Chronic Tinnitus Exhibits Bidirectional Functional Dysconnectivity in Frontostriatal Circuit.

abstract：:D-norpseudoephedrine (NPE), also known as cathine, is found naturally in the shrub Catha edulis "Khat." NPE has been widely used as an appetite suppressant for the treatment of obesity. Although it is known that NPE acts on α1-adrenergic receptors, there is little information about the role of dopamine receptors on NP...

journal_title：Frontiers in neuroscience

authors： Kalyanasundar B,Perez CI,Arroyo B,Moreno MG,Gutierrez R

更新日期：2020-10-16 00:00:00

abstract：:Environmental stressors including protein malnutrition (PMN) during pre-, neo- and post-natal age have been documented to affect cognitive development and cause increased susceptibility to neuropsychiatric disorders. Most studies have addressed either of the three windows and that does not emulate the clinical conditi...

journal_title：Frontiers in neuroscience

authors： Naik AA,Patro IK,Patro N

更新日期：2015-12-08 00:00:00

abstract：:Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These processes develop in parallel with general improvement of self-regulatory abilities, and performan...

journal_title：Frontiers in neuroscience

authors： Eichele H,Eichele T,Marquardt L,Adolfsdottir S,Hugdahl K,Sørensen L,Plessen KJ

更新日期：2017-06-12 00:00:00

abstract：:Value-based decision making relies on distributed neural systems that weigh the benefits of actions against the cost required to obtain a given outcome. Perturbations of these systems are thought to underlie abnormalities in action selection seen across many neuropsychiatric disorders. Genetic tools in mice provide a ...

journal_title：Frontiers in neuroscience

authors： Alabi OO,Fortunato MP,Fuccillo MV

更新日期：2019-02-07 00:00:00

abstract：:The Artificial Intelligence (AI) revolution foretold of during the 1960s is well underway in the second decade of the twenty first century. Its period of phenomenal growth likely lies ahead. AI-operated machines and technologies will extend the reach of Homo sapiens far beyond the biological constraints imposed by evo...

journal_title：Frontiers in neuroscience

authors： Krichmar JL,Severa W,Khan MS,Olds JL

更新日期：2019-06-27 00:00:00

abstract：:A coordinate transformation framework for understanding how neurons compute sensorimotor behaviors has generated significant advances toward our understanding of basic brain function. This influential scaffold focuses on neuronal encoding of spatial information represented in different coordinate systems (e.g., eye-ce...

journal_title：Frontiers in neuroscience

authors： Chang SW

更新日期：2013-08-21 00:00:00

abstract：:The autonomic nervous system (ANS) has a significant influence on the structural integrity and electrical conductivity of the atria. Aberrant activation of the sympathetic nervous system can induce heterogeneous changes with arrhythmogenic potential which can result in atrial tachycardia, atrial tachyarrhythmias and a...

journal_title：Frontiers in neuroscience

authors： Carnagarin R,Kiuchi MG,Ho JK,Matthews VB,Schlaich MP

更新日期：2019-01-23 00:00:00

abstract：:Dopamine system plays a pivotal role in specific kinds of substance use disorders (SUD, i. e., cocaine and methamphetamine use disorders). Many studies addressed whether dopamine-involved craving could be alleviated by non-invasive brain stimulation (NIBS) techniques. Nevertheless, the outcomes were highly inconsisten...

journal_title：Frontiers in neuroscience

authors： Ma T,Sun Y,Ku Y

更新日期：2019-10-18 00:00:00

abstract：:The dynamical systems view of movement generation in motor cortical areas has emerged as an effective way to explain the firing properties of populations of neurons recorded from these regions. Recently, many studies have focused on finding low-dimensional representations of these dynamical systems during voluntary re...

journal_title：Frontiers in neuroscience

authors： Xing D,Aghagolzadeh M,Truccolo W,Borton D

更新日期：2019-10-04 00:00:00

abstract：:Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy of HSA21 contributes to altered energy metabolism that appears to be a strong determinant in the development of...

journal_title：Frontiers in neuroscience

authors： Dierssen M,Fructuoso M,Martínez de Lagrán M,Perluigi M,Barone E

更新日期：2020-07-08 00:00:00

abstract：:The mechanisms by which glucocorticoids regulate food intake and resulting body mass in humans are not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on behavior contain important confounds. Here, we studied individua...

journal_title：Frontiers in neuroscience

authors： Moeller SJ,Couto L,Cohen V,Lalazar Y,Makotkine I,Williams N,Yehuda R,Goldstein RZ,Geer EB

更新日期：2016-02-05 00:00:00

abstract：Background:Non-invasive neuromodulation is an emerging therapy for children with early brain injury but is difficult to apply to preschoolers when windows of developmental plasticity are optimal. Transcranial static magnetic field stimulation (tSMS) decreases primary motor cortex (M1) excitability in adults but effects...

journal_title：Frontiers in neuroscience

authors： Hollis A,Zewdie E,Nettel-Aguirre A,Hilderley A,Kuo HC,Carlson HL,Kirton A

更新日期：2020-05-19 00:00:00

abstract：:Adapted exercise is an effective non-pharmacological tool to improve functional, cognitive, and psychological parameters in multiple sclerosis (MS), in association with increased quality of life (QoL) and decreased disease severity. Adipose tissue, through the production of different adipokines, is involved in regulat...

journal_title：Frontiers in neuroscience

authors： Grazioli E,Nigro E,Cerulli C,Borriello G,Mancini A,Tranchita E,Polito R,Parisi A,Buono P,Daniele A

更新日期：2020-12-22 00:00:00

abstract：:Protein tyrosine phosphatases (PTPs) are important regulators of intracellular signaling pathways via the dephosphorylation of phosphotyrosyl residues on various receptor and non-receptor substrates. The phosphorylation state of central nervous system (CNS) signaling components underlies the molecular mechanisms of a ...

journal_title：Frontiers in neuroscience

authors： Tsou RC,Bence KK

更新日期：2013-01-07 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public health concern that affects 69 million individuals each year worldwide. Neuropsychologists report that up to 40% of individuals undergoing evaluations for TBI may be malingering neurocognitive deficits for a compensatory reward. The memory recognition test of malingering ...

journal_title：Frontiers in neuroscience

authors： Neal J,Strothkamp S,Bedingar E,Cordero P,Wagner B,Vagnini V,Jiang Y

更新日期：2019-09-25 00:00:00

abstract：:Hearing loss can develop as a consequence of primary auditory neuron degeneration. These neurons are present within the spiral ganglion of the inner ear and co-exist with glial cells that assist in neuronal maintenance and function. There are limited interventions for individuals with hearing impairment, hence novel b...

journal_title：Frontiers in neuroscience

authors： Meas SJ,Nishimura K,Scheibinger M,Dabdoub A

更新日期：2018-11-13 00:00:00

abstract：:Resting-state functional magnetic resonance imaging (rs-fMRI) is a widely used technique for mapping the brain's functional architecture, so delineating the main sources of variance comprising the signal is crucial. Low frequency oscillations (LFO) that are not of neural origin, but which are driven by mechanisms rela...

journal_title：Frontiers in neuroscience

authors： Whittaker JR,Driver ID,Venzi M,Bright MG,Murphy K

更新日期：2019-05-07 00:00:00

abstract：:In patients with impaired liver function and hepatic encephalopathy (HE), consistent elevations of blood ammonia concentration suggest a crucial role in the pathogenesis of HE. Ammonia and acetate are metabolized in brain both primarily in astrocytes. Here, we used dynamic [(11)C]acetate PET of the brain to measure th...

journal_title：Frontiers in neuroscience

authors： Iversen P,Mouridsen K,Hansen MB,Jensen SB,Sørensen M,Bak LK,Waagepetersen HS,Schousboe A,Ott P,Vilstrup H,Keiding S,Gjedde A

更新日期：2014-11-03 00:00:00

abstract：:Developing new standardized tools to characterize brain recording devices is critical to evaluate neural probes and for translation to clinical use. The signal-to-noise ratio (SNR) measurement is the gold standard for quantifying the performance of brain recording devices. Given the drawbacks with the SNR measure, our...

journal_title：Frontiers in neuroscience

authors： Suarez-Perez A,Gabriel G,Rebollo B,Illa X,Guimerà-Brunet A,Hernández-Ferrer J,Martínez MT,Villa R,Sanchez-Vives MV

更新日期：2018-11-29 00:00:00

abstract：:Although the interplay between endogenous opioids and dopamine (DA) in the basal ganglia (BG) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. Vocal impairment is a common symptom of Parkinson's disease (PD), wherein DA depletion affects striosomes ri...

journal_title：Frontiers in neuroscience

authors： Kumar S,Mohapatra AN,Sharma HP,Singh UA,Kambi NA,Velpandian T,Rajan R,Iyengar S

更新日期：2019-07-03 00:00:00

abstract：:Animal functional magnetic resonance imaging (fMRI) has provided key insights into the physiological mechanisms underlying healthy and diseased brain states. In non-human primates, resting-state fMRI studies are commonly conducted under isoflurane anesthesia, where anesthetic concentration is used to roughly infer ane...

journal_title：Frontiers in neuroscience

authors： Zhang Z,Cai DC,Wang Z,Zeljic K,Wang Z,Wang Y

更新日期：2019-04-11 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:Thymoma is a tumor originating from thymic gland, frequently manifesting with paraneoplastic neurological disorders. Its association with paraneoplastic dysautonomia is relatively uncommon. Here, we describe the challenging case of a 71 year-old female who developed subacute autonomic failure with digestive pseudo-obs...

journal_title：Frontiers in neuroscience

authors： Ricigliano VAG,Fossati B,Saraceno L,Cavalli M,Bazzigaluppi E,Meola G

更新日期：2018-01-24 00:00:00

abstract：:Learning a new language requires the use of extensive neural networks and can represent a powerful tool to reorganize brain neuroplasticity. In this study, we analyze how a 4 months long second language learning program (16, 2 h sessions) can lead to functional changes in the brain of healthy elderly individuals. A la...

journal_title：Frontiers in neuroscience

authors： Bubbico G,Chiacchiaretta P,Parenti M,di Marco M,Panara V,Sepede G,Ferretti A,Perrucci MG

更新日期：2019-05-15 00:00:00

abstract：:Sensory information can interact to impact perception and behavior. Foods are appreciated according to their appearance, smell, taste and texture. Athletes and dancers combine visual, auditory, and somatosensory information to coordinate their movements. Under laboratory settings, detection and discrimination are like...

journal_title：Frontiers in neuroscience

authors： Sperdin HF,Cappe C,Murray MM

更新日期：2010-05-15 00:00:00

abstract：:Circadian rhythms of behavior and physiology are generated by central and peripheral circadian oscillators entrained by periodic environmental or physiological stimuli. A master circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) is directly entrained by daily light-dark (LD) cycles, and coordinates ...

journal_title：Frontiers in neuroscience

authors： Patton DF,Mistlberger RE

更新日期：2013-10-14 00:00:00

abstract：:We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI). Sparse gro...

journal_title：Frontiers in neuroscience

authors： Kohannim O,Hibar DP,Stein JL,Jahanshad N,Hua X,Rajagopalan P,Toga AW,Jack CR Jr,Weiner MW,de Zubicaray GI,McMahon KL,Hansell NK,Martin NG,Wright MJ,Thompson PM,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2012-08-06 00:00:00

abstract：:The blood-brain barrier (BBB) mediates the communication between the periphery and the central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play a role in neurodegenerative disease. This has stimulated a wealth of information on the molecular impact of insulin in the brain, particularl...

journal_title：Frontiers in neuroscience

authors： Rhea EM,Banks WA

更新日期：2019-06-04 00:00:00

abstract：:Diffusion magnetic resonance imaging (dMRI) is a compelling tool for investigating the structure and geometry of brain tissue based on indirect measurement of the diffusion anisotropy of water. Recent developments in global top-down tractogram optimizations enable the estimation of streamline weights, which characteri...

journal_title：Frontiers in neuroscience

authors： Sommer S,Kozerke S,Seifritz E,Staempfli P

更新日期：2017-12-22 00:00:00

abstract：Objective:To evaluate the effects of long-term High-definition transcranial direct current stimulation (HD-tDCS) over precuneus on the level of consciousness (LOC) and the relationship between Mismatch negativity (MMN) and the LOC over the therapy period in patients with Disorders of consciousness (DOCs). Methods:We e...

journal_title：Frontiers in neuroscience

authors： Wang X,Guo Y,Zhang Y,Li J,Gao Z,Li Y,Zhou T,Zhang H,He J,Cong F

更新日期：2020-04-28 00:00:00