Using clinicopathological analysis of general practitioner skin surgery to determine educational requirements and guidelines.

abstract：OBJECTIVES:To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN:Screening is offered on the basis of informed consent in response to an information sheet entitled "A new test for baby boys--Do you want it?" The programme includes a prospective long term evaluation of family res...

journal_title：BMJ (Clinical research ed.)

authors： Bradley DM,Parsons EP,Clarke AJ

更新日期：1993-02-06 00:00:00

abstract：OBJECTIVE:To assess the efficacy of high serum cholesterol concentration, raised blood pressure, and smoking as predictors of coronary heart disease. DESIGN:Prospective cohort study of middle aged men conducted over 25 years. SETTING:Finish components of an ongoing international study (seven countries study). PARTIC...

journal_title：BMJ (Clinical research ed.)

authors： Pekkanen J,Nissinen A,Puska P,Punsar S,Karvonen MJ

更新日期：1989-07-08 00:00:00

abstract：OBJECTIVES:To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases of SARS. DESIGN:Prospective observational study. SETTING:A newly set up SARS screening clinic in the emergency departm...

journal_title：BMJ (Clinical research ed.)

authors： Rainer TH,Cameron PA,Smit D,Ong KL,Hung AN,Nin DC,Ahuja AT,Si LC,Sung JJ

更新日期：2003-06-21 00:00:00

abstract：OBJECTIVE:To determine the outcome of administration of neuroleptics to patients with senile dementia of Lewy body type confirmed at necropsy. DESIGN:Retrospective analysis of clinical notes blind to neuropathological diagnosis. SETTING:Specialist psychogeriatric assessment units referring cases for necropsy to a tea...

journal_title：BMJ (Clinical research ed.)

authors： McKeith I,Fairbairn A,Perry R,Thompson P,Perry E

更新日期：1992-09-19 00:00:00

abstract：OBJECTIVE:To determine the effects on independence in older people needing rehabilitation in a locality based community hospital compared with care on a ward for elderly people in a district general hospital. DESIGN:Randomised controlled trial. SETTING:Care in a community hospital and district general hospital in Bra...

journal_title：BMJ (Clinical research ed.)

authors： Green J,Young J,Forster A,Mallinder K,Bogle S,Lowson K,Small N

更新日期：2005-08-06 00:00:00

abstract：:In most European countries health has been shown to be linked to social circumstances--gradients in health status have persisted for decades, despite major changes in the principal causes of death. In central and eastern Europe life expectancy has stagnated since the mid-60s, whereas in the West it has increased; but ...

journal_title：BMJ (Clinical research ed.)

authors： Power C

更新日期：1994-04-30 00:00:00

abstract：OBJECTIVE:To determine if trimethoprim use for urinary tract infection (UTI) is associated with an increased risk of acute kidney injury, hyperkalaemia, or sudden death in the general population. DESIGN:Cohort study. SETTING:UK electronic primary care records from practices contributing to the Clinical Practice Resea...

journal_title：BMJ (Clinical research ed.)

authors： Crellin E,Mansfield KE,Leyrat C,Nitsch D,Douglas IJ,Root A,Williamson E,Smeeth L,Tomlinson LA

更新日期：2018-02-09 00:00:00

abstract：:Accumulating data indicate that modifications in diet may reduce the risk of cancer by as much as one third and possibly by as much as two thirds. On the basis of the existing evidence, however, it is not possible to be certain which cancers are causally related to diet and what proportion of them are due to specific ...

journal_title：BMJ (Clinical research ed.)

authors： Austoker J

更新日期：1994-06-18 00:00:00

abstract：OBJECTIVE:To analyse the relation between treated blood pressure and concomitant risk factor and morbidity from acute myocardial infarction. DESIGN:Prospective longitudinal study. Treated blood pressures and other variables were used to predict acute myocardial infarction. SETTING:Primary health care in Skaraborg, Sw...

journal_title：BMJ (Clinical research ed.)

authors： Lindblad U,Råstam L,Rydén L,Ranstam J,Isacsson SO,Berglund G

更新日期：1994-03-12 00:00:00

abstract：OBJECTIVES:To observe one general practice's attempt to reduce prescribing costs on becoming third wave fundholders through the introduction of a generic formulary applied to all new and repeat prescribing. To assess the impact on patients and prescribing patterns. DESIGN:An observational study using interviews with p...

journal_title：BMJ (Clinical research ed.)

authors： Dowell JS,Snadden D,Dunbar JA

更新日期：1995-02-25 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intensive geriatric rehabilitation on demented patients with hip fracture. DESIGN:Preplanned subanalysis of randomised intervention study. Settting: Jyväskylä Central Hospital, Finland. PARTICIPANTS:243 independently living patients aged 65 years or older admitted to hospital with ...

journal_title：BMJ (Clinical research ed.)

authors： Huusko TM,Karppi P,Avikainen V,Kautiainen H,Sulkava R

更新日期：2000-11-04 00:00:00

abstract：:The instrument through which a commissioner purchases health services from a provider is, as in other walks of life, a contract, so considerable importance has been attached by the NHS Executive to the contracting mechanism. A contract should in theory influence the quality of the service provided, but they are in man...

journal_title：BMJ (Clinical research ed.)

authors： Hopkins A,Solomon JK

更新日期：1996-08-24 00:00:00

abstract：OBJECTIVES:To examine the incidence of suicides due to co-proxamol compared with tricyclic antidepressants and paracetamol, and to compare fatality rates for self poisonings with these drugs. DESIGN:Analysis of routinely collected national and local data on suicides and self poisonings. SETTING:Records of suicides in...

journal_title：BMJ (Clinical research ed.)

authors： Hawton K,Simkin S,Deeks J

更新日期：2003-05-10 00:00:00

abstract：OBJECTIVE:To determine if the macrolide clarithromycin affects mortality and cardiovascular morbidity in patients with stable coronary heart disease. DESIGN:Centrally randomised multicentre trial. All parties at all stages were blinded. Analyses were by intention to treat. SETTING:Five Copenhagen University cardiolog...

journal_title：BMJ (Clinical research ed.)

authors： Jespersen CM,Als-Nielsen B,Damgaard M,Hansen JF,Hansen S,Helø OH,Hildebrandt P,Hilden J,Jensen GB,Kastrup J,Kolmos HJ,Kjøller E,Lind I,Nielsen H,Petersen L,Gluud C,CLARICOR Trial Group.

更新日期：2006-01-07 00:00:00

abstract：OBJECTIVE:To investigate a reported association between dental disease and risk of coronary heart disease. SETTING:National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN:Prospective cohort study in which participants underwent a standard dental examination at bas...

journal_title：BMJ (Clinical research ed.)

authors： DeStefano F,Anda RF,Kahn HS,Williamson DF,Russell CM

更新日期：1993-03-13 00:00:00

abstract：OBJECTIVE:To examine variations in teenage pregnancy rates in Trent region and to determine possible associations with local general practice characteristics such as the age and sex of the doctors. DESIGN:Cross sectional survey. SETTING:All 826 general practices in Trent region in existence between 1994 and 1997. SU...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Allen J,Pringle M,Ebdon D,McPhearson M,Churchill D,Bradley S

更新日期：2000-03-25 00:00:00

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：OBJECTIVE:To examine the associations of a vegetarian diet and dietary fibre intake with risk of diverticular disease. DESIGN:Prospective cohort study. SETTING:The EPIC-Oxford study, a cohort of mainly health conscious participants recruited from around the United Kingdom. PARTICIPANTS:47,033 men and women living in...

journal_title：BMJ (Clinical research ed.)

authors： Crowe FL,Appleby PN,Allen NE,Key TJ

更新日期：2011-07-19 00:00:00

abstract：OBJECTIVES:To determine whether informed consent introduces selection bias in prospective observational studies using data from medical records, and consent rates for such studies. DESIGN:Systematic review. DATA SOURCES:Embase, Medline, and the Cochrane Library up to March 2008, reference lists from pertinent article...

journal_title：BMJ (Clinical research ed.)

authors： Kho ME,Duffett M,Willison DJ,Cook DJ,Brouwers MC

更新日期：2009-03-12 00:00:00

abstract：OBJECTIVE:To examine the protective efficacy of measles vaccination in infants in a low income country before 9 months of age. DESIGN:Randomised clinical trial. PARTICIPANTS:1333 infants aged 4.5 months: 441 in treatment group and 892 in control group. SETTING:Urban area in Guinea-Bissau. INTERVENTION:Measles vacci...

journal_title：BMJ (Clinical research ed.)

authors： Martins CL,Garly ML,Balé C,Rodrigues A,Ravn H,Whittle HC,Lisse IM,Aaby P

更新日期：2008-07-24 00:00:00

abstract：OBJECTIVE:To determine the prevalence of diabetes in relation to birth weight in Pima Indians. DESIGN:Follow up study of infants born during 1940-72 who had undergone a glucose tolerance test at ages 20-39 years. SETTING:Gila River Indian community, Arizona. SUBJECTS:1179 American Indians. MAIN OUTCOME MEASURE:Prev...

journal_title：BMJ (Clinical research ed.)

authors： McCance DR,Pettitt DJ,Hanson RL,Jacobsson LT,Knowler WC,Bennett PH

更新日期：1994-04-09 00:00:00

abstract：OBJECTIVE:To evaluate participants' perceptions of the impact on them of an additional six months' training beyond the standard 12 month general practice vocational training scheme. DESIGN:Qualitative study using focus groups. SETTING:General practice vocational training in Northern Ireland. PARTICIPANTS:13 general ...

journal_title：BMJ (Clinical research ed.)

authors： Sibbett CH,Thompson WT,Crawford M,McKnight A

更新日期：2003-10-25 00:00:00

abstract：OBJECTIVE:To describe risk factors for infantile colic. DESIGN:Questionnaire administered by health visitors. SETTING:Sheffield. SUBJECTS:Mothers of 76,747 infants born between 1 August 1975 and 31 May 1988, interviewed when the infant was 1 month old. MAIN OUTCOME MEASURES:Reporting of infantile colic and its dura...

journal_title：BMJ (Clinical research ed.)

authors： Crowcroft NS,Strachan DP

更新日期：1997-05-03 00:00:00

abstract：OBJECTIVE:To determine whether patients with unexpected prehospital cardiac arrest could be identified in whom ambulance resuscitation attempts would be futile. DESIGN:Review of ambulance and hospital records; detailed review of automated external defibrillator rhythm strips of patients in whom no shock was advised. ...

journal_title：BMJ (Clinical research ed.)

authors： Marsden AK,Ng GA,Dalziel K,Cobbe SM

更新日期：1995-07-01 00:00:00

abstract：AIM:To compare perinatal morbidity and mortality for babies delivered in water with rates for babies delivered conventionally (not in water). DESIGN:Surveillance study (of all consultant paediatricians) and postal survey (of all NHS maternity units). SETTING:British Isles (surveillance study); England and Wales (post...

journal_title：BMJ (Clinical research ed.)

authors： Gilbert RE,Tookey PA

更新日期：1999-08-21 00:00:00

abstract：OBJECTIVES:To investigate whether routinely collected data from hospital episode statistics could be used to identify the gynaecologist Rodney Ledward, who was suspended in 1966 and was the subject of the Ritchie inquiry into quality and practice within the NHS. DESIGN:A mixed scanning approach was used to identify se...

journal_title：BMJ (Clinical research ed.)

authors： Harley M,Mohammed MA,Hussain S,Yates J,Almasri A

更新日期：2005-04-23 00:00:00

abstract：:Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome (HHS) are life threatening complications that occur in patients with diabetes. In addition to timely identification of the precipitating cause, the first step in acute management of these disorders includes aggressive administration of intravenous fluids wi...

journal_title：BMJ (Clinical research ed.)

authors： Karslioglu French E,Donihi AC,Korytkowski MT

更新日期：2019-05-29 00:00:00

abstract：:The identification of the gene for cystic fibrosis has led to the possibility of population based screening for carriers of cystic fibrosis to identify couples at risk of having an affected child. Pilot studies have shown that screening is feasible and does not cause untoward anxiety, though the uptake of testing vari...

journal_title：BMJ (Clinical research ed.)

authors： Modell M

更新日期：1993-10-02 00:00:00

abstract：:Robots designed for surgery have three main advantages over humans. They have greater three dimensional spatial accuracy, are more reliable, and can achieve much greater precision. Although few surgical robots are yet in clinical trials one or two have advanced to the stage of seeking approval from the UK's Medical De...

journal_title：BMJ (Clinical research ed.)

authors： Buckingham RA,Buckingham RO

更新日期：1995-12-02 00:00:00

abstract：OBJECTIVES:To measure, in a service setting, the effect of magnetic resonance imaging on diagnosis, diagnostic certainty, and patient management in the neurosciences; to measure the cost per patient scanned; to estimate the marginal cost of imaging and compare this with its diagnostic impact; to measure changes in pati...

journal_title：BMJ (Clinical research ed.)

authors： Szczepura AK,Fletcher J,Fitz-Patrick JD

更新日期：1991-12-07 00:00:00