Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.

abstract：:Despite evolutionary musicology's interdisciplinary nature, and the diverse methods it employs, the field has nevertheless tended to divide into two main positions. Some argue that music should be understood as a naturally selected adaptation, while others claim that music is a product of culture with little or no rel...

journal_title：Frontiers in neuroscience

authors： van der Schyff D,Schiavio A

更新日期：2017-09-29 00:00:00

abstract：:Hemispheric asymmetry of hippocampal volume is a common finding that has biological relevance, including associations with dementia and cognitive performance. However, a recent study has reported the possibility of systematic error in measurements of hippocampal asymmetry by magnetic resonance volumetry. We manually t...

journal_title：Frontiers in neuroscience

authors： Rogers BP,Sheffield JM,Luksik AS,Heckers S

更新日期：2012-12-13 00:00:00

abstract：:Neurons are generated during embryonic development and in adulthood, although adult neurogenesis is restricted to two main brain regions, the hippocampus and olfactory bulb. The subventricular zone (SVZ) of the lateral ventricles generates neural stem/progenitor cells that continually provide the olfactory bulb (OB) w...

journal_title：Frontiers in neuroscience

authors： Figueres-Oñate M,López-Mascaraque L

更新日期：2016-05-09 00:00:00

abstract：:The neuropeptide oxytocin (OT) plays an important role in the regulation of social and anxiety-like behavior. Our previous studies have shown that OT neurons send projections from the hypothalamus to the dorsolateral bed nucleus of the stria terminalis (BNSTdl), a forebrain region critically involved in the modulation...

journal_title：Frontiers in neuroscience

authors： Martinon D,Dabrowska J

更新日期：2018-03-21 00:00:00

abstract：:The neuropeptide oxytocin plays a central role in prosocial and parental behavior in non-human mammals as well as humans. It has been suggested that oxytocin may affect visual processing of infant faces and emotional reaction to infants. Healthy male volunteers (N = 13) were tested for their ability to detect infant o...

journal_title：Frontiers in neuroscience

authors： Saito A,Hamada H,Kikusui T,Mogi K,Nagasawa M,Mitsui S,Higuchi T,Hasegawa T,Hiraki K

更新日期：2014-07-29 00:00:00

abstract：:A new paradigm in neuroscience has recently emerged - the brain-gut axis (BGA). The contemporary focus in this paradigm has been gut → brain ("bottom-up"), in which the gut-microbiome, and its perturbations, affects one's psychological state-of-mind and behavior, and is pivotal in neurodegenerative disorders. The emer...

journal_title：Frontiers in neuroscience

authors： Isaiah S,Loots DT,Solomons R,van der Kuip M,Tutu Van Furth AM,Mason S

更新日期：2020-04-21 00:00:00

abstract：:Cryptotanshinone (CTN), a monomer compound extracted from the dried roots and rhizomes of Salvia miltiorrhiza Bge, has a variety of pharmacological effects. However, little research has been done on the mechanism of CTN in attenuating neuroinflammation. The present study aimed to investigate whether CTN can ameliorate...

journal_title：Frontiers in neuroscience

authors： Zhou Y,Wang X,Ying W,Wu D,Zhong P

更新日期：2019-08-21 00:00:00

abstract：:Various studies performed in cultured cells and in in vivo models of neuronal damage showed that cannabinoids exert a neuroprotective effect. The increase in cannabinoids and cannabinoid like substances after stroke has been postulated to limit the content of neuronal injury. As well-accepted, inflammation, and neuron...

journal_title：Frontiers in neuroscience

authors： Hohmann U,Pelzer M,Kleine J,Hohmann T,Ghadban C,Dehghani F

更新日期：2019-11-07 00:00:00

abstract：:Changing gait is crucial for adaptive and smooth animal locomotion. Although it remains unclear what makes animals decide on a specific gait, energy efficiency is an important factor. It has been reported that the relationship of oxygen consumption with speed is U-shaped for each horse gait and that different gaits ha...

journal_title：Frontiers in neuroscience

authors： Toeda M,Aoi S,Fujiki S,Funato T,Tsuchiya K,Yanagihara D

更新日期：2020-01-17 00:00:00

abstract：Objectives:Many post-traumatic patients with minimally conscious state are complicated by psychomotor inhibition state (PIS), which impedes further rehabilitation. The treatment of PIS is not satisfactory. This pilot study aimed to investigate effects of anodal transcranial direct current stimulation (A-tDCS) on PIS in...

journal_title：Frontiers in neuroscience

authors： Zhang X,Liu B,Li N,Li Y,Hou J,Duan G,Wu D

更新日期：2020-05-20 00:00:00

abstract：:In the brain, glucose homeostasis of extracellular fluid is crucial to the point that systems specifically dedicated to glucose sensing are found in areas involved in energy regulation and feeding behavior. Olfaction is a major sensory modality regulating food consumption. Nutritional status in turn modulates olfactor...

journal_title：Frontiers in neuroscience

authors： Al Koborssy D,Palouzier-Paulignan B,Salem R,Thevenet M,Romestaing C,Julliard AK

更新日期：2014-10-29 00:00:00

abstract：:Exosomes are involved in the progression of neurodegenerative diseases. The cellular prion protein (PrPC) is highly expressed on exosomes. In neurodegenerative diseases, PrPC has at least two functions: It is the substrate for the generation of pathological prion protein (PrPSc), a key player in the pathophysiology of...

journal_title：Frontiers in neuroscience

authors： Hartmann A,Muth C,Dabrowski O,Krasemann S,Glatzel M

更新日期：2017-04-19 00:00:00

abstract：:The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo, we surveyed genes related to m...

journal_title：Frontiers in neuroscience

authors： Knowlton WM,Hubert T,Wu Z,Chisholm AD,Jin Y

更新日期：2017-05-10 00:00:00

abstract：:Astrocytes are the most abundant type of glial cell in the central nervous system and perform a myriad of vital functions, however, the nature of their diversity remains a longstanding question in neuroscience. Using transcription factor motif discovery analysis on region-specific gene signatures from astrocytes we un...

journal_title：Frontiers in neuroscience

authors： Lozzi B,Huang TW,Sardar D,Huang AY,Deneen B

更新日期：2020-02-21 00:00:00

abstract：:The global prevalence of obesity has been steadily increasing. Although pharmacotherapy and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may lose long-term effectiveness. Obesity result largely from unbalanced energy homeostasis. Palatable and densely caloric foods may affect th...

journal_title：Frontiers in neuroscience

authors： Formolo DA,Gaspar JM,Melo HM,Eichwald T,Zepeda RJ,Latini A,Okun MS,Walz R

更新日期：2019-04-18 00:00:00

abstract：:This paper developed a cognitive task-load (CTL) classification algorithm and allocation strategy to sustain the optimal operator CTL levels over time in safety-critical human-machine integrated systems. An adaptive human-machine system is designed based on a non-linear dynamic CTL classifier, which maps a set of elec...

journal_title：Frontiers in neuroscience

authors： Zhang J,Yin Z,Wang R

更新日期：2017-03-17 00:00:00

abstract：:Here, we present the first description of an isolation syndrome in a patient who suffered prolonged cardiac arrest and underwent a standard therapeutic hypothermia protocol. Two years after the arrest, the patient demonstrated no motor responses to commands, communication capabilities, or visual tracking at the bedsid...

journal_title：Frontiers in neuroscience

authors： Forgacs PB,Fridman EA,Goldfine AM,Schiff ND

更新日期：2016-06-09 00:00:00

abstract：:HIGHLIGHTS Many AD target combinations are being explored for multi-target drug design.New databases and models increase the potential of computational drug designLiraglutide and other antidiabetics are strong candidates for repurposing to AD.Donecopride a dual 5-HT/AChE inhibitor shows promise in pre-clinical studies...

journal_title：Frontiers in neuroscience

authors： Hughes RE,Nikolic K,Ramsay RR

更新日期：2016-04-25 00:00:00

abstract：:The resting activity of the brain can be described by so-called intrinsic connectivity networks (ICNs), which consist of spatially and temporally distributed, but functionally connected, nodes. The coordinated activity of the resting state can be explored via magnetoencephalography (MEG) by studying frequency-dependen...

journal_title：Frontiers in neuroscience

authors： Dimitriadis SI,Routley B,Linden DE,Singh KD

更新日期：2018-08-03 00:00:00

abstract：:The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions. The purpose of the review is to take a comparative approach in the description of prolactin, its secretion from pituitary lactotrophs, and ...

journal_title：Frontiers in neuroscience

authors： Dobolyi A,Oláh S,Keller D,Kumari R,Fazekas EA,Csikós V,Renner É,Cservenák M

更新日期：2020-06-16 00:00:00

abstract：:Developing new standardized tools to characterize brain recording devices is critical to evaluate neural probes and for translation to clinical use. The signal-to-noise ratio (SNR) measurement is the gold standard for quantifying the performance of brain recording devices. Given the drawbacks with the SNR measure, our...

journal_title：Frontiers in neuroscience

authors： Suarez-Perez A,Gabriel G,Rebollo B,Illa X,Guimerà-Brunet A,Hernández-Ferrer J,Martínez MT,Villa R,Sanchez-Vives MV

更新日期：2018-11-29 00:00:00

abstract：:Alzheimer's disease (AD), a chronic multifactorial and complex neurodegenerative disorder is a leading cause of dementia. Recently, neuroinflammation has been hypothesized as a contributing factor to AD pathogenesis. The role of adaptive immune responses against neuronal antigens, which can either confer protection or...

journal_title：Frontiers in neuroscience

authors： Dhanwani R,Pham J,Premlal ALR,Frazier A,Kumar A,Pero ME,Bartolini F,Dutra JR,Marder KS,Peters B,Sulzer D,Sette A,Lindestam Arlehamn CS

更新日期：2020-08-27 00:00:00

abstract：:The central control of energy balance involves a highly regulated neuronal network within the hypothalamus and the dorsal vagal complex. In these structures, pro-opiomelanocortin (POMC) neurons are known to reduce meal size and to increase energy expenditure. In addition, leptin, a peripheral signal that relays inform...

journal_title：Frontiers in neuroscience

authors： Derghal A,Djelloul M,Trouslard J,Mounien L

更新日期：2017-04-05 00:00:00

abstract：:While adult neurogenesis is considered to be restricted to the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ), recent studies in humans and rodents provide evidence for newly generated neurons in regions generally considered as non-neurogenic, e.g., the striatum. Stimulating dopaminergic neurotransmi...

journal_title：Frontiers in neuroscience

authors： Salvi R,Steigleder T,Schlachetzki JC,Waldmann E,Schwab S,Winner B,Winkler J,Kohl Z

更新日期：2016-03-11 00:00:00

abstract：Purpose:The phantom sound of tinnitus is considered to be associated with abnormal functional coupling between the nucleus accumbens (NAc) and the prefrontal cortex, which may form a frontostriatal top-down gating system to evaluate and modulate sensory signals. Resting-state functional magnetic resonance imaging (fMRI...

journal_title：Frontiers in neuroscience

authors： Xu JJ,Cui J,Feng Y,Yong W,Chen H,Chen YC,Yin X,Wu Y

更新日期：2019-12-06 00:00:00

abstract：:The sliding-window-based dynamic functional connectivity networks (D-FCNs) derived from resting-state functional magnetic resonance imaging (rs-fMRI) are effective methods for diagnosing various neurological diseases, including autism spectrum disorder (ASD). However, traditional D-FCNs are low-order networks based on...

journal_title：Frontiers in neuroscience

authors： Zhao F,Chen Z,Rekik I,Lee SW,Shen D

更新日期：2020-04-28 00:00:00

abstract：:[This corrects the article on p. 589 in vol. 10, PMID: 28066172.]. ...

journal_title：Frontiers in neuroscience

authors： Wang H,Li X,Shan L,Zhu J,Chen R,Li Y,Yuan W,Yang L,Huang J

更新日期：2017-02-13 00:00:00

abstract：:Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These processes develop in parallel with general improvement of self-regulatory abilities, and performan...

journal_title：Frontiers in neuroscience

authors： Eichele H,Eichele T,Marquardt L,Adolfsdottir S,Hugdahl K,Sørensen L,Plessen KJ

更新日期：2017-06-12 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms throughout adult life in most of the affected patients. This unfavorable course is associated with multiple episodes and residual symptoms, mainly negative symptoms and cognitive deficits. The neural diathesis-stress model proposes that p...

journal_title：Frontiers in neuroscience

authors： Popovic D,Schmitt A,Kaurani L,Senner F,Papiol S,Malchow B,Fischer A,Schulze TG,Koutsouleris N,Falkai P

更新日期：2019-03-21 00:00:00

abstract：:Cognitive control of emotions depends on intermodular long-distance communications. However, negative connections between connector hubs are removed by traditional hard-thresholding approach in graph-theoretical research. Using soft-thresholding approach to reserve negative links, we explore time-varying features of c...

journal_title：Frontiers in neuroscience

authors： Zhang W,Chen J,Ren G,Tang F,Liu Q,Li H

更新日期：2019-10-25 00:00:00