Aetiology of idiopathic granulomatous mastitis.

Abstract:

:Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The most common clinical presentation is an unilateral, discrete breast mass, nipple retraction and even a sinus formation often associated with an inflammation of the overlying skin. The etiology of idiopathic granulomatous mastitis is still obscure. Its treatment remains controversial. The cause may be the autoimmune process, infection, a chemical reaction associated with oral contraceptive pills, or even lactation. Various factors, including hormonal imbalance, autoimmunity, unknown microbiological agents, smoking and α 1-antitrypsin deficiency have been suggested to play a role in disease aetiology. In this review, causing factors in the aetiology of idiopathic granulomatous mastitis are reviewed in detail.

journal_name

World J Clin Cases

authors

Altintoprak F,Kivilcim T,Ozkan OV

doi

10.12998/wjcc.v2.i12.852

subject

Has Abstract

pub_date

2014-12-16 00:00:00

pages

852-8

issue

12

issn

2307-8960

journal_volume

2

pub_type

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