Homozygous factor V Leiden mutation in type IV Ehlers-Danlos patient.

Abstract:

:Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders caused by collagen synthesis defects. Several hemostatic abnormalities have been described in EDS patients that increase the bleeding tendencies of these patients. This case report illustrates a patient with an unusual presentation of a patient with type IV EDS, platelet δ-storage pool disease and factor V Leiden mutation. Young woman having previous bilateral deep vein thrombosis and pulmonary emboli coexisting with ruptured splenic aneurysm and multiple other aneurysms now presented with myocardial infarction. Presence of factor V Leiden mutation raises the possibility that the infarct was due to acute coronary thrombosis, although coronary artery aneurysm and dissection with myocardial infarction is known to occur in vascular type EDS. This is the first report in the medical literature of factor V Leiden mutation in an EDS patient which made the management of our patient challenging with propensity to both bleeding and clotting.

journal_name

World J Clin Cases

authors

Refaat M,Hotait M,Winston B

doi

10.12998/wjcc.v2.i3.75

subject

Has Abstract

pub_date

2014-03-16 00:00:00

pages

75-7

issue

3

issn

2307-8960

journal_volume

2

pub_type

  • Acetaminophen-induced acute pancreatitis: A case report and literature review.

    abstract::Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-year-old woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight T...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v6.i9.291

    authors: He YH,Lu L,Wang YF,Huang JS,Zhu WQ,Guo Y,Li CX,Li HM

    更新日期:2018-09-06 00:00:00

  • Challenging rescue of a 4 years old boy with H1N1 infection by extracorporeal membrane oxygenator: A case report.

    abstract:INTRODUCTION:World Health Organization announced on April 2009 a public health emergency of international concern caused by swine-origin influenza A (H1N1) virus. Acute respiratory distress syndrome (ARDS) has been reported to be the most devastating complications of this pathogen. Extracorporeal membrane oxygenator (E...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v2.i10.578

    authors: Papadopoulos N,Martens S,Keller H,El-Sayed Ahmad A,Moritz A,Zierer A

    更新日期:2014-10-16 00:00:00

  • Proliferative verrucous leukoplakia may initially mimic lichenoid reactions.

    abstract::Proliferative verrucous leukoplakia is an intriguing disease, which occurs particularly in women aged greater than 60 years, is not associated with tobacco and alcohol, and has a high risk of recurrence and malignant transformation. Although it is well known that the typical presentation is characterized by multifocal...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v3.i10.861

    authors: Lopes MA,Feio P,Santos-Silva AR,Vargas PA

    更新日期:2015-10-16 00:00:00

  • Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma: A case report.

    abstract:BACKGROUND:Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare skin disorder that may be associated with cancer. CASE SUMMARY:A 58-year-old female presented with a cholestatic syndrome and significant weight loss three months before admission. Five months earlier, she had abruptly develope...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i18.4122

    authors: Lemaire CC,Portilho ALC,Pinheiro LV,Vivas RA,Britto M,Montenegro M,Rodrigues LFF,Arruda S,Lyra AC,Cavalcante LN

    更新日期:2020-09-26 00:00:00

  • Prosthodontic management of hemimandibulectomy patients to restore form and function - A case series.

    abstract::Surgical resection of mandible owing to benign, malignant neoplasm, osteoradionecrosis is common. The resection can be total or segmental depending on the lesion. Loss of mandibular continuity causes deviation of remaining mandibular segment towards the resected side and rotation inferiorly due to muscle pull and scar...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v5.i10.384

    authors: Lingeshwar D,Appadurai R,Sswedheni U,Padmaja C

    更新日期:2017-10-16 00:00:00

  • Health care associated infections, antibiotic resistance and clinical outcome: A surveillance study from Sanandaj, Iran.

    abstract:AIM:To study the antibiotic susceptibility patterns of gram-negative healthcare associated bacterial infections at two tertiary hospitals in the Sanandaj city, Kurdistan Province, Iran. METHODS:From January 2012 to December 2012, all positive cultures from potentially sterile body fluids were gathered. They sent to pr...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v4.i3.63

    authors: Soltani J,Poorabbas B,Miri N,Mardaneh J

    更新日期:2016-03-16 00:00:00

  • Endoscopic retrograde cholangiopancreatography in elderly patients: Difficult cannulation and adverse events.

    abstract:BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) is a valuable therapeutic technique for pancreatobiliary diseases, and its application in the elderly is no longer limited. However, a higher incidence of procedure difficulty and periprocedural adverse events might be expected in elderly patients due to ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v8.i14.2988

    authors: Tabak F,Wang HS,Li QP,Ge XX,Wang F,Ji GZ,Miao L

    更新日期:2020-07-26 00:00:00

  • Association between functional abdominal pain disorders and asthma in adolescents: A cross-sectional study.

    abstract:AIM:To find the association between asthma and different types of functional abdominal pain disorders (FAPDs) among teenagers.METHODA cross-sectional study was conducted among 13 to 15-year-old children from six randomly selected schools in Anuradhapura district of Sri Lanka. Data were collected using translated and va...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v6.i15.944

    authors: Kumari MV,Devanarayana NM,Amarasiri L,Rajindrajith S

    更新日期:2018-12-06 00:00:00

  • Accuracy study of a binocular-stereo-vision-based navigation robot for minimally invasive interventional procedures.

    abstract:BACKGROUND:Medical robot is a promising surgical tool, but no specific one has been designed for interventional treatment of chronic pain. We developed a computed tomography-image based navigation robot using a new registration method with binocular vision. This kind of robot is appropriate for minimal invasive interve...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v8.i16.3440

    authors: Wang R,Han Y,Luo MZ,Wang NK,Sun WW,Wang SC,Zhang HD,Lu LJ

    更新日期:2020-08-26 00:00:00

  • Small-cell neuroendocrine carcinoma of the rectum - a rare tumor type with poor prognosis: A case report and review of literature.

    abstract:BACKGROUND:Small-cell neuroendocrine carcinoma (SNEC) of the rectum is a rare tumor associated with poor prognosis. CASE SUMMARY:We report a case of a 77-year-old male who came into our hospital because of blood with his stool. An endoscopy revealed a cauliflower-like neoplasm in his rectum. Imaging examination showed...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i23.6095

    authors: Chen ZZ,Huang W,Wei ZQ

    更新日期:2020-12-06 00:00:00

  • Sebaceous lymphadenocarcinoma of the parotid gland: A case report.

    abstract:BACKGROUND:Sebaceous lymphadenoma is a benign tumor that occurs rarely in the salivary glands, most commonly in the parotid glands or periparotid lymph nodes, and even more rarely undergoes malignant transformation into a sebaceous lymphadenocarcinoma. CASE SUMMARY:We report an 82-year-old woman who presented with a p...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i22.5751

    authors: Hao FY,Wang YL,Li SM,Xue LF

    更新日期:2020-11-26 00:00:00

  • Adrenal metastasis from endometrial cancer: A case report.

    abstract:BACKGROUND:Metastases to adrenal glands originate principally from lung, breast, or gastrointestinal cancers, followed by malignant melanoma and thyroid neoplasms. We present an unusual case of uterine cancer metastasizing to the adrenal glands with a review of the English literature on the management of this rare dise...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v7.i14.1844

    authors: Da Dalt G,Friziero A,Grego A,Serafini S,Fassina A,Blandamura S,Sperti C

    更新日期:2019-07-26 00:00:00

  • Intravesically instilled gemcitabine-induced lung injury in a patient with invasive urothelial carcinoma: A case report.

    abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i19.4652

    authors: Zhou XM,Wu C,Gu X

    更新日期:2020-10-06 00:00:00

  • Pulmonary benign metastasizing leiomyoma: A case report and review of the literature.

    abstract:BACKGROUND:Pulmonary benign metastatic leiomyoma (PBML), which is very rare, is a type of benign metastatic leiomyoma (BML). Here, we report a case of PBML, finally diagnosed through multidisciplinary team (MDT) discussions, and provide a literature review of the disease. CASE SUMMARY:A 55-year old asymptomatic woman ...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i14.3082

    authors: Dai HY,Guo SL,Shen J,Yang L

    更新日期:2020-07-26 00:00:00

  • Synchronous parathyroid adenoma, papillary thyroid carcinoma and thyroid adenoma in pregnancy: A case report.

    abstract:BACKGROUND:There is a common pathologic relationship between parathyroid adenoma and thyroid cancer, but this relationship is infrequent in pregnant patients with primary hyperparathyroidism (PHPT). CASE SUMMARY:A 27-year-old gravida 1 woman was transferred to our hospital at 16 wk of pregnancy. She was diagnosed with...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i21.5426

    authors: Li Q,Xu XZ,Shi JH

    更新日期:2020-11-06 00:00:00

  • Application of Newcastle disease virus in the treatment of colorectal cancer.

    abstract::Colorectal cancer (CRC) is one of the main reasons of tumor-related deaths worldwide. At present, the main treatment is surgery, but the results are unsatisfactory, and the prognosis is poor. The majority of patients die due to liver or lung metastasis or recurrence. In recent years, great progress has been made in th...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审

    doi:10.12998/wjcc.v7.i16.2143

    authors: Song H,Zhong LP,He J,Huang Y,Zhao YX

    更新日期:2019-08-26 00:00:00

  • Application of endoscopic submucosal dissection in duodenal space-occupying lesions.

    abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) has been advocated by digestive endoscopists because of its comparable therapeutic effect to surgery, reduced trauma, faster recovery, and fewer complications. However, ESD for lesions of the duodenum is more challenging than those occurring at other levels of the gastr...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v8.i24.6296

    authors: Li XY,Ji KY,Qu YH,Zheng JJ,Guo YJ,Zhang CP,Zhang KP

    更新日期:2020-12-26 00:00:00

  • Underwater vs conventional endoscopic mucosal resection in treatment of colorectal polyps: A meta-analysis.

    abstract:BACKGROUND:Underwater endoscopic mucosal resection (UEMR) of colorectal lesions is emerging as an alternative method to conventional endoscopic mucosal resection (EMR); however, it is still controversial whether there is a difference in the effectiveness between UEMR and EMR. AIM:To evaluate the effectiveness and safe...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v8.i20.4826

    authors: Ni DQ,Lu YP,Liu XQ,Gao LY,Huang X

    更新日期:2020-10-26 00:00:00

  • Pre- and intraoperative predictors of acute kidney injury after liver transplantation.

    abstract:BACKGROUND:Acute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity and mortality. Risk factors for AKI after LT still need to be clarified. AIM:To identify the predictors of acute kidney injury after liver transplantation. METHODS:The frequency ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v8.i18.4034

    authors: Mrzljak A,Franusic L,Pavicic-Saric J,Kelava T,Jurekovic Z,Kocman B,Mikulic D,Budimir-Bekan I,Knotek M

    更新日期:2020-09-26 00:00:00

  • Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair.

    abstract::The gold standard of peripheral nerve repair is nerve autograft when tensionless repair is not possible. Use of nerve autograft has several shortcomings, however. These include limited availability of donor tissue, sacrifice of a functional nerve, and possible neuroma formation. In order to address these deficiencies,...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审

    doi:10.12998/wjcc.v3.i2.141

    authors: Gerth DJ,Tashiro J,Thaller SR

    更新日期:2015-02-16 00:00:00

  • Surgical resection of a large hypopharyngeal hemangioma in an adult using neodymium-doped yttrium aluminum garnet laser: A case report.

    abstract:BACKGROUND:Generally, hemangiomas do not require surgical intervention; however, cases of large hemangiomas, potentially involving the throat and trachea, necessitate surgical therapy. Here, we present a case of hypopharyngeal hemangioma in an adult that was successfully treated with neodymium-doped yttrium aluminum ga...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i5.932

    authors: Jin M,Wang CY,Da YX,Zhu W,Jiang H

    更新日期:2020-03-06 00:00:00

  • Correlation analysis of collagen proportionate area in Budd-Chiari syndrome: A preliminary clinicopathological study.

    abstract:BACKGROUND:Collagen proportionate area (CPA) is an important index for assessing the severity of liver fibrosis. Budd-Chiari syndrome can frequently progress to liver fibrosis and cirrhosis. CPA might play an important role in the pathological progress of Budd-Chiari syndrome. AIM:To explore the role of CPA in predict...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v7.i2.130

    authors: He FL,Li C,Liu FQ,Qi XS

    更新日期:2019-01-26 00:00:00

  • Dynamic mechanical allodynia following finger amputation: Unexpected skin hyperinnervation.

    abstract::The development of chronic pain after amputations is not an uncommon event. In some cases the most disabling problem is represented by the symptom called dynamic mechanical allodynia, characterized by the painful sensation evoked by gently stroking the skin. Despite the growing interest in understanding pain mechanism...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v1.i6.197

    authors: Buonocore M,Gagliano MC,Bonezzi C

    更新日期:2013-09-16 00:00:00

  • Differential diagnosis of a vanishing brain space occupying lesion in a child.

    abstract::We describe clinical, diagnostic features and follow up of a patient with a vanishing brain lesion. A 14-year-old child admitted to the department of Neurology at September 2009 with a history of subacute onset of fever, anorexia, vomiting, blurring of vision and right hemiparesis since one month. Magnetic resonance i...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v3.i11.956

    authors: Hamed SA,Mekkawy MA,Abozaid H

    更新日期:2015-11-16 00:00:00

  • Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis.

    abstract:AIM:To investigated the association between the tumor cells' expression of E-cadherin and the numbers of several types of inflammatory cells infiltrating into the invasive portion of gallbladder cancer (GBC). METHODS:We analyzed 50 GBC cases for which a sufficient amount of tumor tissues for tissue microarray (TMA) ha...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章

    doi:10.12998/wjcc.v5.i1.1

    authors: Kai K,Masuda M,Aishima S

    更新日期:2017-01-16 00:00:00

  • Idiopathic adulthood ductopenia with elevated transaminase only: A case report.

    abstract:BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-yea...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i24.6524

    authors: Zhang XC,Wang D,Li X,Hu YL,Wang C

    更新日期:2020-12-26 00:00:00

  • Jejunal cavernous lymphangioma manifested as gastrointestinal bleeding with hypogammaglobulinemia in adult: A case report and literature review.

    abstract:BACKGROUND:Lymphangioma is a benign lesion that rarely involves the gastrointestinal tract, especially in adults. Small bowel lymphangioma is a rare cause of gastrointestinal bleeding. Here, we report a case of an adult diagnosed with jejunal lymphangioma presenting with melena, anemia and hypogammaglobulinemia. We als...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v8.i1.140

    authors: Tan B,Zhang SY,Wang YN,Li Y,Shi XH,Qian JM

    更新日期:2020-01-06 00:00:00

  • Nutritional deficiencies in the pediatric age group in a multicultural developed country, Israel.

    abstract::Nutrient deficiencies are prevalent worldwide. Diseases and morbid conditions have been described to result from nutritional deficiencies. It is essential to address nutrient deficiencies as these may lead to chronic long-term health problems such as rickets, iron deficiency anemia, goiter, obesity, coronary heart dis...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审

    doi:10.12998/wjcc.v2.i5.120

    authors: Haimi M,Lerner A

    更新日期:2014-05-16 00:00:00

  • Gut microbiota and inflammatory bowel disease: The current status and perspectives.

    abstract::Inflammatory bowel disease (IBD) is a chronic immune-mediated disease that affects the gastrointestinal tract. It is argued that environment, microbiome, and immune-mediated factors interact in a genetically susceptible host to trigger IBD. Recently, there has been increased interest in the development, progression, a...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审

    doi:10.12998/wjcc.v9.i2.321

    authors: Zheng L,Wen XL

    更新日期:2021-01-16 00:00:00

  • Sustained complete response to erlotinib in squamous cell carcinoma of the head and neck: A case report.

    abstract:BACKGROUND:Squamous cell carcinoma of head and neck (SCCHN) is the fifth most common cancer worldwide. Inhibition of epidermal growth factor receptor signaling has been shown to be a critical component of therapeutic option. Herein, we report a case of durable complete response to erlotinib. CASE SUMMARY:An 81-year-ol...

    journal_title:World journal of clinical cases

    pub_type:

    doi:10.12998/wjcc.v7.i5.616

    authors: Thinn MM,Hsueh CT,Hsueh CT

    更新日期:2019-03-06 00:00:00