Splenic hamartoma: A case report and review of the literature.

Abstract:

:Splenic hamartoma is a rare benign malformation, composed of an anomalous mixture of normal splenic elements, often found incidentally while working up other complaints or at autopsy. A splenic mass was incidentally found while evaluating the effects of a traffic accident in a 63-year-old woman. Abdominal computed tomography revealed a well-defined splenic mass with rim enhancement. The patient underwent splenectomy. The resected spleen contained a well-defined mass lesion measuring 3.5 cm × 3.0 cm. Microscopic examination revealed disorganized slit-like vascular channels lined by plump endothelial cells without atypia. The cells lining the vascular channels were positive for CD8, CD31, CD34 and vimentin. Endothelial cells that are positive for CD8 are a key feature that differentiates hamartoma from other vascular lesions of the spleen. Although this tumor is very rare, it must be included in the differential diagnosis of splenic mass-forming lesions.

journal_name

World J Clin Cases

authors

Sim J,Ahn HI,Han H,Jun YJ,Rehman A,Jang SM,Jang K,Paik SS

doi

10.12998/wjcc.v1.i7.217

subject

Has Abstract

pub_date

2013-10-16 00:00:00

pages

217-9

issue

7

issn

2307-8960

journal_volume

1

pub_type

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