Abstract:
:Although Kaposi sarcoma (KS) has been more traditionally considered an AIDS-defining illness, it may also be seen in individuals on immunosuppresive therapy. We report a case of a patient who presented to the hospital in the setting of increasingly refractory ulcerative colitis. Computed tomography scan of the abdomen was consistent with sigmoid diverticulititis and blood cultures were positive for Klebsiella. After a course of antibiotics with resolution of infection, a colonoscopy was performed to evaluate his diverticulitis and incidentally revealed a new rectal tumor. Immunohistochemistry showed the tumor was consistent with KS, with cells staining strongly positive for human herpesvirus-8. This case not only illustrates a rare case of KS found in an HIV-negative individual, but it also highlights the importance of considering an alternative diagnosis in a patient refractory to medical treatment. We discuss the management and care of an ulcerative colitis patient diagnosed with KS on immunosuppressive therapy.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Duh E,Fine Sdoi
10.12998/wjcc.v5.i12.423subject
Has Abstractpub_date
2017-12-16 00:00:00pages
423-427issue
12issn
2307-8960journal_volume
5pub_type
abstract:BACKGROUND:Giant paraesophageal hiatal hernias (HH) are very infrequent, and their spectrum of clinical manifestations is large. Giant HH mainly occurs in elderly patients, and its relationship with anemia has been reported. For the surgical treatment of large HH, Nissen fundoplication is the most common antireflux pro...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i6.1180
更新日期:2020-03-26 00:00:00
abstract:BACKGROUND:Myocardial bridge (MB) will compress the mural coronary artery (MCA) during the systole and cause myocardial ischemia. In the diagnosis of coronary heart disease (CHD), because the structure of MB is difficult to be observed by coronary angiography (CAG), the clinical study of the influence of MB on CHD is l...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i15.1986
更新日期:2019-08-06 00:00:00
abstract:BACKGROUND:Neurofibromatosis is an autosomal dominant genetic disorder with various manifestations. Systemic multiple neurofibromatosis is rare in infancy. The disease is difficult to identify in the early stage, and it is prone to misdiagnosis and missed diagnosis. In the presence of lower limb swelling with subcutane...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5678
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:Type A insulin resistance syndrome is a rare disorder caused by mutations in the gene encoding the insulin receptor. Its coexistence with ovarian serous papillary cystadenofibroma is even rarer. CASE SUMMARY:A 14-year-old girl developed type A insulin resistance syndrome and showed high fasting insulin, glu...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i15.3334
更新日期:2020-08-06 00:00:00
abstract::IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory disorder that can occur in almost all systemic organs and generally responds to corticosteroid treatment. We report a rare case of an IgG4-related intrapelvic mass lesion that responded to steroid therapy but caused a fistula between the sigmoid co...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i12.1000
更新日期:2015-12-16 00:00:00
abstract::Colorectal cancer (CRC) remains a major contributor to the number of cancer-related deaths that occur annually worldwide. With the development of molecular biology methods, an increasing number of molecular biomarkers have been identified and investigated. CRC is believed to result from an accumulation of epigenetic c...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v7.i19.2916
更新日期:2019-10-06 00:00:00
abstract:BACKGROUND:Heterotopic pancreas is a common lesion found in the gastrointestinal tract and is usually considered a benign disease. Reports of malignant change of heterotopic pancreas are scarce. CASE SUMMARY:A 44-year-old Chinese female underwent a gastroscopy to assess abdominal distension that had persisted for 2 mo...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i10.1979
更新日期:2020-05-26 00:00:00
abstract:BACKGROUND:Synovial sarcoma, a rare mesenchymal tumor type with unclear histological origin and direction of differentiation, accounts for 6%-10% of soft tissue tumors. It is mainly located near the joints and tendons of the limbs, and occurs primarily in children or young adults. Primary renal synovial sarcoma (PRSS) ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i19.3098
更新日期:2019-10-06 00:00:00
abstract::Gluten is one of the most abundant and widely distributed components of food in many areas. It can be included in wheat, barley, rye, and grains such as oats, barley, spelt, kamut, and triticale. Gluten-containing grains are widely consumed; in particular, wheat is one of the world's primary sources of food, providing...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i3.275
更新日期:2015-03-16 00:00:00
abstract:BACKGROUND:Aortic dissection (AD) is a life-threatening condition with a high mortality rate without immediate medical attention. Early diagnosis and appropriate treatment are critical in treating patients with AD. In the emergency department, patients with AD commonly present with classic symptoms of unanticipated sev...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v9.i1.232
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis, dermis and even subcutaneous tissue (including muscle and bones). First reported by Cordon in 1767, ACC is a rare disease with a low incidence of 1/100000 to 3/10000. Curren...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i17.2611
更新日期:2019-09-06 00:00:00
abstract::Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-year-old woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight T...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i9.291
更新日期:2018-09-06 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) has been advocated by digestive endoscopists because of its comparable therapeutic effect to surgery, reduced trauma, faster recovery, and fewer complications. However, ESD for lesions of the duodenum is more challenging than those occurring at other levels of the gastr...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i24.6296
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Afferent loop syndrome (ALS) is a rare mechanical complication that occurs after reconstruction of the stomach or esophagus to the jejunum, such as Billroth II gastrojejunostomy, Roux-en-Y gastrojejunostomy, or Roux-en-Y esophagoje-junostomy. Traditionally, an operation is the first choice for benign causes....
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i21.5353
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:Waldenström macroglobulinemia (WM) is a type of small lymphocytic lymphoma that mainly affects the bone marrow, spleen, and lymph nodes. A subset of patients with WM demonstrates extramedullary involvement (4.4%), and the most frequent extramedullary disease site involved is the lungs (30%). CASE SUMMARY:A ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i11.2305
更新日期:2020-06-06 00:00:00
abstract::Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders caused by collagen synthesis defects. Several hemostatic abnormalities have been described in EDS patients that increase the bleeding tendencies of these patients. This case report illustrates a patient with an unusual presentation of a p...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i3.75
更新日期:2014-03-16 00:00:00
abstract:BACKGROUND:Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor that is characterized by spindle cells differentiated from muscle fibroblasts and infiltration of various types of inflammatory cells. IMT can occur at any age and at any anatomic site. The most common location of IMT is the bladder in the ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i24.4366
更新日期:2019-12-26 00:00:00
abstract:BACKGROUND:Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare skin disorder that may be associated with cancer. CASE SUMMARY:A 58-year-old female presented with a cholestatic syndrome and significant weight loss three months before admission. Five months earlier, she had abruptly develope...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i18.4122
更新日期:2020-09-26 00:00:00
abstract:BACKGROUND:Small cell lung cancer (SCLC) accounts for 15% of lung cancers, and it commonly expresses peptide and protein factors that are active as hormones. These secreting factors manifest as paraneoplastic disorders, such as ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS). The clinical features are abnorma...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v7.i10.1177
更新日期:2019-05-26 00:00:00
abstract:BACKGROUND:Fecal microbiota transplantation (FMT) is the administration of fecal bacterial liquid from healthy donors to a recipient's digestive tract, which is recommended as a therapeutic method for recurrent Clostridium difficile infection (CDI). Many clinical trials focusing on different diseases are in progress. T...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v6.i16.1121
更新日期:2018-12-26 00:00:00
abstract::In commenting on a case report of a 55-year-old man who suffered Takotsubo syndrome (TTS), in the setting of receiving chemotherapy with cytarabine and daunorubicin for acute myeloid leukemia, the author expresses his views that TTS in the setting of chemotherapy for malignancies may not be chemotherapeutic drug-speci...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v3.i2.204
更新日期:2015-02-16 00:00:00
abstract:BACKGROUND:Concomitant allergic fungal rhinosinusitis (AFRS) and allergic bronchopulmonary aspergillosis (ABPA) are extremely rare, with no more than 20 cases reported in the English literature. CASE SUMMARY:A 52-year-old female patient complained of right-sided nasal obstruction, rhinorrhea, sneezing, epistaxis, and ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i22.3821
更新日期:2019-11-26 00:00:00
abstract:BACKGROUND:The global pandemic of coronavirus disease 2019 pneumonia poses a particular challenge to the emergency surgical treatment of elderly patients with high-risk acute abdominal diseases. Elderly patients are a high-risk group for surgical treatment. If the incarceration of gallstones cannot be relieved, emergen...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i20.4908
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i19.4652
更新日期:2020-10-06 00:00:00
abstract:BACKGROUND:Fishbone is the most common esophageal foreign body and tends to migrate after piercing the esophagus to nearby structures. Vascular injury around the esophagus is a serious complication and has a high mortality rate, especially in the case of multiple vascular injuries. CASE SUMMARY:We report an extremely ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i20.4981
更新日期:2020-10-26 00:00:00
abstract::Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate tha...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i7.575
更新日期:2015-07-16 00:00:00
abstract::Inflammatory bowel disease (IBD) is a chronic immune-mediated disease that affects the gastrointestinal tract. It is argued that environment, microbiome, and immune-mediated factors interact in a genetically susceptible host to trigger IBD. Recently, there has been increased interest in the development, progression, a...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v9.i2.321
更新日期:2021-01-16 00:00:00
abstract:BACKGROUND:There is a common pathologic relationship between parathyroid adenoma and thyroid cancer, but this relationship is infrequent in pregnant patients with primary hyperparathyroidism (PHPT). CASE SUMMARY:A 27-year-old gravida 1 woman was transferred to our hospital at 16 wk of pregnancy. She was diagnosed with...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i21.5426
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:Adrenocortical cancer (ACC) is an infrequent and often aggressive malignancy with a very poor prognosis. It can be classified as functional or nonfunctional. Nonfunctional ACC is hampered by the absence of specific signs or symptoms; only abdominal pain with or without incidental adrenal occupation is typica...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i15.2075
更新日期:2019-08-06 00:00:00
abstract:BACKGROUND:Breast cancer (BCa) is one of the most common malignancies in women; however, ureteral metastasis of BCa has rarely been reported in the literature. CASE SUMMARY:A 55-year-old Chinese woman with an 8-year history of BCa presented with lower back pain that had persisted for 3 mo. The patient underwent bilate...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i20.3347
更新日期:2019-10-26 00:00:00