Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair.

Abstract:

:The gold standard of peripheral nerve repair is nerve autograft when tensionless repair is not possible. Use of nerve autograft has several shortcomings, however. These include limited availability of donor tissue, sacrifice of a functional nerve, and possible neuroma formation. In order to address these deficiencies, researchers have developed a variety of biomaterials available for repair of peripheral nerve gaps. We review the clinical studies published in the English literature detailing outcomes and reconstructive options. Regardless of the material used or the type of nerve repaired, outcomes are generally similar to nerve autograft in gaps less than 3 cm. New biomaterials currently under preclinical evaluation may provide improvements in outcomes.

journal_name

World J Clin Cases

authors

Gerth DJ,Tashiro J,Thaller SR

doi

10.12998/wjcc.v3.i2.141

subject

Has Abstract

pub_date

2015-02-16 00:00:00

pages

141-7

issue

2

issn

2307-8960

journal_volume

3

pub_type

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