Diet and cancer.

abstract：:A study was conducted to investigate a novel approach to the prophylaxis of schizophrenic relapse. The treatment strategy comprised brief intermittent courses of neuroleptic agents begun as soon as non-psychotic symptoms believed to be early signs of relapse appeared. Fifty four stable, remitted outpatients meeting th...

journal_title：BMJ (Clinical research ed.)

authors： Jolley AG,Hirsch SR,McRink A,Manchanda R

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVES:To estimate the cost effectiveness of statins in lowering serum cholesterol concentration in people at varying risk of fatal cardiovascular disease and to explore the implications of changing the criteria for intervention on cost and cost effectiveness for a purchasing authority. DESIGN:A life table method ...

journal_title：BMJ (Clinical research ed.)

authors： Pharoah PD,Hollingworth W

更新日期：1996-06-08 00:00:00

abstract：OBJECTIVE:To explore geographical and sociodemographic factors associated with variation in equity in access to total hip and knee replacement surgery. DESIGN:Combining small area estimates of need and provision to explore equity in access to care. SETTING:English census wards. SUBJECTS:Patients throughout England w...

journal_title：BMJ (Clinical research ed.)

authors： Judge A,Welton NJ,Sandhu J,Ben-Shlomo Y

更新日期：2010-08-11 00:00:00

abstract：OBJECTIVE:To assess the safety and effectiveness of eflornithine as first line treatment for human African trypanosomiasis. DESIGN:Cohort study. SETTING:Control programme in Ibba, southern Sudan. PARTICIPANTS:1055 adults and children newly diagnosed with second stage disease in a 16 month period. MAIN OUTCOME MEASU...

journal_title：BMJ (Clinical research ed.)

authors： Priotto G,Pinoges L,Fursa IB,Burke B,Nicolay N,Grillet G,Hewison C,Balasegaram M

更新日期：2008-03-29 00:00:00

abstract：OBJECTIVE:To identify the attitudes of general practitioners towards the use of thermometers in general practice. DESIGN:Postal questionnaire survey. SETTING:All general practitioners in the catchment area of Frimley Park Hospital, Surrey. SUBJECTS:145 general practitioners. MAIN OUTCOME MEASURES:Answers to questio...

journal_title：BMJ (Clinical research ed.)

authors： Clarke S

更新日期：1992-04-11 00:00:00

abstract：OBJECTIVES:To determine the strength of evidence for the effectiveness of mental health interventions for patients with three common somatic conditions (chronic fatigue syndrome, irritable bowel syndrome, and chronic back pain). To assess whether results obtained in secondary care can be extrapolated to primary care an...

journal_title：BMJ (Clinical research ed.)

authors： Raine R,Haines A,Sensky T,Hutchings A,Larkin K,Black N

更新日期：2002-11-09 00:00:00

abstract：OBJECTIVE:To obtain data on sexual contact between doctors and their patients. DESIGN:Anonymous questionnaire with 17 items sent to all working gynaecologists (n = 595) and all ear, nose, and throat specialists (n = 380) in the Netherlands. RESULTS:Response rate was 74%; a total 64 doctors gave a reason for not compl...

journal_title：BMJ (Clinical research ed.)

authors： Wilbers D,Veenstra G,van de Wiel HB,Weijmar Schultz WC

更新日期：1992-06-13 00:00:00

abstract：OBJECTIVE:To determine prevalence of HIV infection and drug injecting behaviour among inmates of Glenochil Prison on a specified date a year after an outbreak of hepatitis B and HIV infection. DESIGN:Cross sectional: voluntary, anonymous HIV salivary antibody surveillance and linked self completion questionnaire on ri...

journal_title：BMJ (Clinical research ed.)

authors： Gore SM,Bird AG,Burns SM,Goldberg DJ,Ross AJ,Macgregor J

更新日期：1995-02-04 00:00:00

abstract：:The aim of the study was to determine the outcome in 181 diabetic patients with advanced, previously untreated renal impairment who had been identified in a survey conducted in six health regions in the United Kingdom in 1985. Late in 1987 questionnaires were sent to the consultant physicians, geriatricians, and nephr...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1989-11-04 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. DESIGN:Prospective cohort study. SETTING:28 hospitals in the Netherlands and Belgium. PARTICIPANTS:1920 consecutive women treated with toc...

journal_title：BMJ (Clinical research ed.)

authors： de Heus R,Mol BW,Erwich JJ,van Geijn HP,Gyselaers WJ,Hanssens M,Härmark L,van Holsbeke CD,Duvekot JJ,Schobben FF,Wolf H,Visser GH

更新日期：2009-03-05 00:00:00

abstract：OBJECTIVES:To assess the incidence, time of day, and driver morbidity associated with vehicle accidents where the most likely cause was the driver falling asleep at the wheel. DESIGN:Two surveys were undertaken, in southwest England and the midlands, by using police databases or on the spot interviews. SUBJECTS:Drive...

journal_title：BMJ (Clinical research ed.)

authors： Horne JA,Reyner LA

更新日期：1995-03-04 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE:To quantify and compare the contribution of 306 diseases and injuries to the changes in health adjusted life expectancy at birth (HALE0) between 1990 and 2013. DESIGN:Retrospective demographic analysis based on aggregated data and using life table technique, Sullivan method, and decomposition method for diff...

journal_title：BMJ (Clinical research ed.)

authors： Chen H,Chen G,Zheng X,Guo Y

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVES:To evaluate the cost effectiveness of human papillomavirus testing after treatment for cervical intraepithelial neoplasia (CIN). DESIGN:Economic analysis using a Markov modelling approach to combine cost and epidemiological data from the NHS Sentinel Sites Study with data from previous studies of post-treat...

journal_title：BMJ (Clinical research ed.)

authors： Legood R,Smith M,Lew JB,Walker R,Moss S,Kitchener H,Patnick J,Canfell K

更新日期：2012-10-31 00:00:00

abstract：:The studies reviewed here show that the duration and severity of individual episodes of back pain can be lessened, reducing recurrences and their cost in terms of suffering and lost work. Frank examines differential diagnosis; acute, chronic, and intractable pain; and service implications. Modern management emphasises...

journal_title：BMJ (Clinical research ed.)

authors： Frank A

更新日期：1993-04-03 00:00:00

abstract：OBJECTIVE:To assess oesophageal Doppler ultrasonography as a convenient means of optimising positive end expiratory pressure for maximal delivery of oxygen to tissues. DESIGN:Measurements of blood flow, arterial oxygen saturation, and cardiac output by thermodilution (when available) at baseline and at 20-30 minutes a...

journal_title：BMJ (Clinical research ed.)

authors： Singer M,Bennett D

更新日期：1989-05-20 00:00:00

abstract：OBJECTIVES:To investigate whether the use of graduated compression stockings (GCS) offers any adjuvant benefit when pharmaco-thromboprophylaxis is used for venous thromboembolism prophylaxis in patients undergoing elective surgery. DESIGN:Open, multicentre, randomised, controlled, non-inferiority trial. SETTING:Seven...

journal_title：BMJ (Clinical research ed.)

authors： Shalhoub J,Lawton R,Hudson J,Baker C,Bradbury A,Dhillon K,Everington T,Gohel MS,Hamady Z,Hunt BJ,Stansby G,Warwick D,Norrie J,Davies AH,GAPS trial investigators.

更新日期：2020-05-13 00:00:00

abstract：:Objectives To estimate small for gestational age birth prevalence and attributable neonatal mortality in low and middle income countries with the INTERGROWTH-21st birth weight standard.Design Secondary analysis of data from the Child Health Epidemiology Reference Group (CHERG), including 14 birth cohorts with gestatio...

journal_title：BMJ (Clinical research ed.)

authors： Lee AC,Kozuki N,Cousens S,Stevens GA,Blencowe H,Silveira MF,Sania A,Rosen HE,Schmiegelow C,Adair LS,Baqui AH,Barros FC,Bhutta ZA,Caulfield LE,Christian P,Clarke SE,Fawzi W,Gonzalez R,Humphrey J,Huybregts L,Kariuki

更新日期：2017-08-17 00:00:00

abstract：:According to a London physician, women with epilepsy taking antiepileptic drugs can take combined oral contraceptives (OCs). It is usual to recommend a combined OC preparation containing at least 50 mcg of estrogen (Ovran) from patients taking enzyme-inducing antiepileptic drugs; this can be increased to 60 mcg by ta...

journal_title：BMJ (Clinical research ed.)

authors： O'Brien MD,Gilmour-White S

更新日期：1993-08-21 00:00:00

abstract：:Objective To improve the selection of patients with acute ischaemic stroke for intra-arterial treatment using a clinical decision tool to predict individual treatment benefit.Design Multivariable regression modelling with data from two randomised controlled clinical trials.Setting 16 hospitals in the Netherlands (deri...

journal_title：BMJ (Clinical research ed.)

authors： Venema E,Mulder MJHL,Roozenbeek B,Broderick JP,Yeatts SD,Khatri P,Berkhemer OA,Emmer BJ,Roos YBWEM,Majoie CBLM,van Oostenbrugge RJ,van Zwam WH,van der Lugt A,Steyerberg EW,Dippel DWJ,Lingsma HF

更新日期：2017-05-03 00:00:00

abstract：OBJECTIVE:To investigate the association between treatment induced change in high density lipoprotein cholesterol and total death, coronary heart disease death, and coronary heart disease events (coronary heart disease death and non-fatal myocardial infarction) adjusted for changes in low density lipoprotein cholestero...

journal_title：BMJ (Clinical research ed.)

authors： Briel M,Ferreira-Gonzalez I,You JJ,Karanicolas PJ,Akl EA,Wu P,Blechacz B,Bassler D,Wei X,Sharman A,Whitt I,Alves da Silva S,Khalid Z,Nordmann AJ,Zhou Q,Walter SD,Vale N,Bhatnagar N,O'Regan C,Mills EJ,Bucher HC,M

更新日期：2009-02-16 00:00:00

abstract：OBJECTIVES:To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. DESIGN:Multicentre, open label, three arm, parallel group, ran...

journal_title：BMJ (Clinical research ed.)

authors： Bensdorp AJ,Tjon-Kon-Fat RI,Bossuyt PM,Koks CA,Oosterhuis GJ,Hoek A,Hompes PG,Broekmans FJ,Verhoeve HR,de Bruin JP,van Golde R,Repping S,Cohlen BJ,Lambers MD,van Bommel PF,Slappendel E,Perquin D,Smeenk JM,Pelinck MJ,

更新日期：2015-01-09 00:00:00

abstract：:In order to determine whether the loss in bone density seen in users of depot medroxyprogesterone acetate is reversible, a comparative study was undertaken in three groups of women. Group 1 consisted of 14 women who had used the contraceptive for at least 3 years and then discontinued use. Group 2 was 22 longterm us...

journal_title：BMJ (Clinical research ed.)

authors： Cundy T,Cornish J,Evans MC,Roberts H,Reid IR

更新日期：1994-01-22 00:00:00

abstract：OBJECTIVES:To examine the association of plasma caffeine concentrations during pregnancy with fetal growth and to compare this with relations with reported caffeine intake. DESIGN:Prospective population based study. SETTING:District general hospital, inner London. SUBJECTS:Women booking for delivery between 1982 and...

journal_title：BMJ (Clinical research ed.)

authors： Cook DG,Peacock JL,Feyerabend C,Carey IM,Jarvis MJ,Anderson HR,Bland JM

更新日期：1996-11-30 00:00:00

abstract：:Objective To determine whether educational attainment is a causal risk factor in the development of coronary heart disease.Design Mendelian randomisation study, using genetic data as proxies for education to minimise confounding.Setting The main analysis used genetic data from two large consortia (CARDIoGRAMplusC4D an...

journal_title：BMJ (Clinical research ed.)

authors： Tillmann T,Vaucher J,Okbay A,Pikhart H,Peasey A,Kubinova R,Pajak A,Tamosiunas A,Malyutina S,Hartwig FP,Fischer K,Veronesi G,Palmer T,Bowden J,Davey Smith G,Bobak M,Holmes MV

更新日期：2017-08-30 00:00:00

abstract：OBJECTIVES:To understand the approaches to learning of practising physicians in their workplace and to assess the relation of these approaches to their motivation for, preferred methods of, and perceived barriers to continuing medical education. DESIGN:Postal survey of 800 Ontario physicians. PARTICIPANTS:373 physici...

journal_title：BMJ (Clinical research ed.)

authors： Delva MD,Kirby JR,Knapper CK,Birtwhistle RV

更新日期：2002-11-23 00:00:00

abstract：OBJECTIVE:To determine whether inhaled salmeterol, a new long acting inhaled beta adrenergic agonist, reduces nocturnal bronchoconstriction and improves sleep quality in patients with nocturnal asthma. DESIGN:Randomised, double blind, placebo controlled crossover study. SETTING:Hospital outpatient clinics in Edinburg...

journal_title：BMJ (Clinical research ed.)

authors： Fitzpatrick MF,Mackay T,Driver H,Douglas NJ

更新日期：1990-12-15 00:00:00

abstract：:The World Health Organization's (WHO) definition of health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity" had the merit of widening concepts of health to include psychological and social aspects, but is of no practical use. In fact, this statement m...

journal_title：BMJ (Clinical research ed.)

authors： Saracci R

更新日期：1997-05-10 00:00:00

abstract：:The import of the HIV or AIDS epidemic for heterosexuals in Britain is difficult to evaluate at this stage. By June 1988, only 60 cases of heterosexually acquired AIDS are known, out of 1598 reported AIDS cases. Of these, only 6 women and 4 men presumably were infected in Britain, the rest abroad. But, judging from...

journal_title：BMJ (Clinical research ed.)

authors： Skegg DC

更新日期：1989-02-18 00:00:00