Abstract:
BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-year-old woman with elevation of transaminases and alkaline phosphatase without clinical symptoms. Five years ago, the patient had abnormal transaminases but no cholestasis. Three months before admission, physical examination revealed an increase in transaminases. Oral hepatoprotective drugs did not show any significant improvement, and she was admitted to hospital for further diagnosis and treatment. Liver biopsy confirmed IAD. After about 2 wk of ursodeoxycholic acid treatment, serological and histological examination showed a significant response. CONCLUSION:IAD is a manifestation of cholestasis, but also may be an abnormal increase in transaminase in the early stage.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Zhang XC,Wang D,Li X,Hu YL,Wang Cdoi
10.12998/wjcc.v8.i24.6524subject
Has Abstractpub_date
2020-12-26 00:00:00pages
6524-6528issue
24issn
2307-8960journal_volume
8pub_type
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v6.i13.707
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journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v1.i1.37
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
pub_type:
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