A retrospective review of the frequency and nature of acute hypersensitivity reactions at a medium-sized infusion center: comparison to reported values and inconsistencies found in literature.

abstract：PURPOSE:We conducted a meta-analysis to evaluate and compare the short- and long-term results of laparoscopy-assisted colectomy (LAC) and open colectomy (OC) for colon cancer. METHODS:We searched MEDLINE, EMBASE, Science Citation Index, and Cochrane Controlled Trial Register for relevant papers published between Janua...

journal_title：Journal of Cancer

authors： Ohtani H,Tamamori Y,Arimoto Y,Nishiguchi Y,Maeda K,Hirakawa K

更新日期：2012-01-01 00:00:00

abstract：:Amplified in breast cancer 1 (AIB1) gene, a coactivator for steroid receptor, is frequently amplified in diverse cancers and is considered as an oncogene in tumorigenesis. However, the prognostic significance of AIB1 amplification in gliomas remains totally unclear. In this study, 115 gliomas and 16 benign meningiomas...

journal_title：Journal of Cancer

authors： Chen L,Wang C,Zhang X,Gao K,Liu R,Shi B,Hou P

更新日期：2016-10-22 00:00:00

abstract：:Endocrine resistance in hormone receptor positive breast cancer patients urges us to develop novel approaches such as inhibitors of the cyclin-dependent kinases (CDK) 4/6 to reverse its resistance. Nowadays, three selective CDK4/6 inhibitors (Palbociclib, Ribociclib and Abemaciclib) are approved by Federal Drug Admini...

journal_title：Journal of Cancer

authors： Chen X,Xu D,Li X,Zhang J,Xu W,Hou J,Zhang W,Tang J

更新日期：2019-10-21 00:00:00

abstract：PURPOSE:Urothelial carcinoma (UC) is a type of tumor, especially of the urinary bladder, that affects people worldwide. Clarification of its detailed tumor biology and discovery of potential targets for developing treatment strategies are imperative because of frequent recurrences and poor prognosis of advanced UCs. By...

journal_title：Journal of Cancer

authors： Chang IW,Li CF,Lin VC,He HL,Liang PI,Wu WJ,Li CC,Huang CN

更新日期：2016-07-08 00:00:00

abstract：:Aim: BAP1 is frequently mutated in clear cell renal cell carcinoma (ccRCC) with a definitive role still unclear. Methods: In silico analysis of BAP1-mutant and wild-type gene enrichment and functional annotation in TCGA-KIRC dataset was performed. Target gene was studied based on functional clustering and was knowledg...

journal_title：Journal of Cancer

authors： Sun C,Zhao C,Li S,Wang J,Zhou Q,Sun J,Ding Q,Liu M,Ding G

更新日期：2018-10-01 00:00:00

abstract：:The INT0116 trial was a milestone study and laid the foundation for the adjuvant radiotherapy (RT) associated to concurrent chemotherapy (CT) for the treatment of gastric cancer (GC) after gastrectomy. However, it is still controversial whether adding RT to CT could further benefit D2-dissected GC patients. The ARTIST...

journal_title：Journal of Cancer

authors： Xu J,Zhu J,Wei Q

更新日期：2019-01-01 00:00:00

abstract：:Background: Immunotherapy including immune checkpoint blockade, cancer vaccines, and adoptive cell therapy. However, no immune therapies support ovarian cancer. It is not clear whether the neutrophils, the component of the immune system derived from umbilical cord blood play a role in inhibiting the progression of ova...

journal_title：Journal of Cancer

authors： Liu Q,Yang W,Luo N,Liu J,Wu Y,Ding J,Li C,Cheng Z

更新日期：2020-05-18 00:00:00

abstract：:Tripartite motif-containing 67 (TRIM67), an E3 ubiquitin ligase, belongs to the TRIM protein family. The relationship between TRIM67 and tumorigenesis is not fully clear. Here, we elucidated TRIM67 function in non-small cell lung cancer (NSCLC). TRIM67 immunostaining results were correlated with clinicopathological fe...

journal_title：Journal of Cancer

authors： Jiang J,Ren H,Xu Y,Wudu M,Wang Q,Liu Z,Su H,Jiang X,Zhang Y,Zhang B,Qiu X

更新日期：2020-01-01 00:00:00

abstract：:Background: Whether metastasectomy improves prognosis of gastric cancer patients with ovarian metastases (Krukenberg tumors) is not clear. In this study, we examined the survival benefit of metastasectomy combined with chemotherapy for treatment of synchronous Krukenberg tumors from gastric cancer and identified the p...

journal_title：Journal of Cancer

authors： Yan D,Du Y,Dai G,Huang L,Xu Q,Yu P

更新日期：2018-10-20 00:00:00

abstract：INTRODUCTION:Bioimpedance is a measure of the electrical properties of biological tissues. In the last two decades bioimpedance has been successfully introduced in clinical diagnosis of cancer. It has been demonstrated that tumoral tissues often show lower bioimpedance values than healthy tissues. The aim of this work ...

journal_title：Journal of Cancer

authors： Tatullo M,Marrelli M,Amantea M,Paduano F,Santacroce L,Gentile S,Scacco S

更新日期：2015-08-20 00:00:00

abstract：:Hepatocellular Carcinoma is a major healthcare problem, representing the third most common cause of cancer-related mortality worldwide. There are 130 million Hepatitis C virus infected patients worldwide who are at a high-risk for developing Hepatocellular Carcinoma. Due to the fact that reliable parameters and/or too...

journal_title：Journal of Cancer

authors： Abdalla MA,Haj-Ahmad Y

更新日期：2012-01-01 00:00:00

abstract：:Objectives: Lung cancer in young adults is a distinct disease with particular socioeconomic implications. This study aimed to clarify the clinicopathological characteristics, best interventions, and outcomes of this distinctive entity. Methods: A retrospective review of patients with lung cancer was performed in our i...

journal_title：Journal of Cancer

authors： Liu B,Quan X,Xu C,Lv J,Li C,Dong L,Liu M

更新日期：2019-06-09 00:00:00

abstract：:Background & Aims: Primary tumors of colorectal carcinoma (CRC) with liver metastasis might gain some liver-specific characteristics to adapt the liver micro-environment. This study aims to reveal potential liver-like transcriptional characteristics associated with the liver metastasis in primary colorectal carcinoma....

journal_title：Journal of Cancer

authors： Cheng J,Song X,Ao L,Chen R,Chi M,Guo Y,Zhang J,Li H,Zhao W,Guo Z,Wang X

更新日期：2018-04-06 00:00:00

abstract：BACKGROUND:MALAT-1 is significantly overexpressed in various cancers, suggesting that it might be a potential biomarker of cancer. METHODS:A meta-analysis was performed using microarray data obtained via the Affymetrix Human Genome U133 Plus 2.0 platform found in the Gene Expression Omnibus (GEO) database and data obt...

journal_title：Journal of Cancer

authors： Wang Y,Xue D,Li Y,Pan X,Zhang X,Kuang B,Zhou M,Li X,Xiong W,Li G,Zeng Z,Yang T

更新日期：2016-05-20 00:00:00

abstract：:Background: Carbonic anhydrase 4 (CA4) maintains homeostasis of carbon dioxide and bicarbonate. It is suggested to be a potential prognostic biomarker, while the correlations between CA4 and different cancers are indistinct. Methods: Differential mRNA expression of CA4 among different cancers and corresponding normal ...

journal_title：Journal of Cancer

authors： Xu Y,Xu WH,Shi SN,Yang XL,Ren YR,Zhuang XY,Qu YY,Zhang HL,Zhang XF

更新日期：2020-08-25 00:00:00

abstract：:Background and aims. Cyclin-dependent kinase inhibitor 3 (CDKN3) has been found playing a varying role in carcinogenesis, but its biological function in esophageal squamous cell carcinoma (ESCC) is unclear. The aim of this study was to demonstrate the role of CDKN3 in ESCC. Materials and Methods: Real-time PCR and Wes...

journal_title：Journal of Cancer

authors： Liu J,Min L,Zhu S,Guo Q,Li H,Zhang Z,Zhao Y,Xu C,Zhang S

更新日期：2019-04-21 00:00:00

abstract：:Background: The transfusion of blood that has been stored for some time was found to be associated with transfusion-related immune modulation (TRIM) responses in cancer patients, which could result in poor clinical outcomes, such as tumor recurrence, metastasis and reduced survival rate. Given the prior observation of...

journal_title：Journal of Cancer

authors： Zhang J,Chen S,Yan Y,Zhu X,Qi Q,Zhang Y,Zhang Q,Xia R

更新日期：2019-06-02 00:00:00

abstract：:Background: The Aldehyde dehydrogenase 2 (ALDH2) mutant genotypes contain an allele encoding defective ALDH2 with reduced efficacy of alcohol metabolism leading to accumulation of highly toxic and carcinogenic acetaldehyde. It can induce unpleasant "Asian flush syndrome" and associate with increased risk of cancers. H...

journal_title：Journal of Cancer

authors： Huang PH,Hu CC,Chien CH,Chen LW,Chien RN,Lin YS,Chao M,Lin CL,Yeh CT

更新日期：2019-10-03 00:00:00

abstract：:Background: The genetic heterogeneity between primary and metastatic lesions has rarely studied. Purpose: This study aims to compare the mutation profiling of key cancer-related genes in primary lung cancers and their matched lymph nodes (LN) metastasis. Methods: The gene mutation profiling of both primary cancers and...

journal_title：Journal of Cancer

authors： Chen Y,Mao B,Peng X,Zhou Y,Xia K,Guo H,Jiang H,Wang G,Zhuang W

更新日期：2019-03-03 00:00:00

abstract：:Esophageal cancer (EC) is a unique and heterogeneous disease diagnosed mostly at advanced stages. Altered glycans presented on cell surfaces are involved in the occurrence and development of malignancy. However, the effects of glycans on EC progression are largely unexplored. Here, a lectin array was utilized to detec...

journal_title：Journal of Cancer

authors： Xia M,Shao J,Qiao M,Luo Z,Deng X,Ke Q,Dong X,Shen L

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Mathematical models can be useful tools in exploring disease trends and health consequences of interventions in a population over time. Most cancers, in particular cervical cancer, have long incubation periods. The time from acquisition of HPV infection to development of invasive cancer can be up to two deca...

journal_title：Journal of Cancer

authors： Lee SL,Tameru AM

更新日期：2012-01-01 00:00:00

abstract：:Hedgehog (Hh) signalling plays an important role in cancer; however, its mechanism in ovarian cancer migration and invasion remains unclear. In the present study, we aimed to clarify the effect of the Hh signalling pathway on ovarian cancer migration and invasion through the regulation of CD24 expression, both in vitr...

journal_title：Journal of Cancer

authors： Zeng C,Chen T,Zhang Y,Chen Q

更新日期：2017-02-25 00:00:00

abstract：:Background: We previously demonstrated that Proline rich 11 (PRR11) gene is associated with the development and progression of tongue squamous cell carcinoma (TSCC), but the underlying mechanism is unknown. This study aimed to investigate the molecular mechanism underlying oncogenic potential of PRR11 in TSCC cells. M...

journal_title：Journal of Cancer

authors： Wang C,Yu L,Ren X,Wu T,Chen X,Huang Y,Cheng B

更新日期：2019-06-02 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is currently one of the most intractable malignancies with a typical scirrhous pattern in histology. Due to its abundant tumor stroma and scant vascularization, chemotherapeutic agents are considered inefficiently permeable to cancer nests, making it highly difficult to cure the...

journal_title：Journal of Cancer

authors： Saito K,Sakaguchi M,Maruyama S,Iioka H,Putranto EW,Sumardika IW,Tomonobu N,Kawasaki T,Homma K,Kondo E

更新日期：2018-07-30 00:00:00

abstract：:Introduction: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are a standard first-line treatment for advanced EGFR-mutated NSCLC patients. Factors associated with symptoms and quality of life (QOL) improvements have not been investigated. Methods: We conducted a multicenter, prospective study ...

journal_title：Journal of Cancer

authors： Wei YF,Huang WT,Liu TC,Shieh JM,Chian CF,Wu MF,Chang CC,Lin CH,Ko JC,Lin CM,Hsia TC

更新日期：2019-07-10 00:00:00

abstract：:Trend analysis is the analysis using statistical models to estimate and predict potential trends over time, space or any independent continuous-variable. It has been widely used in epidemiology and public health, but much less so in clinical oncology and basic cancer research. Methodological imitations of the chosen s...

journal_title：Journal of Cancer

authors： Xu J,Lin Y,Yang M,Zhang L

更新日期：2020-03-04 00:00:00

abstract：:Purpose: The aberrant of fibroblast growth factors and their receptors (FGF/FGFR) is an emerging target in the treatment of solid tumors. This study aimed to explore the landscape of FGF/FGFR alterations in a large cohort of cancer patients. Material and Methods: The formalin-fixed paraffin-embedded specimens of cance...

journal_title：Journal of Cancer

authors： Zuo W,He Y,Li W,Wu H,Zhao Z,Zhang Y,Chen S,Yin Y

更新日期：2020-09-23 00:00:00

abstract：:Objective: Increasing evidence suggested that dysregulated small nucleolar RNAs (snoRNAs) were involved in tumor development. The roles of snoRNA 71A (SNORA71A) in the progression of non-small cell lung cancer (NSCLC) remained unclear. Methods: Dataset GSE19188 from Gene Expression Omnibus (GEO) database was downloade...

journal_title：Journal of Cancer

authors： Tang G,Zeng Z,Sun W,Li S,You C,Tang F,Peng S,Ma S,Luo Y,Xu J,Tian X,Zhang N,Gong Y,Xie C

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:Statins are proposed as a chemoprevention agent for breast cancer due to their anti-inflammatory effect. The effects of lipophilic and hydrophilic statins on breast cancer risk might be different due to their different pharmacologic properties. Therefore, this study aimed to assess a casual-effect of lipophi...

journal_title：Journal of Cancer

authors： Anothaisintawee T,Udomsubpayakul U,McEvoy M,Lerdsitthichai P,Attia J,Thakkinstian A

更新日期：2016-06-06 00:00:00

abstract：:Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy from surgery, chemotherapy, to radiotherapy. Efforts in recent decades have brought many novel therapies to light, however, with limitations. In...

journal_title：Journal of Cancer

authors： Zhang H,Wang R,Yu Y,Liu J,Luo T,Fan F

更新日期：2019-08-27 00:00:00