuroendocrine tumors are a rare malignancy that accounts for < 10% of all mediastinal tumors. The case presented here involves a 52-year-old man who had been suffering for 3 mo from chronic cough, anorexia and substantial weight loss, as well as 2 wk of jaundice prior to his admission. A computed ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i10.915
更新日期:2015-10-16 00:00:00
abstract:AIM:To investigate the complex relationships between resting energy expenditure (REE), eating psychopathology, and Hypothalamus Pituitary Adrenal axis functioning in patients with eating disorders. METHODS:The study was designed as a cross-sectional survey, and it was planned by the Clinic for Eating Disorders of the ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v2.i7.257
更新日期:2014-07-16 00:00:00
abstract:BACKGROUND:Bortezomib is a first-line drug approved for patients with multiple myeloma (MM) and has significantly increased their overall survival. However, bortezomib-induced peripheral neuropathy (PN) remains a significant side effect that has led to its discontinuation in some patients. Guillain-Barré syndrome (GBS)...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i18.2905
更新日期:2019-09-26 00:00:00
abstract:BACKGROUND:Synchronous multiple primary cancers (SMPC) mean two or more malignant tumors occurring simultaneously and with different origins no matter what types they are or where they are located. The carcinogenesis of SMPC often involves variations of some specific genes. However, the correlation between CDH1 mutatio...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i13.1703
更新日期:2019-07-06 00:00:00
abstract:BACKGROUND:Sebaceous lymphadenoma is a benign tumor that occurs rarely in the salivary glands, most commonly in the parotid glands or periparotid lymph nodes, and even more rarely undergoes malignant transformation into a sebaceous lymphadenocarcinoma. CASE SUMMARY:We report an 82-year-old woman who presented with a p...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5751
更新日期:2020-11-26 00:00:00
abstract::Inflammation is a central process in several disorders and contributes to cancer progression. Inflammation involves a complex cascade of pro-inflammatory and anti-inflammatory signaling events with protein and lipid mediators. Recent advances in lipid detection have revealed the importance of lipid mediators in inflam...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v4.i7.155
更新日期:2016-07-16 00:00:00
abstract:BACKGROUND:Surgical treatment for large carotid body tumor (CBT), particularly the Shamblin III type, is challenging and rarely reported. CASE SUMMARY:In July 2014, a 63-year-old woman presented to our hospital with a large CBT (130 mm × 60 mm × 70 mm). The lesion was hypervascular, spanned from the first to the seven...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i16.2346
更新日期:2019-08-26 00:00:00
abstract:AIM:To investigated the association between the tumor cells' expression of E-cadherin and the numbers of several types of inflammatory cells infiltrating into the invasive portion of gallbladder cancer (GBC). METHODS:We analyzed 50 GBC cases for which a sufficient amount of tumor tissues for tissue microarray (TMA) ha...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v5.i1.1
更新日期:2017-01-16 00:00:00
abstract::Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The most common clinical presentation is an unilateral, discrete breast mass, nipple retraction and even a sinus formation often associated with an inflammation of the ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v2.i12.852
更新日期:2014-12-16 00:00:00
abstract:BACKGROUND:Primary chondrosarcoma of the liver are extremely rare. Moreover, there are few reports focusing on typical clinical symptoms and imaging characteristics. Therefore, the diagnosis of chondrosarcoma of the liver remains a challenge. CASE SUMMARY:A 59-year-old male was admitted due to a lesion occupying the r...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i20.5042
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Familial cases of autosomal recessive spastic ataxia of charlevoix-saguenay have not been reported in the Arabian Peninsula, although the consanguineous marriage rate is very high. We report the first family from the Arabian Peninsula harboring a novel frameshift mutation in the SACS gene. CASE SUMMARY:A 33...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i8.1477
更新日期:2020-04-26 00:00:00
abstract::The prevalence of nasopharyngeal carcinoma (NPC) is higher in southern China, Hong Kong, and Taiwan than in other areas in the world. Radiotherapy is an important part of treatment for NPC patients, especially those with stage III/IV disease. Subdural empyema is a rare but life-threatening complication in postradiothe...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i14.825
更新日期:2018-11-26 00:00:00
abstract:AIM:To investigate whether the change in pre-/post-operation serum alpha-fetoprotein (AFP) levels is a predictive factor for hepatocellular carcinoma (HCC) outcomes. METHODS:We retrospectively analyzed 334 HCC patients who underwent hepatic resection at our hospital between January 2006 and December 2016. The patients...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v6.i6.110
更新日期:2018-06-16 00:00:00
abstract::A 50-year-old male who underwent a HeartMate II left ventricular assist device placement for ischemic cardiomyopathy presented with discolored urine and hemolysis 3 mo after the operation. His hemolysis was thought to be due to thrombosis within the pump. Imaging studies were not able to visualize a left ventricular t...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i8.373
更新日期:2014-08-16 00:00:00
abstract:BACKGROUND:Inflammatory cytokines play a vital role in the occurrence of osteoarticular injury and inflammation. Whether inflammation-associated factors interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) are involved in the pathogenesis of keen articular cartilag...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i11.1262
更新日期:2019-06-06 00:00:00