Abstract:
:Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders caused by collagen synthesis defects. Several hemostatic abnormalities have been described in EDS patients that increase the bleeding tendencies of these patients. This case report illustrates a patient with an unusual presentation of a patient with type IV EDS, platelet δ-storage pool disease and factor V Leiden mutation. Young woman having previous bilateral deep vein thrombosis and pulmonary emboli coexisting with ruptured splenic aneurysm and multiple other aneurysms now presented with myocardial infarction. Presence of factor V Leiden mutation raises the possibility that the infarct was due to acute coronary thrombosis, although coronary artery aneurysm and dissection with myocardial infarction is known to occur in vascular type EDS. This is the first report in the medical literature of factor V Leiden mutation in an EDS patient which made the management of our patient challenging with propensity to both bleeding and clotting.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Refaat M,Hotait M,Winston Bdoi
10.12998/wjcc.v2.i3.75subject
Has Abstractpub_date
2014-03-16 00:00:00pages
75-7issue
3issn
2307-8960journal_volume
2pub_type
abstract::Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-year-old woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight T...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i9.291
更新日期:2018-09-06 00:00:00
abstract:INTRODUCTION:World Health Organization announced on April 2009 a public health emergency of international concern caused by swine-origin influenza A (H1N1) virus. Acute respiratory distress syndrome (ARDS) has been reported to be the most devastating complications of this pathogen. Extracorporeal membrane oxygenator (E...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i10.578
更新日期:2014-10-16 00:00:00
abstract::Proliferative verrucous leukoplakia is an intriguing disease, which occurs particularly in women aged greater than 60 years, is not associated with tobacco and alcohol, and has a high risk of recurrence and malignant transformation. Although it is well known that the typical presentation is characterized by multifocal...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v3.i10.861
更新日期:2015-10-16 00:00:00
abstract:BACKGROUND:Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare skin disorder that may be associated with cancer. CASE SUMMARY:A 58-year-old female presented with a cholestatic syndrome and significant weight loss three months before admission. Five months earlier, she had abruptly develope...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i18.4122
更新日期:2020-09-26 00:00:00
abstract::Surgical resection of mandible owing to benign, malignant neoplasm, osteoradionecrosis is common. The resection can be total or segmental depending on the lesion. Loss of mandibular continuity causes deviation of remaining mandibular segment towards the resected side and rotation inferiorly due to muscle pull and scar...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v5.i10.384
更新日期:2017-10-16 00:00:00
abstract:AIM:To study the antibiotic susceptibility patterns of gram-negative healthcare associated bacterial infections at two tertiary hospitals in the Sanandaj city, Kurdistan Province, Iran. METHODS:From January 2012 to December 2012, all positive cultures from potentially sterile body fluids were gathered. They sent to pr...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v4.i3.63
更新日期:2016-03-16 00:00:00
abstract:BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) is a valuable therapeutic technique for pancreatobiliary diseases, and its application in the elderly is no longer limited. However, a higher incidence of procedure difficulty and periprocedural adverse events might be expected in elderly patients due to ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i14.2988
更新日期:2020-07-26 00:00:00
abstract:AIM:To find the association between asthma and different types of functional abdominal pain disorders (FAPDs) among teenagers.METHODA cross-sectional study was conducted among 13 to 15-year-old children from six randomly selected schools in Anuradhapura district of Sri Lanka. Data were collected using translated and va...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v6.i15.944
更新日期:2018-12-06 00:00:00
abstract:BACKGROUND:Medical robot is a promising surgical tool, but no specific one has been designed for interventional treatment of chronic pain. We developed a computed tomography-image based navigation robot using a new registration method with binocular vision. This kind of robot is appropriate for minimal invasive interve...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i16.3440
更新日期:2020-08-26 00:00:00
abstract:BACKGROUND:Small-cell neuroendocrine carcinoma (SNEC) of the rectum is a rare tumor associated with poor prognosis. CASE SUMMARY:We report a case of a 77-year-old male who came into our hospital because of blood with his stool. An endoscopy revealed a cauliflower-like neoplasm in his rectum. Imaging examination showed...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i23.6095
更新日期:2020-12-06 00:00:00
abstract:BACKGROUND:Sebaceous lymphadenoma is a benign tumor that occurs rarely in the salivary glands, most commonly in the parotid glands or periparotid lymph nodes, and even more rarely undergoes malignant transformation into a sebaceous lymphadenocarcinoma. CASE SUMMARY:We report an 82-year-old woman who presented with a p...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5751
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:Metastases to adrenal glands originate principally from lung, breast, or gastrointestinal cancers, followed by malignant melanoma and thyroid neoplasms. We present an unusual case of uterine cancer metastasizing to the adrenal glands with a review of the English literature on the management of this rare dise...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i14.1844
更新日期:2019-07-26 00:00:00
abstract:BACKGROUND:Gemcitabine is a chemotherapy agent with relatively low toxicities, as a valid option for elderly patients with underlying diseases. Gemcitabine-induced pulmonary toxicities are rare and various, ranging from self-limited episodes of bronchospasm to fatal, progressive, severe, interstitial pneumonitis and re...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i19.4652
更新日期:2020-10-06 00:00:00
abstract:BACKGROUND:Pulmonary benign metastatic leiomyoma (PBML), which is very rare, is a type of benign metastatic leiomyoma (BML). Here, we report a case of PBML, finally diagnosed through multidisciplinary team (MDT) discussions, and provide a literature review of the disease. CASE SUMMARY:A 55-year old asymptomatic woman ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i14.3082
更新日期:2020-07-26 00:00:00
abstract:BACKGROUND:There is a common pathologic relationship between parathyroid adenoma and thyroid cancer, but this relationship is infrequent in pregnant patients with primary hyperparathyroidism (PHPT). CASE SUMMARY:A 27-year-old gravida 1 woman was transferred to our hospital at 16 wk of pregnancy. She was diagnosed with...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i21.5426
更新日期:2020-11-06 00:00:00
abstract::Colorectal cancer (CRC) is one of the main reasons of tumor-related deaths worldwide. At present, the main treatment is surgery, but the results are unsatisfactory, and the prognosis is poor. The majority of patients die due to liver or lung metastasis or recurrence. In recent years, great progress has been made in th...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v7.i16.2143
更新日期:2019-08-26 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) has been advocated by digestive endoscopists because of its comparable therapeutic effect to surgery, reduced trauma, faster recovery, and fewer complications. However, ESD for lesions of the duodenum is more challenging than those occurring at other levels of the gastr...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i24.6296
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Underwater endoscopic mucosal resection (UEMR) of colorectal lesions is emerging as an alternative method to conventional endoscopic mucosal resection (EMR); however, it is still controversial whether there is a difference in the effectiveness between UEMR and EMR. AIM:To evaluate the effectiveness and safe...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i20.4826
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity and mortality. Risk factors for AKI after LT still need to be clarified. AIM:To identify the predictors of acute kidney injury after liver transplantation. METHODS:The frequency ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i18.4034
更新日期:2020-09-26 00:00:00
abstract::The gold standard of peripheral nerve repair is nerve autograft when tensionless repair is not possible. Use of nerve autograft has several shortcomings, however. These include limited availability of donor tissue, sacrifice of a functional nerve, and possible neuroma formation. In order to address these deficiencies,...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i2.141
更新日期:2015-02-16 00:00:00
abstract:BACKGROUND:Generally, hemangiomas do not require surgical intervention; however, cases of large hemangiomas, potentially involving the throat and trachea, necessitate surgical therapy. Here, we present a case of hypopharyngeal hemangioma in an adult that was successfully treated with neodymium-doped yttrium aluminum ga...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i5.932
更新日期:2020-03-06 00:00:00
abstract:BACKGROUND:Collagen proportionate area (CPA) is an important index for assessing the severity of liver fibrosis. Budd-Chiari syndrome can frequently progress to liver fibrosis and cirrhosis. CPA might play an important role in the pathological progress of Budd-Chiari syndrome. AIM:To explore the role of CPA in predict...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i2.130
更新日期:2019-01-26 00:00:00
abstract::The development of chronic pain after amputations is not an uncommon event. In some cases the most disabling problem is represented by the symptom called dynamic mechanical allodynia, characterized by the painful sensation evoked by gently stroking the skin. Despite the growing interest in understanding pain mechanism...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v1.i6.197
更新日期:2013-09-16 00:00:00
abstract::We describe clinical, diagnostic features and follow up of a patient with a vanishing brain lesion. A 14-year-old child admitted to the department of Neurology at September 2009 with a history of subacute onset of fever, anorexia, vomiting, blurring of vision and right hemiparesis since one month. Magnetic resonance i...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v3.i11.956
更新日期:2015-11-16 00:00:00
abstract:AIM:To investigated the association between the tumor cells' expression of E-cadherin and the numbers of several types of inflammatory cells infiltrating into the invasive portion of gallbladder cancer (GBC). METHODS:We analyzed 50 GBC cases for which a sufficient amount of tumor tissues for tissue microarray (TMA) ha...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v5.i1.1
更新日期:2017-01-16 00:00:00
abstract:BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-yea...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i24.6524
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Lymphangioma is a benign lesion that rarely involves the gastrointestinal tract, especially in adults. Small bowel lymphangioma is a rare cause of gastrointestinal bleeding. Here, we report a case of an adult diagnosed with jejunal lymphangioma presenting with melena, anemia and hypogammaglobulinemia. We als...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i1.140
更新日期:2020-01-06 00:00:00
abstract::Nutrient deficiencies are prevalent worldwide. Diseases and morbid conditions have been described to result from nutritional deficiencies. It is essential to address nutrient deficiencies as these may lead to chronic long-term health problems such as rickets, iron deficiency anemia, goiter, obesity, coronary heart dis...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v2.i5.120
更新日期:2014-05-16 00:00:00
abstract::Inflammatory bowel disease (IBD) is a chronic immune-mediated disease that affects the gastrointestinal tract. It is argued that environment, microbiome, and immune-mediated factors interact in a genetically susceptible host to trigger IBD. Recently, there has been increased interest in the development, progression, a...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v9.i2.321
更新日期:2021-01-16 00:00:00
abstract:BACKGROUND:Squamous cell carcinoma of head and neck (SCCHN) is the fifth most common cancer worldwide. Inhibition of epidermal growth factor receptor signaling has been shown to be a critical component of therapeutic option. Herein, we report a case of durable complete response to erlotinib. CASE SUMMARY:An 81-year-ol...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i5.616
更新日期:2019-03-06 00:00:00